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The map label for this gene is appC [H]

Identifier: 158335145

GI number: 158335145

Start: 1980592

End: 1981782

Strand: Reverse

Name: appC [H]

Synonym: AM1_1985

Alternate gene names: 158335145

Gene position: 1981782-1980592 (Counterclockwise)

Preceding gene: 158335146

Following gene: 158335141

Centisome position: 30.47

GC content: 51.72

Gene sequence:

>1191_bases
ATGAGTTGGTGGCAGCAGCTTCGTCAGAAAAAATTGGCTCGATTTGGGGCCGCTATTCTGATTACCTTCTACCTGTTAGT
GATCGGAGCAGACTTTGTTGCCCCCTATGCTCCTTGCGATACAGAAACCATTAATACTGGGGCCTGCCAGCCCCAAGTCA
ATGGCGCTTTATTACCGCCGACCCAGATTTATTGGAACAACGCTGATGGGCAATGGATTGGCCCCCATGTCTATCCCACC
ACCCTTGAACCCATTGACTGGCGCAACAAGGAATCCAAAGCCTGGCAAACCGGCATCCGTGATTTACAAGTCGATCGGAC
CCAACCGTCTCCCATTCGCCTGTTTGTCAAAGGCTGGAACTATCAGTTTTTGCAGCTAAAGCTCCCCCTACCGACTCAAT
GGTCTTGGTCCGACCCCAAAATCGATCAGGTCACGGTATTTCCAGGGTTTGCCTTTAACCGTCACTTGTTTGGCACCACT
GGCCCAGGCTATCTCAACGTCCTTGGTACGGATGACCAGGCTCGTGATCAACTCAGCCGAATCCTCTTTGGCGGCCGGAT
TAGCCTCAGTATTGGCTTAGTAGGGGTCGCTATTTCCCTCCCGTTAGGGATGCTGGTTGGTGGTATCTCTGGCTATTTCG
GTGGCTGGGTGGATAGCATTTTGATGCGTCTAGTGGAAGTCTTAATGACCATTCCTGGCCTGTATTTACTGGTGGCCCTG
GCCGCTATTTTGCCACCAGGATTGTCCAGTAGTGAGCGCTTTTTGTTAATTGTCTTAATTACCTCATTTGTGGGCTGGGC
AGGGCTAGCTCGGGTGATTCGCGGTCAGGTCCTGTCGATTAAGGAGCAGGAGTTTATCCAAGCGGCCAAGGTGATGGGAG
CTAGGCCCTTGTATATCATTACCCGCCATGTTCTCCCCCAAACTGCCACCTACGTGATTATTTCGGCTACCCTGGCTATT
CCCAGTTTTATCGTGGCGGAATCGGTATTAAGCCTGATTGGCCTGGGCATTGAACAGCCTGATCCCTCCTGGGGCAATTT
GCTGTCCCTATCGACCAATGCCTCCATTTTGATTTTGCAGCCCTGGTTGGTGTGGCCCCCCGCTATTTTGATTATCTTGA
CGGTGTTGTCCTTTAACCTCTTGGGGGACACCCTACGAGATATCTTGGACCCTAGAGGGTCACTCCAGTAG

Upstream 100 bases:

>100_bases
ACAACATGGGGTCAACCTCGTCTGTGCCCCCTTGCTTGGCATGGTTTAATCATGCCAGGACCTACAATGTGGAAGTCTTC
AGCACCCAGGACGAGACATT

Downstream 100 bases:

>100_bases
GTCCGGCTGCCAACGATAGCGGCGCAGGTCCAGTTTCTCTTGGCTATTGAAGGTGATGCCTTCTTGCTCCAGCAAAATGC
GCTGTAGGTCATCGCTCCCC

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSWWQQLRQKKLARFGAAILITFYLLVIGADFVAPYAPCDTETINTGACQPQVNGALLPPTQIYWNNADGQWIGPHVYPT
TLEPIDWRNKESKAWQTGIRDLQVDRTQPSPIRLFVKGWNYQFLQLKLPLPTQWSWSDPKIDQVTVFPGFAFNRHLFGTT
GPGYLNVLGTDDQARDQLSRILFGGRISLSIGLVGVAISLPLGMLVGGISGYFGGWVDSILMRLVEVLMTIPGLYLLVAL
AAILPPGLSSSERFLLIVLITSFVGWAGLARVIRGQVLSIKEQEFIQAAKVMGARPLYIITRHVLPQTATYVIISATLAI
PSFIVAESVLSLIGLGIEQPDPSWGNLLSLSTNASILILQPWLVWPPAILIILTVLSFNLLGDTLRDILDPRGSLQ

Sequences:

>Translated_396_residues
MSWWQQLRQKKLARFGAAILITFYLLVIGADFVAPYAPCDTETINTGACQPQVNGALLPPTQIYWNNADGQWIGPHVYPT
TLEPIDWRNKESKAWQTGIRDLQVDRTQPSPIRLFVKGWNYQFLQLKLPLPTQWSWSDPKIDQVTVFPGFAFNRHLFGTT
GPGYLNVLGTDDQARDQLSRILFGGRISLSIGLVGVAISLPLGMLVGGISGYFGGWVDSILMRLVEVLMTIPGLYLLVAL
AAILPPGLSSSERFLLIVLITSFVGWAGLARVIRGQVLSIKEQEFIQAAKVMGARPLYIITRHVLPQTATYVIISATLAI
PSFIVAESVLSLIGLGIEQPDPSWGNLLSLSTNASILILQPWLVWPPAILIILTVLSFNLLGDTLRDILDPRGSLQ
>Mature_395_residues
SWWQQLRQKKLARFGAAILITFYLLVIGADFVAPYAPCDTETINTGACQPQVNGALLPPTQIYWNNADGQWIGPHVYPTT
LEPIDWRNKESKAWQTGIRDLQVDRTQPSPIRLFVKGWNYQFLQLKLPLPTQWSWSDPKIDQVTVFPGFAFNRHLFGTTG
PGYLNVLGTDDQARDQLSRILFGGRISLSIGLVGVAISLPLGMLVGGISGYFGGWVDSILMRLVEVLMTIPGLYLLVALA
AILPPGLSSSERFLLIVLITSFVGWAGLARVIRGQVLSIKEQEFIQAAKVMGARPLYIITRHVLPQTATYVIISATLAIP
SFIVAESVLSLIGLGIEQPDPSWGNLLSLSTNASILILQPWLVWPPAILIILTVLSFNLLGDTLRDILDPRGSLQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=234, Percent_Identity=36.3247863247863, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787498, Length=298, Percent_Identity=35.2348993288591, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787760, Length=232, Percent_Identity=38.3620689655172, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789964, Length=235, Percent_Identity=36.1702127659575, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788505, Length=296, Percent_Identity=31.4189189189189, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789889, Length=231, Percent_Identity=30.3030303030303, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787549, Length=269, Percent_Identity=28.6245353159851, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43651; Mature: 43520

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWWQQLRQKKLARFGAAILITFYLLVIGADFVAPYAPCDTETINTGACQPQVNGALLPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQIYWNNADGQWIGPHVYPTTLEPIDWRNKESKAWQTGIRDLQVDRTQPSPIRLFVKGWN
CEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHCCHHEEECCCCCCCEEEEEECCC
YQFLQLKLPLPTQWSWSDPKIDQVTVFPGFAFNRHLFGTTGPGYLNVLGTDDQARDQLSR
EEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
ILFGGRISLSIGLVGVAISLPLGMLVGGISGYFGGWVDSILMRLVEVLMTIPGLYLLVAL
HHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAILPPGLSSSERFLLIVLITSFVGWAGLARVIRGQVLSIKEQEFIQAAKVMGARPLYII
HHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHCCCCHHHH
TRHVLPQTATYVIISATLAIPSFIVAESVLSLIGLGIEQPDPSWGNLLSLSTNASILILQ
HHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEE
PWLVWPPAILIILTVLSFNLLGDTLRDILDPRGSLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWWQQLRQKKLARFGAAILITFYLLVIGADFVAPYAPCDTETINTGACQPQVNGALLPP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQIYWNNADGQWIGPHVYPTTLEPIDWRNKESKAWQTGIRDLQVDRTQPSPIRLFVKGWN
CEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHCCHHEEECCCCCCCEEEEEECCC
YQFLQLKLPLPTQWSWSDPKIDQVTVFPGFAFNRHLFGTTGPGYLNVLGTDDQARDQLSR
EEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
ILFGGRISLSIGLVGVAISLPLGMLVGGISGYFGGWVDSILMRLVEVLMTIPGLYLLVAL
HHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAILPPGLSSSERFLLIVLITSFVGWAGLARVIRGQVLSIKEQEFIQAAKVMGARPLYII
HHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHCCCCHHHH
TRHVLPQTATYVIISATLAIPSFIVAESVLSLIGLGIEQPDPSWGNLLSLSTNASILILQ
HHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEE
PWLVWPPAILIILTVLSFNLLGDTLRDILDPRGSLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]