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The map label for this gene is 158334579

Identifier: 158334579

GI number: 158334579

Start: 1388723

End: 1391074

Strand: Reverse

Name: 158334579

Synonym: AM1_1406

Alternate gene names: NA

Gene position: 1391074-1388723 (Counterclockwise)

Preceding gene: 158334580

Following gene: 158334578

Centisome position: 21.39

GC content: 50.55

Gene sequence:

>2352_bases
TTGCCCAACAACTCACCTCCTGCTGGCAGTAACCCAGTAGATGAAGGGGGTGCTTTGGCTAAAATGTATGGCGAGAATCT
CCATAATCCCGATGCTCTAATTAATCGAGCCAATAAGCGGGCCACGAACGGGGATCTAGATGGGGCCTTGGGAGACTTTG
ACGAAGCGATAGCCCTCAACCCAGCTAAGGCCACGGCCTATTTTAATCGAGGTTTTCTGTTCAATTCCCTGGGGAAGTTT
GAAGCTGCTATTCACGACTTTTCTGAGGCGATCGAGCTACTCCCAGATTATGATGAAGCCTATTTTCAACGGGGTAATAG
TTATCGTCAACGCGGTGAGTTTCAGCGAGCGATTCAAGATTATAGTCAAGCGATTCGCATTAATCCCTATTGCATCAAAG
CCTACTATAAACGAGCTGATAGTCGGGCTGAGTTAGGGGATCATCCTGGTGCTTTGACGGATTTCAGTCAGGTTATTCTG
CGGTTACCCAAGGATGCGAATGCCTATTGTCAGCGGGGAATATTTCTCAGTCAGAGTGGTGAGTTGGAGAAGGCGATTGA
AGACTTTACATCGGCCATTGAACATAACCCTCGATTAGCAGATGCATACTTTCATCGGGGCTATTGCCTCGCCCAAATGG
GAGAAGCTGAGAAGGCCTCTAAGGATTTTAGTGAAGCCTTGCTGCATGATCCGAACCATCAGGCTGCTTATACACGGGCT
TATGCATTGGGGATGTTAAAAGAGACTCCAGTTGATGTCTCTTCTCCCAGCTCAACGGCAACGGATTACCCCCTGTCCCT
ACTGGAAGAAAGCGTTCCTGTTTCCGTGGAGCCGGTGGAAGATTCTGACGGTGAGCAAGAGCCTCATCCCGCAACAGTGC
CCCTAGAACCCACGTCCATGGAAGGGTTCTTCGAGCGGGCGAATAATCGTATCCAGCGCGGTGACTTGGATGGAGCAATT
TCAGATTACTCCAAGATCATTGATACTGATCCAGAAAATAGTCAAGCCTATTATCAACGAGGACAAAGCCTTGGGGCCTT
GGGTGAATCCCAAGCAGCCATGGAAGATCTGAATCAGGCGATTCATTGGGCCCGGGTGCATTCTTTGGGGCTGATGCGGG
ATTTTAGTGGCGAATTGTCGACGACTCTAGAGACGTTGAAGCAGGATCTGAAGGAGCTGTCTTATCAGAGTCCGTTTGCC
AAAACTCACCCATTACCAGGGACTGCTGCTGACCAGATGCAACAAGCAGATCCATCTGCTGATGATGTGATTGATGTTTC
TAGCGATCAACCAGACGCTAGCGGGGAATTAAAAACAGTTGAGAATTCTAATTCATCTATTACACAACCGACTTCGGCAA
AAGAGTCTGCGGTTACGGATGTTTCCATAGATACACAGTCTTCTGAACCAGAGTCATCATCCATCTTTACGCAGAAAGAA
CCGCCAGCTCAGGTAAATCCCCAACCCTCTTCTCCTCAGCCTCAGTCACCACCTCCAGACGCTGAGATAGCGGCCCCGAC
CCTAGAACGGGCGATTGCCCAGCATACTCGTGCCATTGAACAGAACCCATTGGATGCAGATGCCTTTTTTAATCGAGGTC
AGAGTCGAGCCTTAGGTGGAGATTTGCAAGGTGCCATTGAAGATTATTCTCGTACGATTCGCCTCGATCCGCATAACCGA
GAAGCTTATGTTAAACGAGCGCGTTGCCTGTCTGCCCTAGGGGATGAGACGGCGGCCCAGGCCGACTTAAACCATGTGAT
TCGCCAATCCCCTAAGCGCCCTCAGCCGCAACCCTTGAAAACGGCATCAGCCCCCCCCTCCACTGAGTTTTCTCAACCCC
AAGGGGCGCCGTCTCCTGCTGCCTCAACGCCGCCGTCTCCACCTCAGGTGGATGATGCTACCCATTCGATGGCGTCCCTG
TTTCAACAAGAAAATGAAATCCTGCAGTCTACACAAACTTCACAGAAGTCCTGTACCCATGAGGGGAATAGCCCAGGCAA
TCAGTTCTGTATTCATTGTGGTGCATCTCTGAGTCCCCTGTCTCGCTATAGCAGCGACTTCTCAGCACCGCCGCCAGACT
CCCCGCCAGGAGAGAAGGTGAAGCCTGTTGCTAGTAATCGGAAACAACGATTACAAGAAGCCGAACAATATTATGACCAA
GGCGTTGCTTTATTTAGAGATGGCGACCGCCAGGGCAGCTTACAGTCTTTATCAGCAGGGCTCAAGATCTTTCTGGAGCA
GCGAGAGATGCAGCGGTATCAACAGACCCTCAACTTTATGCAAGATGTGGCGCATGCCCTCAACGATACCGGAGAAGATG
AGGCCGACCCCGATGATAGTCTCCTCCTGTAG

Upstream 100 bases:

>100_bases
TATTGATATTGAACACGAGAATTCTTTTTCTTCACTGATCTTTCTTGACAGCAACCTAGGCCCTCAAGTGACTGATTTTT
TAAGGAGAATCCGCAAGATA

Downstream 100 bases:

>100_bases
ACCATCTAGGCTAAAATCCAGAAGCTGATCTGTTTTCGGCGTTGTGTCATCTATGCTGCAATCATGGTTACCTTGATTTT
GTACAGTAAACCCGGATGTC

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MPNNSPPAGSNPVDEGGALAKMYGENLHNPDALINRANKRATNGDLDGALGDFDEAIALNPAKATAYFNRGFLFNSLGKF
EAAIHDFSEAIELLPDYDEAYFQRGNSYRQRGEFQRAIQDYSQAIRINPYCIKAYYKRADSRAELGDHPGALTDFSQVIL
RLPKDANAYCQRGIFLSQSGELEKAIEDFTSAIEHNPRLADAYFHRGYCLAQMGEAEKASKDFSEALLHDPNHQAAYTRA
YALGMLKETPVDVSSPSSTATDYPLSLLEESVPVSVEPVEDSDGEQEPHPATVPLEPTSMEGFFERANNRIQRGDLDGAI
SDYSKIIDTDPENSQAYYQRGQSLGALGESQAAMEDLNQAIHWARVHSLGLMRDFSGELSTTLETLKQDLKELSYQSPFA
KTHPLPGTAADQMQQADPSADDVIDVSSDQPDASGELKTVENSNSSITQPTSAKESAVTDVSIDTQSSEPESSSIFTQKE
PPAQVNPQPSSPQPQSPPPDAEIAAPTLERAIAQHTRAIEQNPLDADAFFNRGQSRALGGDLQGAIEDYSRTIRLDPHNR
EAYVKRARCLSALGDETAAQADLNHVIRQSPKRPQPQPLKTASAPPSTEFSQPQGAPSPAASTPPSPPQVDDATHSMASL
FQQENEILQSTQTSQKSCTHEGNSPGNQFCIHCGASLSPLSRYSSDFSAPPPDSPPGEKVKPVASNRKQRLQEAEQYYDQ
GVALFRDGDRQGSLQSLSAGLKIFLEQREMQRYQQTLNFMQDVAHALNDTGEDEADPDDSLLL

Sequences:

>Translated_783_residues
MPNNSPPAGSNPVDEGGALAKMYGENLHNPDALINRANKRATNGDLDGALGDFDEAIALNPAKATAYFNRGFLFNSLGKF
EAAIHDFSEAIELLPDYDEAYFQRGNSYRQRGEFQRAIQDYSQAIRINPYCIKAYYKRADSRAELGDHPGALTDFSQVIL
RLPKDANAYCQRGIFLSQSGELEKAIEDFTSAIEHNPRLADAYFHRGYCLAQMGEAEKASKDFSEALLHDPNHQAAYTRA
YALGMLKETPVDVSSPSSTATDYPLSLLEESVPVSVEPVEDSDGEQEPHPATVPLEPTSMEGFFERANNRIQRGDLDGAI
SDYSKIIDTDPENSQAYYQRGQSLGALGESQAAMEDLNQAIHWARVHSLGLMRDFSGELSTTLETLKQDLKELSYQSPFA
KTHPLPGTAADQMQQADPSADDVIDVSSDQPDASGELKTVENSNSSITQPTSAKESAVTDVSIDTQSSEPESSSIFTQKE
PPAQVNPQPSSPQPQSPPPDAEIAAPTLERAIAQHTRAIEQNPLDADAFFNRGQSRALGGDLQGAIEDYSRTIRLDPHNR
EAYVKRARCLSALGDETAAQADLNHVIRQSPKRPQPQPLKTASAPPSTEFSQPQGAPSPAASTPPSPPQVDDATHSMASL
FQQENEILQSTQTSQKSCTHEGNSPGNQFCIHCGASLSPLSRYSSDFSAPPPDSPPGEKVKPVASNRKQRLQEAEQYYDQ
GVALFRDGDRQGSLQSLSAGLKIFLEQREMQRYQQTLNFMQDVAHALNDTGEDEADPDDSLLL
>Mature_782_residues
PNNSPPAGSNPVDEGGALAKMYGENLHNPDALINRANKRATNGDLDGALGDFDEAIALNPAKATAYFNRGFLFNSLGKFE
AAIHDFSEAIELLPDYDEAYFQRGNSYRQRGEFQRAIQDYSQAIRINPYCIKAYYKRADSRAELGDHPGALTDFSQVILR
LPKDANAYCQRGIFLSQSGELEKAIEDFTSAIEHNPRLADAYFHRGYCLAQMGEAEKASKDFSEALLHDPNHQAAYTRAY
ALGMLKETPVDVSSPSSTATDYPLSLLEESVPVSVEPVEDSDGEQEPHPATVPLEPTSMEGFFERANNRIQRGDLDGAIS
DYSKIIDTDPENSQAYYQRGQSLGALGESQAAMEDLNQAIHWARVHSLGLMRDFSGELSTTLETLKQDLKELSYQSPFAK
THPLPGTAADQMQQADPSADDVIDVSSDQPDASGELKTVENSNSSITQPTSAKESAVTDVSIDTQSSEPESSSIFTQKEP
PAQVNPQPSSPQPQSPPPDAEIAAPTLERAIAQHTRAIEQNPLDADAFFNRGQSRALGGDLQGAIEDYSRTIRLDPHNRE
AYVKRARCLSALGDETAAQADLNHVIRQSPKRPQPQPLKTASAPPSTEFSQPQGAPSPAASTPPSPPQVDDATHSMASLF
QQENEILQSTQTSQKSCTHEGNSPGNQFCIHCGASLSPLSRYSSDFSAPPPDSPPGEKVKPVASNRKQRLQEAEQYYDQG
VALFRDGDRQGSLQSLSAGLKIFLEQREMQRYQQTLNFMQDVAHALNDTGEDEADPDDSLLL

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310110582, Length=343, Percent_Identity=25.9475218658892, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI310131789, Length=343, Percent_Identity=25.9475218658892, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI310123097, Length=343, Percent_Identity=25.9475218658892, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI32307148, Length=316, Percent_Identity=24.3670886075949, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI32307150, Length=316, Percent_Identity=24.3670886075949, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI170784867, Length=280, Percent_Identity=24.2857142857143, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI296531396, Length=266, Percent_Identity=24.4360902255639, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI21450645, Length=213, Percent_Identity=24.8826291079812, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI5453980, Length=313, Percent_Identity=23.961661341853, Blast_Score=67, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=366, Percent_Identity=23.224043715847, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=182, Percent_Identity=28.021978021978, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563052, Length=225, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319589, Length=347, Percent_Identity=23.9193083573487, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647755, Length=181, Percent_Identity=28.7292817679558, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585827, Length=181, Percent_Identity=28.7292817679558, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585829, Length=181, Percent_Identity=28.7292817679558, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 85466; Mature: 85335

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNSPPAGSNPVDEGGALAKMYGENLHNPDALINRANKRATNGDLDGALGDFDEAIALN
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCC
PAKATAYFNRGFLFNSLGKFEAAIHDFSEAIELLPDYDEAYFQRGNSYRQRGEFQRAIQD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
YSQAIRINPYCIKAYYKRADSRAELGDHPGALTDFSQVILRLPKDANAYCQRGIFLSQSG
HHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCCEEECCCC
ELEKAIEDFTSAIEHNPRLADAYFHRGYCLAQMGEAEKASKDFSEALLHDPNHQAAYTRA
CHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHH
YALGMLKETPVDVSSPSSTATDYPLSLLEESVPVSVEPVEDSDGEQEPHPATVPLEPTSM
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
EGFFERANNRIQRGDLDGAISDYSKIIDTDPENSQAYYQRGQSLGALGESQAAMEDLNQA
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCHHHHHHHHHHHH
IHWARVHSLGLMRDFSGELSTTLETLKQDLKELSYQSPFAKTHPLPGTAADQMQQADPSA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCC
DDVIDVSSDQPDASGELKTVENSNSSITQPTSAKESAVTDVSIDTQSSEPESSSIFTQKE
CCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCC
PPAQVNPQPSSPQPQSPPPDAEIAAPTLERAIAQHTRAIEQNPLDADAFFNRGQSRALGG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC
DLQGAIEDYSRTIRLDPHNREAYVKRARCLSALGDETAAQADLNHVIRQSPKRPQPQPLK
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
TASAPPSTEFSQPQGAPSPAASTPPSPPQVDDATHSMASLFQQENEILQSTQTSQKSCTH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGNSPGNQFCIHCGASLSPLSRYSSDFSAPPPDSPPGEKVKPVASNRKQRLQEAEQYYDQ
CCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVALFRDGDRQGSLQSLSAGLKIFLEQREMQRYQQTLNFMQDVAHALNDTGEDEADPDDS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LLL
CCC
>Mature Secondary Structure 
PNNSPPAGSNPVDEGGALAKMYGENLHNPDALINRANKRATNGDLDGALGDFDEAIALN
CCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCC
PAKATAYFNRGFLFNSLGKFEAAIHDFSEAIELLPDYDEAYFQRGNSYRQRGEFQRAIQD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
YSQAIRINPYCIKAYYKRADSRAELGDHPGALTDFSQVILRLPKDANAYCQRGIFLSQSG
HHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCCEEECCCC
ELEKAIEDFTSAIEHNPRLADAYFHRGYCLAQMGEAEKASKDFSEALLHDPNHQAAYTRA
CHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHH
YALGMLKETPVDVSSPSSTATDYPLSLLEESVPVSVEPVEDSDGEQEPHPATVPLEPTSM
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
EGFFERANNRIQRGDLDGAISDYSKIIDTDPENSQAYYQRGQSLGALGESQAAMEDLNQA
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCHHHHHHHHHHHH
IHWARVHSLGLMRDFSGELSTTLETLKQDLKELSYQSPFAKTHPLPGTAADQMQQADPSA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCC
DDVIDVSSDQPDASGELKTVENSNSSITQPTSAKESAVTDVSIDTQSSEPESSSIFTQKE
CCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCC
PPAQVNPQPSSPQPQSPPPDAEIAAPTLERAIAQHTRAIEQNPLDADAFFNRGQSRALGG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC
DLQGAIEDYSRTIRLDPHNREAYVKRARCLSALGDETAAQADLNHVIRQSPKRPQPQPLK
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
TASAPPSTEFSQPQGAPSPAASTPPSPPQVDDATHSMASLFQQENEILQSTQTSQKSCTH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGNSPGNQFCIHCGASLSPLSRYSSDFSAPPPDSPPGEKVKPVASNRKQRLQEAEQYYDQ
CCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVALFRDGDRQGSLQSLSAGLKIFLEQREMQRYQQTLNFMQDVAHALNDTGEDEADPDDS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LLL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]