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The map label for this gene is tadA [H]

Identifier: 158334126

GI number: 158334126

Start: 910213

End: 910665

Strand: Direct

Name: tadA [H]

Synonym: AM1_0942

Alternate gene names: 158334126

Gene position: 910213-910665 (Clockwise)

Preceding gene: 158334125

Following gene: 158334128

Centisome position: 14.0

GC content: 49.67

Gene sequence:

>453_bases
ATGACTCTAGACCTATTTATGGATGCAGCCATCCAAGAGGCTCAGCGGGGGTTAGCGGCTGGCGGAATTCCCATAGGATC
CGTAGTCGTCAAGAATGGGACTATCGTGGGTCGGGGTCATAATCTGAGGGTGCAACAAGGTAGTGCGATTTTACATGCAG
AGATGAGTGCTCTGGAAACCTTGGGTCGCCAACCTGCCATGTTTTACCAAGACGTTACGCTATACACCACCCTGTCACCG
TGCAGCATGTGTACAGGCGCTATTTTACTCTATAAAATCCCTCGCGTGGTCATAGGCGAGAATCACACCTTTATGGGAGA
AGAAGCCTTGCTAAAGTCCCGTGGGGTCAAAGTTACAGTCCTAGATCTTCCCCAGTGTCGCCAAATGATGCAGGCGTTTA
TTAAAGGAACTCCTCAACTTTGGTACGAGGATATTGGGGTTGAACAAGCCTGA

Upstream 100 bases:

>100_bases
AACGAAAGTAGCGTATAAACATCTCTTGTCTGATGGGTGAACTATTTACCCTCAAAGCATTCCCACACACTCTTGGGTTC
ATTTAGCACACAGTAAGACA

Downstream 100 bases:

>100_bases
AGCTCAACACAAGCCGAAACCAAAATCCCAGCCTCGAGATCATGAGCATCTTGATGCTGGGACGGGTTAAAGTCGAAATC
GATTTAGGCGTTAGGGGCAG

Product: cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTLDLFMDAAIQEAQRGLAAGGIPIGSVVVKNGTIVGRGHNLRVQQGSAILHAEMSALETLGRQPAMFYQDVTLYTTLSP
CSMCTGAILLYKIPRVVIGENHTFMGEEALLKSRGVKVTVLDLPQCRQMMQAFIKGTPQLWYEDIGVEQA

Sequences:

>Translated_150_residues
MTLDLFMDAAIQEAQRGLAAGGIPIGSVVVKNGTIVGRGHNLRVQQGSAILHAEMSALETLGRQPAMFYQDVTLYTTLSP
CSMCTGAILLYKIPRVVIGENHTFMGEEALLKSRGVKVTVLDLPQCRQMMQAFIKGTPQLWYEDIGVEQA
>Mature_149_residues
TLDLFMDAAIQEAQRGLAAGGIPIGSVVVKNGTIVGRGHNLRVQQGSAILHAEMSALETLGRQPAMFYQDVTLYTTLSPC
SMCTGAILLYKIPRVVIGENHTFMGEEALLKSRGVKVTVLDLPQCRQMMQAFIKGTPQLWYEDIGVEQA

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=130, Percent_Identity=33.0769230769231, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693172, Length=101, Percent_Identity=36.6336633663366, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=36.4583333333333, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=106, Percent_Identity=36.7924528301887, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=52.4475524475524, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16338; Mature: 16207

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLFMDAAIQEAQRGLAAGGIPIGSVVVKNGTIVGRGHNLRVQQGSAILHAEMSALET
CCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCEEEEECCCEEEHHHHHHHHH
LGRQPAMFYQDVTLYTTLSPCSMCTGAILLYKIPRVVIGENHTFMGEEALLKSRGVKVTV
HCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCEEEE
LDLPQCRQMMQAFIKGTPQLWYEDIGVEQA
ECCHHHHHHHHHHHCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TLDLFMDAAIQEAQRGLAAGGIPIGSVVVKNGTIVGRGHNLRVQQGSAILHAEMSALET
CHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCEEEEECCCEEEHHHHHHHHH
LGRQPAMFYQDVTLYTTLSPCSMCTGAILLYKIPRVVIGENHTFMGEEALLKSRGVKVTV
HCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCEEEE
LDLPQCRQMMQAFIKGTPQLWYEDIGVEQA
ECCHHHHHHHHHHHCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]