Click here to switch to the map view.

The map label for this gene is gltA [H]

Identifier: 158318944

GI number: 158318944

Start: 8823435

End: 8824802

Strand: Direct

Name: gltA [H]

Synonym: Franean1_7227

Alternate gene names: 158318944

Gene position: 8823435-8824802 (Clockwise)

Preceding gene: 158318943

Following gene: 158318947

Centisome position: 98.23

GC content: 66.59

Gene sequence:

>1368_bases
GTGACCGAGCAGGTCAGTAGCCTGACTGTCACCGACAACCGCACCGGTCGGACGTACGAGGTACCGGTGGCTGACGGCAC
GATCCGCGCCAGTGCGTTCCGTGCCATCAAGGTCGATGACGACGACTTCGGTCTCATGGCGTACGACCCCGCCTTCACCA
ACACGGCCAGCTGCCGCAGCGCGATCACCTACATCGACGGTGACGCCGGCATCCTGCGCTACCGCGGTTACCCGATCCAG
GAGCTGGCTGAGAAGAGCAGCTTCCTCGAGGTCGCCTACCTGCTGCTGGCCGGCGAGCTCCCCACCTCGGACGAGCTCTC
CACCTGGGAAGACGAGATCACGCACCACACCCTGGTGCATGAGTCGATCAAGAAGTTCATCGACGGCTTCCACCACGACG
CCCACCCGATGGGCATGCTCGTGTCGACCGTCGGCGCGCTGTCGACCTTCTACCCGGACGCCAAGACGATCGACGACCCC
GGCCTGCGCCGGCTGCAGATCGTCCGGCTCATCGCGAAGATCACCACCCTGGCGGCGTTCTCCTACCGGCACTCGGTCGG
TTTCCCGTACGTCTACCCGGATAATGATCTTTCGTACGCCGGCAACTTCCTCAACATGATGTGGAAGGCCACCGAGCTCA
AGTACGAGCCGGACCCGAACCTCGAGCACGCCCTCGACGTGCTGTTCATCCTGCACGCCGACCACGAGCAGAACTGCTCC
GCCAACGCGATGCGGGCCGTCGGCAGCTCCCAGGCCGACCCGTTCTCCGCCGCGGCCGCGGCGATCGCCGCGCTCTACGG
CCCGCTGCACGGTGGTGCCAACGAGCAGGTCCTGCGGATGCTCGCCGACATCGGCTCGGTCGAGAACATCCCCGCCTTCA
TCGCTCAGGTGAAGGACGGCAAGAAGAAGCTCATGGGCTTCGGCCACCGGATCTACAAGAACTACGACCCGCGGGCCCGG
GTGATCCGCCAGGTCGCCGACGAGGTCTTCAAGGTCACCGGGACGAACCCGCTGCTCGACCTCGCGATGGAGCTCGAGCG
GATCGCCCTCGAGGACGAGTACTTCATCTCGCGCAAGCTCTACCCGAACGTGGACTTCTACACCGGCATCATCTACCAGG
CCATGGGCTTCCCGGTGGAGATGTTCCCGGTGCTGTTCGCGATCGGCCGGATGCCGGGCTGGCTGGCCCAGTGGGAGGAG
GGCCTGCTCGACCCCGAGCAGAAGATCGCCCGTCCGCGCCAGCTCTACATCGGCTACGACGAGCGCCCCTACGTCCCGAT
GCACGTCCGCTCCGCGGCCACGGACGCCGAGACCGACCCGATCGCCGCCCAGGCCGCGCAGGCCGCCCCCAGCCGCCCGC
TGCGCTGA

Upstream 100 bases:

>100_bases
CAACCGAACCAGTGAACCGGCGAGAGCGCTCCGAACCGGGCGCGCGCCCGAAGGTGGCCGACGCCGTCACCCGGCAGTGC
CATGGCGAGAGGAGCCCGGC

Downstream 100 bases:

>100_bases
CTTTTTCAGTCAGTCAGTCAGGGTGTTCCAAGGGCCAGGGCGCGACGGCCGTTGGCAGGGCCGTCGCGCAGGACTAGCTC
CCCACCGGCCCGCACACGTT

Product: citrate synthase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTEQVSSLTVTDNRTGRTYEVPVADGTIRASAFRAIKVDDDDFGLMAYDPAFTNTASCRSAITYIDGDAGILRYRGYPIQ
ELAEKSSFLEVAYLLLAGELPTSDELSTWEDEITHHTLVHESIKKFIDGFHHDAHPMGMLVSTVGALSTFYPDAKTIDDP
GLRRLQIVRLIAKITTLAAFSYRHSVGFPYVYPDNDLSYAGNFLNMMWKATELKYEPDPNLEHALDVLFILHADHEQNCS
ANAMRAVGSSQADPFSAAAAAIAALYGPLHGGANEQVLRMLADIGSVENIPAFIAQVKDGKKKLMGFGHRIYKNYDPRAR
VIRQVADEVFKVTGTNPLLDLAMELERIALEDEYFISRKLYPNVDFYTGIIYQAMGFPVEMFPVLFAIGRMPGWLAQWEE
GLLDPEQKIARPRQLYIGYDERPYVPMHVRSAATDAETDPIAAQAAQAAPSRPLR

Sequences:

>Translated_455_residues
MTEQVSSLTVTDNRTGRTYEVPVADGTIRASAFRAIKVDDDDFGLMAYDPAFTNTASCRSAITYIDGDAGILRYRGYPIQ
ELAEKSSFLEVAYLLLAGELPTSDELSTWEDEITHHTLVHESIKKFIDGFHHDAHPMGMLVSTVGALSTFYPDAKTIDDP
GLRRLQIVRLIAKITTLAAFSYRHSVGFPYVYPDNDLSYAGNFLNMMWKATELKYEPDPNLEHALDVLFILHADHEQNCS
ANAMRAVGSSQADPFSAAAAAIAALYGPLHGGANEQVLRMLADIGSVENIPAFIAQVKDGKKKLMGFGHRIYKNYDPRAR
VIRQVADEVFKVTGTNPLLDLAMELERIALEDEYFISRKLYPNVDFYTGIIYQAMGFPVEMFPVLFAIGRMPGWLAQWEE
GLLDPEQKIARPRQLYIGYDERPYVPMHVRSAATDAETDPIAAQAAQAAPSRPLR
>Mature_454_residues
TEQVSSLTVTDNRTGRTYEVPVADGTIRASAFRAIKVDDDDFGLMAYDPAFTNTASCRSAITYIDGDAGILRYRGYPIQE
LAEKSSFLEVAYLLLAGELPTSDELSTWEDEITHHTLVHESIKKFIDGFHHDAHPMGMLVSTVGALSTFYPDAKTIDDPG
LRRLQIVRLIAKITTLAAFSYRHSVGFPYVYPDNDLSYAGNFLNMMWKATELKYEPDPNLEHALDVLFILHADHEQNCSA
NAMRAVGSSQADPFSAAAAAIAALYGPLHGGANEQVLRMLADIGSVENIPAFIAQVKDGKKKLMGFGHRIYKNYDPRARV
IRQVADEVFKVTGTNPLLDLAMELERIALEDEYFISRKLYPNVDFYTGIIYQAMGFPVEMFPVLFAIGRMPGWLAQWEEG
LLDPEQKIARPRQLYIGYDERPYVPMHVRSAATDAETDPIAAQAAQAAPSRPLR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=385, Percent_Identity=29.0909090909091, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1786939, Length=384, Percent_Identity=53.3854166666667, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1786527, Length=381, Percent_Identity=31.2335958005249, Blast_Score=191, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17555174, Length=390, Percent_Identity=26.6666666666667, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319850, Length=331, Percent_Identity=25.9818731117825, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324328, Length=368, Percent_Identity=25.2717391304348, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325257, Length=398, Percent_Identity=24.3718592964824, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356863, Length=392, Percent_Identity=28.0612244897959, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24640126, Length=391, Percent_Identity=27.1099744245524, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24640124, Length=393, Percent_Identity=26.972010178117, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 50668; Mature: 50537

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQVSSLTVTDNRTGRTYEVPVADGTIRASAFRAIKVDDDDFGLMAYDPAFTNTASCRS
CCCCCCEEEEECCCCCCEEEEECCCCCEECCEEEEEEECCCCCCEEEECCCCCCCHHHHH
AITYIDGDAGILRYRGYPIQELAEKSSFLEVAYLLLAGELPTSDELSTWEDEITHHTLVH
EEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ESIKKFIDGFHHDAHPMGMLVSTVGALSTFYPDAKTIDDPGLRRLQIVRLIAKITTLAAF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SYRHSVGFPYVYPDNDLSYAGNFLNMMWKATELKYEPDPNLEHALDVLFILHADHEQNCS
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCCC
ANAMRAVGSSQADPFSAAAAAIAALYGPLHGGANEQVLRMLADIGSVENIPAFIAQVKDG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KKKLMGFGHRIYKNYDPRARVIRQVADEVFKVTGTNPLLDLAMELERIALEDEYFISRKL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCC
YPNVDFYTGIIYQAMGFPVEMFPVLFAIGRMPGWLAQWEEGLLDPEQKIARPRQLYIGYD
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCEEEECCC
ERPYVPMHVRSAATDAETDPIAAQAAQAAPSRPLR
CCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEQVSSLTVTDNRTGRTYEVPVADGTIRASAFRAIKVDDDDFGLMAYDPAFTNTASCRS
CCCCCEEEEECCCCCCEEEEECCCCCEECCEEEEEEECCCCCCEEEECCCCCCCHHHHH
AITYIDGDAGILRYRGYPIQELAEKSSFLEVAYLLLAGELPTSDELSTWEDEITHHTLVH
EEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ESIKKFIDGFHHDAHPMGMLVSTVGALSTFYPDAKTIDDPGLRRLQIVRLIAKITTLAAF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SYRHSVGFPYVYPDNDLSYAGNFLNMMWKATELKYEPDPNLEHALDVLFILHADHEQNCS
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCCC
ANAMRAVGSSQADPFSAAAAAIAALYGPLHGGANEQVLRMLADIGSVENIPAFIAQVKDG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KKKLMGFGHRIYKNYDPRARVIRQVADEVFKVTGTNPLLDLAMELERIALEDEYFISRKL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCC
YPNVDFYTGIIYQAMGFPVEMFPVLFAIGRMPGWLAQWEEGLLDPEQKIARPRQLYIGYD
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCEEEECCC
ERPYVPMHVRSAATDAETDPIAAQAAQAAPSRPLR
CCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]