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The map label for this gene is zwf [H]

Identifier: 158318796

GI number: 158318796

Start: 8625120

End: 8626598

Strand: Reverse

Name: zwf [H]

Synonym: Franean1_7068

Alternate gene names: 158318796

Gene position: 8626598-8625120 (Counterclockwise)

Preceding gene: 158318797

Following gene: 158318795

Centisome position: 96.04

GC content: 59.57

Gene sequence:

>1479_bases
ATGCCGCAGCTTATGTCGGTTGCCCCCTGCGAGATAGTAGTCTTCGGCGGCACAGGGGATCTGGCGATGCGCAAACTGAT
GCCAGCGCTGTACCACCGCGACCGAGACGGGCAACTCACCCCCGACTCGCGGGTCATTGCCGTGTCCCGGGCCGGACTCG
ATGATGCCGGATACCGCGACAAAGTTGATTCTGAACTGCGCCGGTTCGTCCCGGAGCTAATACACGAGCCGGATGTCCTA
GCTCGCTTTATCCAACGCCTGCACCACATCACGGTCGACGTGGCGGAGCACAGCACCTGGGATGAACTGCGGACACTTCT
GGCGGACGGAAAAGACCATGTGCGCGTCTTCTACCTTGCCTGTGCCCCACAACTGTTCGGGCCAACCTGTGTAGGCTTGC
AAACCAACGGATTAGTGACCGATAACTCCAGGGTGGTCCTCGAGAAGCCACTTGGGCATGATCTGGTCTCCGCGCGCCGG
ATTAACGATGAAGTCGGTGCGGTTTTTGCTGAGGAACAGATATTCCGTATCGACCACTACCTCGGTAAAGAAACCGTCCA
GAACCTCCTTGTGCTACGCTTCGCCAACTCCCTTCTTGAGCCGCTGTGGAATTCTGGTGCGATCGACCATGTACAGATTA
CGGTCGCAGAAACAATTGGCATCGGAGGGCGCGGCGACTATTACGATGGCTCGGGTGCCATACGTGACATGGTACAGAAT
CACCTTCTGCAACTGCTCTGTCTGGTGGCGATGGAACCACCCAGCCGACTTGACCGCGAGGCGGTCCGCGACGAGAAGCT
AAAGATTCTCCAGGCCCTATCCCCACTGACACTCGGTGACGTGGAACGGTGCGTCGTCCGAGGACAGTACACGGCCGGAC
TCGTAGAGGGAGCTCCAGTTCCTTCTTACCAGGACGAAGTTGATGGGAGCACGAGTACCACCGAGACGTTTGTGGCGCTG
AAGGTCGAGGTCCAGAACTGGCGCTGGTCCGGGGTACCCTTCTACCTGCGTACCGGCAAGAGGCTAGATCGTCATGCATC
GGAGATCGTGGTTCAGTTCCGACCGGTACCACATTCAATCTTCCCGGGTATCAAGGATGCGATTTCTCCTAACGCTCTTG
TGCTGCGGCTGCAACCTGACGAGGGCGTACGCCTCCACTTGATGGCCAAAGAACCGGGCCCGGGCGGCGTGCGACTGCGT
CCAGTCCACCTCAACCTCAGCTTCGCCGAGACTTTCAAGTCACGCCTGCCCGATGCCTACGAGCGGCTACTCATGGACGT
CGTTCGTGGCAACCCGACGTTGTTCATGCGACGCGACGAGGTCGAGGCCGCATGGGCGTGGGTGGAGCCCATCCTGGCCG
CTCTGGCGGCGTCAATTGACTCACCGAGGCGCTACGCAGCTGGCACTGGTGGACCTGCTGCAGCGATCGCATTGATCGAA
CGTGACGGCCGCACGTGGCATGAGGAGGTAGCAGAATGA

Upstream 100 bases:

>100_bases
AGTTGGAGCGGCGTCCGGTAAACGAGGTACTGAATTGCGGAACCTCACTGACGAACAGTGCGACAACCCGCACGGCAGGT
TCATTTCGATAGGAGAACCC

Downstream 100 bases:

>100_bases
GTGTGAACACGGTCCTGCACCCGGTTGTCGCTGAGGTGACTGAACGGGTCGCCGCTCGCAGTGCGGCAACTCGCGAAGCC
TATCTCTCCCGCGTCCAGGC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGYRDKVDSELRRFVPELIHEPDVL
ARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSARR
INDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAETIGIGGRGDYYDGSGAIRDMVQN
HLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGAPVPSYQDEVDGSTSTTETFVAL
KVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVRLR
PVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAASIDSPRRYAAGTGGPAAAIALIE
RDGRTWHEEVAE

Sequences:

>Translated_492_residues
MPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGYRDKVDSELRRFVPELIHEPDVL
ARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSARR
INDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAETIGIGGRGDYYDGSGAIRDMVQN
HLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGAPVPSYQDEVDGSTSTTETFVAL
KVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVRLR
PVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAASIDSPRRYAAGTGGPAAAIALIE
RDGRTWHEEVAE
>Mature_491_residues
PQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGYRDKVDSELRRFVPELIHEPDVLA
RFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSARRI
NDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAETIGIGGRGDYYDGSGAIRDMVQNH
LLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGAPVPSYQDEVDGSTSTTETFVALK
VEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVRLRP
VHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAASIDSPRRYAAGTGGPAAAIALIER
DGRTWHEEVAE

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=480, Percent_Identity=37.0833333333333, Blast_Score=300, Evalue=3e-81,
Organism=Homo sapiens, GI109389365, Length=480, Percent_Identity=37.0833333333333, Blast_Score=300, Evalue=3e-81,
Organism=Homo sapiens, GI52145310, Length=506, Percent_Identity=30.8300395256917, Blast_Score=172, Evalue=7e-43,
Organism=Escherichia coli, GI1788158, Length=493, Percent_Identity=48.2758620689655, Blast_Score=468, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17538218, Length=488, Percent_Identity=37.7049180327869, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6324088, Length=485, Percent_Identity=36.0824742268041, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24643352, Length=478, Percent_Identity=35.9832635983264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24643350, Length=478, Percent_Identity=35.9832635983264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI221513548, Length=497, Percent_Identity=29.9798792756539, Blast_Score=201, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 54635; Mature: 54504

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGYRD
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCH
KVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHCCCCCEEEEEEE
CAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSARRINDEVGAVFAEEQIFRIDHY
ECHHHCCCEEECEECCCEEECCCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
LGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAETIGIGGRGDYYDGSGAIRDMVQN
HCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHEECCCCCCCCCCCCHHHHHHHHH
HLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGAPV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCCCCCC
PSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSI
CCCHHHCCCCCCCCEEEEEEEEEEECEEECCCCEEEECCCHHHHHHHHEEEEEECCCHHH
FPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVRLRPVHLNLSFAETFKSRLPDAY
CCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEEEEECHHHHHHHHHCCHHH
ERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAASIDSPRRYAAGTGGPAAAIALIE
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHEEEEEE
RDGRTWHEEVAE
CCCCHHHHHHCC
>Mature Secondary Structure 
PQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGYRD
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCH
KVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHCCCCCEEEEEEE
CAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSARRINDEVGAVFAEEQIFRIDHY
ECHHHCCCEEECEECCCEEECCCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
LGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAETIGIGGRGDYYDGSGAIRDMVQN
HCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHEECCCCCCCCCCCCHHHHHHHHH
HLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGAPV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCCCCCC
PSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSI
CCCHHHCCCCCCCCEEEEEEEEEEECEEECCCCEEEECCCHHHHHHHHEEEEEECCCHHH
FPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVRLRPVHLNLSFAETFKSRLPDAY
CCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEEEEECHHHHHHHHHCCHHH
ERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAASIDSPRRYAAGTGGPAAAIALIE
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHEEEEEE
RDGRTWHEEVAE
CCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA