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The map label for this gene is trxB [H]

Identifier: 158333658

GI number: 158333658

Start: 438279

End: 439277

Strand: Direct

Name: trxB [H]

Synonym: AM1_0460

Alternate gene names: 158333658

Gene position: 438279-439277 (Clockwise)

Preceding gene: 158333657

Following gene: 158333659

Centisome position: 6.74

GC content: 45.95

Gene sequence:

>999_bases
ATGAAGCTCAATAGAACCAACCTTGAACAACGTTTAGACCATCTCTATGATGTCATTGTCGTGGGGGGTGGGGCAGGCGG
TCTATCTGCAGGAATCTATCTACAGCGATTTCGCCTCTCCAGTCTGATTATTGACAAAGGTAAGGCTCGTTCATCCTGGA
TGCAGTCATTACACAACTATTTGGGACTGCCACCGGATACGTCCGGTCGAAAACTACTGCAACAGGGAAAAAAACACTAT
GACTCCTTGGCGGGAGACTTCCTCGATGGTTATGTCGAAGAGGTCACTGACGCGGAGAACATCTTTGAGATCCAAGTTAA
GGTGGGTCGTCAAAACAGCCGCAACGTCAAGTTTTATTCTAAATATTTGATCGTCGCCAGCGGCATTATTGATCATCTGC
TGCCTTTGGAAGATATGCAAAATGTTTATGACTATGCGGGGTATAACCTTCATGTCTGCATGGTTTGTGATGGCTATGAA
ATGACCGACAAACTTTGTGGCTTCTTTGCAGGTAGTGAAGCCAGCATTGAAGAAATGGTGTTTAACCTCAGTTGGTTTAC
GCCCAAGATCACCATCTTTACCCATGGCCTATTTGAGGTGAGTGGTCAGATGCGCAGCCAATTACAAGAGTATGGATATC
GTTTGGTAGAAACCCCCATCCAGAAATTTTTAGGTGAGAACCACCAAATGACGGGTGTAGAGTTGGTGAACGGTTCAGTC
ATTGAATTGGAAACGGGGCTAATCTCAATGGGGGCTCGCTATCACAACACCTATCTTCAGGAATTGAGCTTAGAGATGAA
AGGCGGTAACTTAGTCACTGATAAATTGGGTCGCACCTCCCATCCTCGGATTTTTGCGATCGGAGATTTAAAGGTTGGTC
TGAATCAAGTGGTAGTCGCAGCAGGGGATGGTGCTTTGGCCGCCACTCAGATTTGGAGAGAGATTCGCAAAGATATTGGT
CCTAGAAAATGGCTGATGAATCTCAAGCTTCCGACATAG

Upstream 100 bases:

>100_bases
GCAGATCATTCCCGTCGCTGAGTTGATGCAAGAGCTAACAGCATCCCTTTAACTCCGTTCCTTATCCTTAGTCCGATTGC
ACTCATAACTAAAGAGACCG

Downstream 100 bases:

>100_bases
ATGGCTTGAATAAATTGTCGTCTCAAGGTACTGGTTAAGGCCATACTGGTTGAACCAAGACTCATTTATCGATTTTGACA
GGCGAGCAATGATTAATCTG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKLNRTNLEQRLDHLYDVIVVGGGAGGLSAGIYLQRFRLSSLIIDKGKARSSWMQSLHNYLGLPPDTSGRKLLQQGKKHY
DSLAGDFLDGYVEEVTDAENIFEIQVKVGRQNSRNVKFYSKYLIVASGIIDHLLPLEDMQNVYDYAGYNLHVCMVCDGYE
MTDKLCGFFAGSEASIEEMVFNLSWFTPKITIFTHGLFEVSGQMRSQLQEYGYRLVETPIQKFLGENHQMTGVELVNGSV
IELETGLISMGARYHNTYLQELSLEMKGGNLVTDKLGRTSHPRIFAIGDLKVGLNQVVVAAGDGALAATQIWREIRKDIG
PRKWLMNLKLPT

Sequences:

>Translated_332_residues
MKLNRTNLEQRLDHLYDVIVVGGGAGGLSAGIYLQRFRLSSLIIDKGKARSSWMQSLHNYLGLPPDTSGRKLLQQGKKHY
DSLAGDFLDGYVEEVTDAENIFEIQVKVGRQNSRNVKFYSKYLIVASGIIDHLLPLEDMQNVYDYAGYNLHVCMVCDGYE
MTDKLCGFFAGSEASIEEMVFNLSWFTPKITIFTHGLFEVSGQMRSQLQEYGYRLVETPIQKFLGENHQMTGVELVNGSV
IELETGLISMGARYHNTYLQELSLEMKGGNLVTDKLGRTSHPRIFAIGDLKVGLNQVVVAAGDGALAATQIWREIRKDIG
PRKWLMNLKLPT
>Mature_332_residues
MKLNRTNLEQRLDHLYDVIVVGGGAGGLSAGIYLQRFRLSSLIIDKGKARSSWMQSLHNYLGLPPDTSGRKLLQQGKKHY
DSLAGDFLDGYVEEVTDAENIFEIQVKVGRQNSRNVKFYSKYLIVASGIIDHLLPLEDMQNVYDYAGYNLHVCMVCDGYE
MTDKLCGFFAGSEASIEEMVFNLSWFTPKITIFTHGLFEVSGQMRSQLQEYGYRLVETPIQKFLGENHQMTGVELVNGSV
IELETGLISMGARYHNTYLQELSLEMKGGNLVTDKLGRTSHPRIFAIGDLKVGLNQVVVAAGDGALAATQIWREIRKDIG
PRKWLMNLKLPT

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=22.8571428571429, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 37252; Mature: 37252

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNRTNLEQRLDHLYDVIVVGGGAGGLSAGIYLQRFRLSSLIIDKGKARSSWMQSLHNY
CCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LGLPPDTSGRKLLQQGKKHYDSLAGDFLDGYVEEVTDAENIFEIQVKVGRQNSRNVKFYS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHH
KYLIVASGIIDHLLPLEDMQNVYDYAGYNLHVCMVCDGYEMTDKLCGFFAGSEASIEEMV
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHH
FNLSWFTPKITIFTHGLFEVSGQMRSQLQEYGYRLVETPIQKFLGENHQMTGVELVNGSV
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEECCCE
IELETGLISMGARYHNTYLQELSLEMKGGNLVTDKLGRTSHPRIFAIGDLKVGLNQVVVA
EEEECCHHHHCCHHHHHHHHHHHEEECCCEEEHHHCCCCCCCEEEEEECEEECCCEEEEE
AGDGALAATQIWREIRKDIGPRKWLMNLKLPT
ECCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure
MKLNRTNLEQRLDHLYDVIVVGGGAGGLSAGIYLQRFRLSSLIIDKGKARSSWMQSLHNY
CCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LGLPPDTSGRKLLQQGKKHYDSLAGDFLDGYVEEVTDAENIFEIQVKVGRQNSRNVKFYS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHH
KYLIVASGIIDHLLPLEDMQNVYDYAGYNLHVCMVCDGYEMTDKLCGFFAGSEASIEEMV
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHH
FNLSWFTPKITIFTHGLFEVSGQMRSQLQEYGYRLVETPIQKFLGENHQMTGVELVNGSV
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEECCCE
IELETGLISMGARYHNTYLQELSLEMKGGNLVTDKLGRTSHPRIFAIGDLKVGLNQVVVA
EEEECCHHHHCCHHHHHHHHHHHEEECCCEEEHHHCCCCCCCEEEEEECEEECCCEEEEE
AGDGALAATQIWREIRKDIGPRKWLMNLKLPT
ECCCCHHHHHHHHHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]