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The map label for this gene is cah [H]

Identifier: 158333321

GI number: 158333321

Start: 97763

End: 98467

Strand: Reverse

Name: cah [H]

Synonym: AM1_0091

Alternate gene names: 158333321

Gene position: 98467-97763 (Counterclockwise)

Preceding gene: 158333322

Following gene: 158333320

Centisome position: 1.51

GC content: 47.8

Gene sequence:

>705_bases
TTGGCAATACCTGCGATCGCAACACCGATCTGGAGCTATGAAGGCACATCTGATCCCGGGCATTGGTCAGAATTACAGTC
CGATTATTCCCTCTGTGCAACGGGGCAGTCACAGTCACCGATCAACTTGCGATCGCAAGATCTCAGCAGCAATCACGAAA
CCTTAAATGTGGACTATCACGCTTCTCCATTGGATGAAGTCAATAATGGGCGCACAGTAACCGTAAACTACGCCGCCGGG
AATACCCTAACCGTGAATAATCAAACCTATGAATTAGTCCAGTTTCATTTCCACGCTCCGAGTGAACACCGGATTAACAA
TAAATCCAGCGCCATGGAAATGCACCTGGTGCATAAAAATGCAGCAGATGAGTTAGCGGTGCTGGGGGTCATGATTCAGC
CAGGGGCTGCTAATCCCTTATTGGATGAGATTTGGGAGAATATGCCTGCGGTGGAAGAAGAGAATGCACCTAATTTAGAG
ATTGACGTTCGTTCGCTACTGCCCCGCGATCGCAGTTTTTACCATTACCAAGGATCCCTGACGACTCCCCCCTGTAGTGA
GTCCGTCAATTGGGCCATCCTTAAGCAACCCATTCAAGCCTCTCGCCAGCAAATCAGTACCTTTAAGTCCCAGTTTCACG
CAAATGCTAGACCAGTTCAAGCTCTCAATAACCGATCCATTCAGTTTTCTGATTCTTTAAGTTAA

Upstream 100 bases:

>100_bases
TTAGAGTCAAAAAAGCTTGCATTACCCTCTACGTACTATGCACCACTTCAACAAGTTTTTTCCTCGTCTCATCAGTTTGA
TTTGTCTAGCTTGGATGCTA

Downstream 100 bases:

>100_bases
TTGAACATCCTCAACCAACCTAACGGAAATGTCCCTAAGCTAACGGAACAATAAGCACCATCTCTGTAATTAAGATGAAT
CGCTTCAAAAGGGGGACAAA

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAIPAIATPIWSYEGTSDPGHWSELQSDYSLCATGQSQSPINLRSQDLSSNHETLNVDYHASPLDEVNNGRTVTVNYAAG
NTLTVNNQTYELVQFHFHAPSEHRINNKSSAMEMHLVHKNAADELAVLGVMIQPGAANPLLDEIWENMPAVEEENAPNLE
IDVRSLLPRDRSFYHYQGSLTTPPCSESVNWAILKQPIQASRQQISTFKSQFHANARPVQALNNRSIQFSDSLS

Sequences:

>Translated_234_residues
MAIPAIATPIWSYEGTSDPGHWSELQSDYSLCATGQSQSPINLRSQDLSSNHETLNVDYHASPLDEVNNGRTVTVNYAAG
NTLTVNNQTYELVQFHFHAPSEHRINNKSSAMEMHLVHKNAADELAVLGVMIQPGAANPLLDEIWENMPAVEEENAPNLE
IDVRSLLPRDRSFYHYQGSLTTPPCSESVNWAILKQPIQASRQQISTFKSQFHANARPVQALNNRSIQFSDSLS
>Mature_233_residues
AIPAIATPIWSYEGTSDPGHWSELQSDYSLCATGQSQSPINLRSQDLSSNHETLNVDYHASPLDEVNNGRTVTVNYAAGN
TLTVNNQTYELVQFHFHAPSEHRINNKSSAMEMHLVHKNAADELAVLGVMIQPGAANPLLDEIWENMPAVEEENAPNLEI
DVRSLLPRDRSFYHYQGSLTTPPCSESVNWAILKQPIQASRQQISTFKSQFHANARPVQALNNRSIQFSDSLS

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Homo sapiens, GI258679498, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI192447434, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI192447432, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI192447430, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI4502517, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI4557395, Length=258, Percent_Identity=32.9457364341085, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI4885101, Length=259, Percent_Identity=33.5907335907336, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI38348436, Length=262, Percent_Identity=31.6793893129771, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4885099, Length=261, Percent_Identity=29.1187739463602, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI6005723, Length=245, Percent_Identity=31.0204081632653, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI45935383, Length=256, Percent_Identity=29.296875, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4502515, Length=256, Percent_Identity=29.296875, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI62240989, Length=203, Percent_Identity=33.4975369458128, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI4502521, Length=232, Percent_Identity=31.4655172413793, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI70167127, Length=257, Percent_Identity=30.3501945525292, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI6912284, Length=259, Percent_Identity=28.1853281853282, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI169636420, Length=259, Percent_Identity=30.5019305019305, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI130979954, Length=280, Percent_Identity=25, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI130979679, Length=280, Percent_Identity=25, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI9910366, Length=280, Percent_Identity=25, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI194097398, Length=275, Percent_Identity=28.7272727272727, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI22027500, Length=243, Percent_Identity=28.3950617283951, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4502519, Length=175, Percent_Identity=30.8571428571429, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI9951923, Length=273, Percent_Identity=24.9084249084249, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568715, Length=245, Percent_Identity=33.8775510204082, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71995280, Length=266, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17569163, Length=230, Percent_Identity=29.5652173913043, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17569165, Length=229, Percent_Identity=29.6943231441048, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24645604, Length=231, Percent_Identity=31.6017316017316, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21358169, Length=261, Percent_Identity=29.5019157088123, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17737413, Length=235, Percent_Identity=31.9148936170213, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650523, Length=244, Percent_Identity=30.7377049180328, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161079350, Length=263, Percent_Identity=30.4182509505703, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18858185, Length=267, Percent_Identity=25.8426966292135, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI221329761, Length=259, Percent_Identity=27.4131274131274, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161079354, Length=287, Percent_Identity=28.9198606271777, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24651619, Length=239, Percent_Identity=28.0334728033473, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116008410, Length=257, Percent_Identity=29.5719844357977, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573346, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18857983, Length=206, Percent_Identity=28.1553398058252, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26025; Mature: 25894

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPAIATPIWSYEGTSDPGHWSELQSDYSLCATGQSQSPINLRSQDLSSNHETLNVDYH
CCCCCCCCCEECCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEC
ASPLDEVNNGRTVTVNYAAGNTLTVNNQTYELVQFHFHAPSEHRINNKSSAMEMHLVHKN
CCCHHHCCCCCEEEEEEECCCEEEECCCEEEEEEEEECCCCCCCCCCCCHHEEEEEECCC
AADELAVLGVMIQPGAANPLLDEIWENMPAVEEENAPNLEIDVRSLLPRDRSFYHYQGSL
CHHCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCCCCEEEEECCC
TTPPCSESVNWAILKQPIQASRQQISTFKSQFHANARPVQALNNRSIQFSDSLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCC
>Mature Secondary Structure 
AIPAIATPIWSYEGTSDPGHWSELQSDYSLCATGQSQSPINLRSQDLSSNHETLNVDYH
CCCCCCCCEECCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEC
ASPLDEVNNGRTVTVNYAAGNTLTVNNQTYELVQFHFHAPSEHRINNKSSAMEMHLVHKN
CCCHHHCCCCCEEEEEEECCCEEEECCCEEEEEEEEECCCCCCCCCCCCHHEEEEEECCC
AADELAVLGVMIQPGAANPLLDEIWENMPAVEEENAPNLEIDVRSLLPRDRSFYHYQGSL
CHHCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCCCCEEEEECCC
TTPPCSESVNWAILKQPIQASRQQISTFKSQFHANARPVQALNNRSIQFSDSLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9811652 [H]