Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 158334846

GI number: 158334846

Start: 1657692

End: 1659341

Strand: Reverse

Name: ubiB [C]

Synonym: AM1_1683

Alternate gene names: 158334846

Gene position: 1659341-1657692 (Counterclockwise)

Preceding gene: 158334848

Following gene: 158334839

Centisome position: 25.51

GC content: 51.88

Gene sequence:

>1650_bases
GTGTTCTCAGGGTTAACGCAAACAGCCTCCCGGCAACGCGACATTATTGAAGTGGTCCTCCGGAATGGCTGGGACTATAT
GCAGCAGCTGTTAACGGGCGGCAAAGCGGATCAGCCTGCTTTGCCGACGCCTGCGGTGCTGCGCAATATTTTGGTGGATT
TAGGGCCAGTCTATGTCAAGCTAGGCCAGCTTTTGAGTACGCGACCGGATATTTTGCCTGCCCCCTATATTGACGCTCTG
TCTACCCTTCAGAGCAAAGTGCCACCTGTGGCCTGGCCGGAAATCAAGGCGGTGATTCAGCAGCAGATTGCCCAGGAACT
GCGGTCTCAGTTCAAAGAAATTGACCCGACTCCCGTGGCCTCAGGATCCATTGCCCAAGTTCATCGAGCGATCCTGGCAA
ACGGACAGCAAGTGGCGATTAAGGTGCAGCGACCAGGGATTGATGTCATCGTCAATCAAGATATTGCACTGATCAATACC
CTCGCGGATTTGGCATCCCGAACGGATATTGGTAAAGATTACGACCTTAAGTCCTTGGCGGCAGAGTTTGCCAATGCCCT
TTTAGATGAACTGGATTTTACTGTTGAAGCCAGCCATACGGAGCAGCTTCGCCAAAATCTCTCCACCAGCCGCTGGTTTG
ATCCGCAGCAGCTCGTGGTCCCCAAAATCAATCTGGCCTTGACCACCCAGAAAGTGCTGGTGATGCAGTGGCTAGACGGA
GAGCCCTTGTTGTCGGCAAACCTGCCTTTTTCTCAACAGGAGCCCAGAATTGATAGTGCCCGTCGGCAAGTGACAACGCT
GTTATTTCGGGCCTTTTTGCAGCAAATCTATGTGGATGGCTTCTTCCATGCCGACCCTCATCCCGGCAATTTGTACTATC
TAAACGATGGCCGAGCCGCGATCTTAGACTGCGGTATGGTCGGACGCCTAGATCCCAATACCCAGCAGATTTTGACGGAG
ATGCTGTTAGCCATTGTGGATCTGGATGCCCAACGCTGTAGCCGTTTGACCTTACAGCTAGCGAAAACTCGACGGGCAGA
GAACCTGGCCCAGCTCGAAAGTGATTTTGAAGCCCTGCTGCGCAAGTACTATAATCGCAATCTGGCGGAAATTAATCTGG
GAGAAGTGCTGTACGAAGTACTGCAAGTGGCCCGTACCAATAAGCTGAAGCTACCGGGAAATGTGGGGCTATACGTCAAG
GCGTTAGCCAATTTAGAAGGAGCGGCTCGGACCTTTGACCCCAAGTTTAATGTGCTGGATGAAATTAAGCCGTTGATGAG
CGATTTATTTCGACGCCAGTTTGTCGGGGAAGATCCCTTGCCGACGCTGCTAAGGACGGCATTAGATGTGAAGAATTTGT
CCTTGAGATCGCCCCGGCAATTAGAGCAACTTCTAGACCAAGTGACGTCGGAATCCTTGCAGTGGAACTTAAATCTGTTG
GGTCTGAATGGCTTACGGATTACCGTCGATAACGCGGCCAATCGCCTGTCGTTCAGTATTTTGGTGGGGTCGCTGATTAT
GGGGGCAGCGATGATTTCGGCAGAGAAACAGACGGCCTTGTATTGGTTGAGCAATACCCTGTTTGCCGTGGCAAGCTTTT
TGGGACTGTGGTTAGCGGTTAGTATCTTGCGATCGGGGAATCTCCGCTGA

Upstream 100 bases:

>100_bases
CCCAGACTGTTGAGTCCAATGCAATGACCCCAGGGAGTTTTGAGCTAGGATCGCAACAGCAAGATGTTCGAACGGTTCAA
CTAACCTCAAAGGAGGCATT

Downstream 100 bases:

>100_bases
GTTGAATTTTTAGGTGTAACTTCGGAAAGGCTTTACTGTTCAACTACTCGACATCATCCCCTAGTTTGGTCAGGTCCTTG
GTCTGGACGATTTTTCTTTG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MFSGLTQTASRQRDIIEVVLRNGWDYMQQLLTGGKADQPALPTPAVLRNILVDLGPVYVKLGQLLSTRPDILPAPYIDAL
STLQSKVPPVAWPEIKAVIQQQIAQELRSQFKEIDPTPVASGSIAQVHRAILANGQQVAIKVQRPGIDVIVNQDIALINT
LADLASRTDIGKDYDLKSLAAEFANALLDELDFTVEASHTEQLRQNLSTSRWFDPQQLVVPKINLALTTQKVLVMQWLDG
EPLLSANLPFSQQEPRIDSARRQVTTLLFRAFLQQIYVDGFFHADPHPGNLYYLNDGRAAILDCGMVGRLDPNTQQILTE
MLLAIVDLDAQRCSRLTLQLAKTRRAENLAQLESDFEALLRKYYNRNLAEINLGEVLYEVLQVARTNKLKLPGNVGLYVK
ALANLEGAARTFDPKFNVLDEIKPLMSDLFRRQFVGEDPLPTLLRTALDVKNLSLRSPRQLEQLLDQVTSESLQWNLNLL
GLNGLRITVDNAANRLSFSILVGSLIMGAAMISAEKQTALYWLSNTLFAVASFLGLWLAVSILRSGNLR

Sequences:

>Translated_549_residues
MFSGLTQTASRQRDIIEVVLRNGWDYMQQLLTGGKADQPALPTPAVLRNILVDLGPVYVKLGQLLSTRPDILPAPYIDAL
STLQSKVPPVAWPEIKAVIQQQIAQELRSQFKEIDPTPVASGSIAQVHRAILANGQQVAIKVQRPGIDVIVNQDIALINT
LADLASRTDIGKDYDLKSLAAEFANALLDELDFTVEASHTEQLRQNLSTSRWFDPQQLVVPKINLALTTQKVLVMQWLDG
EPLLSANLPFSQQEPRIDSARRQVTTLLFRAFLQQIYVDGFFHADPHPGNLYYLNDGRAAILDCGMVGRLDPNTQQILTE
MLLAIVDLDAQRCSRLTLQLAKTRRAENLAQLESDFEALLRKYYNRNLAEINLGEVLYEVLQVARTNKLKLPGNVGLYVK
ALANLEGAARTFDPKFNVLDEIKPLMSDLFRRQFVGEDPLPTLLRTALDVKNLSLRSPRQLEQLLDQVTSESLQWNLNLL
GLNGLRITVDNAANRLSFSILVGSLIMGAAMISAEKQTALYWLSNTLFAVASFLGLWLAVSILRSGNLR
>Mature_549_residues
MFSGLTQTASRQRDIIEVVLRNGWDYMQQLLTGGKADQPALPTPAVLRNILVDLGPVYVKLGQLLSTRPDILPAPYIDAL
STLQSKVPPVAWPEIKAVIQQQIAQELRSQFKEIDPTPVASGSIAQVHRAILANGQQVAIKVQRPGIDVIVNQDIALINT
LADLASRTDIGKDYDLKSLAAEFANALLDELDFTVEASHTEQLRQNLSTSRWFDPQQLVVPKINLALTTQKVLVMQWLDG
EPLLSANLPFSQQEPRIDSARRQVTTLLFRAFLQQIYVDGFFHADPHPGNLYYLNDGRAAILDCGMVGRLDPNTQQILTE
MLLAIVDLDAQRCSRLTLQLAKTRRAENLAQLESDFEALLRKYYNRNLAEINLGEVLYEVLQVARTNKLKLPGNVGLYVK
ALANLEGAARTFDPKFNVLDEIKPLMSDLFRRQFVGEDPLPTLLRTALDVKNLSLRSPRQLEQLLDQVTSESLQWNLNLL
GLNGLRITVDNAANRLSFSILVGSLIMGAAMISAEKQTALYWLSNTLFAVASFLGLWLAVSILRSGNLR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=266, Percent_Identity=33.0827067669173, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI217035081, Length=222, Percent_Identity=32.8828828828829, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI41393593, Length=276, Percent_Identity=28.6231884057971, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI27363457, Length=276, Percent_Identity=24.2753623188406, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI217416386, Length=235, Percent_Identity=24.6808510638298, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI34147522, Length=286, Percent_Identity=21.6783216783217, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367309, Length=447, Percent_Identity=28.8590604026846, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17559152, Length=293, Percent_Identity=27.6450511945392, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17555620, Length=465, Percent_Identity=22.7956989247312, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=235, Percent_Identity=24.2553191489362, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323282, Length=246, Percent_Identity=30.4878048780488, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325148, Length=444, Percent_Identity=22.7477477477477, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=261, Percent_Identity=26.0536398467433, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24662575, Length=277, Percent_Identity=31.7689530685921, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI22024280, Length=322, Percent_Identity=26.3975155279503, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18859849, Length=269, Percent_Identity=25.2788104089219, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 61132; Mature: 61132

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGLTQTASRQRDIIEVVLRNGWDYMQQLLTGGKADQPALPTPAVLRNILVDLGPVYVK
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGQLLSTRPDILPAPYIDALSTLQSKVPPVAWPEIKAVIQQQIAQELRSQFKEIDPTPVA
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGSIAQVHRAILANGQQVAIKVQRPGIDVIVNQDIALINTLADLASRTDIGKDYDLKSLA
CCCHHHHHHHHHCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHH
AEFANALLDELDFTVEASHTEQLRQNLSTSRWFDPQQLVVPKINLALTTQKVLVMQWLDG
HHHHHHHHHHHCCEEECHHHHHHHHCCCHHCCCCCCHHCCCCCCEEEEHHHHHHHHCCCC
EPLLSANLPFSQQEPRIDSARRQVTTLLFRAFLQQIYVDGFFHADPHPGNLYYLNDGRAA
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
ILDCGMVGRLDPNTQQILTEMLLAIVDLDAQRCSRLTLQLAKTRRAENLAQLESDFEALL
EEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKYYNRNLAEINLGEVLYEVLQVARTNKLKLPGNVGLYVKALANLEGAARTFDPKFNVLD
HHHHCCCCCEECHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHCCCCCHHCCCCCCCHHH
EIKPLMSDLFRRQFVGEDPLPTLLRTALDVKNLSLRSPRQLEQLLDQVTSESLQWNLNLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEE
GLNGLRITVDNAANRLSFSILVGSLIMGAAMISAEKQTALYWLSNTLFAVASFLGLWLAV
EECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILRSGNLR
HHHHCCCCC
>Mature Secondary Structure
MFSGLTQTASRQRDIIEVVLRNGWDYMQQLLTGGKADQPALPTPAVLRNILVDLGPVYVK
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGQLLSTRPDILPAPYIDALSTLQSKVPPVAWPEIKAVIQQQIAQELRSQFKEIDPTPVA
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGSIAQVHRAILANGQQVAIKVQRPGIDVIVNQDIALINTLADLASRTDIGKDYDLKSLA
CCCHHHHHHHHHCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHH
AEFANALLDELDFTVEASHTEQLRQNLSTSRWFDPQQLVVPKINLALTTQKVLVMQWLDG
HHHHHHHHHHHCCEEECHHHHHHHHCCCHHCCCCCCHHCCCCCCEEEEHHHHHHHHCCCC
EPLLSANLPFSQQEPRIDSARRQVTTLLFRAFLQQIYVDGFFHADPHPGNLYYLNDGRAA
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
ILDCGMVGRLDPNTQQILTEMLLAIVDLDAQRCSRLTLQLAKTRRAENLAQLESDFEALL
EEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKYYNRNLAEINLGEVLYEVLQVARTNKLKLPGNVGLYVKALANLEGAARTFDPKFNVLD
HHHHCCCCCEECHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHCCCCCHHCCCCCCCHHH
EIKPLMSDLFRRQFVGEDPLPTLLRTALDVKNLSLRSPRQLEQLLDQVTSESLQWNLNLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEE
GLNGLRITVDNAANRLSFSILVGSLIMGAAMISAEKQTALYWLSNTLFAVASFLGLWLAV
EECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILRSGNLR
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]