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The map label for this gene is thiL [H]

Identifier: 158333796

GI number: 158333796

Start: 594266

End: 595276

Strand: Direct

Name: thiL [H]

Synonym: AM1_0604

Alternate gene names: 158333796

Gene position: 594266-595276 (Clockwise)

Preceding gene: 158333795

Following gene: 158333797

Centisome position: 9.14

GC content: 47.58

Gene sequence:

>1011_bases
ATGGAAAAGAACAACTTAGGTGTCACTGTTGCCGAGTTGGGTGAGCAACAGGTATTACAACGGCTGTATCAGTTCTGTGA
AACCCGTATGGTGGGTGATGATGCTGCAGTACTCACACCGCGTGCAGGACATCTCCTAGTGGTGACGACGGATATGTTGG
TGGATGGGATTCATTTTTGCGATCGCACCACATCTCCCGCTGATGTAGGCTGGCGTTCTGCTGCTGCCAATTTATCTGAT
ATTGCGGCTATGGGAGCGAGTCCTTTGGGGCTGACCATTAGTCTGGGCTTACCTGAAACGTTACCAGTTAGCTGGCTTGA
TCAGTTTTATCAGGGGGTAGCTGATTGCTTAAACACTTATGGAACAGCCATTATTGGTGGAGATTTAAGTCGATCACCAG
TGATTACCGTGAGTATGACGGCGTTAGGGGAGGTCTCGCCCCATCAGCAAATTTTGCGTTCTACGGCTCAACCGGGAGAT
GCAATTGTGGTCACGGGGGTTCATGGTTCTGCTCGGGCGGGATTGGAGCTTTTACTCCACCCAGATTGGGGACAGGTATT
GAGTTCGGCAGAGTACTTAGCATTAAAACAGGCTCATCAGCGTCCTCAACCCCGATTAGATGTGATTCAAGCGCTCCAAC
AACTCACACCTGTTCCTAGAGTGACAGGAATGGATAGTAGTGACGGGTTGGCGGATGCCGTTTTGCAAATTTGTAGAGCG
AGCGGAGTGGGGGCTGAGATCCTGCAAACTCAAATTCCGATACCAATGAGCTTTAATAACACCCAAGTTTTAACCTCAGA
GCAAGCGATAGAATGGGCGCTTTATGGAGGGGAAGATTTTGAGTTAGTGCTATGTTTACCTTTACCTTCTGCTCAGGAAT
TGCTGAAGAGAATTAATCCAACCGCAATGATCATTGGTCAAATAGTTGCTGAAGGTGATGTTACTTTACTCAAGCCAAAT
GGGGAGGGGTTTTTGTTAGAAATGCAAAAAGGCTACCAACATTTCCAATAA

Upstream 100 bases:

>100_bases
CTCGGGTGATTAAAGGGGCTGAGAATCTCGTCTAAATTCACAAGCATCAACCACAATAGGCTTGGGAGCTGCTTCCAAGC
CTTTTTTTGATCAGGGACAG

Downstream 100 bases:

>100_bases
TTTTGTGCATTAGATCAAATTTGTACGGATGTTCATTTTTTTCGTTGCATCAAGTCAAATTCTTATGGCCAATTTTCCAA
TCCCAGATTCAATTCAGTAT

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MEKNNLGVTVAELGEQQVLQRLYQFCETRMVGDDAAVLTPRAGHLLVVTTDMLVDGIHFCDRTTSPADVGWRSAAANLSD
IAAMGASPLGLTISLGLPETLPVSWLDQFYQGVADCLNTYGTAIIGGDLSRSPVITVSMTALGEVSPHQQILRSTAQPGD
AIVVTGVHGSARAGLELLLHPDWGQVLSSAEYLALKQAHQRPQPRLDVIQALQQLTPVPRVTGMDSSDGLADAVLQICRA
SGVGAEILQTQIPIPMSFNNTQVLTSEQAIEWALYGGEDFELVLCLPLPSAQELLKRINPTAMIIGQIVAEGDVTLLKPN
GEGFLLEMQKGYQHFQ

Sequences:

>Translated_336_residues
MEKNNLGVTVAELGEQQVLQRLYQFCETRMVGDDAAVLTPRAGHLLVVTTDMLVDGIHFCDRTTSPADVGWRSAAANLSD
IAAMGASPLGLTISLGLPETLPVSWLDQFYQGVADCLNTYGTAIIGGDLSRSPVITVSMTALGEVSPHQQILRSTAQPGD
AIVVTGVHGSARAGLELLLHPDWGQVLSSAEYLALKQAHQRPQPRLDVIQALQQLTPVPRVTGMDSSDGLADAVLQICRA
SGVGAEILQTQIPIPMSFNNTQVLTSEQAIEWALYGGEDFELVLCLPLPSAQELLKRINPTAMIIGQIVAEGDVTLLKPN
GEGFLLEMQKGYQHFQ
>Mature_336_residues
MEKNNLGVTVAELGEQQVLQRLYQFCETRMVGDDAAVLTPRAGHLLVVTTDMLVDGIHFCDRTTSPADVGWRSAAANLSD
IAAMGASPLGLTISLGLPETLPVSWLDQFYQGVADCLNTYGTAIIGGDLSRSPVITVSMTALGEVSPHQQILRSTAQPGD
AIVVTGVHGSARAGLELLLHPDWGQVLSSAEYLALKQAHQRPQPRLDVIQALQQLTPVPRVTGMDSSDGLADAVLQICRA
SGVGAEILQTQIPIPMSFNNTQVLTSEQAIEWALYGGEDFELVLCLPLPSAQELLKRINPTAMIIGQIVAEGDVTLLKPN
GEGFLLEMQKGYQHFQ

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:
GO:0003824: Thiamine-monophosphate kinase, putative
GO:0016301: Thiamine-monophosphate kinase, putative
GO:0016310: Thiamine-monophosphate kinase, putative

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=331, Percent_Identity=35.0453172205438, Blast_Score=157, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36030; Mature: 36030

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNNLGVTVAELGEQQVLQRLYQFCETRMVGDDAAVLTPRAGHLLVVTTDMLVDGIHFC
CCCCCCCEEHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEEHHHHHHHHHHH
DRTTSPADVGWRSAAANLSDIAAMGASPLGLTISLGLPETLPVSWLDQFYQGVADCLNTY
CCCCCCCCCCHHHHHCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GTAIIGGDLSRSPVITVSMTALGEVSPHQQILRSTAQPGDAIVVTGVHGSARAGLELLLH
CCEEECCCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEC
PDWGQVLSSAEYLALKQAHQRPQPRLDVIQALQQLTPVPRVTGMDSSDGLADAVLQICRA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
SGVGAEILQTQIPIPMSFNNTQVLTSEQAIEWALYGGEDFELVLCLPLPSAQELLKRINP
CCCCHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHCCC
TAMIIGQIVAEGDVTLLKPNGEGFLLEMQKGYQHFQ
HHEEHHHHHCCCCEEEECCCCCEEEEEEHHCCCCCC
>Mature Secondary Structure
MEKNNLGVTVAELGEQQVLQRLYQFCETRMVGDDAAVLTPRAGHLLVVTTDMLVDGIHFC
CCCCCCCEEHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEEHHHHHHHHHHH
DRTTSPADVGWRSAAANLSDIAAMGASPLGLTISLGLPETLPVSWLDQFYQGVADCLNTY
CCCCCCCCCCHHHHHCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GTAIIGGDLSRSPVITVSMTALGEVSPHQQILRSTAQPGDAIVVTGVHGSARAGLELLLH
CCEEECCCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEC
PDWGQVLSSAEYLALKQAHQRPQPRLDVIQALQQLTPVPRVTGMDSSDGLADAVLQICRA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
SGVGAEILQTQIPIPMSFNNTQVLTSEQAIEWALYGGEDFELVLCLPLPSAQELLKRINP
CCCCHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHCCC
TAMIIGQIVAEGDVTLLKPNGEGFLLEMQKGYQHFQ
HHEEHHHHHCCCCEEEECCCCCEEEEEEHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA