Click here to switch to the map view.

The map label for this gene is cyaD [H]

Identifier: 158334921

GI number: 158334921

Start: 1745049

End: 1746353

Strand: Direct

Name: cyaD [H]

Synonym: AM1_1758

Alternate gene names: 158334921

Gene position: 1745049-1746353 (Clockwise)

Preceding gene: 158334920

Following gene: 158334922

Centisome position: 26.83

GC content: 49.2

Gene sequence:

>1305_bases
ATGAATACCCTCCAACCTGATCAACTTCACTTTGTTCAGGAAGATGAATTTTTACCCTCCATTAGCCCGTGGATTTCAAT
GGGGGGAATGGTTTTGGTGCTGGTATTCGGTGCCGCTGTTGCCATTTCCTCTACCCTCAAATTCAGCATCACTGTCAAAG
CCCCTGCAGCCATTCGGCCCGCAGGTGGCCTGAGTATCGTCCAAAGTGGTATTGATGGCACCATTACTCATATCAACGTG
GAGGAAAACCAGGTCGTCAAAAAAGGCGATCTGTTTGCACAGCTAGACGATTCAGGGTTGCAAACCCGCAAAAGCCAACT
GCAAGGAGATATCCAATCCATTACCCTGCAGAGATATCAGATCAATGCTCAACTCAGAGCGTTAGACCATCAAATTATTG
CTGAAACCCGGTTAGTCAGCCGTTCCATCGCCGCCGCAGAAGCCAACTTAACCTCACACCGTCGTCGCTATCAAGATCTT
AAAATCAGTACCGAAGCAGACCTAGAAGAAGCCCAAGCTGGGTACCACCTGGCTTCTGAAGAGTATCTACGCTTCAAAGA
ACTCGAGGAATCAGGAGCCATTGCCAAACTGCAGGTCAAAGAGAAAGAAGCCTCTTTGAAAGCGGCATCCGCCAGAATTA
AGCGTCTTAAGGCTGCAACCAATCCATCAGACGCCACTATTGATCAAGCCTTAGAACAAATTGCCCAGGAAAAAGCCAGA
GGTAGTGTCACCCTGGCAGGTCTCAATCAACAAAAAGAACAGCTGATGCGCACCCGCATCGAAGCCCAAAAGCAGCTCCA
ACGCACTCAAAAAGAGCTACAGCAAATCGATAACGAACTCAAAGGTACTAAAATCCGGGCTCCCATCGATGGCACCGTTT
TACAGCTCAATCTACGCAATCCCGGTCAAGTGGTGCAGCCTGGAATCCCCATCGCTCAAATTGCCCCCCGCAACGCTCCT
TTGATTATCAAGGCTAGGGTCAACGCCCAAGATATCAACCAGGTGAAAACAGGGCAGATGGTTCAAATGCGCGTTTCAGC
CTGCCCCTACACGGATTACGGCACCTTACAGGGAACCGTTATGAATGTGTCACCGGATGCCATTCCGGTGAATGATGCTA
GCGGTCCAGCCACTAGTCCAGCTTTTTATGAAGTTACCGTACAACCTCGAACCTTATATATGGGCAATCAACAGCGCTGG
TGCCGCCTGCAATTTGGGATGGAGGGTCGAGCCGATATTGTGTCACGCCAAGAAACCGTTCTCCAATTTGTCTTGAAAAA
AGCCCGCTTAATGTCCAACTTCTAA

Upstream 100 bases:

>100_bases
TAGCTTCTCAAGGATTTAATTATAACAGGCATTAAAGATTAGCTAGTTTCTTGACCTAACCCCCTATCAATCTCCTTAAT
GCATAGCCCCATAAGATTCC

Downstream 100 bases:

>100_bases
CTCGCCTGATCAAACGATAAAGGCACCTTGTCCATGCCCTCTTTAATGCTCCTCAATCCCCTACTCAAATCACGCAAAAG
CTACCAGTGTGTCAAGCAAT

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNTLQPDQLHFVQEDEFLPSISPWISMGGMVLVLVFGAAVAISSTLKFSITVKAPAAIRPAGGLSIVQSGIDGTITHINV
EENQVVKKGDLFAQLDDSGLQTRKSQLQGDIQSITLQRYQINAQLRALDHQIIAETRLVSRSIAAAEANLTSHRRRYQDL
KISTEADLEEAQAGYHLASEEYLRFKELEESGAIAKLQVKEKEASLKAASARIKRLKAATNPSDATIDQALEQIAQEKAR
GSVTLAGLNQQKEQLMRTRIEAQKQLQRTQKELQQIDNELKGTKIRAPIDGTVLQLNLRNPGQVVQPGIPIAQIAPRNAP
LIIKARVNAQDINQVKTGQMVQMRVSACPYTDYGTLQGTVMNVSPDAIPVNDASGPATSPAFYEVTVQPRTLYMGNQQRW
CRLQFGMEGRADIVSRQETVLQFVLKKARLMSNF

Sequences:

>Translated_434_residues
MNTLQPDQLHFVQEDEFLPSISPWISMGGMVLVLVFGAAVAISSTLKFSITVKAPAAIRPAGGLSIVQSGIDGTITHINV
EENQVVKKGDLFAQLDDSGLQTRKSQLQGDIQSITLQRYQINAQLRALDHQIIAETRLVSRSIAAAEANLTSHRRRYQDL
KISTEADLEEAQAGYHLASEEYLRFKELEESGAIAKLQVKEKEASLKAASARIKRLKAATNPSDATIDQALEQIAQEKAR
GSVTLAGLNQQKEQLMRTRIEAQKQLQRTQKELQQIDNELKGTKIRAPIDGTVLQLNLRNPGQVVQPGIPIAQIAPRNAP
LIIKARVNAQDINQVKTGQMVQMRVSACPYTDYGTLQGTVMNVSPDAIPVNDASGPATSPAFYEVTVQPRTLYMGNQQRW
CRLQFGMEGRADIVSRQETVLQFVLKKARLMSNF
>Mature_434_residues
MNTLQPDQLHFVQEDEFLPSISPWISMGGMVLVLVFGAAVAISSTLKFSITVKAPAAIRPAGGLSIVQSGIDGTITHINV
EENQVVKKGDLFAQLDDSGLQTRKSQLQGDIQSITLQRYQINAQLRALDHQIIAETRLVSRSIAAAEANLTSHRRRYQDL
KISTEADLEEAQAGYHLASEEYLRFKELEESGAIAKLQVKEKEASLKAASARIKRLKAATNPSDATIDQALEQIAQEKAR
GSVTLAGLNQQKEQLMRTRIEAQKQLQRTQKELQQIDNELKGTKIRAPIDGTVLQLNLRNPGQVVQPGIPIAQIAPRNAP
LIIKARVNAQDINQVKTGQMVQMRVSACPYTDYGTLQGTVMNVSPDAIPVNDASGPATSPAFYEVTVQPRTLYMGNQQRW
CRLQFGMEGRADIVSRQETVLQFVLKKARLMSNF

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47888; Mature: 47888

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLQPDQLHFVQEDEFLPSISPWISMGGMVLVLVFGAAVAISSTLKFSITVKAPAAIRP
CCCCCCCCEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
AGGLSIVQSGIDGTITHINVEENQVVKKGDLFAQLDDSGLQTRKSQLQGDIQSITLQRYQ
CCCHHHHHCCCCCEEEEEECCCCCEEECCCEEEEECCCHHHHHHHHHCCCHHHHEEEEEE
INAQLRALDHQIIAETRLVSRSIAAAEANLTSHRRRYQDLKISTEADLEEAQAGYHLASE
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHCCCCCCHH
EYLRFKELEESGAIAKLQVKEKEASLKAASARIKRLKAATNPSDATIDQALEQIAQEKAR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GSVTLAGLNQQKEQLMRTRIEAQKQLQRTQKELQQIDNELKGTKIRAPIDGTVLQLNLRN
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECC
PGQVVQPGIPIAQIAPRNAPLIIKARVNAQDINQVKTGQMVQMRVSACPYTDYGTLQGTV
CCCCCCCCCCHHHCCCCCCCEEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEE
MNVSPDAIPVNDASGPATSPAFYEVTVQPRTLYMGNQQRWCRLQFGMEGRADIVSRQETV
EECCCCCEECCCCCCCCCCCEEEEEEECCEEEEECCCCCEEEEEECCCCCHHHHHHHHHH
LQFVLKKARLMSNF
HHHHHHHHHHHCCC
>Mature Secondary Structure
MNTLQPDQLHFVQEDEFLPSISPWISMGGMVLVLVFGAAVAISSTLKFSITVKAPAAIRP
CCCCCCCCEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
AGGLSIVQSGIDGTITHINVEENQVVKKGDLFAQLDDSGLQTRKSQLQGDIQSITLQRYQ
CCCHHHHHCCCCCEEEEEECCCCCEEECCCEEEEECCCHHHHHHHHHCCCHHHHEEEEEE
INAQLRALDHQIIAETRLVSRSIAAAEANLTSHRRRYQDLKISTEADLEEAQAGYHLASE
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHCCCCCCHH
EYLRFKELEESGAIAKLQVKEKEASLKAASARIKRLKAATNPSDATIDQALEQIAQEKAR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GSVTLAGLNQQKEQLMRTRIEAQKQLQRTQKELQQIDNELKGTKIRAPIDGTVLQLNLRN
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECC
PGQVVQPGIPIAQIAPRNAPLIIKARVNAQDINQVKTGQMVQMRVSACPYTDYGTLQGTV
CCCCCCCCCCHHHCCCCCCCEEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEE
MNVSPDAIPVNDASGPATSPAFYEVTVQPRTLYMGNQQRWCRLQFGMEGRADIVSRQETV
EECCCCCEECCCCCCCCCCCEEEEEEECCEEEEECCCCCEEEEEECCCCCHHHHHHHHHH
LQFVLKKARLMSNF
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]