Click here to switch to the map view.

The map label for this gene is yycF [H]

Identifier: 158335119

GI number: 158335119

Start: 1954774

End: 1956561

Strand: Reverse

Name: yycF [H]

Synonym: AM1_1960

Alternate gene names: 158335119

Gene position: 1956561-1954774 (Counterclockwise)

Preceding gene: 158335120

Following gene: 158335113

Centisome position: 30.08

GC content: 49.5

Gene sequence:

>1788_bases
ATGCTCGGACGTCGCTTGAAGCGCCGAGGATATGATGTTGTGATTGCAGTTGATGGCGGTGAAGGCGTCACGAAGGCGCT
AACGGAACAGCCTGATCTGATTCTTATGGATATGAGCTTACCCGTGATGAATGGCTGGGAAGCGACGAGAACCCTCAAAG
CTGGAGACCAGACCGCCACTATTCCAATTATTGCCCTTACGGCCCATGCAATGGTGGGTGATCGAGAAGAGGCTCTAGCG
GCAGGGTGTGATGATTACGATACTAAACCTGTTGATCTGAAGCGGCTGTTGCAAAAAATTGAAACCCTATTGCAAAAGAC
TCAAGAACCATCAGCGCCATCACAACCTTTAGAAGCTGTGGCAAAAGCAACGCCAGCCCCTAACGCCGTTGCGACCCCCG
ATATTCCCCGTTCTGAGCAATTGGTCACCGCTACTGCTAGAACAGCTTCAGCAGATCAACAAGAAGTGAGTGGGGCGACT
CCCCTGGTTGCAGCTACACCCCGGCCCTCCTCTCCTCCCCCAACGTCTGCCCTTGAACCGACGACACCGACATTACTAGT
CGTGGATGATGTCGAGGCGAACCGGGATATGTTGAGTCGGCGTCTTCAGCGTAAAGGCTATGAAGTGGCGTTAGCAGACA
GTGGTGAAGCAGCCTTGGAACTGATGGCCACCACTGATATTGCTCTGGTCTTACTGGATATTATGATGCCAGGCATTGGG
GGGATTGAGACCCTGAAGCGTATTCGGCAGATCTATTCCCAGGAAGAGCTGCCGGTGATTATGGCAACAGCCAAAGATGC
CAGCGAAAATGTGGTCGAAGCCCTAGAACTAGGGGCCAATGATTACATTACGAAGCCCATTGATTTGCCCGTTGCCCTGG
CACGTATTCAAAGTCATCTCAAAACCCGTGAAGCCTCAGTCGCTGCCCGACAGCAGTTATTAGAATCGACCGTTACAGCG
GCTCCTCAACCCTCTTTTTGGGATGACCACTTTCGCTTGGTTGAAGTAATTAGCAAGCATGCCTTCGGACAAACGGTTAT
TGCCCAAGATCTGCAAGAACCGGATACTCCCCTGCGAATTGTTCATACCTTTCGACTAGACACCAATAATTCAGAGGTTT
TGCAGTCGGTTCAAGAGCTGTTTTTAGCTGAGATGACGACTTTGAAACAGCTAGCTCCCCATGTGCAATGTCTTCCGGTG
CTCAGCTTTTTACAGGATAGTGAAGTCCTGTATGTGGTGCATGAACATGTTGAAGGGGCCCTGCTGAGTAAAGTATTGGC
CTCCAAGGCTCCCTTAAATCCCCGCATGACCTGTAAGTTTGCAGATGAAGTCTTAACGATTGTTGAAATTCTGCATCAGG
CCGATCTGGTCCATAGTCATCCGCATCCCGATTGTTTTCTACAGCCCAATGAGAAAGGTAAAAAACTAGTCCTGATTGAC
TATGGGGTAGTCCCCCGTATTCTCAGTAAGCTTAGTCTTCAATATCCACAATATCAAAAACTGCTTCAGGATCAAGGCGA
TATTTTAGCCCCAGAAATTAGCTACGGTACCTTTAAACCTGAAACGGACCAATACGTGGTGGGCAAAATCTTTTTGCAAG
CCTTACAACTATCAGCACCAGGGGATGATCCAGAATTGGCTGAACTGCACCAGGCGACAGCTCAGATTTTCGCTCAGATG
TGCCACTTTAATATCCAAGCACGGTATTCGACGATGTACGATGCCAACCGGGCTGTCCGCAGCCACTGGCACAAACTCTG
GAAGGCTGAACTTTCTAAAAAGCTATAG

Upstream 100 bases:

>100_bases
CAGTTAATCTAGCCAGCGATTCACACACCTCAGGGATTAGAGAGGCCATCATTACATGCCGAAGATTCTTTTAGTTGAAG
ATAATGAACTTAACCGCGAC

Downstream 100 bases:

>100_bases
CTTAAAGTAGCCCCGCTAAATGCAGGGGACCATAACCGCTGATCAGTTCAACCAGTAATGCAATAAAGCCGACCATCGCA
AAGCGACCATTCCAGCGCTC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLGRRLKRRGYDVVIAVDGGEGVTKALTEQPDLILMDMSLPVMNGWEATRTLKAGDQTATIPIIALTAHAMVGDREEALA
AGCDDYDTKPVDLKRLLQKIETLLQKTQEPSAPSQPLEAVAKATPAPNAVATPDIPRSEQLVTATARTASADQQEVSGAT
PLVAATPRPSSPPPTSALEPTTPTLLVVDDVEANRDMLSRRLQRKGYEVALADSGEAALELMATTDIALVLLDIMMPGIG
GIETLKRIRQIYSQEELPVIMATAKDASENVVEALELGANDYITKPIDLPVALARIQSHLKTREASVAARQQLLESTVTA
APQPSFWDDHFRLVEVISKHAFGQTVIAQDLQEPDTPLRIVHTFRLDTNNSEVLQSVQELFLAEMTTLKQLAPHVQCLPV
LSFLQDSEVLYVVHEHVEGALLSKVLASKAPLNPRMTCKFADEVLTIVEILHQADLVHSHPHPDCFLQPNEKGKKLVLID
YGVVPRILSKLSLQYPQYQKLLQDQGDILAPEISYGTFKPETDQYVVGKIFLQALQLSAPGDDPELAELHQATAQIFAQM
CHFNIQARYSTMYDANRAVRSHWHKLWKAELSKKL

Sequences:

>Translated_595_residues
MLGRRLKRRGYDVVIAVDGGEGVTKALTEQPDLILMDMSLPVMNGWEATRTLKAGDQTATIPIIALTAHAMVGDREEALA
AGCDDYDTKPVDLKRLLQKIETLLQKTQEPSAPSQPLEAVAKATPAPNAVATPDIPRSEQLVTATARTASADQQEVSGAT
PLVAATPRPSSPPPTSALEPTTPTLLVVDDVEANRDMLSRRLQRKGYEVALADSGEAALELMATTDIALVLLDIMMPGIG
GIETLKRIRQIYSQEELPVIMATAKDASENVVEALELGANDYITKPIDLPVALARIQSHLKTREASVAARQQLLESTVTA
APQPSFWDDHFRLVEVISKHAFGQTVIAQDLQEPDTPLRIVHTFRLDTNNSEVLQSVQELFLAEMTTLKQLAPHVQCLPV
LSFLQDSEVLYVVHEHVEGALLSKVLASKAPLNPRMTCKFADEVLTIVEILHQADLVHSHPHPDCFLQPNEKGKKLVLID
YGVVPRILSKLSLQYPQYQKLLQDQGDILAPEISYGTFKPETDQYVVGKIFLQALQLSAPGDDPELAELHQATAQIFAQM
CHFNIQARYSTMYDANRAVRSHWHKLWKAELSKKL
>Mature_595_residues
MLGRRLKRRGYDVVIAVDGGEGVTKALTEQPDLILMDMSLPVMNGWEATRTLKAGDQTATIPIIALTAHAMVGDREEALA
AGCDDYDTKPVDLKRLLQKIETLLQKTQEPSAPSQPLEAVAKATPAPNAVATPDIPRSEQLVTATARTASADQQEVSGAT
PLVAATPRPSSPPPTSALEPTTPTLLVVDDVEANRDMLSRRLQRKGYEVALADSGEAALELMATTDIALVLLDIMMPGIG
GIETLKRIRQIYSQEELPVIMATAKDASENVVEALELGANDYITKPIDLPVALARIQSHLKTREASVAARQQLLESTVTA
APQPSFWDDHFRLVEVISKHAFGQTVIAQDLQEPDTPLRIVHTFRLDTNNSEVLQSVQELFLAEMTTLKQLAPHVQCLPV
LSFLQDSEVLYVVHEHVEGALLSKVLASKAPLNPRMTCKFADEVLTIVEILHQADLVHSHPHPDCFLQPNEKGKKLVLID
YGVVPRILSKLSLQYPQYQKLLQDQGDILAPEISYGTFKPETDQYVVGKIFLQALQLSAPGDDPELAELHQATAQIFAQM
CHFNIQARYSTMYDANRAVRSHWHKLWKAELSKKL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=166, Percent_Identity=31.3253012048193, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=33.0578512396694, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=42.8571428571429, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786599, Length=131, Percent_Identity=33.587786259542, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=35.8974358974359, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790437, Length=105, Percent_Identity=42.8571428571429, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=219, Percent_Identity=26.4840182648402, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=139, Percent_Identity=30.9352517985612, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=136, Percent_Identity=30.8823529411765, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=37.3831775700935, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=96, Percent_Identity=36.4583333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=156, Percent_Identity=31.4102564102564, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI2367329, Length=117, Percent_Identity=39.3162393162393, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788191, Length=103, Percent_Identity=35.9223300970874, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 65472; Mature: 65472

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRRLKRRGYDVVIAVDGGEGVTKALTEQPDLILMDMSLPVMNGWEATRTLKAGDQTAT
CCCCHHHHCCCEEEEEEECCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCE
IPIIALTAHAMVGDREEALAAGCDDYDTKPVDLKRLLQKIETLLQKTQEPSAPSQPLEAV
EEEEEEEHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AKATPAPNAVATPDIPRSEQLVTATARTASADQQEVSGATPLVAATPRPSSPPPTSALEP
HHCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCC
TTPTLLVVDDVEANRDMLSRRLQRKGYEVALADSGEAALELMATTDIALVLLDIMMPGIG
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
GIETLKRIRQIYSQEELPVIMATAKDASENVVEALELGANDYITKPIDLPVALARIQSHL
CHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KTREASVAARQQLLESTVTAAPQPSFWDDHFRLVEVISKHAFGQTVIAQDLQEPDTPLRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEE
VHTFRLDTNNSEVLQSVQELFLAEMTTLKQLAPHVQCLPVLSFLQDSEVLYVVHEHVEGA
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHH
LLSKVLASKAPLNPRMTCKFADEVLTIVEILHQADLVHSHPHPDCFLQPNEKGKKLVLID
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEEE
YGVVPRILSKLSLQYPQYQKLLQDQGDILAPEISYGTFKPETDQYVVGKIFLQALQLSAP
CCHHHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
GDDPELAELHQATAQIFAQMCHFNIQARYSTMYDANRAVRSHWHKLWKAELSKKL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGRRLKRRGYDVVIAVDGGEGVTKALTEQPDLILMDMSLPVMNGWEATRTLKAGDQTAT
CCCCHHHHCCCEEEEEEECCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCE
IPIIALTAHAMVGDREEALAAGCDDYDTKPVDLKRLLQKIETLLQKTQEPSAPSQPLEAV
EEEEEEEHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AKATPAPNAVATPDIPRSEQLVTATARTASADQQEVSGATPLVAATPRPSSPPPTSALEP
HHCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCC
TTPTLLVVDDVEANRDMLSRRLQRKGYEVALADSGEAALELMATTDIALVLLDIMMPGIG
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
GIETLKRIRQIYSQEELPVIMATAKDASENVVEALELGANDYITKPIDLPVALARIQSHL
CHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KTREASVAARQQLLESTVTAAPQPSFWDDHFRLVEVISKHAFGQTVIAQDLQEPDTPLRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEE
VHTFRLDTNNSEVLQSVQELFLAEMTTLKQLAPHVQCLPVLSFLQDSEVLYVVHEHVEGA
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHH
LLSKVLASKAPLNPRMTCKFADEVLTIVEILHQADLVHSHPHPDCFLQPNEKGKKLVLID
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEEE
YGVVPRILSKLSLQYPQYQKLLQDQGDILAPEISYGTFKPETDQYVVGKIFLQALQLSAP
CCHHHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
GDDPELAELHQATAQIFAQMCHFNIQARYSTMYDANRAVRSHWHKLWKAELSKKL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]