Click here to switch to the map view.

The map label for this gene is rsr [H]

Identifier: 158335359

GI number: 158335359

Start: 2209768

End: 2211363

Strand: Direct

Name: rsr [H]

Synonym: AM1_2204

Alternate gene names: 158335359

Gene position: 2209768-2211363 (Clockwise)

Preceding gene: 158335356

Following gene: 158335366

Centisome position: 33.98

GC content: 53.7

Gene sequence:

>1596_bases
ATGACTTACAAATTTTTTACCAACGCTCGTACCCCTCAGACCCATCCGATTCCTGGCCATGCAGCTGAAATGGTCCAAGG
TCGATCTGGCGGCTACATGTTTGACCCAGGCATTTGGGGGATGCTGCGCCGATGCCTACTGATCGGTACAGCTCAAAGCA
CCTACTATGCAGACAAGCATGAGTTAACCGATGACTTTATCCATGTCGTCCAGCAGTGTGTTTATGAGAATCCTCAGCGC
ACCGCTGAAGAGATTCTCTACGCTAGCGATGGCCGTTCCATCAACAACAGTGCGCCTATCTTGGCATTAGTGCTTTTATC
CATGGGGGAAACCCAAATCGCCAAGCAGGCATTTGTAGAGCTATTCCCGCAAGTGGTGCGAACGGGTAGCCATTTCTACG
AGTGGTTGAACTATACCAAGTCCTTACGGGGTTTCGGTAAAATCATTCGCCAGTGTGGAACCACATGGCTCTCTAATCCC
GATGCCAAGGCCCTGGCCTATCAGTTGCTGAAGTACCAGCAGCGCCATGGCTTTACTCACCGGGATGCCTTACGGCTATT
CCACGTCAAGCCCATCAGTGCCGATCACCAGGCCCTTTATCACTGGGTGACCCAGGGTTGGGAGACCTTACCTGAAAGCG
CTCCTGACGCTTTAAAGCAAATTTGGTGGTACGAGCGGGTCAAGCGTCAGCCCGAGGCTACCCATGAGGCAATTATCCAA
GGTCGCTTAACCCACGAGATGATCGCCCCCATCGGTCAGATGGATCAGCGGGCTTGGCAGCTCCTCTTAGAGGGAATGCC
TGTGGGAGCCTTATTGCGAAATCTAGGGTCTTTGACAGCACTAGGCGTTCTCGGAGCCCATAAGAGTAAGAACCTCAAGC
GAGTGGCTGCGATGTTAACCAACAAGCAGCGCTTGCGCAAGGCTCGGATCCATCCGATTGATGTGCTCAAAGCCTTGAAG
ACCTATGCGTCTGGGGGCCAGGTGGGGCGAAGTCGCAAGACTTGGACACCCATCGCCCGAGTCACCGATATTCTCGAAAC
GGCCCTTGAGCTATCTTTCGAGACAGTTGCCCCAACGGGCAAGGTGTTTATGCATGCCATCGATGTCTCAGGGTCGATGT
CCTACTACACTGTGGGTTCGGTGGGCTTAAGCTGCTGCGAGATTGCCACGGCAATGGCCCTAGCAACGGCCAAAGCTGAG
CGGAACTACGCGATTCGCGGGTTCTCAACCCAGTTCCGTGATTTGGGTATCACAGCCCGAGACAGCTTCCGCGATGCGCT
CAAGAAGGCAACGGATAATAACTTCGGAGGCACTAATGCAGCGGTGGCCTACGAGTGGGCGATTCAGCATCACTTCTATG
CCGATGTCTTCTGCTTCTGGACGGATTCTGAGTCCTATGCAGGGCGACAGCATCCGAGTCAGGCTTTAGCGGAGTATCGA
CGTCTAGTGAATCCAAAGGCTAAGGCGGTTTACGTGACTCTAGCCCCTTACCAGCTCTCCTTAGTGGATCCTAAGGATCC
ATTATCCTGGGACTTCGGTGGTTTCGACCCCGCTGCCCCACGAGCCATCCAAATGATTGCTCAAGGAGAGATCTAA

Upstream 100 bases:

>100_bases
GTCCTTTATCCGTCGGGATGCGGGTTCGACTCCCGCTCCACTCCCTTTCCCTATATGGGATTTTCAGCTTTTTTATTGCC
CAGTCGGGCCGGAGATAATC

Downstream 100 bases:

>100_bases
CAAAGAGAGGTTACTATTCACTTTTTATCAAGGCTTAGTGACCTCTTTCGTATTTTGGATAATAAGATTCAAATGCACCC
ATCAAGTAAGTGGAAAAATC

Product: TROVE domain-containing protein

Products: NA

Alternate protein names: Ro sixty-related protein [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTYKFFTNARTPQTHPIPGHAAEMVQGRSGGYMFDPGIWGMLRRCLLIGTAQSTYYADKHELTDDFIHVVQQCVYENPQR
TAEEILYASDGRSINNSAPILALVLLSMGETQIAKQAFVELFPQVVRTGSHFYEWLNYTKSLRGFGKIIRQCGTTWLSNP
DAKALAYQLLKYQQRHGFTHRDALRLFHVKPISADHQALYHWVTQGWETLPESAPDALKQIWWYERVKRQPEATHEAIIQ
GRLTHEMIAPIGQMDQRAWQLLLEGMPVGALLRNLGSLTALGVLGAHKSKNLKRVAAMLTNKQRLRKARIHPIDVLKALK
TYASGGQVGRSRKTWTPIARVTDILETALELSFETVAPTGKVFMHAIDVSGSMSYYTVGSVGLSCCEIATAMALATAKAE
RNYAIRGFSTQFRDLGITARDSFRDALKKATDNNFGGTNAAVAYEWAIQHHFYADVFCFWTDSESYAGRQHPSQALAEYR
RLVNPKAKAVYVTLAPYQLSLVDPKDPLSWDFGGFDPAAPRAIQMIAQGEI

Sequences:

>Translated_531_residues
MTYKFFTNARTPQTHPIPGHAAEMVQGRSGGYMFDPGIWGMLRRCLLIGTAQSTYYADKHELTDDFIHVVQQCVYENPQR
TAEEILYASDGRSINNSAPILALVLLSMGETQIAKQAFVELFPQVVRTGSHFYEWLNYTKSLRGFGKIIRQCGTTWLSNP
DAKALAYQLLKYQQRHGFTHRDALRLFHVKPISADHQALYHWVTQGWETLPESAPDALKQIWWYERVKRQPEATHEAIIQ
GRLTHEMIAPIGQMDQRAWQLLLEGMPVGALLRNLGSLTALGVLGAHKSKNLKRVAAMLTNKQRLRKARIHPIDVLKALK
TYASGGQVGRSRKTWTPIARVTDILETALELSFETVAPTGKVFMHAIDVSGSMSYYTVGSVGLSCCEIATAMALATAKAE
RNYAIRGFSTQFRDLGITARDSFRDALKKATDNNFGGTNAAVAYEWAIQHHFYADVFCFWTDSESYAGRQHPSQALAEYR
RLVNPKAKAVYVTLAPYQLSLVDPKDPLSWDFGGFDPAAPRAIQMIAQGEI
>Mature_530_residues
TYKFFTNARTPQTHPIPGHAAEMVQGRSGGYMFDPGIWGMLRRCLLIGTAQSTYYADKHELTDDFIHVVQQCVYENPQRT
AEEILYASDGRSINNSAPILALVLLSMGETQIAKQAFVELFPQVVRTGSHFYEWLNYTKSLRGFGKIIRQCGTTWLSNPD
AKALAYQLLKYQQRHGFTHRDALRLFHVKPISADHQALYHWVTQGWETLPESAPDALKQIWWYERVKRQPEATHEAIIQG
RLTHEMIAPIGQMDQRAWQLLLEGMPVGALLRNLGSLTALGVLGAHKSKNLKRVAAMLTNKQRLRKARIHPIDVLKALKT
YASGGQVGRSRKTWTPIARVTDILETALELSFETVAPTGKVFMHAIDVSGSMSYYTVGSVGLSCCEIATAMALATAKAER
NYAIRGFSTQFRDLGITARDSFRDALKKATDNNFGGTNAAVAYEWAIQHHFYADVFCFWTDSESYAGRQHPSQALAEYRR
LVNPKAKAVYVTLAPYQLSLVDPKDPLSWDFGGFDPAAPRAIQMIAQGEI

Specific function: Binds to several small RNAs that accumulate during recovery from UV irradiation. Contributes to the resistance of D.radiodurans to ultraviolet irradiation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TROVE domain [H]

Homologues:

Organism=Homo sapiens, GI291084629, Length=516, Percent_Identity=30.4263565891473, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI31377800, Length=516, Percent_Identity=30.4263565891473, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI291084624, Length=511, Percent_Identity=30.5283757338552, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI291084635, Length=498, Percent_Identity=30.3212851405622, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI108796056, Length=498, Percent_Identity=30.3212851405622, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17557834, Length=589, Percent_Identity=25.8064516129032, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008858 [H]

Pfam domain/function: PF05731 TROVE [H]

EC number: NA

Molecular weight: Translated: 59546; Mature: 59415

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50988 TROVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKFFTNARTPQTHPIPGHAAEMVQGRSGGYMFDPGIWGMLRRCLLIGTAQSTYYADKH
CCEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCHHEECCHH
ELTDDFIHVVQQCVYENPQRTAEEILYASDGRSINNSAPILALVLLSMGETQIAKQAFVE
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
LFPQVVRTGSHFYEWLNYTKSLRGFGKIIRQCGTTWLSNPDAKALAYQLLKYQQRHGFTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCH
RDALRLFHVKPISADHQALYHWVTQGWETLPESAPDALKQIWWYERVKRQPEATHEAIIQ
HHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
GRLTHEMIAPIGQMDQRAWQLLLEGMPVGALLRNLGSLTALGVLGAHKSKNLKRVAAMLT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NKQRLRKARIHPIDVLKALKTYASGGQVGRSRKTWTPIARVTDILETALELSFETVAPTG
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
KVFMHAIDVSGSMSYYTVGSVGLSCCEIATAMALATAKAERNYAIRGFSTQFRDLGITAR
CEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHH
DSFRDALKKATDNNFGGTNAAVAYEWAIQHHFYADVFCFWTDSESYAGRQHPSQALAEYR
HHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHH
RLVNPKAKAVYVTLAPYQLSLVDPKDPLSWDFGGFDPAAPRAIQMIAQGEI
HHCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TYKFFTNARTPQTHPIPGHAAEMVQGRSGGYMFDPGIWGMLRRCLLIGTAQSTYYADKH
CEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCHHEECCHH
ELTDDFIHVVQQCVYENPQRTAEEILYASDGRSINNSAPILALVLLSMGETQIAKQAFVE
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
LFPQVVRTGSHFYEWLNYTKSLRGFGKIIRQCGTTWLSNPDAKALAYQLLKYQQRHGFTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCH
RDALRLFHVKPISADHQALYHWVTQGWETLPESAPDALKQIWWYERVKRQPEATHEAIIQ
HHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
GRLTHEMIAPIGQMDQRAWQLLLEGMPVGALLRNLGSLTALGVLGAHKSKNLKRVAAMLT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NKQRLRKARIHPIDVLKALKTYASGGQVGRSRKTWTPIARVTDILETALELSFETVAPTG
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
KVFMHAIDVSGSMSYYTVGSVGLSCCEIATAMALATAKAERNYAIRGFSTQFRDLGITAR
CEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHH
DSFRDALKKATDNNFGGTNAAVAYEWAIQHHFYADVFCFWTDSESYAGRQHPSQALAEYR
HHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHH
RLVNPKAKAVYVTLAPYQLSLVDPKDPLSWDFGGFDPAAPRAIQMIAQGEI
HHCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266; 10766734 [H]