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The map label for this gene is des6 [H]

Identifier: 158334254

GI number: 158334254

Start: 1042474

End: 1043583

Strand: Reverse

Name: des6 [H]

Synonym: AM1_1073

Alternate gene names: 158334254

Gene position: 1043583-1042474 (Counterclockwise)

Preceding gene: 158334255

Following gene: 158334249

Centisome position: 16.05

GC content: 46.04

Gene sequence:

>1110_bases
TTGACAAATCCACAAGTTACCTTTGCCAGGAACGTCGGGTTTAGGAAAGAATTGAGCCGACGGGTTAACGAATATTTCGC
CACAAACAATATCAGGCCTCGGGATAATCCAGCGATGTATTTCAAGACGCTAGTGATTACCGCTTGGACGCTGACCGCTT
GGAGCATCATCCTCTTTGGGCCACCCAATCTTGCCATCAAGATACTGGGATGTGTGGCCTTAGGAATGGGAGTGGCTGGC
TTCGGTATGAGCGTAGGCCATGATGCCAATCATGGTGGTTACTCGTCGAGTCCCCTGGTCAATCGGATTGTTGGCAGTTG
TTACGACGTTATTGGTGTCTCTAGCTTTTTATGGAAATTTCGCCATAATCAGCTCCATCATATCTACACCAATATTGAAG
GGTATGACAACGAAATCGAGGGAGATGGCGTCGTTCGTATGTCGCCCCATACGGACCATAAGCCTCACCACCGATGGCAA
CATTATTGGATTTGGTTTATTTATCCCTTTATTCCTATTTATTGGTATTTCAGAGATATTCAACGGTTTATCCGCAATAC
CCCCTATCAAACCAACACCCTTCCAACCAGGCAACCCATTGATTACGTCACCTTTTGGGTGGGGCGAATCATCGGTGTGT
CGTTCTTTATGGTCACCCCTTATTTGGTGGGATACTCTCCCTTACAGATAGTGTTGGGTTTCTGTATCGCCTATTGGACC
TATGGAGCCATTGTCTGTGAGATTTTTATGTTGGCCCATGTCATGGAGGGCATTGACTTCCCTAAGCCTGATCCCGAATC
GAACCAGATTGAAGATGAATGGGCAATTTTTCAGTTGAGAACAACTGCGGACTTTGCGCCTCGTAATCCTTTCTTAAACT
GGTATGTGGGTGGACTCAACTATCAAGCTGTACACCACTTATTCCCTCAAATCTGTCATATTCACTATCCCCAAATTGCT
CCAATCGTGGCTGAAGTTTGCCAAGAATTTGGCGTCAATTATATGGTGTACCCAACCTTTGCAAAGGCTATCGCTTCTAA
CTACAGATGGCTAAGGTTGATGGCAATTGGCGAAGAAGAGGTGAGTTACTCCCAAGCAACAACGTCCTGA

Upstream 100 bases:

>100_bases
TCCATCATTATTTGATTAAGATAACTATCTGAAATCCAATATTTCTCATTTAAGGGCAAGGTTTAGATATAAAATTCGAT
CAACTAAACAGGTATCGAAA

Downstream 100 bases:

>100_bases
TTCCGTTATCGATGCCCTTCAAGGTAGCTGAGAGATTAAGGATTCAGATGGCTTAAGCTAGCCAGCATATAAAAGCTGAT
ATAGAAAGAGTCGACTTCCC

Product: linoleoyl-CoA desaturase

Products: NA

Alternate protein names: Delta(6)-desaturase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTNPQVTFARNVGFRKELSRRVNEYFATNNIRPRDNPAMYFKTLVITAWTLTAWSIILFGPPNLAIKILGCVALGMGVAG
FGMSVGHDANHGGYSSSPLVNRIVGSCYDVIGVSSFLWKFRHNQLHHIYTNIEGYDNEIEGDGVVRMSPHTDHKPHHRWQ
HYWIWFIYPFIPIYWYFRDIQRFIRNTPYQTNTLPTRQPIDYVTFWVGRIIGVSFFMVTPYLVGYSPLQIVLGFCIAYWT
YGAIVCEIFMLAHVMEGIDFPKPDPESNQIEDEWAIFQLRTTADFAPRNPFLNWYVGGLNYQAVHHLFPQICHIHYPQIA
PIVAEVCQEFGVNYMVYPTFAKAIASNYRWLRLMAIGEEEVSYSQATTS

Sequences:

>Translated_369_residues
MTNPQVTFARNVGFRKELSRRVNEYFATNNIRPRDNPAMYFKTLVITAWTLTAWSIILFGPPNLAIKILGCVALGMGVAG
FGMSVGHDANHGGYSSSPLVNRIVGSCYDVIGVSSFLWKFRHNQLHHIYTNIEGYDNEIEGDGVVRMSPHTDHKPHHRWQ
HYWIWFIYPFIPIYWYFRDIQRFIRNTPYQTNTLPTRQPIDYVTFWVGRIIGVSFFMVTPYLVGYSPLQIVLGFCIAYWT
YGAIVCEIFMLAHVMEGIDFPKPDPESNQIEDEWAIFQLRTTADFAPRNPFLNWYVGGLNYQAVHHLFPQICHIHYPQIA
PIVAEVCQEFGVNYMVYPTFAKAIASNYRWLRLMAIGEEEVSYSQATTS
>Mature_368_residues
TNPQVTFARNVGFRKELSRRVNEYFATNNIRPRDNPAMYFKTLVITAWTLTAWSIILFGPPNLAIKILGCVALGMGVAGF
GMSVGHDANHGGYSSSPLVNRIVGSCYDVIGVSSFLWKFRHNQLHHIYTNIEGYDNEIEGDGVVRMSPHTDHKPHHRWQH
YWIWFIYPFIPIYWYFRDIQRFIRNTPYQTNTLPTRQPIDYVTFWVGRIIGVSFFMVTPYLVGYSPLQIVLGFCIAYWTY
GAIVCEIFMLAHVMEGIDFPKPDPESNQIEDEWAIFQLRTTADFAPRNPFLNWYVGGLNYQAVHHLFPQICHIHYPQIAP
IVAEVCQEFGVNYMVYPTFAKAIASNYRWLRLMAIGEEEVSYSQATTS

Specific function: Unknown

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13375616, Length=337, Percent_Identity=23.4421364985163, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17542396, Length=361, Percent_Identity=24.6537396121884, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: =1.14.19.3 [H]

Molecular weight: Translated: 42666; Mature: 42535

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPQVTFARNVGFRKELSRRVNEYFATNNIRPRDNPAMYFKTLVITAWTLTAWSIILFG
CCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEC
PPNLAIKILGCVALGMGVAGFGMSVGHDANHGGYSSSPLVNRIVGSCYDVIGVSSFLWKF
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RHNQLHHIYTNIEGYDNEIEGDGVVRMSPHTDHKPHHRWQHYWIWFIYPFIPIYWYFRDI
HCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHH
QRFIRNTPYQTNTLPTRQPIDYVTFWVGRIIGVSFFMVTPYLVGYSPLQIVLGFCIAYWT
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YGAIVCEIFMLAHVMEGIDFPKPDPESNQIEDEWAIFQLRTTADFAPRNPFLNWYVGGLN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCC
YQAVHHLFPQICHIHYPQIAPIVAEVCQEFGVNYMVYPTFAKAIASNYRWLRLMAIGEEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCEEEEEEECCHH
VSYSQATTS
HCCHHCCCC
>Mature Secondary Structure 
TNPQVTFARNVGFRKELSRRVNEYFATNNIRPRDNPAMYFKTLVITAWTLTAWSIILFG
CCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEC
PPNLAIKILGCVALGMGVAGFGMSVGHDANHGGYSSSPLVNRIVGSCYDVIGVSSFLWKF
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RHNQLHHIYTNIEGYDNEIEGDGVVRMSPHTDHKPHHRWQHYWIWFIYPFIPIYWYFRDI
HCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHH
QRFIRNTPYQTNTLPTRQPIDYVTFWVGRIIGVSFFMVTPYLVGYSPLQIVLGFCIAYWT
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YGAIVCEIFMLAHVMEGIDFPKPDPESNQIEDEWAIFQLRTTADFAPRNPFLNWYVGGLN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCC
YQAVHHLFPQICHIHYPQIAPIVAEVCQEFGVNYMVYPTFAKAIASNYRWLRLMAIGEEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCEEEEEEECCHH
VSYSQATTS
HCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8389613; 8905231 [H]