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The map label for this gene is petH [H]

Identifier: 158335202

GI number: 158335202

Start: 2038699

End: 2039748

Strand: Reverse

Name: petH [H]

Synonym: AM1_2045

Alternate gene names: 158335202

Gene position: 2039748-2038699 (Counterclockwise)

Preceding gene: 158335204

Following gene: 158335200

Centisome position: 31.36

GC content: 47.43

Gene sequence:

>1050_bases
ATGGAAAAACCGTTCGATCGATTGAAAAAGGATTTGAGAAATTTTGCCAAAGCTGGCGCCAAAATGGTCAACATTGACGT
TCCCGAGGTTGAAGAAAAGCCCATCATCGCAGAACCAGCCCCCGAAGCGCCCGTTGCCCCCCCTCAGTCCGCTAAAAAGG
CTAAGAAAAAAGACGATATTCCCGTTAATATATACCGTCCTAAAACCCCCTTTGTAGGGAAGTGCTTATCTAATGAAGCC
CTAGTGCGGGAAGGAGGCGAAGGGAGAGTTCAGCACCTTATGTTTGATCTTTCCGAAGGGGATCTCCGCTATATCGAAGG
TCAAAGTATTGGCATTATCCCTGCTGGAACAGATGCCAATGGTAAACCCCATAAGTTGCGTCTCTATTCCATTGCCTCGA
CTCGTCATGGCGATCGGGTAGATGATAAAACGATTTCTCTTTGTGTTCGCCAATTGGAATATGACCATCCTGAGACCGGA
GAGCGGGTCTATGGCGTGTGTTCCAAGCATCTATGCGACATGCAACCCGGTGATGATGTCAAAATTACGGGGCCAGTGGG
TAAAGAAATGCTGTTACCCGATGATCCTGAAGCCAACATCATCATGATGGGGACAGGCACTGGTATCGCTCCTTTCCGCG
CTTATCTGTGGCGGATGTTCAAAGAAAAGCATGACGACTATAAGTTCAAAGGCTTAGCCTGGCTATTCTTTGGGGTCGCT
TACACTCCCAATATCCTTTACAAGGAAGAGTTAGAAGAGCTACAGAGTCAATATCCTGATAACTTCCGGTTGACCTATGC
CATTAGCCGTGAGCAAAAGGCCGCAGATGGTAGCAAGATGTATATCCAAAGCCGTATTGCTGAACATGCCGATGAATTGT
GGGAGTTGGTTCAGAAAGAAAATACCCACACCTATATTTGCGGTTTGAAAGGTATGGAAGGTGGCATTGATGAAGGAATG
TCTGCTGCCGCTGCTAAGCATGGCGTGGATTGGTCCGAGTATCAGCGAACCTTGAAGAAGGCTCATCGCTGGCATGTAGA
AACCTACTAA

Upstream 100 bases:

>100_bases
AAACCGAAACCCTAAGAAGTGTAAGATACACTCCTTTGAAATCATAGACATTCTATTGCAAAATATTACGACAGGTTAGC
TTCGGAGAGCTTCAGAAATA

Downstream 100 bases:

>100_bases
ATCAACAACTTCAGTCAGCCATCAAAAAGGAGCCTCCCATATGGGAGGCTCCTTTTTGGTTGTTAGAGTTAGAGAAAATT
AGCTAATGCAGCTGTTTCTA

Product: ferredoxin-NADP reductase PetH

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MEKPFDRLKKDLRNFAKAGAKMVNIDVPEVEEKPIIAEPAPEAPVAPPQSAKKAKKKDDIPVNIYRPKTPFVGKCLSNEA
LVREGGEGRVQHLMFDLSEGDLRYIEGQSIGIIPAGTDANGKPHKLRLYSIASTRHGDRVDDKTISLCVRQLEYDHPETG
ERVYGVCSKHLCDMQPGDDVKITGPVGKEMLLPDDPEANIIMMGTGTGIAPFRAYLWRMFKEKHDDYKFKGLAWLFFGVA
YTPNILYKEELEELQSQYPDNFRLTYAISREQKAADGSKMYIQSRIAEHADELWELVQKENTHTYICGLKGMEGGIDEGM
SAAAAKHGVDWSEYQRTLKKAHRWHVETY

Sequences:

>Translated_349_residues
MEKPFDRLKKDLRNFAKAGAKMVNIDVPEVEEKPIIAEPAPEAPVAPPQSAKKAKKKDDIPVNIYRPKTPFVGKCLSNEA
LVREGGEGRVQHLMFDLSEGDLRYIEGQSIGIIPAGTDANGKPHKLRLYSIASTRHGDRVDDKTISLCVRQLEYDHPETG
ERVYGVCSKHLCDMQPGDDVKITGPVGKEMLLPDDPEANIIMMGTGTGIAPFRAYLWRMFKEKHDDYKFKGLAWLFFGVA
YTPNILYKEELEELQSQYPDNFRLTYAISREQKAADGSKMYIQSRIAEHADELWELVQKENTHTYICGLKGMEGGIDEGM
SAAAAKHGVDWSEYQRTLKKAHRWHVETY
>Mature_349_residues
MEKPFDRLKKDLRNFAKAGAKMVNIDVPEVEEKPIIAEPAPEAPVAPPQSAKKAKKKDDIPVNIYRPKTPFVGKCLSNEA
LVREGGEGRVQHLMFDLSEGDLRYIEGQSIGIIPAGTDANGKPHKLRLYSIASTRHGDRVDDKTISLCVRQLEYDHPETG
ERVYGVCSKHLCDMQPGDDVKITGPVGKEMLLPDDPEANIIMMGTGTGIAPFRAYLWRMFKEKHDDYKFKGLAWLFFGVA
YTPNILYKEELEELQSQYPDNFRLTYAISREQKAADGSKMYIQSRIAEHADELWELVQKENTHTYICGLKGMEGGIDEGM
SAAAAKHGVDWSEYQRTLKKAHRWHVETY

Specific function: Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Compo

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:
GO:0004324: Ferredoxin-NADP reductase PetH
GO:0016491: Ferredoxin-NADP reductase PetH
GO:0042651: Ferredoxin-NADP reductase PetH
GO:0050660: Ferredoxin-NADP reductase PetH
GO:0050661: Ferredoxin-NADP reductase PetH
GO:0055114: Ferredoxin-NADP reductase PetH

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI221316705, Length=243, Percent_Identity=28.3950617283951, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657393, Length=238, Percent_Identity=28.1512605042017, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221316709, Length=198, Percent_Identity=28.2828282828283, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI169790958, Length=165, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI169790956, Length=165, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40254422, Length=209, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24041029, Length=234, Percent_Identity=27.3504273504274, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789123, Length=204, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554134, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321143, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=135, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322699, Length=147, Percent_Identity=29.9319727891156, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI78706872, Length=239, Percent_Identity=33.0543933054393, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583543, Length=239, Percent_Identity=33.0543933054393, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78706876, Length=239, Percent_Identity=33.0543933054393, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17137192, Length=187, Percent_Identity=34.2245989304813, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24582192, Length=187, Percent_Identity=34.2245989304813, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012146
- InterPro:   IPR015701
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR008213
- InterPro:   IPR017938 [H]

Pfam domain/function: PF01383 CpcD; PF00667 FAD_binding_1; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 39444; Mature: 39444

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPFDRLKKDLRNFAKAGAKMVNIDVPEVEEKPIIAEPAPEAPVAPPQSAKKAKKKDDI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCC
PVNIYRPKTPFVGKCLSNEALVREGGEGRVQHLMFDLSEGDLRYIEGQSIGIIPAGTDAN
CEEEECCCCCHHHHHHCCCHHHHCCCCCCEEHHEEECCCCCEEEECCCEEEEEECCCCCC
GKPHKLRLYSIASTRHGDRVDDKTISLCVRQLEYDHPETGERVYGVCSKHLCDMQPGDDV
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCE
KITGPVGKEMLLPDDPEANIIMMGTGTGIAPFRAYLWRMFKEKHDDYKFKGLAWLFFGVA
EEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YTPNILYKEELEELQSQYPDNFRLTYAISREQKAADGSKMYIQSRIAEHADELWELVQKE
HCCCCEEHHHHHHHHHHCCCCEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
NTHTYICGLKGMEGGIDEGMSAAAAKHGVDWSEYQRTLKKAHRWHVETY
CCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEKPFDRLKKDLRNFAKAGAKMVNIDVPEVEEKPIIAEPAPEAPVAPPQSAKKAKKKDDI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCC
PVNIYRPKTPFVGKCLSNEALVREGGEGRVQHLMFDLSEGDLRYIEGQSIGIIPAGTDAN
CEEEECCCCCHHHHHHCCCHHHHCCCCCCEEHHEEECCCCCEEEECCCEEEEEECCCCCC
GKPHKLRLYSIASTRHGDRVDDKTISLCVRQLEYDHPETGERVYGVCSKHLCDMQPGDDV
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCE
KITGPVGKEMLLPDDPEANIIMMGTGTGIAPFRAYLWRMFKEKHDDYKFKGLAWLFFGVA
EEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YTPNILYKEELEELQSQYPDNFRLTYAISREQKAADGSKMYIQSRIAEHADELWELVQKE
HCCCCEEHHHHHHHHHHCCCCEEEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
NTHTYICGLKGMEGGIDEGMSAAAAKHGVDWSEYQRTLKKAHRWHVETY
CCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]