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The map label for this gene is cph2 [H]

Identifier: 158333299

GI number: 158333299

Start: 70390

End: 71421

Strand: Direct

Name: cph2 [H]

Synonym: AM1_0069

Alternate gene names: 158333299

Gene position: 70390-71421 (Clockwise)

Preceding gene: 158333298

Following gene: 158333300

Centisome position: 1.08

GC content: 46.61

Gene sequence:

>1032_bases
ATGCCTGATTCCCCCAAACCTTCAAATATTCTCATCGTCGATGATGTGCCAACGAATCTCACCATTTTGGCTCAGACACT
CAGAGATCAGGGGTTTACAGTTTGGGTCGCCACTAGTGGGAATGCTGCCTTAAAGCAGTTAGCTCATGGTTTACCTGATC
TGATTTTGTTAGATATCCAAATGCCGGGAATGAATGGCTTGGAAACTTGTGCAAAATTAAAAGCCGATCTTCGTACCCAG
GATATTCCCGTTATTTTCATGTCTGCTCTAAGTGAGCAGGCGAATAAAGTTGAGGGATTGTCCTTAGGAGCGGTTGATTA
CATCACCAAGCCTTTCCAGGAAGCCGAAGTCCTCGCCAGAGTGAAAGTGCATTTGAGCATTCGAGAGCTGACGCAGAATC
TGCAGCGGGAAATTGAAGAGCGTAAACGAGTTGAAGCAGAACTCGCAAAGGCAAATGCCTCTTTGCATCGCCTAGCCCAC
ATTGATGGCTTAACTCAAGTGGCCAACCGCTATCGGTTTGATCAAGATATGGAGCAAGTTTGGCGGCGATTACAACGTGA
TCATGAACCCTTATCGCTCATTTTATGCGACGTTGATTATTTCAAATTGTTTAACGATCACTATGGTCATCAGGTTGGAG
ATGACTGCTTAAGGCAAGTCGCCCTTGCCATCCAAAAGGCCGTTCATCGCCCGGACGATCTGGTTGCTCGCTATGGGGGC
GAAGAATTTGCGATCGTTTTGCCTTCAACCCATGCCCAAGGCGCAGAACAAGTTGCCCTGGGCATTCTCAGTAAGATTGC
AGAACTCAACATTCCCCATGAGTTTTCCACTGTTAGCCCTCAAATCACCCTAAGTTTAGGAATTGCCACCGTTATTCCTA
AATCTGAGCAGTCGTTGGATGGCTTAATTGAATTAACAGACAAAGCGCTATATCGGGCTAAGGAAGAAGGTAGAAATACT
TATTGTCACCATGACTGTTCACAATCCCCTCCCTCTCTAAGCTGCTCGCCATCTCCCCTATCCCTCCATTAG

Upstream 100 bases:

>100_bases
TTACCCTTCACAATGGAAAAGTCAAACTATCCTGTTTTTGATATAAATTTATCTGGATGTGCCGTTAGCCTCCACTAGTC
CAGTCTTACTTAGCAAGGCG

Downstream 100 bases:

>100_bases
GAGCAGTATTCTGTGAAGGCGAGCTGACCGCCAAAAATATGTTCAGATAGGTAAAGCCTAAACCTGGTGCCCAGCAAGGT
GTATCTTAGGTGAGATCTTT

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPDSPKPSNILIVDDVPTNLTILAQTLRDQGFTVWVATSGNAALKQLAHGLPDLILLDIQMPGMNGLETCAKLKADLRTQ
DIPVIFMSALSEQANKVEGLSLGAVDYITKPFQEAEVLARVKVHLSIRELTQNLQREIEERKRVEAELAKANASLHRLAH
IDGLTQVANRYRFDQDMEQVWRRLQRDHEPLSLILCDVDYFKLFNDHYGHQVGDDCLRQVALAIQKAVHRPDDLVARYGG
EEFAIVLPSTHAQGAEQVALGILSKIAELNIPHEFSTVSPQITLSLGIATVIPKSEQSLDGLIELTDKALYRAKEEGRNT
YCHHDCSQSPPSLSCSPSPLSLH

Sequences:

>Translated_343_residues
MPDSPKPSNILIVDDVPTNLTILAQTLRDQGFTVWVATSGNAALKQLAHGLPDLILLDIQMPGMNGLETCAKLKADLRTQ
DIPVIFMSALSEQANKVEGLSLGAVDYITKPFQEAEVLARVKVHLSIRELTQNLQREIEERKRVEAELAKANASLHRLAH
IDGLTQVANRYRFDQDMEQVWRRLQRDHEPLSLILCDVDYFKLFNDHYGHQVGDDCLRQVALAIQKAVHRPDDLVARYGG
EEFAIVLPSTHAQGAEQVALGILSKIAELNIPHEFSTVSPQITLSLGIATVIPKSEQSLDGLIELTDKALYRAKEEGRNT
YCHHDCSQSPPSLSCSPSPLSLH
>Mature_342_residues
PDSPKPSNILIVDDVPTNLTILAQTLRDQGFTVWVATSGNAALKQLAHGLPDLILLDIQMPGMNGLETCAKLKADLRTQD
IPVIFMSALSEQANKVEGLSLGAVDYITKPFQEAEVLARVKVHLSIRELTQNLQREIEERKRVEAELAKANASLHRLAHI
DGLTQVANRYRFDQDMEQVWRRLQRDHEPLSLILCDVDYFKLFNDHYGHQVGDDCLRQVALAIQKAVHRPDDLVARYGGE
EFAIVLPSTHAQGAEQVALGILSKIAELNIPHEFSTVSPQITLSLGIATVIPKSEQSLDGLIELTDKALYRAKEEGRNTY
CHHDCSQSPPSLSCSPSPLSLH

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=36.6120218579235, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=32.9545454545455, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=34.5679012345679, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=33.1460674157303, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=36.1963190184049, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=40.3508771929825, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788394, Length=137, Percent_Identity=35.036496350365, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787541, Length=176, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=33.7423312883436, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787802, Length=187, Percent_Identity=34.2245989304813, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788381, Length=168, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790437, Length=104, Percent_Identity=41.3461538461538, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=34.1880341880342, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=35.042735042735, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790863, Length=138, Percent_Identity=35.5072463768116, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=36.7521367521368, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=36.4406779661017, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=34.4827586206897, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=191, Percent_Identity=28.2722513089005, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994928, Length=121, Percent_Identity=33.8842975206612, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=35.8974358974359, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367329, Length=118, Percent_Identity=41.5254237288136, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789149, Length=105, Percent_Identity=35.2380952380952, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 38056; Mature: 37925

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSPKPSNILIVDDVPTNLTILAQTLRDQGFTVWVATSGNAALKQLAHGLPDLILLDIQ
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEE
MPGMNGLETCAKLKADLRTQDIPVIFMSALSEQANKVEGLSLGAVDYITKPFQEAEVLAR
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHH
VKVHLSIRELTQNLQREIEERKRVEAELAKANASLHRLAHIDGLTQVANRYRFDQDMEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WRRLQRDHEPLSLILCDVDYFKLFNDHYGHQVGDDCLRQVALAIQKAVHRPDDLVARYGG
HHHHHCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
EEFAIVLPSTHAQGAEQVALGILSKIAELNIPHEFSTVSPQITLSLGIATVIPKSEQSLD
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHEECCCCHHHHH
GLIELTDKALYRAKEEGRNTYCHHDCSQSPPSLSCSPSPLSLH
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDSPKPSNILIVDDVPTNLTILAQTLRDQGFTVWVATSGNAALKQLAHGLPDLILLDIQ
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEE
MPGMNGLETCAKLKADLRTQDIPVIFMSALSEQANKVEGLSLGAVDYITKPFQEAEVLAR
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHH
VKVHLSIRELTQNLQREIEERKRVEAELAKANASLHRLAHIDGLTQVANRYRFDQDMEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WRRLQRDHEPLSLILCDVDYFKLFNDHYGHQVGDDCLRQVALAIQKAVHRPDDLVARYGG
HHHHHCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
EEFAIVLPSTHAQGAEQVALGILSKIAELNIPHEFSTVSPQITLSLGIATVIPKSEQSLD
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHEECCCCHHHHH
GLIELTDKALYRAKEEGRNTYCHHDCSQSPPSLSCSPSPLSLH
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]