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The map label for this gene is lnt [H]

Identifier: 158334952

GI number: 158334952

Start: 1779832

End: 1781292

Strand: Reverse

Name: lnt [H]

Synonym: AM1_1789

Alternate gene names: 158334952

Gene position: 1781292-1779832 (Counterclockwise)

Preceding gene: 158334955

Following gene: 158334951

Centisome position: 27.39

GC content: 51.68

Gene sequence:

>1461_bases
ATGGGTATTATTCCCGCCCCCGTGGGGGCTTGGTGGTTCGCATGGATTGCTTTGGTCCCCCTGTGGATGTACGTTAACCG
TGCTCAGGGGCGGGTTTGGCTGGCGATGCGGCTAGGTTTCGCGTGGGGACTAGGGTATCAGGGGGCTGCAGTGTCGTGGG
TAACGGGCTTGCATCCGTTGACATGGATGGGGCTGTCTTGGTGGGCAAGTCTGACGATTGCGTTGGCTTGCTGGATGTTT
GTAACGGTTTATGGGGCGTTGATTGCTGCTTTATGGTCTGGGTGGATGGCCTGGATAGGGGCAAAAATCCCTGTTTACCA
CCGAATTTTGGTGGGAACAACGGCTTGGATGGTCTTGGAGTGGCTCTGGACTCAATCGCCCTTGTGGTGGACGCCGATTT
CTTATACTCAAAGCCCGGCGAATCTGATCATCCTGCATTTGGGGCGGATATCCGGCCCGACCGTTATTGTGGCTGCATTA
GTCATGGTTAATGGCTGTTTAGCAGAAAGCTGGATAGCCCTTCGTGATCGGTGGCGGTATCGCAGTGTTGCGATCGCACT
TTTTATCGGTTTACATCTATTAGGCTTGAGCCTGTACCTGCAGCCATTGCAGATGGAGCAGGACACCGCCCTTAACATCG
GCATTATTCAAGGTAATATCCCAACGCGGATCAAATTATTTAAGCAAGGTCTTGAACTGGGGCGTCAGAATTATGAGGCG
GGCTATCGGCAGTTGGCCGATCAAGGCGTTGATGCAGTACTCACACCAGAAGGGGCGTTTCCCTTTCTATGGCGAGACCA
GCCCCCCTTAGTTAAGGCCATTCAAGATAAACAGGTGGTGGCCTGGCTTGGGAGTTTTATGCCCGAAGACCATCGCATCA
CTCAGAGTTTAATTACCGTTTTGGCCGATGGCAGCATCTTTAGCCGCTATAACAAAATTAAGCTGGTGCCCCTAGGTGAA
TATATTCCCTTTGAATCCATTTTGGGTAGGTTAATCGGTCGGTTGACCCCCGTGAGTACCCAGATGAATTTAGGGAAGCC
TGATCAACAATTCTTGACCCCTTGGGGACCTGCGATCGCAGGGATTTGTTTTGATTCCGCCTTTCCGCAACTGTTTCAAA
AGCAAGCCGCTCAAGGCGGAGAGTTTGTTCTGACGGCCTCCAATAACGATCCTTACAATGCTCGGATGATGGCTCAGCAC
CATGCCCATGACGTCATGAGAGCGATAGAAACCGATCGGTGGACCGTTCGTTCGACGAACACTGGTTACTCTGGTGTGAT
TAACCCCCATGGCCAAACCTTGTGGCGCTCACAGCCTCTGGTGTTTGCTACCCATGCTGCCACCATTTACCGCCGTCAAA
CTCAGACTTTATATGTACAGTGGGGAAATTGGTTCTTACCTAGCTTGGTGGCACTCAGTATGATTGCGGGCTTTCCCTCT
TTCATCAACACCAGTAAGTAA

Upstream 100 bases:

>100_bases
CAGAATATACGTGAAATATATTGTTCAAGATCGTATTCGACCGAAAATCTCTACGGCTAAATGGCGAGGGTTTGGTATCG
TTTTTCTCTCGGGCTTAGGG

Downstream 100 bases:

>100_bases
GCTAAGTTAGATAAAACTGGCTTTTCAACTGAGGTATGGCAGCATCATTTGCCATTTCCCTAGGGTACGCTCTCTATCTT
GAACACAACTCGATTTAATA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MGIIPAPVGAWWFAWIALVPLWMYVNRAQGRVWLAMRLGFAWGLGYQGAAVSWVTGLHPLTWMGLSWWASLTIALACWMF
VTVYGALIAALWSGWMAWIGAKIPVYHRILVGTTAWMVLEWLWTQSPLWWTPISYTQSPANLIILHLGRISGPTVIVAAL
VMVNGCLAESWIALRDRWRYRSVAIALFIGLHLLGLSLYLQPLQMEQDTALNIGIIQGNIPTRIKLFKQGLELGRQNYEA
GYRQLADQGVDAVLTPEGAFPFLWRDQPPLVKAIQDKQVVAWLGSFMPEDHRITQSLITVLADGSIFSRYNKIKLVPLGE
YIPFESILGRLIGRLTPVSTQMNLGKPDQQFLTPWGPAIAGICFDSAFPQLFQKQAAQGGEFVLTASNNDPYNARMMAQH
HAHDVMRAIETDRWTVRSTNTGYSGVINPHGQTLWRSQPLVFATHAATIYRRQTQTLYVQWGNWFLPSLVALSMIAGFPS
FINTSK

Sequences:

>Translated_486_residues
MGIIPAPVGAWWFAWIALVPLWMYVNRAQGRVWLAMRLGFAWGLGYQGAAVSWVTGLHPLTWMGLSWWASLTIALACWMF
VTVYGALIAALWSGWMAWIGAKIPVYHRILVGTTAWMVLEWLWTQSPLWWTPISYTQSPANLIILHLGRISGPTVIVAAL
VMVNGCLAESWIALRDRWRYRSVAIALFIGLHLLGLSLYLQPLQMEQDTALNIGIIQGNIPTRIKLFKQGLELGRQNYEA
GYRQLADQGVDAVLTPEGAFPFLWRDQPPLVKAIQDKQVVAWLGSFMPEDHRITQSLITVLADGSIFSRYNKIKLVPLGE
YIPFESILGRLIGRLTPVSTQMNLGKPDQQFLTPWGPAIAGICFDSAFPQLFQKQAAQGGEFVLTASNNDPYNARMMAQH
HAHDVMRAIETDRWTVRSTNTGYSGVINPHGQTLWRSQPLVFATHAATIYRRQTQTLYVQWGNWFLPSLVALSMIAGFPS
FINTSK
>Mature_485_residues
GIIPAPVGAWWFAWIALVPLWMYVNRAQGRVWLAMRLGFAWGLGYQGAAVSWVTGLHPLTWMGLSWWASLTIALACWMFV
TVYGALIAALWSGWMAWIGAKIPVYHRILVGTTAWMVLEWLWTQSPLWWTPISYTQSPANLIILHLGRISGPTVIVAALV
MVNGCLAESWIALRDRWRYRSVAIALFIGLHLLGLSLYLQPLQMEQDTALNIGIIQGNIPTRIKLFKQGLELGRQNYEAG
YRQLADQGVDAVLTPEGAFPFLWRDQPPLVKAIQDKQVVAWLGSFMPEDHRITQSLITVLADGSIFSRYNKIKLVPLGEY
IPFESILGRLIGRLTPVSTQMNLGKPDQQFLTPWGPAIAGICFDSAFPQLFQKQAAQGGEFVLTASNNDPYNARMMAQHH
AHDVMRAIETDRWTVRSTNTGYSGVINPHGQTLWRSQPLVFATHAATIYRRQTQTLYVQWGNWFLPSLVALSMIAGFPSF
INTSK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=489, Percent_Identity=26.3803680981595, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 54592; Mature: 54461

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIPAPVGAWWFAWIALVPLWMYVNRAQGRVWLAMRLGFAWGLGYQGAAVSWVTGLHPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHCCCHH
TWMGLSWWASLTIALACWMFVTVYGALIAALWSGWMAWIGAKIPVYHRILVGTTAWMVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WLWTQSPLWWTPISYTQSPANLIILHLGRISGPTVIVAALVMVNGCLAESWIALRDRWRY
HHHCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVAIALFIGLHLLGLSLYLQPLQMEQDTALNIGIIQGNIPTRIKLFKQGLELGRQNYEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GYRQLADQGVDAVLTPEGAFPFLWRDQPPLVKAIQDKQVVAWLGSFMPEDHRITQSLITV
HHHHHHHCCCCEEECCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
LADGSIFSRYNKIKLVPLGEYIPFESILGRLIGRLTPVSTQMNLGKPDQQFLTPWGPAIA
HCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHH
GICFDSAFPQLFQKQAAQGGEFVLTASNNDPYNARMMAQHHAHDVMRAIETDRWTVRSTN
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
TGYSGVINPHGQTLWRSQPLVFATHAATIYRRQTQTLYVQWGNWFLPSLVALSMIAGFPS
CCCCCEECCCCCHHHCCCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHH
FINTSK
HHCCCC
>Mature Secondary Structure 
GIIPAPVGAWWFAWIALVPLWMYVNRAQGRVWLAMRLGFAWGLGYQGAAVSWVTGLHPL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHCCCHH
TWMGLSWWASLTIALACWMFVTVYGALIAALWSGWMAWIGAKIPVYHRILVGTTAWMVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WLWTQSPLWWTPISYTQSPANLIILHLGRISGPTVIVAALVMVNGCLAESWIALRDRWRY
HHHCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVAIALFIGLHLLGLSLYLQPLQMEQDTALNIGIIQGNIPTRIKLFKQGLELGRQNYEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GYRQLADQGVDAVLTPEGAFPFLWRDQPPLVKAIQDKQVVAWLGSFMPEDHRITQSLITV
HHHHHHHCCCCEEECCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
LADGSIFSRYNKIKLVPLGEYIPFESILGRLIGRLTPVSTQMNLGKPDQQFLTPWGPAIA
HCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHH
GICFDSAFPQLFQKQAAQGGEFVLTASNNDPYNARMMAQHHAHDVMRAIETDRWTVRSTN
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
TGYSGVINPHGQTLWRSQPLVFATHAATIYRRQTQTLYVQWGNWFLPSLVALSMIAGFPS
CCCCCEECCCCCHHHCCCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHH
FINTSK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]