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The map label for this gene is rfbC [H]

Identifier: 158333602

GI number: 158333602

Start: 377484

End: 378047

Strand: Reverse

Name: rfbC [H]

Synonym: AM1_0403

Alternate gene names: 158333602

Gene position: 378047-377484 (Counterclockwise)

Preceding gene: 158333603

Following gene: 158333601

Centisome position: 5.81

GC content: 46.99

Gene sequence:

>564_bases
GTGAATGTGATAGAAACTCCTTTGCCGGGTGTTTTAGTGATTGAACCTCGTGTATTTTCGGACCAACGGGGCTTTTTCTT
GGAAACTTATCATCGCCAACGGTATACAGCATCTGGTATTGATGAGATTTTTGTTCAAGACAATCATTCTCGGTCTGCCC
ATGGAACATTGCGAGGCCTCCACTTTCAGCTGAAGTCTCCCCAAGGGAAATTAGTCAGGGTCAGTGCGGGGGAGGTTTTT
GATGTAGCTGTTGATATACGACGGGGGTCACCCTATTTTGGTCAGTGGTTTGGGGAGTATCTCTCTGGTGAAAACAATAA
ACAGATGTATGTTCCACCTGGTTTTGCCCATGGCTTTTGTGTCTTAAGCGAGACGGCAGATTTTATGTATAAATGCAGTG
ATTTTTACGACCCAACGGATGAGCAAGGGGTGGCTTGGGATGATCCGGCCTTGGCCATAGACTGGCCCATCGACCAGCCG
ATCCTATCGAAGAAAGATGCTGCGTTACCTAAAATGTCGGAGCTGATGGATTGTTTGCCTCGGTTTGCAATGTCTCAGGT
TTAG

Upstream 100 bases:

>100_bases
ATATCTCAGCTGCTCAAGTTAAAGAATTAAGTCGAGATTTGTGCAAGAACAGTTATGGAGAGTATCTCCTGAGAGTGCTG
GAAGAGGGAGGTCAACCCCT

Downstream 100 bases:

>100_bases
CGGATGAGGATCGAATGGGTATTAAGGCCCAAGTGAAGGGACAGAAATCGTGAACTGACGATGGTGTCTGTGAACTCTTT
GCGGCCATACCGTATCCAAT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNVIETPLPGVLVIEPRVFSDQRGFFLETYHRQRYTASGIDEIFVQDNHSRSAHGTLRGLHFQLKSPQGKLVRVSAGEVF
DVAVDIRRGSPYFGQWFGEYLSGENNKQMYVPPGFAHGFCVLSETADFMYKCSDFYDPTDEQGVAWDDPALAIDWPIDQP
ILSKKDAALPKMSELMDCLPRFAMSQV

Sequences:

>Translated_187_residues
MNVIETPLPGVLVIEPRVFSDQRGFFLETYHRQRYTASGIDEIFVQDNHSRSAHGTLRGLHFQLKSPQGKLVRVSAGEVF
DVAVDIRRGSPYFGQWFGEYLSGENNKQMYVPPGFAHGFCVLSETADFMYKCSDFYDPTDEQGVAWDDPALAIDWPIDQP
ILSKKDAALPKMSELMDCLPRFAMSQV
>Mature_187_residues
MNVIETPLPGVLVIEPRVFSDQRGFFLETYHRQRYTASGIDEIFVQDNHSRSAHGTLRGLHFQLKSPQGKLVRVSAGEVF
DVAVDIRRGSPYFGQWFGEYLSGENNKQMYVPPGFAHGFCVLSETADFMYKCSDFYDPTDEQGVAWDDPALAIDWPIDQP
ILSKKDAALPKMSELMDCLPRFAMSQV

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:
GO:0008830: dTDP-4-dehydrorhamnose 3,5-epimerase
GO:0009103: dTDP-4-dehydrorhamnose 3,5-epimerase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=179, Percent_Identity=50.8379888268156, Blast_Score=177, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17550412, Length=170, Percent_Identity=48.8235294117647, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21159; Mature: 21159

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIETPLPGVLVIEPRVFSDQRGFFLETYHRQRYTASGIDEIFVQDNHSRSAHGTLRGL
CCCCCCCCCCEEEECCEECCCCCCCEEEHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
HFQLKSPQGKLVRVSAGEVFDVAVDIRRGSPYFGQWFGEYLSGENNKQMYVPPGFAHGFC
EEEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEE
VLSETADFMYKCSDFYDPTDEQGVAWDDPALAIDWPIDQPILSKKDAALPKMSELMDCLP
EEEHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCHHCCCCCCCCHHHHHHHHHH
RFAMSQV
HHHHHCC
>Mature Secondary Structure
MNVIETPLPGVLVIEPRVFSDQRGFFLETYHRQRYTASGIDEIFVQDNHSRSAHGTLRGL
CCCCCCCCCCEEEECCEECCCCCCCEEEHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
HFQLKSPQGKLVRVSAGEVFDVAVDIRRGSPYFGQWFGEYLSGENNKQMYVPPGFAHGFC
EEEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEE
VLSETADFMYKCSDFYDPTDEQGVAWDDPALAIDWPIDQPILSKKDAALPKMSELMDCLP
EEEHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCHHCCCCCCCCHHHHHHHHHH
RFAMSQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]