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The map label for this gene is manC [H]

Identifier: 158334588

GI number: 158334588

Start: 1398875

End: 1399267

Strand: Reverse

Name: manC [H]

Synonym: AM1_1415

Alternate gene names: 158334588

Gene position: 1399267-1398875 (Counterclockwise)

Preceding gene: 158334589

Following gene: 158334587

Centisome position: 21.51

GC content: 49.11

Gene sequence:

>393_bases
ATGTCTAATTTTCCAATGAGTGCCCATCCCACTCCTATTAGAAAGAACGCCCATCTAGAACAGCAACCTTGGGGCACACT
GACCATTCTGGATACAGGTCCTAGTTATCAAATTAAGCGATTGGAAGTTAATCCAGGGCAAAGCTTGGGGCGACAGCTCC
ATCAGCACCTCAATATTCATTGGATTGTGGTGGCAGGGCTCGCTAAGGTCACGGATAACACGAAAAAAATGCTGTTAGGA
GCCGATCAGTCTTGGTATGTGCCTCGCCAGACCTGCCATTGCTTAGAAAATCCTGGGCGCTTCCCTCTGACATTGATGGC
AGTAGAGCATTGTGTGTTCTTAGGGGAAGGGGACAGCCTCCAGGGCAGTGTAGGCTATCTCTGTTCTGCTTAG

Upstream 100 bases:

>100_bases
CGTTTTCAGGGCTGCCTAGGATTCAGTGAGTCCGGGAGTAACTCAAGATGAATCTGGCCCAATTTATACCTTTACCTTCA
ATGATTAAGAGCAACGAAGA

Downstream 100 bases:

>100_bases
GGCACATTCTGAATTTGGTGTAACTCAAAGAAAATAAGGATTTTGGGAGGTTTCAGTATCCAGGTATCAAAACATACAGT
TTAGAGATATCAAGTTACCA

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSNFPMSAHPTPIRKNAHLEQQPWGTLTILDTGPSYQIKRLEVNPGQSLGRQLHQHLNIHWIVVAGLAKVTDNTKKMLLG
ADQSWYVPRQTCHCLENPGRFPLTLMAVEHCVFLGEGDSLQGSVGYLCSA

Sequences:

>Translated_130_residues
MSNFPMSAHPTPIRKNAHLEQQPWGTLTILDTGPSYQIKRLEVNPGQSLGRQLHQHLNIHWIVVAGLAKVTDNTKKMLLG
ADQSWYVPRQTCHCLENPGRFPLTLMAVEHCVFLGEGDSLQGSVGYLCSA
>Mature_129_residues
SNFPMSAHPTPIRKNAHLEQQPWGTLTILDTGPSYQIKRLEVNPGQSLGRQLHQHLNIHWIVVAGLAKVTDNTKKMLLGA
DQSWYVPRQTCHCLENPGRFPLTLMAVEHCVFLGEGDSLQGSVGYLCSA

Specific function: Involved in the biosynthesis of the capsular polysaccharide colanic acid [H]

COG id: COG0662

COG function: function code G; Mannose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=100, Percent_Identity=46, Blast_Score=103, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 14445; Mature: 14314

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFPMSAHPTPIRKNAHLEQQPWGTLTILDTGPSYQIKRLEVNPGQSLGRQLHQHLNIH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCEE
WIVVAGLAKVTDNTKKMLLGADQSWYVPRQTCHCLENPGRFPLTLMAVEHCVFLGEGDSL
EEEEECHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHEEEHHEEEECCCCCC
QGSVGYLCSA
CCCCCEEECC
>Mature Secondary Structure 
SNFPMSAHPTPIRKNAHLEQQPWGTLTILDTGPSYQIKRLEVNPGQSLGRQLHQHLNIH
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCEE
WIVVAGLAKVTDNTKKMLLGADQSWYVPRQTCHCLENPGRFPLTLMAVEHCVFLGEGDSL
EEEEECHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHEEEHHEEEECCCCCC
QGSVGYLCSA
CCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1712067; 11677609 [H]