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The map label for this gene is appC [H]

Identifier: 158335236

GI number: 158335236

Start: 2069799

End: 2070716

Strand: Reverse

Name: appC [H]

Synonym: AM1_2079

Alternate gene names: 158335236

Gene position: 2070716-2069799 (Counterclockwise)

Preceding gene: 158335237

Following gene: 158335233

Centisome position: 31.84

GC content: 48.37

Gene sequence:

>918_bases
ATGACCCGCGTTCATAACCTTTATTGGGAAGCTGCCCAAAAGCTCAGCCGTCAAAAACTGGTTGTCATCTGCTTGGGGAT
TATCGCTATCTACATTTTGGTGGCTGTATTGGGGGGATTTAATGTCTTACCTGACTATCAGACTCGGGTGGGGGCAGAAT
ATGAAGCCCCTTCGTTAGAACTCGCAAAATTACTCGGCACCGATCTGTTTGGTCGCTCTGTTCTCTATAAAATTTTGGCT
GGAACTAAAACAGCAATGCTGATTGGAGTCTTAGTGACCAGCATCTCTGTTCCCATCGGTGTCATTTTAGGCGCCTTGGC
GGGCTATTACGGGGGCTTAGTCGATGTTGGCATTGTCTGGCTGTATACCGTCATTAGTTCTGTACCCTACATTTTGATGG
TAATTGCCATCTCCTATGTGATTGGTAAGGGGCTAGTGGCGATTTGTTTGGCTATGGGCCTGCTCGGTTGGGTGGGACTC
TGTCGATTGATACGGAGCGAGGTACTTAAAACCCGCAATTTGGAATATGTGGCTGCTGCCCGAGTGATTGGGGCCAATGA
TCTTCAGATTATATTTAGTCATATCCTCCCCAATGTCATCCATTTGGCGATTATTAGTGCGTCCCTCCAAATTTTGGGCG
CGATCAAGTCGGAAGTGATTCTGACCTATATCGGGGTGGGTATTCAGGATGGAGCGAGCTGGGGCGCCATGATTTCAGAT
GCTACTGGGGAGTTAGTTCAGGGCATTTGGTGGCCTTTGGCAGGGGTGGTGTTAGCCATGTTTTTGTTGATTTACTCCCT
AAACGTTGTTAGTGATGCCTTACGAGATGCCTTGGATCCAAAATTGCGAGGCACAACTGAGGTAGCGGAAGGGGATTCCC
AGTTTGAGGCCAAAGAAGCCGCGATTCAGAAGGCTTAG

Upstream 100 bases:

>100_bases
ATGACGATGTATATCACCATTACCTATGCCCTGTTTAACCTAATCACTGACTTACTTATTGCTGCGGTGGATCCGCGCGT
CAAACTAAATTGAGGACTCC

Downstream 100 bases:

>100_bases
CTGACGATGGCCCTATACCTGTGGAGTTCTAAGGGCCAGGGTGAGTACTGCAGTCGCGGCTAGGGCAGCAGCAGTCCGGA
TATGATTCCAGAAGGTCCAT

Product: oligopeptide transport system permease AppC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTRVHNLYWEAAQKLSRQKLVVICLGIIAIYILVAVLGGFNVLPDYQTRVGAEYEAPSLELAKLLGTDLFGRSVLYKILA
GTKTAMLIGVLVTSISVPIGVILGALAGYYGGLVDVGIVWLYTVISSVPYILMVIAISYVIGKGLVAICLAMGLLGWVGL
CRLIRSEVLKTRNLEYVAAARVIGANDLQIIFSHILPNVIHLAIISASLQILGAIKSEVILTYIGVGIQDGASWGAMISD
ATGELVQGIWWPLAGVVLAMFLLIYSLNVVSDALRDALDPKLRGTTEVAEGDSQFEAKEAAIQKA

Sequences:

>Translated_305_residues
MTRVHNLYWEAAQKLSRQKLVVICLGIIAIYILVAVLGGFNVLPDYQTRVGAEYEAPSLELAKLLGTDLFGRSVLYKILA
GTKTAMLIGVLVTSISVPIGVILGALAGYYGGLVDVGIVWLYTVISSVPYILMVIAISYVIGKGLVAICLAMGLLGWVGL
CRLIRSEVLKTRNLEYVAAARVIGANDLQIIFSHILPNVIHLAIISASLQILGAIKSEVILTYIGVGIQDGASWGAMISD
ATGELVQGIWWPLAGVVLAMFLLIYSLNVVSDALRDALDPKLRGTTEVAEGDSQFEAKEAAIQKA
>Mature_304_residues
TRVHNLYWEAAQKLSRQKLVVICLGIIAIYILVAVLGGFNVLPDYQTRVGAEYEAPSLELAKLLGTDLFGRSVLYKILAG
TKTAMLIGVLVTSISVPIGVILGALAGYYGGLVDVGIVWLYTVISSVPYILMVIAISYVIGKGLVAICLAMGLLGWVGLC
RLIRSEVLKTRNLEYVAAARVIGANDLQIIFSHILPNVIHLAIISASLQILGAIKSEVILTYIGVGIQDGASWGAMISDA
TGELVQGIWWPLAGVVLAMFLLIYSLNVVSDALRDALDPKLRGTTEVAEGDSQFEAKEAAIQKA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:
GO:0005215: Oligopeptide transport system permease protein AppC, putative
GO:0005886: Oligopeptide transport system permease protein AppC, putative
GO:0006810: Oligopeptide transport system permease protein AppC, putative
GO:0016020: Oligopeptide transport system permease protein AppC, putative
GO:0016021: Oligopeptide transport system permease protein AppC, putative

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=289, Percent_Identity=30.1038062283737, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787498, Length=286, Percent_Identity=30.0699300699301, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789964, Length=225, Percent_Identity=37.3333333333333, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787760, Length=227, Percent_Identity=33.4801762114537, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=32.6086956521739, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=30.2904564315353, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787549, Length=266, Percent_Identity=28.1954887218045, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32626; Mature: 32495

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVHNLYWEAAQKLSRQKLVVICLGIIAIYILVAVLGGFNVLPDYQTRVGAEYEAPSLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHH
LAKLLGTDLFGRSVLYKILAGTKTAMLIGVLVTSISVPIGVILGALAGYYGGLVDVGIVW
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTVISSVPYILMVIAISYVIGKGLVAICLAMGLLGWVGLCRLIRSEVLKTRNLEYVAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVIGANDLQIIFSHILPNVIHLAIISASLQILGAIKSEVILTYIGVGIQDGASWGAMISD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ATGELVQGIWWPLAGVVLAMFLLIYSLNVVSDALRDALDPKLRGTTEVAEGDSQFEAKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHH
AIQKA
HHCCC
>Mature Secondary Structure 
TRVHNLYWEAAQKLSRQKLVVICLGIIAIYILVAVLGGFNVLPDYQTRVGAEYEAPSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHH
LAKLLGTDLFGRSVLYKILAGTKTAMLIGVLVTSISVPIGVILGALAGYYGGLVDVGIVW
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTVISSVPYILMVIAISYVIGKGLVAICLAMGLLGWVGLCRLIRSEVLKTRNLEYVAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVIGANDLQIIFSHILPNVIHLAIISASLQILGAIKSEVILTYIGVGIQDGASWGAMISD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ATGELVQGIWWPLAGVVLAMFLLIYSLNVVSDALRDALDPKLRGTTEVAEGDSQFEAKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHH
AIQKA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]