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The map label for this gene is gcvT [H]

Identifier: 158334606

GI number: 158334606

Start: 1427214

End: 1428278

Strand: Reverse

Name: gcvT [H]

Synonym: AM1_1436

Alternate gene names: 158334606

Gene position: 1428278-1427214 (Counterclockwise)

Preceding gene: 158334608

Following gene: 158334605

Centisome position: 21.96

GC content: 49.39

Gene sequence:

>1065_bases
ATGTCAGAGACCTTACAGGACTGTCAACGCCAAAATGGAGCAGTATGGGCTGAGGATCAGGGTTCTATCCTCAGCTTTGG
CAATGATAAATTCGCCTTAAAGGCGGTTCAAAATGGAGCAGCCCTCTGGGATCGTACCCATTGGGGGCGTCTGCAGTTCA
CCGATCAGGATCGACTGTCTTTTCTTCATAACCAGACCACCAATACTTTCAAAACTCTGAAGCCAGGTGAAGGTTGTGAA
AGCGTGTTTGTAACATCCACGGCTCGCACTATTGATCTGGTGAGTGCATACGTGACGGAAGAGGCCGTTTTGCTACTGGT
CTCTCCAACTCGACGAGCACAATTGATGAGCTGGTGCGATCGCTATATCTTCTTTGGAGACAAGGTCAAGATTGAGGATA
TTACGACCCAAACGATTACCTTTAGTCTATTGGGGCCTGAAAGTTCACGACTTCTGCACAAACTGGGAATTTCAGACCTA
CCGGAATCTCCTCATCATCACATTACAACTCAAATTAAAGGCCATACTGTTCGTGTTGCGTCAGGCAGTGGGCTGACAAC
ACCAGGCTATACCTTGTTTGCCGATGCTGAAGTGGGGGCTGATCTATGGCAAGCCTTAACGGAACAGGATGCCTGTCCCT
TGGGGGAGAAGGTTTGGGAACAGTTAAGAGTGTCGGAAGGGCGACCGAAGCCTGATGCTGAATTAACAGAGGACTTTAAC
CCTTTAGAAGCCGGACTCTGGCAGACTATTTCTTTTGATAAAGGGTGCTATATCGGCCAAGAAACGATTGCTCGTCTTAA
CACTTATCAAGGCGTCAAACAGCGACTCTGGGGGATTCAGCTCGGTGAATCTGTCTCTGTTGATACGCCCATCACGCTTG
AAGACAAAAAGGTGGGGGTATTGACGAGTTTGGTTGAGACTGCTGAGGGGCCTGTGGGGTTAGGCTATGTCAAAACAAAA
GCGGGGGATGCAGGCGCTCAAGTTTCGGTAGGAACCGTAACCGGAACGTTAGTGGAAGTTCCGTTTCTCACCTATCCCCA
GTGGACCCCTGACCCGACTCCTTAG

Upstream 100 bases:

>100_bases
GTTCTTGAATAAACTGTTAACAACCCAAGGGATTTAGCCCTCCTCATTCACGGAAATAATAAAATCAACCTTGCCCCAGA
AATAACGGATAAACGCCGCA

Downstream 100 bases:

>100_bases
AGCGGTTAGAAAGACCATTCTTCTCTAGTCTGTTTGTGTCCTGGATCAGGTACATTCAAAAGGAACGCTATGCATGTGGG
AATTGTGACACAAACCTATC

Product: glycine cleavage T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSETLQDCQRQNGAVWAEDQGSILSFGNDKFALKAVQNGAALWDRTHWGRLQFTDQDRLSFLHNQTTNTFKTLKPGEGCE
SVFVTSTARTIDLVSAYVTEEAVLLLVSPTRRAQLMSWCDRYIFFGDKVKIEDITTQTITFSLLGPESSRLLHKLGISDL
PESPHHHITTQIKGHTVRVASGSGLTTPGYTLFADAEVGADLWQALTEQDACPLGEKVWEQLRVSEGRPKPDAELTEDFN
PLEAGLWQTISFDKGCYIGQETIARLNTYQGVKQRLWGIQLGESVSVDTPITLEDKKVGVLTSLVETAEGPVGLGYVKTK
AGDAGAQVSVGTVTGTLVEVPFLTYPQWTPDPTP

Sequences:

>Translated_354_residues
MSETLQDCQRQNGAVWAEDQGSILSFGNDKFALKAVQNGAALWDRTHWGRLQFTDQDRLSFLHNQTTNTFKTLKPGEGCE
SVFVTSTARTIDLVSAYVTEEAVLLLVSPTRRAQLMSWCDRYIFFGDKVKIEDITTQTITFSLLGPESSRLLHKLGISDL
PESPHHHITTQIKGHTVRVASGSGLTTPGYTLFADAEVGADLWQALTEQDACPLGEKVWEQLRVSEGRPKPDAELTEDFN
PLEAGLWQTISFDKGCYIGQETIARLNTYQGVKQRLWGIQLGESVSVDTPITLEDKKVGVLTSLVETAEGPVGLGYVKTK
AGDAGAQVSVGTVTGTLVEVPFLTYPQWTPDPTP
>Mature_353_residues
SETLQDCQRQNGAVWAEDQGSILSFGNDKFALKAVQNGAALWDRTHWGRLQFTDQDRLSFLHNQTTNTFKTLKPGEGCES
VFVTSTARTIDLVSAYVTEEAVLLLVSPTRRAQLMSWCDRYIFFGDKVKIEDITTQTITFSLLGPESSRLLHKLGISDLP
ESPHHHITTQIKGHTVRVASGSGLTTPGYTLFADAEVGADLWQALTEQDACPLGEKVWEQLRVSEGRPKPDAELTEDFNP
LEAGLWQTISFDKGCYIGQETIARLNTYQGVKQRLWGIQLGESVSVDTPITLEDKKVGVLTSLVETAEGPVGLGYVKTKA
GDAGAQVSVGTVTGTLVEVPFLTYPQWTPDPTP

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:
GO:0004047: Glycine cleavage T protein, putative
GO:0005737: Glycine cleavage T protein, putative
GO:0006546: Glycine cleavage T protein, putative

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

None

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 38861; Mature: 38730

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLQDCQRQNGAVWAEDQGSILSFGNDKFALKAVQNGAALWDRTHWGRLQFTDQDRLS
CCHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEHHCCCHHHCCCCCCEEEECCHHHHH
FLHNQTTNTFKTLKPGEGCESVFVTSTARTIDLVSAYVTEEAVLLLVSPTRRAQLMSWCD
HHHCCCCCCEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
RYIFFGDKVKIEDITTQTITFSLLGPESSRLLHKLGISDLPESPHHHITTQIKGHTVRVA
HHEEECCEEEEEEEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEE
SGSGLTTPGYTLFADAEVGADLWQALTEQDACPLGEKVWEQLRVSEGRPKPDAELTEDFN
CCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCC
PLEAGLWQTISFDKGCYIGQETIARLNTYQGVKQRLWGIQLGESVSVDTPITLEDKKVGV
HHHHHHHHEECCCCCCEECHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCEEECCCCHHH
LTSLVETAEGPVGLGYVKTKAGDAGAQVSVGTVTGTLVEVPFLTYPQWTPDPTP
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEECCEEECCCCCCCCCC
>Mature Secondary Structure 
SETLQDCQRQNGAVWAEDQGSILSFGNDKFALKAVQNGAALWDRTHWGRLQFTDQDRLS
CHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEHHCCCHHHCCCCCCEEEECCHHHHH
FLHNQTTNTFKTLKPGEGCESVFVTSTARTIDLVSAYVTEEAVLLLVSPTRRAQLMSWCD
HHHCCCCCCEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
RYIFFGDKVKIEDITTQTITFSLLGPESSRLLHKLGISDLPESPHHHITTQIKGHTVRVA
HHEEECCEEEEEEEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEE
SGSGLTTPGYTLFADAEVGADLWQALTEQDACPLGEKVWEQLRVSEGRPKPDAELTEDFN
CCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCC
PLEAGLWQTISFDKGCYIGQETIARLNTYQGVKQRLWGIQLGESVSVDTPITLEDKKVGV
HHHHHHHHEECCCCCCEECHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCEEECCCCHHH
LTSLVETAEGPVGLGYVKTKAGDAGAQVSVGTVTGTLVEVPFLTYPQWTPDPTP
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]