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The map label for this gene is pabA [H]

Identifier: 158334600

GI number: 158334600

Start: 1423838

End: 1424437

Strand: Reverse

Name: pabA [H]

Synonym: AM1_1430

Alternate gene names: 158334600

Gene position: 1424437-1423838 (Counterclockwise)

Preceding gene: 158334601

Following gene: 158334599

Centisome position: 21.9

GC content: 47.5

Gene sequence:

>600_bases
TTGCTACTGGTTGTTGATAATTACGACAGCTTTACTTACAACCTGGTTCAGTATTTGGGAGAACTCGCCACTGAATTTGA
AGTGGCCCAAGATATTCAGGTTTTTCGCAATGATCAGATTACCCTAGCCGAAGTTGAGAAGCTCCAACCCGATGCAATCG
TTATATCTCCAGGGCCGGGACGGCCTCAAGATGCTGGAATTTCTCTAGAGCTGATTGAGCAATTGGGTGCAACCGTACCG
ATCTTGGGAGTCTGTTTAGGCCATCAGAGTATTGGCCAAGTGTTTGGTGGCGATATTGTGTCTGCCCCAGTGCTTATGCA
TGGTAAAACATCCCCTATCCGTCATAAATCCACGGGGGTTTTTTCCGGGTTAGATAATCCTTTTACCGCAACTCGGTATC
ATAGTCTGGTGATAGAGAAGGAAACCTGTCCAGAGGTCCTAGAGATTACGGCTTGGACTGAGGACGGCACGATTATGGGG
GTGCGTCATCGGAACTATCCTCACATTGAAGGCGTCCAGTTTCACCCAGAGAGTATTTTGACGACATCTGGGAAACAACT
GCTCAAGAATTTTCTGAGCCACCTTCCTACCGATGGCTAA

Upstream 100 bases:

>100_bases
TTTGATGACAGCGCTGTTTGCAGTCAGGTTTATAGCTGCAAAGTAGGATAAACACGCTAAGTTGGAGAGATAACTTTCTC
TTGGGACAGGAGCGCAAGCC

Downstream 100 bases:

>100_bases
TACTGATCGGGTTTCACAGGACACACATTCAGGGATACATCACAGAGAACTATGAACCGTCGCCGCTTCATGCACTATGT
GCAAGCAGGATTGATCACCA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLLVVDNYDSFTYNLVQYLGELATEFEVAQDIQVFRNDQITLAEVEKLQPDAIVISPGPGRPQDAGISLELIEQLGATVP
ILGVCLGHQSIGQVFGGDIVSAPVLMHGKTSPIRHKSTGVFSGLDNPFTATRYHSLVIEKETCPEVLEITAWTEDGTIMG
VRHRNYPHIEGVQFHPESILTTSGKQLLKNFLSHLPTDG

Sequences:

>Translated_199_residues
MLLVVDNYDSFTYNLVQYLGELATEFEVAQDIQVFRNDQITLAEVEKLQPDAIVISPGPGRPQDAGISLELIEQLGATVP
ILGVCLGHQSIGQVFGGDIVSAPVLMHGKTSPIRHKSTGVFSGLDNPFTATRYHSLVIEKETCPEVLEITAWTEDGTIMG
VRHRNYPHIEGVQFHPESILTTSGKQLLKNFLSHLPTDG
>Mature_199_residues
MLLVVDNYDSFTYNLVQYLGELATEFEVAQDIQVFRNDQITLAEVEKLQPDAIVISPGPGRPQDAGISLELIEQLGATVP
ILGVCLGHQSIGQVFGGDIVSAPVLMHGKTSPIRHKSTGVFSGLDNPFTATRYHSLVIEKETCPEVLEITAWTEDGTIMG
VRHRNYPHIEGVQFHPESILTTSGKQLLKNFLSHLPTDG

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:
GO:0003824: Anthranilate synthase component II
GO:0004049: Anthranilate synthase component II
GO:0006541: Anthranilate synthase component II
GO:0008152: Anthranilate synthase component II
GO:0009058: Anthranilate synthase component II

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=56.7708333333333, Blast_Score=230, Evalue=4e-62,
Organism=Escherichia coli, GI1787517, Length=195, Percent_Identity=40, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786215, Length=142, Percent_Identity=28.169014084507, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=193, Percent_Identity=45.0777202072539, Blast_Score=186, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=32.7014218009479, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281365319, Length=117, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21806; Mature: 21806

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVVDNYDSFTYNLVQYLGELATEFEVAQDIQVFRNDQITLAEVEKLQPDAIVISPGPG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEECCCCC
RPQDAGISLELIEQLGATVPILGVCLGHQSIGQVFGGDIVSAPVLMHGKTSPIRHKSTGV
CCCCCCCHHHHHHHCCCCCCHHHHHHCCHHHHHHHCCCHHHCCEEECCCCCCCCCCCCCC
FSGLDNPFTATRYHSLVIEKETCPEVLEITAWTEDGTIMGVRHRNYPHIEGVQFHPESIL
CCCCCCCCCHHHHEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCEEECCHHHH
TTSGKQLLKNFLSHLPTDG
HCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLVVDNYDSFTYNLVQYLGELATEFEVAQDIQVFRNDQITLAEVEKLQPDAIVISPGPG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEECCCCC
RPQDAGISLELIEQLGATVPILGVCLGHQSIGQVFGGDIVSAPVLMHGKTSPIRHKSTGV
CCCCCCCHHHHHHHCCCCCCHHHHHHCCHHHHHHHCCCHHHCCEEECCCCCCCCCCCCCC
FSGLDNPFTATRYHSLVIEKETCPEVLEITAWTEDGTIMGVRHRNYPHIEGVQFHPESIL
CCCCCCCCCHHHHEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCEEECCHHHH
TTSGKQLLKNFLSHLPTDG
HCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]