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The map label for this gene is serC [H]

Identifier: 158318945

GI number: 158318945

Start: 8825235

End: 8826359

Strand: Reverse

Name: serC [H]

Synonym: Franean1_7228

Alternate gene names: 158318945

Gene position: 8826359-8825235 (Counterclockwise)

Preceding gene: 158318946

Following gene: 158318940

Centisome position: 98.27

GC content: 71.91

Gene sequence:

>1125_bases
ATGCCTGACACCCCGACGATCGTCCTGCCGGAGTCACTGCGCCCGGTCGACGGTCGGTTCGGCTGCGGGCCCTCCAAGGT
CCGCACCGAAGCCGTGCAGGCTCTCGCCGCGAGCGGGGCCTCCCTCCTCGGTACCTCGCACCGGCAGAAGCCGGTGAAGA
ACCTGGTCGGACGGGTCCGCGCCGGCCTGGCCGACCTGTTCTCCCTCCCCGAGGGCTACGAGGTGGTCCTCGGGATCGGC
GGCGCCACCGCGTTCTGGGACGCCGCCGCCTTCAACCTGGTGCGGGAGCGCTCCCAGCACCTGGTCTTCGGCGAGTTCGG
TGGCAAGTTCGCCGACACCACCAAGGGCGCCCCGTTCCTGGCCGCGCCGTCGGTGGTCAAGTCCGAGCCGGGTACCCACC
CGGACTGGGCTCCCGAGCCCGGCGTCGACGTCTACGCCACGCCGCACAACGAGACGTCCACCGGCGTGGCCCGGCCGGTG
CGCCGCCCCGTCGGCGCCGACGCGGGCGCGCTGCACCTGGTGGACGCCACCTCGGGCGCCGGCGGCCTGCCCGTCGACCT
CACCGAGGTGGACGTCTACTACTTCGCGCCGCAGAAGTGCTTCGCCTCCGACGGTGGGCTCTGGGCGGCCCTGATGTCGC
CGGCGGCGATCGCCCGGCTCGGCGAGATCGCGGCGACGGACCGCTGGATCCCGCCCTTCCTGGACCTGACGACCGCGCTG
GACAACAGCACGAAGGACCAGACCTACAACACCCCGGCCGTGTCCACGCTGTTCCTGTTCGCCGAGCAGCTCGACTGGAT
GCTGGGCAACGGCGGCCTGGACTGGTGTGTGCGCCGCACCGGAGAGTCCTCCTCGATCCTGTACAACTGGGCCGAGAAGA
CGCCGTACACGACGCCGTTCGTCACCGACCCGGCGCACCGCTCGCAGGTCGTCGTCACGATCGACTTCGAGGGCGTCGAC
GCCGCCGCGGTGGCCAAGGTGCTGCGCGCCAACGGCGTGGTCGACGTCGAGCCCTACCGCAAGCTGGGCCGCAACCAGCT
CCGGGTGGCCTGCTTCCCCGCGGTCGAGCCGTCGGACGTCGAGACCCTGACCAGCGCCATCGACCACGTGGTCGAGCGCC
TGTAG

Upstream 100 bases:

>100_bases
GGCTGGAGCGCTCACATCCTGGAGCAGCAGCGCACCAGCCGGCTCATCCGCCCGTCCGCCCGCTACGTCGGCCCCGCTCC
GCGGCCGCTGGGGGACGTCC

Downstream 100 bases:

>100_bases
CCGGGACGGCGCGGCCTCCCCGGGGCCGACGCGTTCGGCCGTGAGGTTGGCACCTGAGTGCTGATATCGGGCCGAGGAGA
CAACGTGTCTCCTCGGCCCG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MPDTPTIVLPESLRPVDGRFGCGPSKVRTEAVQALAASGASLLGTSHRQKPVKNLVGRVRAGLADLFSLPEGYEVVLGIG
GATAFWDAAAFNLVRERSQHLVFGEFGGKFADTTKGAPFLAAPSVVKSEPGTHPDWAPEPGVDVYATPHNETSTGVARPV
RRPVGADAGALHLVDATSGAGGLPVDLTEVDVYYFAPQKCFASDGGLWAALMSPAAIARLGEIAATDRWIPPFLDLTTAL
DNSTKDQTYNTPAVSTLFLFAEQLDWMLGNGGLDWCVRRTGESSSILYNWAEKTPYTTPFVTDPAHRSQVVVTIDFEGVD
AAAVAKVLRANGVVDVEPYRKLGRNQLRVACFPAVEPSDVETLTSAIDHVVERL

Sequences:

>Translated_374_residues
MPDTPTIVLPESLRPVDGRFGCGPSKVRTEAVQALAASGASLLGTSHRQKPVKNLVGRVRAGLADLFSLPEGYEVVLGIG
GATAFWDAAAFNLVRERSQHLVFGEFGGKFADTTKGAPFLAAPSVVKSEPGTHPDWAPEPGVDVYATPHNETSTGVARPV
RRPVGADAGALHLVDATSGAGGLPVDLTEVDVYYFAPQKCFASDGGLWAALMSPAAIARLGEIAATDRWIPPFLDLTTAL
DNSTKDQTYNTPAVSTLFLFAEQLDWMLGNGGLDWCVRRTGESSSILYNWAEKTPYTTPFVTDPAHRSQVVVTIDFEGVD
AAAVAKVLRANGVVDVEPYRKLGRNQLRVACFPAVEPSDVETLTSAIDHVVERL
>Mature_373_residues
PDTPTIVLPESLRPVDGRFGCGPSKVRTEAVQALAASGASLLGTSHRQKPVKNLVGRVRAGLADLFSLPEGYEVVLGIGG
ATAFWDAAAFNLVRERSQHLVFGEFGGKFADTTKGAPFLAAPSVVKSEPGTHPDWAPEPGVDVYATPHNETSTGVARPVR
RPVGADAGALHLVDATSGAGGLPVDLTEVDVYYFAPQKCFASDGGLWAALMSPAAIARLGEIAATDRWIPPFLDLTTALD
NSTKDQTYNTPAVSTLFLFAEQLDWMLGNGGLDWCVRRTGESSSILYNWAEKTPYTTPFVTDPAHRSQVVVTIDFEGVDA
AAVAKVLRANGVVDVEPYRKLGRNQLRVACFPAVEPSDVETLTSAIDHVVERL

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=379, Percent_Identity=23.7467018469657, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006272
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39855; Mature: 39724

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTPTIVLPESLRPVDGRFGCGPSKVRTEAVQALAASGASLLGTSHRQKPVKNLVGRVR
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
AGLADLFSLPEGYEVVLGIGGATAFWDAAAFNLVRERSQHLVFGEFGGKFADTTKGAPFL
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCE
AAPSVVKSEPGTHPDWAPEPGVDVYATPHNETSTGVARPVRRPVGADAGALHLVDATSGA
ECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCC
GGLPVDLTEVDVYYFAPQKCFASDGGLWAALMSPAAIARLGEIAATDRWIPPFLDLTTAL
CCCCEEEEEEEEEEECCHHHHCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHH
DNSTKDQTYNTPAVSTLFLFAEQLDWMLGNGGLDWCVRRTGESSSILYNWAEKTPYTTPF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCC
VTDPAHRSQVVVTIDFEGVDAAAVAKVLRANGVVDVEPYRKLGRNQLRVACFPAVEPSDV
EECCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEECHHHHHCCCCCEEEEEECCCCCCHH
ETLTSAIDHVVERL
HHHHHHHHHHHHHC
>Mature Secondary Structure 
PDTPTIVLPESLRPVDGRFGCGPSKVRTEAVQALAASGASLLGTSHRQKPVKNLVGRVR
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
AGLADLFSLPEGYEVVLGIGGATAFWDAAAFNLVRERSQHLVFGEFGGKFADTTKGAPFL
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCE
AAPSVVKSEPGTHPDWAPEPGVDVYATPHNETSTGVARPVRRPVGADAGALHLVDATSGA
ECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCC
GGLPVDLTEVDVYYFAPQKCFASDGGLWAALMSPAAIARLGEIAATDRWIPPFLDLTTAL
CCCCEEEEEEEEEEECCHHHHCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHH
DNSTKDQTYNTPAVSTLFLFAEQLDWMLGNGGLDWCVRRTGESSSILYNWAEKTPYTTPF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCC
VTDPAHRSQVVVTIDFEGVDAAAVAKVLRANGVVDVEPYRKLGRNQLRVACFPAVEPSDV
EECCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEECHHHHHCCCCCEEEEEECCCCCCHH
ETLTSAIDHVVERL
HHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]