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The map label for this gene is yafC [H]

Identifier: 158335415

GI number: 158335415

Start: 2263220

End: 2264113

Strand: Direct

Name: yafC [H]

Synonym: AM1_2260

Alternate gene names: 158335415

Gene position: 2263220-2264113 (Clockwise)

Preceding gene: 158335411

Following gene: 158335416

Centisome position: 34.8

GC content: 51.9

Gene sequence:

>894_bases
ATGAACTGGGATGATTTGAGAATCTTTTTAGCGATTGCCCGTCAAGGATCGGCTCGGGCTGCTGCTGCCAAGCTGGGGGT
TCACCACTCCACCATCACGCGCCGGATTGATGCCTTTGAATCCACCCAGAAAACACGCCTCTTTGATCGGTTACCAAGCG
GGTATGCCCTGACCTTAGCGGGGGAAGAACTACTGGCGGGGGCTACTCGGGTCGAGGACGAAATGAATGGGATTGAACGC
CATATCCTCGGGCAAGATATTCAGCTACGGGGCAATCTCCGCGTCACGATGCCAGATGCTTTAGCGGTTCATTTTCTCAT
GCCAGATTTGGTGTGCTTTATGGAGACTTATCCAGAGGTGAACTTGGAAGTCTTGATTTCCTATGAGGTCTATAACCTCA
CCAAGCGGGAAGCAGATGTTGCCATTCGAGTCACCGAAAATCCGCCTGAACATTTGGTGGGGCGGAAAGTGGGATGTTAT
CACTGCGCCAACTATGCATCTGTAGACTACTTGGCAGCTCATGCACTGCCCAAGAATACTGAAGGGGCCTATTGGATTGG
TTGGGATGCACCAACCCCCTATCCAGACTGGGTGCGAAAGAGTGAGTTTCCCCATATTCCGATGCGGGGGCGATTCAATA
ATGCGATCGCACAACTCGCAGCCGCCAAAGCCGGTTTGGGACTCGCCCGTATCCCCTGTTTTTTAGGCGATCCAGAACCC
ACCCTCAAACGAGTTCCTCCCGGTCAGAGTGCCCCTTGCCATGACGTCTGGATTTTGACCCATAAAGATCTGATCTCAAC
GGTACGTATCCAAACCTTTATGGACTGTATGTCCAAAGCCTTCCAGCAAAAGCAGGATTTATTAGAAGGGCGTTGCCCTG
CACTATCCGCTTAA

Upstream 100 bases:

>100_bases
GATGGTGCCAACTGGCTTTCCTTCGATAGTATGTAATCATTCCTGCATTGAGAAGCCCAAAATAAGCACCCTGCCGTTGC
ATAAATGCACCAGAGGAATC

Downstream 100 bases:

>100_bases
CTCAACACAATCATACGAATCAACCTGTGCAACAGTACCCAATCGAGGACTAGTCGCTATAGGCTACGGCTCTTAAGCTG
AGTTCGAAAGAGCCTCAGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNWDDLRIFLAIARQGSARAAAAKLGVHHSTITRRIDAFESTQKTRLFDRLPSGYALTLAGEELLAGATRVEDEMNGIER
HILGQDIQLRGNLRVTMPDALAVHFLMPDLVCFMETYPEVNLEVLISYEVYNLTKREADVAIRVTENPPEHLVGRKVGCY
HCANYASVDYLAAHALPKNTEGAYWIGWDAPTPYPDWVRKSEFPHIPMRGRFNNAIAQLAAAKAGLGLARIPCFLGDPEP
TLKRVPPGQSAPCHDVWILTHKDLISTVRIQTFMDCMSKAFQQKQDLLEGRCPALSA

Sequences:

>Translated_297_residues
MNWDDLRIFLAIARQGSARAAAAKLGVHHSTITRRIDAFESTQKTRLFDRLPSGYALTLAGEELLAGATRVEDEMNGIER
HILGQDIQLRGNLRVTMPDALAVHFLMPDLVCFMETYPEVNLEVLISYEVYNLTKREADVAIRVTENPPEHLVGRKVGCY
HCANYASVDYLAAHALPKNTEGAYWIGWDAPTPYPDWVRKSEFPHIPMRGRFNNAIAQLAAAKAGLGLARIPCFLGDPEP
TLKRVPPGQSAPCHDVWILTHKDLISTVRIQTFMDCMSKAFQQKQDLLEGRCPALSA
>Mature_297_residues
MNWDDLRIFLAIARQGSARAAAAKLGVHHSTITRRIDAFESTQKTRLFDRLPSGYALTLAGEELLAGATRVEDEMNGIER
HILGQDIQLRGNLRVTMPDALAVHFLMPDLVCFMETYPEVNLEVLISYEVYNLTKREADVAIRVTENPPEHLVGRKVGCY
HCANYASVDYLAAHALPKNTEGAYWIGWDAPTPYPDWVRKSEFPHIPMRGRFNNAIAQLAAAKAGLGLARIPCFLGDPEP
TLKRVPPGQSAPCHDVWILTHKDLISTVRIQTFMDCMSKAFQQKQDLLEGRCPALSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=197, Percent_Identity=28.9340101522843, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787128, Length=181, Percent_Identity=27.0718232044199, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081978, Length=176, Percent_Identity=24.4318181818182, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789440, Length=184, Percent_Identity=24.4565217391304, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33164; Mature: 33164

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWDDLRIFLAIARQGSARAAAAKLGVHHSTITRRIDAFESTQKTRLFDRLPSGYALTLA
CCHHHEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GEELLAGATRVEDEMNGIERHILGQDIQLRGNLRVTMPDALAVHFLMPDLVCFMETYPEV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHCCCC
NLEVLISYEVYNLTKREADVAIRVTENPPEHLVGRKVGCYHCANYASVDYLAAHALPKNT
CEEEEEEEEEHHCCCCCCCEEEEECCCCHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCC
EGAYWIGWDAPTPYPDWVRKSEFPHIPMRGRFNNAIAQLAAAKAGLGLARIPCFLGDPEP
CCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCEECCCCCH
TLKRVPPGQSAPCHDVWILTHKDLISTVRIQTFMDCMSKAFQQKQDLLEGRCPALSA
HHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNWDDLRIFLAIARQGSARAAAAKLGVHHSTITRRIDAFESTQKTRLFDRLPSGYALTLA
CCHHHEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GEELLAGATRVEDEMNGIERHILGQDIQLRGNLRVTMPDALAVHFLMPDLVCFMETYPEV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHCCCC
NLEVLISYEVYNLTKREADVAIRVTENPPEHLVGRKVGCYHCANYASVDYLAAHALPKNT
CEEEEEEEEEHHCCCCCCCEEEEECCCCHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCC
EGAYWIGWDAPTPYPDWVRKSEFPHIPMRGRFNNAIAQLAAAKAGLGLARIPCFLGDPEP
CCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCEECCCCCH
TLKRVPPGQSAPCHDVWILTHKDLISTVRIQTFMDCMSKAFQQKQDLLEGRCPALSA
HHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]