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The map label for this gene is clpB [H]

Identifier: 158335282

GI number: 158335282

Start: 2114793

End: 2117420

Strand: Direct

Name: clpB [H]

Synonym: AM1_2125

Alternate gene names: 158335282

Gene position: 2114793-2117420 (Clockwise)

Preceding gene: 158335278

Following gene: 158335285

Centisome position: 32.52

GC content: 50.23

Gene sequence:

>2628_bases
ATGCAACCCACCAATCATGACCAATTTACGGAAAAAGCTTGGGCTGCGATTGTACGAACCTCTGACTTGGCGAAAGAGGC
CCAGCAACAGCAGATTGAGAGTGAACATCTGCTGCAAGCCCTGGTTGAAGACGATGGTTTAGCAGGACAAATTTTTACTA
AAGCCGGGACAGATGTGCAGCGCGTCCGCGATCGCACCACGGAATTTATCAATCGGCAAGCGAAACTCACCACACCGAGT
GAGTCAGTTTATCTAGGTCGCAGCCTAGACACCCTCTTTGATCGGGCCGAAAACTTCCGCCGCTCGCTTGGGGATGATTT
TATTTCCATTGAGCACTTGGTCTTGGGCTATATCGAAGATGATCGCTTCGGCCAACCCCTCCTCCAAGGTCTGGGCATCA
CCGAGCAAATGTTGAAGCAAGCTGTTACAGACATCCGGGGAAATCATAAAGTCACGGATAAGAATCCAGAAGGCAAGTAT
GAGTCCTTAGAGAAATATGGTCGTGACCTAACAGCGCTGGCTCGGGAAGGAAAGTTGGACCCGGTGATTGGCCGAGATGA
CGAGATCCGCAGAACGATTCAAATCCTCTCCCGACGCACGAAGAATAACCCCGTCTTGATTGGGGAACCTGGGGTGGGTA
AAACAGCCATTGCCGAAGGGTTAGCCCAGCGAATTGTGGCCCGAGATGTCCCGGAATCTTTGCGAGATCGCAAACTGATT
GCCCTTGACATGGGATCCCTGATTGCCGGGGCCAAATATCGGGGAGAATTCGAGGAACGACTCAAGTCTGTCCTTAAGGA
AGTGACGGAGTCAGACGGGTTGATGATCTTATTTATTGATGAGATCCATACCGTCGTTGGCGCAGGGGCCAGTCAAGGTG
CCATGGATGCGGGCAACTTGTTAAAGCCCATGCTGGCCCGAGGGGAATTGCGCTGTATTGGAGCCACCACCCTCGATGAA
TATCGCAAATATATTGAAAAAGATGCGGCCCTAGAGCGACGCTTTCAGCAGGTCTATATTGATCAACCCAATATTCAAGA
CACCGTCTCAATTTTGCGGGGTCTAAAAGAACGGTATGAGGTCCATCACGGGGTCAAGATTTCTGATAACGCCCTGGTTG
CCGCCGCCACTCTTTCTACCCGCTACATCAGCGACCGCTTTTTACCTGACAAGGCTATTGACCTAATGGATGAAGCGGCA
GCCAAGCTCAAAATGGAAATTACCTCTAAGCCGGAAGAGCTAGACGAAATTGATCGTAAAATCCTCCAGCTGGAAATGGA
GCGTTTATCCCTTGAAAAGGAAAGCGATCGCGCTTCTCTAGAACGCCTCGAACGAATCGAGCAGGAGATTGCCAACCTAC
AAGAAGATCAAAAGACCCTGAATGCCCAATGGCAGTCTGAGAAACAAATTATTGATGATATCCAAACCATCAAAGAAGAA
ATTGATCGGGTCAATATTGAGATTCAGCAGGCTGAGCGCAACTATGATCTCAACCATGCAGCTGAACTGAAATATGGCAA
ACTCACTAATTTGCAGCGGCAGCTAGAATCGGCTGAAACTCAGCTAGCCCAGCGCCAAACCAATACCAACTCCCTTTTAA
GAGAAGAGGTAACCGATGCTGATATTGCCGAAATCATCTCTAAATGGACGGGGATTCCCGTCAGTAAGCTGGTGGCGTCG
GAAATGGAAAAGCTGCTGCACCTAGAAGATGAGCTACATCAGCGAGTGATTGGCCAGGAAGAAGCAGTGACGGCCGTGTC
TGATGCGATTCAGCGATCGCGTGCCGGTCTCGCAGATCCCAACCGCCCCATTGCCAGCTTTATCTTCTTAGGTCCAACGG
GTGTGGGCAAAACAGAACTAGGCAAAGCTTTAGCCGCCTACCTATTTGATACCGAAGATGCCATGGTCCGTATCGACATG
TCGGAATATATGGAGAAGCATACGGTGGCCCGGATGATTGGGGCCCCTCCCGGCTATGTCGGCTATGACGAAGGGGGGCA
ACTGACTGAAGCCGTTCGTCGCCGTCCCTATGCGGTCATCCTCTTTGATGAAATTGAGAAGGCCCATCCCGATGTCTTCA
ATATCATGCTGCAAATTCTGGATGATGGCCGAGTCACGGATTCCCAAGGTCGCACTGTCGACTTTAAGAATGCGGTGATT
ATTATGACCAGTAATATTGGCTCCCAACATATTTTAGATTTGGCGGGAGATGACAGCCGCTACAGCGAAATGCAAAATCG
GGTTATGGATGCCATGCGCTCCCACTTCCGACCTGAATTTCTGAACCGGATTGATGAGCTGATTATCTTCCGTAGTCTGC
GTAAGGATCAGTTGCGCCGAATTACTCAACTCCAGGTTCAACGACTGGCGAAACGACTCAGCGATCGCAAGATGTCTCTC
AAACTCTCAGAATCAGCGTTAGATTTCCTAGCAGAAGTTGGATACGACCCGGTCTATGGGGCCAGACCGCTGAAACGGGC
CATTCAGCGGGAGCTAGAAACCCAAATTGCCAAGGCCATTTTGCGAGGTGACTTTGGTGAAGGAGACACCATTTTTGCGG
ATGTCGAGAATGAGCGGTTGATCTTTAAGCGCATGGGGGCAGAAGTCTTGACCACTTCGGGTTCATAG

Upstream 100 bases:

>100_bases
GGGAAGACCGATCTTAGGCAATGTCCTCCCCTCTCTACAATGGCAGTAGGCGCTAGGCCTGCCAGAAGTTAATCCCCACT
GTCCAGGAGGTTCCCCATTC

Downstream 100 bases:

>100_bases
CACTATTGACAACCTAGACCATAATCGAACCCCCTAGAACTATCGTTCTAGGGGGCTTTGAGTGAGGAGTTAATGCGAGG
AGTGAAAAGACTACATCAGG

Product: chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 875; Mature: 875

Protein sequence:

>875_residues
MQPTNHDQFTEKAWAAIVRTSDLAKEAQQQQIESEHLLQALVEDDGLAGQIFTKAGTDVQRVRDRTTEFINRQAKLTTPS
ESVYLGRSLDTLFDRAENFRRSLGDDFISIEHLVLGYIEDDRFGQPLLQGLGITEQMLKQAVTDIRGNHKVTDKNPEGKY
ESLEKYGRDLTALAREGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVARDVPESLRDRKLI
ALDMGSLIAGAKYRGEFEERLKSVLKEVTESDGLMILFIDEIHTVVGAGASQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYIDQPNIQDTVSILRGLKERYEVHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAA
AKLKMEITSKPEELDEIDRKILQLEMERLSLEKESDRASLERLERIEQEIANLQEDQKTLNAQWQSEKQIIDDIQTIKEE
IDRVNIEIQQAERNYDLNHAAELKYGKLTNLQRQLESAETQLAQRQTNTNSLLREEVTDADIAEIISKWTGIPVSKLVAS
EMEKLLHLEDELHQRVIGQEEAVTAVSDAIQRSRAGLADPNRPIASFIFLGPTGVGKTELGKALAAYLFDTEDAMVRIDM
SEYMEKHTVARMIGAPPGYVGYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNIMLQILDDGRVTDSQGRTVDFKNAVI
IMTSNIGSQHILDLAGDDSRYSEMQNRVMDAMRSHFRPEFLNRIDELIIFRSLRKDQLRRITQLQVQRLAKRLSDRKMSL
KLSESALDFLAEVGYDPVYGARPLKRAIQRELETQIAKAILRGDFGEGDTIFADVENERLIFKRMGAEVLTTSGS

Sequences:

>Translated_875_residues
MQPTNHDQFTEKAWAAIVRTSDLAKEAQQQQIESEHLLQALVEDDGLAGQIFTKAGTDVQRVRDRTTEFINRQAKLTTPS
ESVYLGRSLDTLFDRAENFRRSLGDDFISIEHLVLGYIEDDRFGQPLLQGLGITEQMLKQAVTDIRGNHKVTDKNPEGKY
ESLEKYGRDLTALAREGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVARDVPESLRDRKLI
ALDMGSLIAGAKYRGEFEERLKSVLKEVTESDGLMILFIDEIHTVVGAGASQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYIDQPNIQDTVSILRGLKERYEVHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAA
AKLKMEITSKPEELDEIDRKILQLEMERLSLEKESDRASLERLERIEQEIANLQEDQKTLNAQWQSEKQIIDDIQTIKEE
IDRVNIEIQQAERNYDLNHAAELKYGKLTNLQRQLESAETQLAQRQTNTNSLLREEVTDADIAEIISKWTGIPVSKLVAS
EMEKLLHLEDELHQRVIGQEEAVTAVSDAIQRSRAGLADPNRPIASFIFLGPTGVGKTELGKALAAYLFDTEDAMVRIDM
SEYMEKHTVARMIGAPPGYVGYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNIMLQILDDGRVTDSQGRTVDFKNAVI
IMTSNIGSQHILDLAGDDSRYSEMQNRVMDAMRSHFRPEFLNRIDELIIFRSLRKDQLRRITQLQVQRLAKRLSDRKMSL
KLSESALDFLAEVGYDPVYGARPLKRAIQRELETQIAKAILRGDFGEGDTIFADVENERLIFKRMGAEVLTTSGS
>Mature_875_residues
MQPTNHDQFTEKAWAAIVRTSDLAKEAQQQQIESEHLLQALVEDDGLAGQIFTKAGTDVQRVRDRTTEFINRQAKLTTPS
ESVYLGRSLDTLFDRAENFRRSLGDDFISIEHLVLGYIEDDRFGQPLLQGLGITEQMLKQAVTDIRGNHKVTDKNPEGKY
ESLEKYGRDLTALAREGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVARDVPESLRDRKLI
ALDMGSLIAGAKYRGEFEERLKSVLKEVTESDGLMILFIDEIHTVVGAGASQGAMDAGNLLKPMLARGELRCIGATTLDE
YRKYIEKDAALERRFQQVYIDQPNIQDTVSILRGLKERYEVHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAA
AKLKMEITSKPEELDEIDRKILQLEMERLSLEKESDRASLERLERIEQEIANLQEDQKTLNAQWQSEKQIIDDIQTIKEE
IDRVNIEIQQAERNYDLNHAAELKYGKLTNLQRQLESAETQLAQRQTNTNSLLREEVTDADIAEIISKWTGIPVSKLVAS
EMEKLLHLEDELHQRVIGQEEAVTAVSDAIQRSRAGLADPNRPIASFIFLGPTGVGKTELGKALAAYLFDTEDAMVRIDM
SEYMEKHTVARMIGAPPGYVGYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNIMLQILDDGRVTDSQGRTVDFKNAVI
IMTSNIGSQHILDLAGDDSRYSEMQNRVMDAMRSHFRPEFLNRIDELIIFRSLRKDQLRRITQLQVQRLAKRLSDRKMSL
KLSESALDFLAEVGYDPVYGARPLKRAIQRELETQIAKAILRGDFGEGDTIFADVENERLIFKRMGAEVLTTSGS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=319, Percent_Identity=39.1849529780564, Blast_Score=221, Evalue=2e-57,
Organism=Escherichia coli, GI1788943, Length=856, Percent_Identity=55.7242990654206, Blast_Score=959, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=254, Percent_Identity=54.3307086614173, Blast_Score=284, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.1067415730337, Blast_Score=771, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=860, Percent_Identity=42.906976744186, Blast_Score=692, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 98890; Mature: 98890

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTNHDQFTEKAWAAIVRTSDLAKEAQQQQIESEHLLQALVEDDGLAGQIFTKAGTDVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHH
RVRDRTTEFINRQAKLTTPSESVYLGRSLDTLFDRAENFRRSLGDDFISIEHLVLGYIED
HHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DRFGQPLLQGLGITEQMLKQAVTDIRGNHKVTDKNPEGKYESLEKYGRDLTALAREGKLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCC
PVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVARDVPESLRDRKLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHCCEEE
ALDMGSLIAGAKYRGEFEERLKSVLKEVTESDGLMILFIDEIHTVVGAGASQGAMDAGNL
EEEHHHHHHCCHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYIDQPNIQDTVSILRGLKERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAAAKLKMEITSKPEELDEIDRK
HHCCEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHH
ILQLEMERLSLEKESDRASLERLERIEQEIANLQEDQKTLNAQWQSEKQIIDDIQTIKEE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDRVNIEIQQAERNYDLNHAAELKYGKLTNLQRQLESAETQLAQRQTNTNSLLREEVTDA
HHHHCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DIAEIISKWTGIPVSKLVASEMEKLLHLEDELHQRVIGQEEAVTAVSDAIQRSRAGLADP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NRPIASFIFLGPTGVGKTELGKALAAYLFDTEDAMVRIDMSEYMEKHTVARMIGAPPGYV
CCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNIMLQILDDGRVTDSQGRTVDFKNAVI
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSQHILDLAGDDSRYSEMQNRVMDAMRSHFRPEFLNRIDELIIFRSLRKDQLRR
EEECCCCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ITQLQVQRLAKRLSDRKMSLKLSESALDFLAEVGYDPVYGARPLKRAIQRELETQIAKAI
HHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGDFGEGDTIFADVENERLIFKRMGAEVLTTSGS
HHCCCCCCCEEEEECCCCHHHHHHHCCHHCCCCCC
>Mature Secondary Structure
MQPTNHDQFTEKAWAAIVRTSDLAKEAQQQQIESEHLLQALVEDDGLAGQIFTKAGTDVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHH
RVRDRTTEFINRQAKLTTPSESVYLGRSLDTLFDRAENFRRSLGDDFISIEHLVLGYIED
HHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DRFGQPLLQGLGITEQMLKQAVTDIRGNHKVTDKNPEGKYESLEKYGRDLTALAREGKLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCC
PVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVARDVPESLRDRKLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHCCEEE
ALDMGSLIAGAKYRGEFEERLKSVLKEVTESDGLMILFIDEIHTVVGAGASQGAMDAGNL
EEEHHHHHHCCHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYIDQPNIQDTVSILRGLKERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VHHGVKISDNALVAAATLSTRYISDRFLPDKAIDLMDEAAAKLKMEITSKPEELDEIDRK
HHCCEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHH
ILQLEMERLSLEKESDRASLERLERIEQEIANLQEDQKTLNAQWQSEKQIIDDIQTIKEE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDRVNIEIQQAERNYDLNHAAELKYGKLTNLQRQLESAETQLAQRQTNTNSLLREEVTDA
HHHHCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DIAEIISKWTGIPVSKLVASEMEKLLHLEDELHQRVIGQEEAVTAVSDAIQRSRAGLADP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NRPIASFIFLGPTGVGKTELGKALAAYLFDTEDAMVRIDMSEYMEKHTVARMIGAPPGYV
CCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNIMLQILDDGRVTDSQGRTVDFKNAVI
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSQHILDLAGDDSRYSEMQNRVMDAMRSHFRPEFLNRIDELIIFRSLRKDQLRR
EEECCCCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ITQLQVQRLAKRLSDRKMSLKLSESALDFLAEVGYDPVYGARPLKRAIQRELETQIAKAI
HHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGDFGEGDTIFADVENERLIFKRMGAEVLTTSGS
HHCCCCCCCEEEEECCCCHHHHHHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]