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The map label for this gene is kaiC

Identifier: 158334176

GI number: 158334176

Start: 964742

End: 966310

Strand: Reverse

Name: kaiC

Synonym: AM1_0992

Alternate gene names: 158334176

Gene position: 966310-964742 (Counterclockwise)

Preceding gene: 158334177

Following gene: 158334172

Centisome position: 14.86

GC content: 47.16

Gene sequence:

>1569_bases
ATGAAGAAAAGTAATTTATCTCAGTATAAAAAGAACGATAAGAATAAAGTCGAAGTAACCAAGATTTTGACTCGTATCGA
AGGCTTTGACGATATTAGTCATGGGGGCATACCACTGGGACGAACCACTCTGGTTAGTGGAACCTCTGGAACGGGCAAAA
CAATGTTCGCCATACAGTTCCTCTATCACGGCATTGTTCATTTTGATGACCCGGCTGTGTTTGTCACCTTTGAAGAGTCG
CCTAAAGATATCATCCAAAACGCCTTGAGCTTTGGATGGGATCTTCAACAACTCATGGACGATGGCAAGCTATTTATACT
CGATGCGTCTCCTGACCCAGAAGGGCAGGATATTGCAGGAGAATTCGATCTATCTGCCCTGATTGAGCGTATTCAGTATG
CCATCAGCAAGTATCAGGCCAAGCGAGTCGGCATTGACTCGGTGACCGCTATTTTTCAGCAGTATGATGCGGCGACAGTA
GTTCGGCGAGAGATTTTCAGGCTAACCGCTCGTCTCAAGCAAATTGGCGTGACGACGGTAATGACCACTGAACGGGTGGA
TGAATATGGTCCCGTGGCGCGATACGGTGTCGAAGAATTTGTCTCCGATAATGTCGTGATTGTTCGCAATGTCCTAGAAG
GGGAGCGACGCCGACGAACCTTAGAAATTTTGAAATTACGGGGCACCAGCCATATGAAGGGGGAGTATCCCTTCACAATT
ACGGATGATGGCATTAATATCTTCCCCCTCGGTGCCATGCGCCTCACCCAGCGATCTTCCAATGCTCGGGTCTCTTCTGG
GGTTCAAACGTTGGATGAGATGTGCGGAGGTGGCTTCTTTAAAGACTCAATTATCTTAGTCACGGGGGCGACAGGAACTG
GGAAAACCTTACTGGTCAGTAAGTTTCTAGAAGATGCCTGTAAGAATGGTGACCGCGCTATTCTGTTCGCCTATGAGGAA
TCTCGGGCTCAGCTATCCCGGAATGCTTACTCCTGGGGGATTGACTTTGAGGAGATGGAACAAAAAGGCCTCCTTAAAAT
CCTCTGTACCTATCCAGAATCGGCCGGGTTAGAAGATCACCTGCAGCAAATTAAATCCGAGATTGCTGAATTTAAACCAT
CGCGAATTTCGATTGACTCTCTTTCGGCCTTAGCGCGGGGGGTTAGCAACAATGCTTTCCGTCAGTTTGTGATTGGCGTA
ACGGGGTTTGCTAAGCAGGAAGAAATCACCGGCTTCTTTACCAATACAACGGATCACTTTTTAGGTTCCCACTCGATCAC
GGAATCCCATATTTCCACGATTACAGACACGATTTTGATGCTGCAATATGTGGAAATTCTGGGCGAAATGTCCCGGGCCA
TCAATGTCTTCAAGATGAGAGGCTCCTGGCATGATAAGGGAATTCGCGAATATTCCATTAGTCAGCATGGTCCAGAGATT
AAAAATGCGTTCCATAACTTTGAAGGCATTATCAGTGGTACGCCTACCCGGGTCTCCTTGGATGAGAAACGAGACCTATC
TCGGATTGTGCAAGATGTTAAAGGCTTAAGCGACGATGATCTGCTGTAG

Upstream 100 bases:

>100_bases
AACTTTCTGATGGCATTATGGAGTACTAGCCTACTTAATAAGGCGGCTTCAGCCCATATTCGACTTTAAAATTTTTTATT
CATTTTGATGTAGATGAACA

Downstream 100 bases:

>100_bases
CTAAGACTTAGGCATAAGGAAAGTCGGGTAATCCCAATTCGGCAACCCCCTGCTGTAATTGTTTTGCGGCAGCGATATTG
TTGTGTTGGCGATGGAGGGC

Product: circadian clock protein KaiC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKKSNLSQYKKNDKNKVEVTKILTRIEGFDDISHGGIPLGRTTLVSGTSGTGKTMFAIQFLYHGIVHFDDPAVFVTFEES
PKDIIQNALSFGWDLQQLMDDGKLFILDASPDPEGQDIAGEFDLSALIERIQYAISKYQAKRVGIDSVTAIFQQYDAATV
VRREIFRLTARLKQIGVTTVMTTERVDEYGPVARYGVEEFVSDNVVIVRNVLEGERRRRTLEILKLRGTSHMKGEYPFTI
TDDGINIFPLGAMRLTQRSSNARVSSGVQTLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFLEDACKNGDRAILFAYEE
SRAQLSRNAYSWGIDFEEMEQKGLLKILCTYPESAGLEDHLQQIKSEIAEFKPSRISIDSLSALARGVSNNAFRQFVIGV
TGFAKQEEITGFFTNTTDHFLGSHSITESHISTITDTILMLQYVEILGEMSRAINVFKMRGSWHDKGIREYSISQHGPEI
KNAFHNFEGIISGTPTRVSLDEKRDLSRIVQDVKGLSDDDLL

Sequences:

>Translated_522_residues
MKKSNLSQYKKNDKNKVEVTKILTRIEGFDDISHGGIPLGRTTLVSGTSGTGKTMFAIQFLYHGIVHFDDPAVFVTFEES
PKDIIQNALSFGWDLQQLMDDGKLFILDASPDPEGQDIAGEFDLSALIERIQYAISKYQAKRVGIDSVTAIFQQYDAATV
VRREIFRLTARLKQIGVTTVMTTERVDEYGPVARYGVEEFVSDNVVIVRNVLEGERRRRTLEILKLRGTSHMKGEYPFTI
TDDGINIFPLGAMRLTQRSSNARVSSGVQTLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFLEDACKNGDRAILFAYEE
SRAQLSRNAYSWGIDFEEMEQKGLLKILCTYPESAGLEDHLQQIKSEIAEFKPSRISIDSLSALARGVSNNAFRQFVIGV
TGFAKQEEITGFFTNTTDHFLGSHSITESHISTITDTILMLQYVEILGEMSRAINVFKMRGSWHDKGIREYSISQHGPEI
KNAFHNFEGIISGTPTRVSLDEKRDLSRIVQDVKGLSDDDLL
>Mature_522_residues
MKKSNLSQYKKNDKNKVEVTKILTRIEGFDDISHGGIPLGRTTLVSGTSGTGKTMFAIQFLYHGIVHFDDPAVFVTFEES
PKDIIQNALSFGWDLQQLMDDGKLFILDASPDPEGQDIAGEFDLSALIERIQYAISKYQAKRVGIDSVTAIFQQYDAATV
VRREIFRLTARLKQIGVTTVMTTERVDEYGPVARYGVEEFVSDNVVIVRNVLEGERRRRTLEILKLRGTSHMKGEYPFTI
TDDGINIFPLGAMRLTQRSSNARVSSGVQTLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFLEDACKNGDRAILFAYEE
SRAQLSRNAYSWGIDFEEMEQKGLLKILCTYPESAGLEDHLQQIKSEIAEFKPSRISIDSLSALARGVSNNAFRQFVIGV
TGFAKQEEITGFFTNTTDHFLGSHSITESHISTITDTILMLQYVEILGEMSRAINVFKMRGSWHDKGIREYSISQHGPEI
KNAFHNFEGIISGTPTRVSLDEKRDLSRIVQDVKGLSDDDLL

Specific function: Core component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by actin

COG id: COG0467

COG function: function code T; RecA-superfamily ATPases implicated in signal transduction

Gene ontology:
GO:0000166: Circadian clock protein kinase kaiC
GO:0000287: Circadian clock protein kinase kaiC
GO:0003677: Circadian clock protein kinase kaiC
GO:0004674: Circadian clock protein kinase kaiC
GO:0005524: Circadian clock protein kinase kaiC
GO:0006351: Circadian clock protein kinase kaiC
GO:0006355: Circadian clock protein kinase kaiC
GO:0016301: Circadian clock protein kinase kaiC
GO:0016310: Circadian clock protein kinase kaiC
GO:0016740: Circadian clock protein kinase kaiC
GO:0042752: Circadian clock protein kinase kaiC
GO:0046872: Circadian clock protein kinase kaiC
GO:0048511: Circadian clock protein kinase kaiC

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 kaiC domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KAIC_ACAM1 (Q6L8L1)

Other databases:

- EMBL:   AB120712
- EMBL:   CP000828
- RefSeq:   YP_001515348.1
- ProteinModelPortal:   Q6L8L1
- SMR:   Q6L8L1
- GeneID:   5679818
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_0992
- HOGENOM:   HBG519240
- OMA:   AFRQFVI
- ProtClustDB:   PRK09302
- BioCyc:   AMAR329726:AM1_0992-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01836
- InterPro:   IPR014774
- InterPro:   IPR013503
- InterPro:   IPR010624
- TIGRFAMs:   TIGR02655

Pfam domain/function: PF06745 KaiC

EC number: =2.7.11.1

Molecular weight: Translated: 58286; Mature: 58286

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS51146 KAIC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSNLSQYKKNDKNKVEVTKILTRIEGFDDISHGGIPLGRTTLVSGTSGTGKTMFAIQF
CCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
LYHGIVHFDDPAVFVTFEESPKDIIQNALSFGWDLQQLMDDGKLFILDASPDPEGQDIAG
HHHHHEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCC
EFDLSALIERIQYAISKYQAKRVGIDSVTAIFQQYDAATVVRREIFRLTARLKQIGVTTV
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MTTERVDEYGPVARYGVEEFVSDNVVIVRNVLEGERRRRTLEILKLRGTSHMKGEYPFTI
EEHHHHHHCCCHHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEE
TDDGINIFPLGAMRLTQRSSNARVSSGVQTLDEMCGGGFFKDSIILVTGATGTGKTLLVS
ECCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCHHHHHH
KFLEDACKNGDRAILFAYEESRAQLSRNAYSWGIDFEEMEQKGLLKILCTYPESAGLEDH
HHHHHHHCCCCEEEEEEEEHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEECCCCCCHHHH
LQQIKSEIAEFKPSRISIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDHF
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCCEEECCCHHHH
LGSHSITESHISTITDTILMLQYVEILGEMSRAINVFKMRGSWHDKGIREYSISQHGPEI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCHH
KNAFHNFEGIISGTPTRVSLDEKRDLSRIVQDVKGLSDDDLL
HHHHHCCCCEECCCCCEECCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKSNLSQYKKNDKNKVEVTKILTRIEGFDDISHGGIPLGRTTLVSGTSGTGKTMFAIQF
CCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
LYHGIVHFDDPAVFVTFEESPKDIIQNALSFGWDLQQLMDDGKLFILDASPDPEGQDIAG
HHHHHEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCC
EFDLSALIERIQYAISKYQAKRVGIDSVTAIFQQYDAATVVRREIFRLTARLKQIGVTTV
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MTTERVDEYGPVARYGVEEFVSDNVVIVRNVLEGERRRRTLEILKLRGTSHMKGEYPFTI
EEHHHHHHCCCHHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEE
TDDGINIFPLGAMRLTQRSSNARVSSGVQTLDEMCGGGFFKDSIILVTGATGTGKTLLVS
ECCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCHHHHHH
KFLEDACKNGDRAILFAYEESRAQLSRNAYSWGIDFEEMEQKGLLKILCTYPESAGLEDH
HHHHHHHCCCCEEEEEEEEHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEECCCCCCHHHH
LQQIKSEIAEFKPSRISIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDHF
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCCEEECCCHHHH
LGSHSITESHISTITDTILMLQYVEILGEMSRAINVFKMRGSWHDKGIREYSISQHGPEI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCHH
KNAFHNFEGIISGTPTRVSLDEKRDLSRIVQDVKGLSDDDLL
HHHHHCCCCEECCCCCEECCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA