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The map label for this gene is cysH [H]

Identifier: 158334060

GI number: 158334060

Start: 852186

End: 853013

Strand: Direct

Name: cysH [H]

Synonym: AM1_0876

Alternate gene names: 158334060

Gene position: 852186-853013 (Clockwise)

Preceding gene: 158334058

Following gene: 158334061

Centisome position: 13.1

GC content: 48.55

Gene sequence:

>828_bases
ATGTCCTTAATTGATGCCTCCCCCTCTGAACAGAGCAGGGAACCCGATGGCCTCCGCACTTCAACTGGTTCCCCAGCCAT
GGAACCATTGAGCCAAACAATGGATTTAGAACAGATCAACCAACAATTTGATCAAGCATCTGCTGAGGATATTGTTGGTT
GGGCTGCCGAGTCCTTTGGGGACGGCTTAGTGATGAGTACTAGCTTTGGCATCCAAGCAGCGGTAATGCTGCATTTAGTC
ACGCAGGTTGTCCCTGATATTCCCGTTATTTGGATTGATACGGGATATCTGCCTGCACAAACCTATTTGTTTGCTGAACA
ACTAACAGAACGACTAGGGCTTAACCTCAAGGTGTATCAGTCTGCTATTAGCCCTGCCCGCATGGAAGCGCTCTACGGCA
AGCTTTGGGAATTTAATGATGTCAAAGCGTTCAATCAGTACGATCAGATGCGGAAAGTTGAACCCATGCAGCGAGCCTTA
CAGGAACTGCAGGCAACAGCATGGCTGGCTGGACTACGGAGTAAGCAAACCAGCTTCCGGCAGTCCTTGCGTCGAGTTGA
GCCTCAAGGCGATCTGTATAAAATTCTCCCCATCCTGAACTGGCACTCTAAAGATATTTACCAATATCTTCAAGCCCATG
ATTTGCCCTATCATCCATTCTTCGACTTAGGCTATACCACTGTCGGAGATTGGCATTCTAGCCGTCCAGTCGGTGCCGAT
GACGATAATGATCGAGCCACCCGGTTCCAGGGACTCAAGGAAGAATGTGGTTTGCACTTACCACAAACCCCTGAAGAGTC
ACAAAGTCTAGATTCCAGTTCTTTGTAG

Upstream 100 bases:

>100_bases
TCTATGAAGACTACATTTGTCTAGGATGAACGGTACAAATCATCAATCGCGGATAGAAAAAGCATGGTACTAATAGATTT
GAACCTGCGTTGGTATTGTG

Downstream 100 bases:

>100_bases
GCGTTTGCGATTCCAAAAAGCTAAGTTAGCAACGGCATGCTCCTGGGATGAACCATGGCCAGAATCCATAGTAAAAAATA
TCGGGCAGCCGCCAGAGCCA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSLIDASPSEQSREPDGLRTSTGSPAMEPLSQTMDLEQINQQFDQASAEDIVGWAAESFGDGLVMSTSFGIQAAVMLHLV
TQVVPDIPVIWIDTGYLPAQTYLFAEQLTERLGLNLKVYQSAISPARMEALYGKLWEFNDVKAFNQYDQMRKVEPMQRAL
QELQATAWLAGLRSKQTSFRQSLRRVEPQGDLYKILPILNWHSKDIYQYLQAHDLPYHPFFDLGYTTVGDWHSSRPVGAD
DDNDRATRFQGLKEECGLHLPQTPEESQSLDSSSL

Sequences:

>Translated_275_residues
MSLIDASPSEQSREPDGLRTSTGSPAMEPLSQTMDLEQINQQFDQASAEDIVGWAAESFGDGLVMSTSFGIQAAVMLHLV
TQVVPDIPVIWIDTGYLPAQTYLFAEQLTERLGLNLKVYQSAISPARMEALYGKLWEFNDVKAFNQYDQMRKVEPMQRAL
QELQATAWLAGLRSKQTSFRQSLRRVEPQGDLYKILPILNWHSKDIYQYLQAHDLPYHPFFDLGYTTVGDWHSSRPVGAD
DDNDRATRFQGLKEECGLHLPQTPEESQSLDSSSL
>Mature_274_residues
SLIDASPSEQSREPDGLRTSTGSPAMEPLSQTMDLEQINQQFDQASAEDIVGWAAESFGDGLVMSTSFGIQAAVMLHLVT
QVVPDIPVIWIDTGYLPAQTYLFAEQLTERLGLNLKVYQSAISPARMEALYGKLWEFNDVKAFNQYDQMRKVEPMQRALQ
ELQATAWLAGLRSKQTSFRQSLRRVEPQGDLYKILPILNWHSKDIYQYLQAHDLPYHPFFDLGYTTVGDWHSSRPVGADD
DNDRATRFQGLKEECGLHLPQTPEESQSLDSSSL

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=233, Percent_Identity=48.9270386266094, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6325425, Length=240, Percent_Identity=31.25, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 31033; Mature: 30902

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDASPSEQSREPDGLRTSTGSPAMEPLSQTMDLEQINQQFDQASAEDIVGWAAESFG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
DGLVMSTSFGIQAAVMLHLVTQVVPDIPVIWIDTGYLPAQTYLFAEQLTERLGLNLKVYQ
CCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHH
SAISPARMEALYGKLWEFNDVKAFNQYDQMRKVEPMQRALQELQATAWLAGLRSKQTSFR
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSLRRVEPQGDLYKILPILNWHSKDIYQYLQAHDLPYHPFFDLGYTTVGDWHSSRPVGAD
HHHHHCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCC
DDNDRATRFQGLKEECGLHLPQTPEESQSLDSSSL
CCCCHHHHHHCCHHHCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
SLIDASPSEQSREPDGLRTSTGSPAMEPLSQTMDLEQINQQFDQASAEDIVGWAAESFG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
DGLVMSTSFGIQAAVMLHLVTQVVPDIPVIWIDTGYLPAQTYLFAEQLTERLGLNLKVYQ
CCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHH
SAISPARMEALYGKLWEFNDVKAFNQYDQMRKVEPMQRALQELQATAWLAGLRSKQTSFR
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSLRRVEPQGDLYKILPILNWHSKDIYQYLQAHDLPYHPFFDLGYTTVGDWHSSRPVGAD
HHHHHCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCC
DDNDRATRFQGLKEECGLHLPQTPEESQSLDSSSL
CCCCHHHHHHCCHHHCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA