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The map label for this gene is dfrA [H]

Identifier: 158334751

GI number: 158334751

Start: 1568029

End: 1569024

Strand: Reverse

Name: dfrA [H]

Synonym: AM1_1585

Alternate gene names: 158334751

Gene position: 1569024-1568029 (Counterclockwise)

Preceding gene: 158334753

Following gene: 158334750

Centisome position: 24.13

GC content: 50.6

Gene sequence:

>996_bases
ATGGCCAAATTAAATGTTTTTGTAACTGGTTCAACCGGATTTGTCGGAGCCAATCTAGTTCGTTTACTGTTGTCGGAAGG
TCATCAAGTCCGAGCCCTAGTCAGGCCCCAGAGCGATCTGACGAACCTCGCTGGGTTAGACGTGGAGCAAGTGACTGGAC
AGCTCACAGATGATGACTTGAGTCAAAAATTACAAGGGTGTCAGGTACTCTTTCATGTCGCGGCTCATTACAGCCTCTGG
CGGGCGGACCGCGAACAGCTTTGGCAGAGTAATGTAGAAGGCACACGCAATCTTTTGCAAGCAGCCCGAGACGCAGGGAT
TGAACGCACCGTTTACACCAGCTCAGTAGCAGCTATTGGCGTGAAAGCCGGGAATAGTGCTGATGAAACCTATCAGAGTC
CAGTGGAGAAACTGATTGGTGACTATAAAAAATCGAAATATTGGGCGGAGCAGGAAGCCCACAAAGCCGTCCAAATGGGC
CAGGATATTGTGATTGTCAATCCCAGCACTCCCATTGGCCCTTGGGATATTAAACCCACGCCCACAGGCGATATGATTTT
GCGATTTCTGCGGCGGCAGATGCCCTTTTATTTGAATACGGGGTTGAACCTTATCCATGTGCAAGACGTGGTTCTTGGCC
ATTTGCTAGCCCTAGAAAAGGGAAAAACAGGAGAGCGCTATATTCTGGGCAATCAGAATATGACCCTAAAAGAAATGCTG
GATGTGCTGGCTGAATTAACGGGGTTGTCCGCTCCCAAAGGCGAGATTCCTGCATGGATTCCCCTGACCACGGCCTGGAT
CGATGAAGTGGTTTTGGCGGCGATGGGCAAAACTCCCTCTGTGCCCTTAGCCGGGGTACAAATGGCCAAGCAAATGATGT
TTTACAACCCTGCCAAAGCGATTCAAGAATTGGGACTGCCCCAAACCCCAGTCCGTCAGGCGCTGCAAGAGGCCGTCGAT
TGGTTTGTCAGCCATGACTACGTTCCCCAGACTTAA

Upstream 100 bases:

>100_bases
AATCTGCAGAAATATTGTTTTCTTTGCCGATGCCTGTAAGGTAAAACATTAACCTTGTTTACCCCTACTAGACCACCCAA
AGTGGCAAAGAGCCTGAGTT

Downstream 100 bases:

>100_bases
TACAGACTGCAATTTTTTGAGTCTGAATCCTGCAAAATGCATAGGGCAGCGTTAAATTAACGATAGAGTAATGTGTTCCT
CCTGAGACTCGCAAACTCTA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAKLNVFVTGSTGFVGANLVRLLLSEGHQVRALVRPQSDLTNLAGLDVEQVTGQLTDDDLSQKLQGCQVLFHVAAHYSLW
RADREQLWQSNVEGTRNLLQAARDAGIERTVYTSSVAAIGVKAGNSADETYQSPVEKLIGDYKKSKYWAEQEAHKAVQMG
QDIVIVNPSTPIGPWDIKPTPTGDMILRFLRRQMPFYLNTGLNLIHVQDVVLGHLLALEKGKTGERYILGNQNMTLKEML
DVLAELTGLSAPKGEIPAWIPLTTAWIDEVVLAAMGKTPSVPLAGVQMAKQMMFYNPAKAIQELGLPQTPVRQALQEAVD
WFVSHDYVPQT

Sequences:

>Translated_331_residues
MAKLNVFVTGSTGFVGANLVRLLLSEGHQVRALVRPQSDLTNLAGLDVEQVTGQLTDDDLSQKLQGCQVLFHVAAHYSLW
RADREQLWQSNVEGTRNLLQAARDAGIERTVYTSSVAAIGVKAGNSADETYQSPVEKLIGDYKKSKYWAEQEAHKAVQMG
QDIVIVNPSTPIGPWDIKPTPTGDMILRFLRRQMPFYLNTGLNLIHVQDVVLGHLLALEKGKTGERYILGNQNMTLKEML
DVLAELTGLSAPKGEIPAWIPLTTAWIDEVVLAAMGKTPSVPLAGVQMAKQMMFYNPAKAIQELGLPQTPVRQALQEAVD
WFVSHDYVPQT
>Mature_330_residues
AKLNVFVTGSTGFVGANLVRLLLSEGHQVRALVRPQSDLTNLAGLDVEQVTGQLTDDDLSQKLQGCQVLFHVAAHYSLWR
ADREQLWQSNVEGTRNLLQAARDAGIERTVYTSSVAAIGVKAGNSADETYQSPVEKLIGDYKKSKYWAEQEAHKAVQMGQ
DIVIVNPSTPIGPWDIKPTPTGDMILRFLRRQMPFYLNTGLNLIHVQDVVLGHLLALEKGKTGERYILGNQNMTLKEMLD
VLAELTGLSAPKGEIPAWIPLTTAWIDEVVLAAMGKTPSVPLAGVQMAKQMMFYNPAKAIQELGLPQTPVRQALQEAVDW
FVSHDYVPQT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=331, Percent_Identity=29.3051359516616, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 36483; Mature: 36352

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLNVFVTGSTGFVGANLVRLLLSEGHQVRALVRPQSDLTNLAGLDVEQVTGQLTDDDL
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHCCCCHHHH
SQKLQGCQVLFHVAAHYSLWRADREQLWQSNVEGTRNLLQAARDAGIERTVYTSSVAAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHEEE
VKAGNSADETYQSPVEKLIGDYKKSKYWAEQEAHKAVQMGQDIVIVNPSTPIGPWDIKPT
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
PTGDMILRFLRRQMPFYLNTGLNLIHVQDVVLGHLLALEKGKTGERYILGNQNMTLKEML
CCHHHHHHHHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
DVLAELTGLSAPKGEIPAWIPLTTAWIDEVVLAAMGKTPSVPLAGVQMAKQMMFYNPAKA
HHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
IQELGLPQTPVRQALQEAVDWFVSHDYVPQT
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKLNVFVTGSTGFVGANLVRLLLSEGHQVRALVRPQSDLTNLAGLDVEQVTGQLTDDDL
CEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHCCCCHHHH
SQKLQGCQVLFHVAAHYSLWRADREQLWQSNVEGTRNLLQAARDAGIERTVYTSSVAAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHEEE
VKAGNSADETYQSPVEKLIGDYKKSKYWAEQEAHKAVQMGQDIVIVNPSTPIGPWDIKPT
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
PTGDMILRFLRRQMPFYLNTGLNLIHVQDVVLGHLLALEKGKTGERYILGNQNMTLKEML
CCHHHHHHHHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
DVLAELTGLSAPKGEIPAWIPLTTAWIDEVVLAAMGKTPSVPLAGVQMAKQMMFYNPAKA
HHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
IQELGLPQTPVRQALQEAVDWFVSHDYVPQT
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]