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The map label for this gene is nadA [H]

Identifier: 158334249

GI number: 158334249

Start: 1035416

End: 1036348

Strand: Reverse

Name: nadA [H]

Synonym: AM1_1068

Alternate gene names: 158334249

Gene position: 1036348-1035416 (Counterclockwise)

Preceding gene: 158334254

Following gene: 158334248

Centisome position: 15.93

GC content: 49.09

Gene sequence:

>933_bases
TTGTCAACGCCCCATGATTTAGTGGGAGCGATTAATGATCTAAAGAAAGATCTCAATGCCATTGTCTTGGCCCACTACTA
CCAAGAACCCGAGATCCAAGATGTCGCAGATTACTTAGGGGACTCTTTAGGCCTCTCTCGCCAAGCTGCCGACACCAATG
CTGAAGTCATTGTTTTCGCTGGCGTTCATTTCATGGCGGAGACGGCTAAAATTTTGAATCCAGATAAATTGGTATTGCTG
CCTGATGTGGACGCCGGTTGTTCTTTGGCAGATAGTTGTCCCCCTGACCAATTTGCCGCTTTCAAAGCTGCTCACCCCGA
TCACTTGGTGATTTCCTACATCAACTGTACGGCTGAAATTAAGGCTATGAGCGACATTATCTGCACTAGCTCCAACGCGG
TTCATATTGTCAATCAAATCCCTGCTGATCGACCGATTATTTTTGCTCCTGATCAAAATCTGGGTCGCTACGTGATGGCC
GAAACGGGGCGGGACTTGGTGCTCTGGCAAGGAAGCTGTATCGTTCATGAAACCTTTTCTGAACGGCGGTTGATTGAACT
CAAAACCAAGAATCCCCAAGCGGAGGTGATTGCTCACCCGGAATGCGAAGCTACCATTTTGAGACATGCCAGCTTTATTG
GTTCCACAACAGCTCTCCTGAAATATACGCAAACCAGTCCCCTAGACACCTTTATCGTGGCGACGGAATCCGGCATCTTG
CACCAGATGGAAAAGCAGGCCCCTGGCAAGCAATTTATTCCGGCGCCGCCTACAGGGAACTGTGCCTGTAATGAATGCCC
CTACATGCGCTTGAATACTTTGGAAAAACTGTATGTATCGATGCGCGATCGCAAACCGGAAATCACGATGCCGGCAGACA
TTCGCCAAGCTGCCCTCCATCCCATTCAGCGCATGCTAGAGATGAGTGTTTGA

Upstream 100 bases:

>100_bases
TTTGGTAAATTCAACTATAATTCTAGTTATCAACTATTAACCTTCGTCAAAAAATAGACGCTGACCAGTGTTTACAACTG
CCCTCCGCCCAAATGATGTT

Downstream 100 bases:

>100_bases
TGCCCGCCACAAATATAAGTGAAATCACGCTGTTTTGGGCAGAATAACCACGGTATTCTGCTAGTACAGTTTGGGAGAAC
ATCCTGATGATTCCGGCAAA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSTPHDLVGAINDLKKDLNAIVLAHYYQEPEIQDVADYLGDSLGLSRQAADTNAEVIVFAGVHFMAETAKILNPDKLVLL
PDVDAGCSLADSCPPDQFAAFKAAHPDHLVISYINCTAEIKAMSDIICTSSNAVHIVNQIPADRPIIFAPDQNLGRYVMA
ETGRDLVLWQGSCIVHETFSERRLIELKTKNPQAEVIAHPECEATILRHASFIGSTTALLKYTQTSPLDTFIVATESGIL
HQMEKQAPGKQFIPAPPTGNCACNECPYMRLNTLEKLYVSMRDRKPEITMPADIRQAALHPIQRMLEMSV

Sequences:

>Translated_310_residues
MSTPHDLVGAINDLKKDLNAIVLAHYYQEPEIQDVADYLGDSLGLSRQAADTNAEVIVFAGVHFMAETAKILNPDKLVLL
PDVDAGCSLADSCPPDQFAAFKAAHPDHLVISYINCTAEIKAMSDIICTSSNAVHIVNQIPADRPIIFAPDQNLGRYVMA
ETGRDLVLWQGSCIVHETFSERRLIELKTKNPQAEVIAHPECEATILRHASFIGSTTALLKYTQTSPLDTFIVATESGIL
HQMEKQAPGKQFIPAPPTGNCACNECPYMRLNTLEKLYVSMRDRKPEITMPADIRQAALHPIQRMLEMSV
>Mature_309_residues
STPHDLVGAINDLKKDLNAIVLAHYYQEPEIQDVADYLGDSLGLSRQAADTNAEVIVFAGVHFMAETAKILNPDKLVLLP
DVDAGCSLADSCPPDQFAAFKAAHPDHLVISYINCTAEIKAMSDIICTSSNAVHIVNQIPADRPIIFAPDQNLGRYVMAE
TGRDLVLWQGSCIVHETFSERRLIELKTKNPQAEVIAHPECEATILRHASFIGSTTALLKYTQTSPLDTFIVATESGILH
QMEKQAPGKQFIPAPPTGNCACNECPYMRLNTLEKLYVSMRDRKPEITMPADIRQAALHPIQRMLEMSV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=40, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34136; Mature: 34004

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPHDLVGAINDLKKDLNAIVLAHYYQEPEIQDVADYLGDSLGLSRQAADTNAEVIVFA
CCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GVHFMAETAKILNPDKLVLLPDVDAGCSLADSCPPDQFAAFKAAHPDHLVISYINCTAEI
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECHHHH
KAMSDIICTSSNAVHIVNQIPADRPIIFAPDQNLGRYVMAETGRDLVLWQGSCIVHETFS
HHHHHHEECCCCCEEEEECCCCCCCEEECCCCCCCCEEEECCCCEEEEEECCEEEEECCC
ERRLIELKTKNPQAEVIAHPECEATILRHASFIGSTTALLKYTQTSPLDTFIVATESGIL
CCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEEECCHHH
HQMEKQAPGKQFIPAPPTGNCACNECPYMRLNTLEKLYVSMRDRKPEITMPADIRQAALH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
PIQRMLEMSV
HHHHHHHHCC
>Mature Secondary Structure 
STPHDLVGAINDLKKDLNAIVLAHYYQEPEIQDVADYLGDSLGLSRQAADTNAEVIVFA
CCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GVHFMAETAKILNPDKLVLLPDVDAGCSLADSCPPDQFAAFKAAHPDHLVISYINCTAEI
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECHHHH
KAMSDIICTSSNAVHIVNQIPADRPIIFAPDQNLGRYVMAETGRDLVLWQGSCIVHETFS
HHHHHHEECCCCCEEEEECCCCCCCEEECCCCCCCCEEEECCCCEEEEEECCEEEEECCC
ERRLIELKTKNPQAEVIAHPECEATILRHASFIGSTTALLKYTQTSPLDTFIVATESGIL
CCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEEECCHHH
HQMEKQAPGKQFIPAPPTGNCACNECPYMRLNTLEKLYVSMRDRKPEITMPADIRQAALH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
PIQRMLEMSV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA