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The map label for this gene is yfcG [H]

Identifier: 158334409

GI number: 158334409

Start: 1208508

End: 1209140

Strand: Reverse

Name: yfcG [H]

Synonym: AM1_1230

Alternate gene names: 158334409

Gene position: 1209140-1208508 (Counterclockwise)

Preceding gene: 158334410

Following gene: 158334408

Centisome position: 18.59

GC content: 49.76

Gene sequence:

>633_bases
ATGATCCACCTCTACACTTACACAACCCCCAATGGACGCAAACCCGCCATTCTCCTGGAAGAGTTAGGGTTGCCCTATAC
CCTTCACAAAGTTGACTTGGGCAAGGGAGAACAGTTTAGTCCCGAATTTGTGGCCCTCAATCCCAATAGCAAAATTCCAG
CTATCAAAGACGAAGACACGGGCGTAACCGTCTTTGAGTCAGGTGCCATCCTCATTTACCTGGCGGAAAAAACTGAAAAA
TTATTACCTACTGATGCTGCGAGTCGGGCTCAAGTGATGGCATGGCTGATGTTCCAAATGGCAGGCGTCGGCCCGATGTT
TGGTCAACTGGGGCATTTCCGTCGATCCGCACCAGAACCGATTGAATATGCGATTAACCGCTATGAACAAGAAGCGTTAC
GCCTAGTGAAGGTTCTAAATCGGCAATTACAAGAGAGGGACTTTATCGCTGGCGAGTATTCCATTGCAGATATTGCTACC
TATCCCTGGGTGGCTGCCTATGAGTATGTGGGACTCAGTTTAGACCCCTTTCCCCATGTCCAAGCTTGGCTGGAGCGAGT
GGGGCAAAGACCTGCCGTGCAAACCGGAATGGCCATCTTAACCCCCGAGTTTAAGAGCGATTTAGCTCAGTAA

Upstream 100 bases:

>100_bases
CTTCCTGGAAAAAACAGGTAGCTGGCCTAAGACCGTCTAGCAGCCTGAATAGCGATGATTCTCGATCAACCCCCATGCGT
ACACTAGCAAGGCGCCTACC

Downstream 100 bases:

>100_bases
TTCATGAGAAAAACTTTCTTTCTAAGAACCCACAAACGCTGTTCTTTGAACCAAATGATAAGCTGAAGCCGACTACACTT
TCCTACTCATCTATGTCCGT

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIHLYTYTTPNGRKPAILLEELGLPYTLHKVDLGKGEQFSPEFVALNPNSKIPAIKDEDTGVTVFESGAILIYLAEKTEK
LLPTDAASRAQVMAWLMFQMAGVGPMFGQLGHFRRSAPEPIEYAINRYEQEALRLVKVLNRQLQERDFIAGEYSIADIAT
YPWVAAYEYVGLSLDPFPHVQAWLERVGQRPAVQTGMAILTPEFKSDLAQ

Sequences:

>Translated_210_residues
MIHLYTYTTPNGRKPAILLEELGLPYTLHKVDLGKGEQFSPEFVALNPNSKIPAIKDEDTGVTVFESGAILIYLAEKTEK
LLPTDAASRAQVMAWLMFQMAGVGPMFGQLGHFRRSAPEPIEYAINRYEQEALRLVKVLNRQLQERDFIAGEYSIADIAT
YPWVAAYEYVGLSLDPFPHVQAWLERVGQRPAVQTGMAILTPEFKSDLAQ
>Mature_210_residues
MIHLYTYTTPNGRKPAILLEELGLPYTLHKVDLGKGEQFSPEFVALNPNSKIPAIKDEDTGVTVFESGAILIYLAEKTEK
LLPTDAASRAQVMAWLMFQMAGVGPMFGQLGHFRRSAPEPIEYAINRYEQEALRLVKVLNRQLQERDFIAGEYSIADIAT
YPWVAAYEYVGLSLDPFPHVQAWLERVGQRPAVQTGMAILTPEFKSDLAQ

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=213, Percent_Identity=49.2957746478873, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082195, Length=215, Percent_Identity=45.5813953488372, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI87081789, Length=169, Percent_Identity=30.1775147928994, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1787923, Length=187, Percent_Identity=28.3422459893048, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=227, Percent_Identity=33.0396475770925, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571670, Length=170, Percent_Identity=32.3529411764706, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17933730, Length=196, Percent_Identity=31.1224489795918, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221378983, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646259, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864598, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864594, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922526, Length=201, Percent_Identity=31.8407960199005, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17864592, Length=189, Percent_Identity=30.6878306878307, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922160, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45549270, Length=186, Percent_Identity=29.5698924731183, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654979, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19922932, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646249, Length=161, Percent_Identity=29.1925465838509, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17864596, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646251, Length=199, Percent_Identity=28.1407035175879, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130115, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85725204, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737923, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23557; Mature: 23557

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHLYTYTTPNGRKPAILLEELGLPYTLHKVDLGKGEQFSPEFVALNPNSKIPAIKDEDT
CEEEEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCC
GVTVFESGAILIYLAEKTEKLLPTDAASRAQVMAWLMFQMAGVGPMFGQLGHFRRSAPEP
CEEEEECCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
IEYAINRYEQEALRLVKVLNRQLQERDFIAGEYSIADIATYPWVAAYEYVGLSLDPFPHV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHH
QAWLERVGQRPAVQTGMAILTPEFKSDLAQ
HHHHHHHCCCCCHHCCEEEECCHHHHHHCC
>Mature Secondary Structure
MIHLYTYTTPNGRKPAILLEELGLPYTLHKVDLGKGEQFSPEFVALNPNSKIPAIKDEDT
CEEEEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCC
GVTVFESGAILIYLAEKTEKLLPTDAASRAQVMAWLMFQMAGVGPMFGQLGHFRRSAPEP
CEEEEECCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
IEYAINRYEQEALRLVKVLNRQLQERDFIAGEYSIADIATYPWVAAYEYVGLSLDPFPHV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHH
QAWLERVGQRPAVQTGMAILTPEFKSDLAQ
HHHHHHHCCCCCHHCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]