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The map label for this gene is macB [H]

Identifier: 158333838

GI number: 158333838

Start: 634789

End: 636006

Strand: Direct

Name: macB [H]

Synonym: AM1_0647

Alternate gene names: 158333838

Gene position: 634789-636006 (Clockwise)

Preceding gene: 158333837

Following gene: 158333839

Centisome position: 9.76

GC content: 48.52

Gene sequence:

>1218_bases
GTGGATATCCTCGAAAGCGTAAAAATGGCTTCAGCGACGCTAGTCGCCAACCGCCTGCGCAGTAGTTTGACGATGTTAGG
GATGATTATTGGCAATGCTTCTGTTATTGCCATGATCGCCGTGGGGCAAGGGGCCCAAAAGTATGCTTCCGGTCAGTTTG
AGTCCCTAGGACCCAACATTCTATTTATCGTTCCGGGAACTGATAAAGCCCGCCGACAGACCTTTGAAGTGCCCAAGACC
TTGGTTTGGGCGGATGCTAAAGCAATTAAAGAAGCGGTATCTGCAGTTCAATCTGTTATTCCTCAACTTCAGAATCAGTT
GACCACTGTTTACCAAGGGGCGAATACAACGGCCTTGGTGATGGGCACAACGGATGAATATCCAATTGTGCGGAACCATG
ATGTGGCTAAAGGTCGATTTCTTAGCCCGCAAGATATCCAGCGAGGCAATTTGGTGGCTGTATTAGGCACTGATCTGGCT
AAGCGCTTGGTGGGGTCTGAAAATCCAATTGGTAAGCGAATTCGGATTAAAAACCTCAATTTTGAAGTCGTTGGATTAAT
GGAGGAAAAGGGGTCTTTCCTTGGGAGTAGCCAAGATGATGTGATTTTTATTCCCATTTCAACGATGGCGAATCGGGTGG
TGGGATCTACATCTCCCTTTGGTACTGAGCTAACGTTTATCTCGGTCTCTGCTAAAGATGAAGCCAGTATTCCCTCAGCA
GAGTTTCAGATCCGTAATCTGTTGCGGATCCGCCACAAAATTATTGACGAAGATGATTTCACGATTCGGACTCAAAAGCA
GGCGTTGGAAATTATCGGCAATATCAGCGGTGCTTTGACGGTTATGTTGGCTGCAATTGCGAGTATTTCTCTGCTGGTAG
GTGGTATTGGCATTATGAATATCATGCTGGTGTCCGTGACGGAGCGGATTCAGGAAATTGGCCTCCGCAAAGCCATTGGA
GCCTCACAATCCGATATTTTGGTCCAATTTATGATCGAAGCGATTATTTTGTCTGCCGTAGGCGGCATGATTGGCACCTT
CGTTGGCGTGGGTGGCACGGTGATGGTCAGCAGCCTCACACCTTTGGAAACAGGTATTTCCGTTCCGGCTGTAATGTTGG
CTGTGGGGGTCTCAGGGGGAATTGGTCTGTTTTTTGGAGTCGTTCCGGCCCGACGGGCGGCTCAACTGGATCCAATTGTG
GCTCTGCGCAGTGCTTAA

Upstream 100 bases:

>100_bases
ATCAAACCCAGATTCTAGAGGGTGTAACCCCCGGTCAAAAAGTTTTTGAAACGTTTCCAGAAGGTCAAAAGCCCGAAGAT
TTAAAAGAGGAAGAGTAACC

Downstream 100 bases:

>100_bases
GGGAAGAATAAGTCTATGACCTCAACGCAGCCGCAAGCTCAATCCCTGACAGAAGGGAATCCAGATCAGGCCATTATTCG
CCTAGAGTCAATCACTAAGG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDILESVKMASATLVANRLRSSLTMLGMIIGNASVIAMIAVGQGAQKYASGQFESLGPNILFIVPGTDKARRQTFEVPKT
LVWADAKAIKEAVSAVQSVIPQLQNQLTTVYQGANTTALVMGTTDEYPIVRNHDVAKGRFLSPQDIQRGNLVAVLGTDLA
KRLVGSENPIGKRIRIKNLNFEVVGLMEEKGSFLGSSQDDVIFIPISTMANRVVGSTSPFGTELTFISVSAKDEASIPSA
EFQIRNLLRIRHKIIDEDDFTIRTQKQALEIIGNISGALTVMLAAIASISLLVGGIGIMNIMLVSVTERIQEIGLRKAIG
ASQSDILVQFMIEAIILSAVGGMIGTFVGVGGTVMVSSLTPLETGISVPAVMLAVGVSGGIGLFFGVVPARRAAQLDPIV
ALRSA

Sequences:

>Translated_405_residues
MDILESVKMASATLVANRLRSSLTMLGMIIGNASVIAMIAVGQGAQKYASGQFESLGPNILFIVPGTDKARRQTFEVPKT
LVWADAKAIKEAVSAVQSVIPQLQNQLTTVYQGANTTALVMGTTDEYPIVRNHDVAKGRFLSPQDIQRGNLVAVLGTDLA
KRLVGSENPIGKRIRIKNLNFEVVGLMEEKGSFLGSSQDDVIFIPISTMANRVVGSTSPFGTELTFISVSAKDEASIPSA
EFQIRNLLRIRHKIIDEDDFTIRTQKQALEIIGNISGALTVMLAAIASISLLVGGIGIMNIMLVSVTERIQEIGLRKAIG
ASQSDILVQFMIEAIILSAVGGMIGTFVGVGGTVMVSSLTPLETGISVPAVMLAVGVSGGIGLFFGVVPARRAAQLDPIV
ALRSA
>Mature_405_residues
MDILESVKMASATLVANRLRSSLTMLGMIIGNASVIAMIAVGQGAQKYASGQFESLGPNILFIVPGTDKARRQTFEVPKT
LVWADAKAIKEAVSAVQSVIPQLQNQLTTVYQGANTTALVMGTTDEYPIVRNHDVAKGRFLSPQDIQRGNLVAVLGTDLA
KRLVGSENPIGKRIRIKNLNFEVVGLMEEKGSFLGSSQDDVIFIPISTMANRVVGSTSPFGTELTFISVSAKDEASIPSA
EFQIRNLLRIRHKIIDEDDFTIRTQKQALEIIGNISGALTVMLAAIASISLLVGGIGIMNIMLVSVTERIQEIGLRKAIG
ASQSDILVQFMIEAIILSAVGGMIGTFVGVGGTVMVSSLTPLETGISVPAVMLAVGVSGGIGLFFGVVPARRAAQLDPIV
ALRSA

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=400, Percent_Identity=35, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42891; Mature: 42891

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILESVKMASATLVANRLRSSLTMLGMIIGNASVIAMIAVGQGAQKYASGQFESLGPNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCCCCCE
LFIVPGTDKARRQTFEVPKTLVWADAKAIKEAVSAVQSVIPQLQNQLTTVYQGANTTALV
EEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MGTTDEYPIVRNHDVAKGRFLSPQDIQRGNLVAVLGTDLAKRLVGSENPIGKRIRIKNLN
EECCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEECHHHHHHHCCCCCCCCCEEEEEECC
FEVVGLMEEKGSFLGSSQDDVIFIPISTMANRVVGSTSPFGTELTFISVSAKDEASIPSA
EEEEEEEHHCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCH
EFQIRNLLRIRHKIIDEDDFTIRTQKQALEIIGNISGALTVMLAAIASISLLVGGIGIMN
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERIQEIGLRKAIGASQSDILVQFMIEAIILSAVGGMIGTFVGVGGTVMVSSLT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PLETGISVPAVMLAVGVSGGIGLFFGVVPARRAAQLDPIVALRSA
CHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCHHHCCCC
>Mature Secondary Structure
MDILESVKMASATLVANRLRSSLTMLGMIIGNASVIAMIAVGQGAQKYASGQFESLGPNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCCCCCE
LFIVPGTDKARRQTFEVPKTLVWADAKAIKEAVSAVQSVIPQLQNQLTTVYQGANTTALV
EEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MGTTDEYPIVRNHDVAKGRFLSPQDIQRGNLVAVLGTDLAKRLVGSENPIGKRIRIKNLN
EECCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEECHHHHHHHCCCCCCCCCEEEEEECC
FEVVGLMEEKGSFLGSSQDDVIFIPISTMANRVVGSTSPFGTELTFISVSAKDEASIPSA
EEEEEEEHHCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCH
EFQIRNLLRIRHKIIDEDDFTIRTQKQALEIIGNISGALTVMLAAIASISLLVGGIGIMN
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERIQEIGLRKAIGASQSDILVQFMIEAIILSAVGGMIGTFVGVGGTVMVSSLT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PLETGISVPAVMLAVGVSGGIGLFFGVVPARRAAQLDPIVALRSA
CHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA