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The map label for this gene is ychM [C]

Identifier: 158335269

GI number: 158335269

Start: 2099251

End: 2100978

Strand: Reverse

Name: ychM [C]

Synonym: AM1_2112

Alternate gene names: 158335269

Gene position: 2100978-2099251 (Counterclockwise)

Preceding gene: 158335270

Following gene: 158335268

Centisome position: 32.3

GC content: 52.95

Gene sequence:

>1728_bases
GTGGCTAAGAACGGCAAGTCTGGGCTGCGATCACGGGTACCGGGTTGGTGGCAGCTGACCCATTATCAATGGCAGTGGTT
GCGGCAGGATAGTATCGCGGGTATAACGGTCGCGGCTTATTTGATTCCTCAATGTATGGCCTATGGGGAGTTAGCGGGGG
TGGAGCCTGTGGCTGGCTTGTGGGCTATTTTGCCTGCCATGCTGATCTACGCGATGTTTGGATCTTCGTTGCAACTCTCC
TTAGGACCTGAGTCGACAACCGCTGTGATGACGGCGGTCGCCATTGGGCCTTTAGTGGCCGGTGGAGCCTATGAGGCGGC
GAGTTGGGCTGCGGTCTTAGCCCTGTTTGTCGGATTGGTTTATTTGATTGCTTATATCGCTCGACTGGGCTTTCTGGCTG
ATTTACTGTCGAAGCCCATTTTAGTGGGATATATGGCAGGAGTCGCCCTGATTATGATCATTGGTCAGCTCGGTAAGGTT
AGCGGTATTCCCATTCAATCTGAGAGTTTGGTGGGAGAGGTGCAAGACTTTGTGACCCAATTCAATCAGCTGCATCCACC
GACCTTTGTGTTGGCAACCGCTGTCTTGTTTTTTCTCTTTGTGATTCAAACTCGCTTTCCCAAATGGCCGGGGCCGCTGA
TTGCAGTTTTATTGGCAACGGCAGCGGTCGCTGTTTTTCAGCTCGATCAGCAAGGCGTCAAGGTGGTAGGCACCATCCCA
GCGGGTTTGCCCACGCCACTCCTGCCCGGATTCTCACCTGCCAAAATTTCTACTTTGCTCGCGGCAGCAGTGGGCATTGC
CGTGGTGGGATATTCGGATAATGTATTGACGGCCCGATCCTTTGCTAACCGTAATGGCTACCAAATCGACGGGAATCAAG
AACTGTTGGCCTTAGGCATCGCGAATTTGGCCACGGGGCTGCTGCAAGGCTTCCCCATCAGCAGCAGTGGTAGCCGTACC
GTGATTGGTGATGCGTTGGGGAGTAAGACCCAAGTGTTTTCCTTGGTCGCGTTTGGGGTGGTGGTCATTGTTTTGCTGTT
TCTACGGCCTGTACTGGCGCTCTTCCCGACCGCAGCCCTCGGGGCAATTGTAATCTTTGCGGCGACCCGACTGATTGAAT
GGGCAGAATTTAAGCGACTCTGGCGGTTTCGAAAAACGGAGTGGGGGTTAGCCATCATCACGACGTTAGGCGTGTTGGGA
ACGGATATTTTACTGGGGGTGGCGGTGGCCGTGGGCTTGTCGGTGATTGATCTGTTTGCTCGGATTGCTCGCCCCCATGA
TGCCGTGTTGGGGAAAGTTCCTGGCATGGCTGGCCTCCATGATATTGCCGATTGGGAGGGGACGGCGACCTGGCCAGGTT
TAGTGATTTATCGCTATGATGCGCCCCTTTGTTTTGCCAATGCCGAAAATTTTAAGCAGCGAGTCTTGGATGCGATCGCA
ACTGAAGAACCCCCTGTCCACTGGTTTGTCCTCAATACGGAAGCCATTATCAATATTGATATTACGGCGGTCGATATGCT
GGAAGAGCTGCGTCAAGAACTCGCTAAGCACAACATTCAGTTTGGCATTGCCCGGATGAAACAAGACCTTTATGGTCAGC
TGCAGCCCACCGCTTTTCTGAAAAACATTCCGCCAGAGTTCATTTTTGCCACGCTACCCACAGCAGTCTCGGCCTATACG
ACCCAATACCCCGTGTCTGCTAATCCTTTGGATCAATCTTCTACATGA

Upstream 100 bases:

>100_bases
GCGATATTTATCAGCCCAGTCACAGGTCTGAGATGGCCTAGCGCCATTGCTGTAATCAAATCAAGCTAATATCAATCCAG
ACTGAACTGAAGCATAAACT

Downstream 100 bases:

>100_bases
ACTTTTTAGCCCATCTCTACCTAGCTCAGCCGACCGTTGAACATCGGTTAGGCAACTTACTCGCAGACTTCATTAAAGGG
GCGGTCCGTCAACAGTTCTC

Product: sulfate permease

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MAKNGKSGLRSRVPGWWQLTHYQWQWLRQDSIAGITVAAYLIPQCMAYGELAGVEPVAGLWAILPAMLIYAMFGSSLQLS
LGPESTTAVMTAVAIGPLVAGGAYEAASWAAVLALFVGLVYLIAYIARLGFLADLLSKPILVGYMAGVALIMIIGQLGKV
SGIPIQSESLVGEVQDFVTQFNQLHPPTFVLATAVLFFLFVIQTRFPKWPGPLIAVLLATAAVAVFQLDQQGVKVVGTIP
AGLPTPLLPGFSPAKISTLLAAAVGIAVVGYSDNVLTARSFANRNGYQIDGNQELLALGIANLATGLLQGFPISSSGSRT
VIGDALGSKTQVFSLVAFGVVVIVLLFLRPVLALFPTAALGAIVIFAATRLIEWAEFKRLWRFRKTEWGLAIITTLGVLG
TDILLGVAVAVGLSVIDLFARIARPHDAVLGKVPGMAGLHDIADWEGTATWPGLVIYRYDAPLCFANAENFKQRVLDAIA
TEEPPVHWFVLNTEAIINIDITAVDMLEELRQELAKHNIQFGIARMKQDLYGQLQPTAFLKNIPPEFIFATLPTAVSAYT
TQYPVSANPLDQSST

Sequences:

>Translated_575_residues
MAKNGKSGLRSRVPGWWQLTHYQWQWLRQDSIAGITVAAYLIPQCMAYGELAGVEPVAGLWAILPAMLIYAMFGSSLQLS
LGPESTTAVMTAVAIGPLVAGGAYEAASWAAVLALFVGLVYLIAYIARLGFLADLLSKPILVGYMAGVALIMIIGQLGKV
SGIPIQSESLVGEVQDFVTQFNQLHPPTFVLATAVLFFLFVIQTRFPKWPGPLIAVLLATAAVAVFQLDQQGVKVVGTIP
AGLPTPLLPGFSPAKISTLLAAAVGIAVVGYSDNVLTARSFANRNGYQIDGNQELLALGIANLATGLLQGFPISSSGSRT
VIGDALGSKTQVFSLVAFGVVVIVLLFLRPVLALFPTAALGAIVIFAATRLIEWAEFKRLWRFRKTEWGLAIITTLGVLG
TDILLGVAVAVGLSVIDLFARIARPHDAVLGKVPGMAGLHDIADWEGTATWPGLVIYRYDAPLCFANAENFKQRVLDAIA
TEEPPVHWFVLNTEAIINIDITAVDMLEELRQELAKHNIQFGIARMKQDLYGQLQPTAFLKNIPPEFIFATLPTAVSAYT
TQYPVSANPLDQSST
>Mature_574_residues
AKNGKSGLRSRVPGWWQLTHYQWQWLRQDSIAGITVAAYLIPQCMAYGELAGVEPVAGLWAILPAMLIYAMFGSSLQLSL
GPESTTAVMTAVAIGPLVAGGAYEAASWAAVLALFVGLVYLIAYIARLGFLADLLSKPILVGYMAGVALIMIIGQLGKVS
GIPIQSESLVGEVQDFVTQFNQLHPPTFVLATAVLFFLFVIQTRFPKWPGPLIAVLLATAAVAVFQLDQQGVKVVGTIPA
GLPTPLLPGFSPAKISTLLAAAVGIAVVGYSDNVLTARSFANRNGYQIDGNQELLALGIANLATGLLQGFPISSSGSRTV
IGDALGSKTQVFSLVAFGVVVIVLLFLRPVLALFPTAALGAIVIFAATRLIEWAEFKRLWRFRKTEWGLAIITTLGVLGT
DILLGVAVAVGLSVIDLFARIARPHDAVLGKVPGMAGLHDIADWEGTATWPGLVIYRYDAPLCFANAENFKQRVLDAIAT
EEPPVHWFVLNTEAIINIDITAVDMLEELRQELAKHNIQFGIARMKQDLYGQLQPTAFLKNIPPEFIFATLPTAVSAYTT
QYPVSANPLDQSST

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721255, Length=480, Percent_Identity=30.625, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI94721259, Length=480, Percent_Identity=30.625, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI94721253, Length=480, Percent_Identity=30.625, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI94721257, Length=480, Percent_Identity=30.625, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI39752683, Length=483, Percent_Identity=28.5714285714286, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI45827800, Length=483, Percent_Identity=28.5714285714286, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI262206105, Length=557, Percent_Identity=26.7504488330341, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI262206075, Length=557, Percent_Identity=26.7504488330341, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI262206069, Length=557, Percent_Identity=26.7504488330341, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI262206063, Length=557, Percent_Identity=26.7504488330341, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI269784651, Length=482, Percent_Identity=28.0082987551867, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4557535, Length=556, Percent_Identity=24.2805755395683, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI45827802, Length=433, Percent_Identity=28.6374133949192, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4505697, Length=502, Percent_Identity=26.2948207171315, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI16418413, Length=486, Percent_Identity=26.9547325102881, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI217272867, Length=481, Percent_Identity=27.2349272349272, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI100913030, Length=612, Percent_Identity=22.5490196078431, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI47131207, Length=509, Percent_Identity=27.5049115913556, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI20336272, Length=509, Percent_Identity=27.5049115913556, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI20336282, Length=508, Percent_Identity=23.8188976377953, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI16306483, Length=509, Percent_Identity=23.7721021611002, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI16418457, Length=610, Percent_Identity=22.4590163934426, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI301601599, Length=610, Percent_Identity=22.4590163934426, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI65506789, Length=381, Percent_Identity=29.3963254593176, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI301601602, Length=355, Percent_Identity=21.9718309859155, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551690, Length=577, Percent_Identity=27.5563258232236, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17566848, Length=604, Percent_Identity=28.1456953642384, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI86565215, Length=596, Percent_Identity=25.6711409395973, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17562578, Length=522, Percent_Identity=28.1609195402299, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI86564196, Length=618, Percent_Identity=25.5663430420712, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI86564876, Length=559, Percent_Identity=23.0769230769231, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI193203292, Length=517, Percent_Identity=23.9845261121857, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI86565211, Length=253, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86565209, Length=243, Percent_Identity=30.0411522633745, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86565213, Length=272, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=566, Percent_Identity=24.3816254416961, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319771, Length=489, Percent_Identity=26.3803680981595, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323121, Length=474, Percent_Identity=24.6835443037975, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24649801, Length=469, Percent_Identity=28.3582089552239, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19922482, Length=536, Percent_Identity=25, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24666186, Length=394, Percent_Identity=29.9492385786802, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24651449, Length=580, Percent_Identity=22.7586206896552, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21358229, Length=583, Percent_Identity=25.3859348198971, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI85815873, Length=527, Percent_Identity=24.2884250474383, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24663084, Length=548, Percent_Identity=25.7299270072993, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357695, Length=548, Percent_Identity=25.7299270072993, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24647160, Length=536, Percent_Identity=24.0671641791045, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355087, Length=536, Percent_Identity=24.0671641791045, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21358633, Length=556, Percent_Identity=23.3812949640288, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61596; Mature: 61465

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNGKSGLRSRVPGWWQLTHYQWQWLRQDSIAGITVAAYLIPQCMAYGELAGVEPVAGL
CCCCCCCHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
WAILPAMLIYAMFGSSLQLSLGPESTTAVMTAVAIGPLVAGGAYEAASWAAVLALFVGLV
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YLIAYIARLGFLADLLSKPILVGYMAGVALIMIIGQLGKVSGIPIQSESLVGEVQDFVTQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FNQLHPPTFVLATAVLFFLFVIQTRFPKWPGPLIAVLLATAAVAVFQLDQQGVKVVGTIP
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
AGLPTPLLPGFSPAKISTLLAAAVGIAVVGYSDNVLTARSFANRNGYQIDGNQELLALGI
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCCEEECCCCHHHHHHH
ANLATGLLQGFPISSSGSRTVIGDALGSKTQVFSLVAFGVVVIVLLFLRPVLALFPTAAL
HHHHHHHHHCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIVIFAATRLIEWAEFKRLWRFRKTEWGLAIITTLGVLGTDILLGVAVAVGLSVIDLFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARPHDAVLGKVPGMAGLHDIADWEGTATWPGLVIYRYDAPLCFANAENFKQRVLDAIA
HHCCCHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHH
TEEPPVHWFVLNTEAIINIDITAVDMLEELRQELAKHNIQFGIARMKQDLYGQLQPTAFL
CCCCCEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHH
KNIPPEFIFATLPTAVSAYTTQYPVSANPLDQSST
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKNGKSGLRSRVPGWWQLTHYQWQWLRQDSIAGITVAAYLIPQCMAYGELAGVEPVAGL
CCCCCCHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
WAILPAMLIYAMFGSSLQLSLGPESTTAVMTAVAIGPLVAGGAYEAASWAAVLALFVGLV
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YLIAYIARLGFLADLLSKPILVGYMAGVALIMIIGQLGKVSGIPIQSESLVGEVQDFVTQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FNQLHPPTFVLATAVLFFLFVIQTRFPKWPGPLIAVLLATAAVAVFQLDQQGVKVVGTIP
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
AGLPTPLLPGFSPAKISTLLAAAVGIAVVGYSDNVLTARSFANRNGYQIDGNQELLALGI
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCCEEECCCCHHHHHHH
ANLATGLLQGFPISSSGSRTVIGDALGSKTQVFSLVAFGVVVIVLLFLRPVLALFPTAAL
HHHHHHHHHCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIVIFAATRLIEWAEFKRLWRFRKTEWGLAIITTLGVLGTDILLGVAVAVGLSVIDLFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARPHDAVLGKVPGMAGLHDIADWEGTATWPGLVIYRYDAPLCFANAENFKQRVLDAIA
HHCCCHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHH
TEEPPVHWFVLNTEAIINIDITAVDMLEELRQELAKHNIQFGIARMKQDLYGQLQPTAFL
CCCCCEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHH
KNIPPEFIFATLPTAVSAYTTQYPVSANPLDQSST
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]