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The map label for this gene is murQ [H]

Identifier: 158335174

GI number: 158335174

Start: 2005450

End: 2006379

Strand: Direct

Name: murQ [H]

Synonym: AM1_2017

Alternate gene names: 158335174

Gene position: 2005450-2006379 (Clockwise)

Preceding gene: 158335173

Following gene: 158335176

Centisome position: 30.84

GC content: 51.72

Gene sequence:

>930_bases
TTGACTTCTACTCCTCAGCCTTTAAGCCAACGTGGACATCTTCTCACCGAACAGATTAATCCCAACAGCCAAAATCTCGA
TCAGTTGACGGCATTAGAGCTAGTCGATCTATTCAATCAGGAAGATCAGCAACTGATCAGCGCCATTGCCGCTGCTCGGG
AACCCTTGGCAGCAGCAGTCGAGAAAACGGCTCAAGCCTTGAGACAAGGTGGACGGTTATTTTATGTCGGGGCTGGAACC
AGTGGTCGTTTAGGGGTCTTAGATGCAGCCGAATGTCCCCCTACTTTTTGTACACCACCTGAAATGGTCCAGGGCATCTT
GGCAGGGGGAGAAGCTGCCTTAGTCAGAAGTTCAGAAGCGTTAGAAGATCGGGCCGATGATGGTGCGGCTGCCATTGCAA
ATCGAAACGTTTCCCCAACTGATGTGGTGGTGGGCATTACGGCAGGTGGAACGACTCCCTTTGTCCATGGTGCCTTGCAA
GCCGCCAATGAGCGAGGAGCAACCACTGTTTTTATGGCCTGCGTTCCTGCCGAACAGTTTTCCATCAATGTCGATATCGA
TGTGCGGCTACTCGTAGGACCCGAAATTTTAGCGGGCTCCACCCGCCTTAAAGCCGGGAGTGTCACCAAGTTAGCCCTAA
ATATTATCTCCACGGGGGCGATGGTCCAAATTGGTAAGGTGTATGGCAATCGGATGGTGGATGTCTCGGTCACAAACAGC
AAGTTAGAAGATCGAGCCCTGCGAATTATTGCTGATCTGACGGAGCTATCCCGAGACCAGGCAGCTGAGTTGTTAGGGAG
ATGCGATCGCAAAGTGAAACTAGCCCTACTTGTCCATTGGACAGGCCTCTCTACCGATCAGGGCCAAGCTCTGCTAGACC
AACATCAAGGCAATCTACGGCAAGCGGTTCAAAGCCAATCTGCACCTTAA

Upstream 100 bases:

>100_bases
CTTAGATTTATCCACGATTTTCTAACGCATCTTTCAGGATATGCCTTCTAGGGGTAGAGTCGAGAGGACCGCTTAAGTAT
GACGATCTCAGGTAATTCCC

Downstream 100 bases:

>100_bases
ATGTTATGAATCGGCTTCACAACCAGGGACGACTAGCTTCTTCTAAAGCAGTCACCTCTTCAGGCGTTAAGGACCATCCC
AAAGTCCCCGCATTTTCTAT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTSTPQPLSQRGHLLTEQINPNSQNLDQLTALELVDLFNQEDQQLISAIAAAREPLAAAVEKTAQALRQGGRLFYVGAGT
SGRLGVLDAAECPPTFCTPPEMVQGILAGGEAALVRSSEALEDRADDGAAAIANRNVSPTDVVVGITAGGTTPFVHGALQ
AANERGATTVFMACVPAEQFSINVDIDVRLLVGPEILAGSTRLKAGSVTKLALNIISTGAMVQIGKVYGNRMVDVSVTNS
KLEDRALRIIADLTELSRDQAAELLGRCDRKVKLALLVHWTGLSTDQGQALLDQHQGNLRQAVQSQSAP

Sequences:

>Translated_309_residues
MTSTPQPLSQRGHLLTEQINPNSQNLDQLTALELVDLFNQEDQQLISAIAAAREPLAAAVEKTAQALRQGGRLFYVGAGT
SGRLGVLDAAECPPTFCTPPEMVQGILAGGEAALVRSSEALEDRADDGAAAIANRNVSPTDVVVGITAGGTTPFVHGALQ
AANERGATTVFMACVPAEQFSINVDIDVRLLVGPEILAGSTRLKAGSVTKLALNIISTGAMVQIGKVYGNRMVDVSVTNS
KLEDRALRIIADLTELSRDQAAELLGRCDRKVKLALLVHWTGLSTDQGQALLDQHQGNLRQAVQSQSAP
>Mature_308_residues
TSTPQPLSQRGHLLTEQINPNSQNLDQLTALELVDLFNQEDQQLISAIAAAREPLAAAVEKTAQALRQGGRLFYVGAGTS
GRLGVLDAAECPPTFCTPPEMVQGILAGGEAALVRSSEALEDRADDGAAAIANRNVSPTDVVVGITAGGTTPFVHGALQA
ANERGATTVFMACVPAEQFSINVDIDVRLLVGPEILAGSTRLKAGSVTKLALNIISTGAMVQIGKVYGNRMVDVSVTNSK
LEDRALRIIADLTELSRDQAAELLGRCDRKVKLALLVHWTGLSTDQGQALLDQHQGNLRQAVQSQSAP

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=297, Percent_Identity=40.0673400673401, Blast_Score=227, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32550; Mature: 32419

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPQPLSQRGHLLTEQINPNSQNLDQLTALELVDLFNQEDQQLISAIAAAREPLAAAV
CCCCCCCHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EKTAQALRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPEMVQGILAGGEAALVRSSEA
HHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEECHHH
LEDRADDGAAAIANRNVSPTDVVVGITAGGTTPFVHGALQAANERGATTVFMACVPAEQF
HHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCE
SINVDIDVRLLVGPEILAGSTRLKAGSVTKLALNIISTGAMVQIGKVYGNRMVDVSVTNS
EEEECEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCEEEEEEECCC
KLEDRALRIIADLTELSRDQAAELLGRCDRKVKLALLVHWTGLSTDQGQALLDQHQGNLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHCCHHH
QAVQSQSAP
HHHHHCCCC
>Mature Secondary Structure 
TSTPQPLSQRGHLLTEQINPNSQNLDQLTALELVDLFNQEDQQLISAIAAAREPLAAAV
CCCCCCHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EKTAQALRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPEMVQGILAGGEAALVRSSEA
HHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEECHHH
LEDRADDGAAAIANRNVSPTDVVVGITAGGTTPFVHGALQAANERGATTVFMACVPAEQF
HHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCE
SINVDIDVRLLVGPEILAGSTRLKAGSVTKLALNIISTGAMVQIGKVYGNRMVDVSVTNS
EEEECEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCEEEEEEECCC
KLEDRALRIIADLTELSRDQAAELLGRCDRKVKLALLVHWTGLSTDQGQALLDQHQGNLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHCCHHH
QAVQSQSAP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA