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The map label for this gene is edd [H]

Identifier: 158318795

GI number: 158318795

Start: 8623291

End: 8625123

Strand: Reverse

Name: edd [H]

Synonym: Franean1_7067

Alternate gene names: 158318795

Gene position: 8625123-8623291 (Counterclockwise)

Preceding gene: 158318796

Following gene: 158318794

Centisome position: 96.03

GC content: 63.56

Gene sequence:

>1833_bases
ATGAGTGTGAACACGGTCCTGCACCCGGTTGTCGCTGAGGTGACTGAACGGGTCGCCGCTCGCAGTGCGGCAACTCGCGA
AGCCTATCTCTCCCGCGTCCAGGCAGCAGCCCAGGCGGGCCCGACCCGGGGCAGTCTAGGGTGCGCTAATCTTGCGCACG
GCTTCGCTGCATGCGCTCCGGCAGACAAGATCGAACTCCGCGGAGCGGCCAAGCCCGACATTGCAATCGTGTCAGCATAC
AACGATATGCTCTCCGCCCATCAGCCTTTTGAGACCTATCCCGCGGTTCTCAAGCGTGCGGTGAGCGAGGCTGGTGGTGT
CGCGCAGTTTGCCGGCGGTGTGCCCGCAATGTGCGATGGCATTACCCAGGGCCGTGCGGGTATGGAATTGTCCTTGTTCA
GTCGTGATGTGATTGCGATGGCCACGGCGGTGGCGCTGGCGCACGACATGTTCGACGGCGTGCTACTACTCGGGGTGTGC
GACAAGATCGTCCCCGGGCTCGTTATCGGTGCGCTGTCCTTCGGTCACCTACCGGCCATCCTTGTCCCTGCCGGGCCGAT
GACCTCCGGGTTACCCAATGCAGCCAAGAGCCTCACCCGCCAGTTGTACGCCGAAGGCAAGGCCAGTCGACAGGAGCTCC
TCGATGCGGAGGCAGCCGCCTATCACAGCGCGGGAACGTGTACGTTCTACGGCACGGCCAATACCAATCAGCTGCTCATG
GAGATCATGGGCCTGCACCTTCCAGGTGCCAGCTTCGTCAACCCGGATACTGCTCTGCGTAACGCCCTCACCGCCGCTGC
CGGGCATCGGATTACCCAGCTGACCACTCTCGGCGATTCCCACACGCCAATCGGCGAGATTATTGATGAGCGCGCGATTG
TAAACGGCGTTGTTGGCTTGCTTGCCAGCGGCGGTTCGACGAACCACACCATGCATCTGGTCGCGATTGCCGCTGCCGCA
GGAATACGGTTGACCTGGGACGATTTCGGCGCCCTGTCGGCTGCGGTGCCATTGCTTGCACGGATCTACCCCAATGGCCC
TGCCGACGTGAACCATTTCCACGCAGCCGGAGGCACAGCGTTCCTCATCAGCGAACTGCTGGACGCAGGCATGCTGCACG
GTGACGTCCGTACCGTCGCGGGCGACGGCCTCGATCACTACCGGCAGGAACCGGTCCTGGTAGGTGACGAGCTCCTCTGG
AGAAGCGGGGCGACAAAAAGCCTCGATGGGGACGTGCTGCGCCAGGTTTCCCACCCATTCGCGCCCGACGGCGGTTTGCG
TATGCTCAGCGGCAGCCTCGGTCGGGCGGTAGTGAAGACGTCTGCGGTGCGAGCCGAACATCTCCTCACCCAGGCACCAG
CGAGGGTTTTCGACGACCAGGCAGAATTCCTTGCCGCATTCGAGGCGGGCGAGCTTAGCGGTGATCTCGTAGCAGTCATC
CGTTACCAGGGCCCACGCGCCAACGGCATGCCTGAGCTTCACAAACTCATCCCGGCCCTCGGCGTACTGCAGGACCGCGG
CCACAGGGTTGCCCTCGTGACAGACGGAAGGATGTCCGGCGCTTCGGGAAAAATTCCTGCCGCGATCCATGTCACTCCGG
AGGCAGCTGCGGGCGGGCCAATCGCCCGTGTACGAGACGGCGACGTCATCCGGCTGGACGCTACGACTGGTTCGCTCGAG
GTGATCGGCACTGATCTCAGTGATCGTGAGCCCACGGAGAAGTCACTTGCCTCGGACACGGGGATAGGGACCGGACGCGA
GCTCTTCGCTGCGTTCCGGAGCGTTGTCGGCCCAGCCGACTCCGGGGCCAGCGTGCTGACGGTAACGGCATGA

Upstream 100 bases:

>100_bases
TTGACTCACCGAGGCGCTACGCAGCTGGCACTGGTGGACCTGCTGCAGCGATCGCATTGATCGAACGTGACGGCCGCACG
TGGCATGAGGAGGTAGCAGA

Downstream 100 bases:

>100_bases
CCTCGATCTCACGCCCTTCGTCCCTGCTCAACATCGCGCCAGTGATACCCGTCGTCGTCGTGCATGACATCCGAACAGCG
GTGCCGCTCGCCCGTGCTCT

Product: phosphogluconate dehydratase

Products: NA

Alternate protein names: 6-phosphogluconate dehydratase [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSVNTVLHPVVAEVTERVAARSAATREAYLSRVQAAAQAGPTRGSLGCANLAHGFAACAPADKIELRGAAKPDIAIVSAY
NDMLSAHQPFETYPAVLKRAVSEAGGVAQFAGGVPAMCDGITQGRAGMELSLFSRDVIAMATAVALAHDMFDGVLLLGVC
DKIVPGLVIGALSFGHLPAILVPAGPMTSGLPNAAKSLTRQLYAEGKASRQELLDAEAAAYHSAGTCTFYGTANTNQLLM
EIMGLHLPGASFVNPDTALRNALTAAAGHRITQLTTLGDSHTPIGEIIDERAIVNGVVGLLASGGSTNHTMHLVAIAAAA
GIRLTWDDFGALSAAVPLLARIYPNGPADVNHFHAAGGTAFLISELLDAGMLHGDVRTVAGDGLDHYRQEPVLVGDELLW
RSGATKSLDGDVLRQVSHPFAPDGGLRMLSGSLGRAVVKTSAVRAEHLLTQAPARVFDDQAEFLAAFEAGELSGDLVAVI
RYQGPRANGMPELHKLIPALGVLQDRGHRVALVTDGRMSGASGKIPAAIHVTPEAAAGGPIARVRDGDVIRLDATTGSLE
VIGTDLSDREPTEKSLASDTGIGTGRELFAAFRSVVGPADSGASVLTVTA

Sequences:

>Translated_610_residues
MSVNTVLHPVVAEVTERVAARSAATREAYLSRVQAAAQAGPTRGSLGCANLAHGFAACAPADKIELRGAAKPDIAIVSAY
NDMLSAHQPFETYPAVLKRAVSEAGGVAQFAGGVPAMCDGITQGRAGMELSLFSRDVIAMATAVALAHDMFDGVLLLGVC
DKIVPGLVIGALSFGHLPAILVPAGPMTSGLPNAAKSLTRQLYAEGKASRQELLDAEAAAYHSAGTCTFYGTANTNQLLM
EIMGLHLPGASFVNPDTALRNALTAAAGHRITQLTTLGDSHTPIGEIIDERAIVNGVVGLLASGGSTNHTMHLVAIAAAA
GIRLTWDDFGALSAAVPLLARIYPNGPADVNHFHAAGGTAFLISELLDAGMLHGDVRTVAGDGLDHYRQEPVLVGDELLW
RSGATKSLDGDVLRQVSHPFAPDGGLRMLSGSLGRAVVKTSAVRAEHLLTQAPARVFDDQAEFLAAFEAGELSGDLVAVI
RYQGPRANGMPELHKLIPALGVLQDRGHRVALVTDGRMSGASGKIPAAIHVTPEAAAGGPIARVRDGDVIRLDATTGSLE
VIGTDLSDREPTEKSLASDTGIGTGRELFAAFRSVVGPADSGASVLTVTA
>Mature_609_residues
SVNTVLHPVVAEVTERVAARSAATREAYLSRVQAAAQAGPTRGSLGCANLAHGFAACAPADKIELRGAAKPDIAIVSAYN
DMLSAHQPFETYPAVLKRAVSEAGGVAQFAGGVPAMCDGITQGRAGMELSLFSRDVIAMATAVALAHDMFDGVLLLGVCD
KIVPGLVIGALSFGHLPAILVPAGPMTSGLPNAAKSLTRQLYAEGKASRQELLDAEAAAYHSAGTCTFYGTANTNQLLME
IMGLHLPGASFVNPDTALRNALTAAAGHRITQLTTLGDSHTPIGEIIDERAIVNGVVGLLASGGSTNHTMHLVAIAAAAG
IRLTWDDFGALSAAVPLLARIYPNGPADVNHFHAAGGTAFLISELLDAGMLHGDVRTVAGDGLDHYRQEPVLVGDELLWR
SGATKSLDGDVLRQVSHPFAPDGGLRMLSGSLGRAVVKTSAVRAEHLLTQAPARVFDDQAEFLAAFEAGELSGDLVAVIR
YQGPRANGMPELHKLIPALGVLQDRGHRVALVTDGRMSGASGKIPAAIHVTPEAAAGGPIARVRDGDVIRLDATTGSLEV
IGTDLSDREPTEKSLASDTGIGTGRELFAAFRSVVGPADSGASVLTVTA

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI1788157, Length=603, Percent_Identity=59.7014925373134, Blast_Score=748, Evalue=0.0,
Organism=Escherichia coli, GI48994964, Length=581, Percent_Identity=30.2925989672978, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1786464, Length=513, Percent_Identity=30.2144249512671, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI2367371, Length=498, Percent_Identity=29.3172690763052, Blast_Score=142, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6322476, Length=491, Percent_Identity=32.1792260692464, Blast_Score=209, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004786
- InterPro:   IPR015928
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.12 [H]

Molecular weight: Translated: 62912; Mature: 62781

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00886 ILVD_EDD_1 ; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNTVLHPVVAEVTERVAARSAATREAYLSRVQAAAQAGPTRGSLGCANLAHGFAACAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
ADKIELRGAAKPDIAIVSAYNDMLSAHQPFETYPAVLKRAVSEAGGVAQFAGGVPAMCDG
CCCEEECCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHC
ITQGRAGMELSLFSRDVIAMATAVALAHDMFDGVLLLGVCDKIVPGLVIGALSFGHLPAI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVPAGPMTSGLPNAAKSLTRQLYAEGKASRQELLDAEAAAYHSAGTCTFYGTANTNQLLM
EECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EIMGLHLPGASFVNPDTALRNALTAAAGHRITQLTTLGDSHTPIGEIIDERAIVNGVVGL
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LASGGSTNHTMHLVAIAAAAGIRLTWDDFGALSAAVPLLARIYPNGPADVNHFHAAGGTA
HHCCCCCCCCEEHEEEHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHH
FLISELLDAGMLHGDVRTVAGDGLDHYRQEPVLVGDELLWRSGATKSLDGDVLRQVSHPF
HHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCEEECCHHHHCCCCCCCCCHHHHHHHCCCC
APDGGLRMLSGSLGRAVVKTSAVRAEHLLTQAPARVFDDQAEFLAAFEAGELSGDLVAVI
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RYQGPRANGMPELHKLIPALGVLQDRGHRVALVTDGRMSGASGKIPAAIHVTPEAAAGGP
EECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
IARVRDGDVIRLDATTGSLEVIGTDLSDREPTEKSLASDTGIGTGRELFAAFRSVVGPAD
EEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCC
SGASVLTVTA
CCCCEEEEEC
>Mature Secondary Structure 
SVNTVLHPVVAEVTERVAARSAATREAYLSRVQAAAQAGPTRGSLGCANLAHGFAACAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
ADKIELRGAAKPDIAIVSAYNDMLSAHQPFETYPAVLKRAVSEAGGVAQFAGGVPAMCDG
CCCEEECCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHC
ITQGRAGMELSLFSRDVIAMATAVALAHDMFDGVLLLGVCDKIVPGLVIGALSFGHLPAI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVPAGPMTSGLPNAAKSLTRQLYAEGKASRQELLDAEAAAYHSAGTCTFYGTANTNQLLM
EECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EIMGLHLPGASFVNPDTALRNALTAAAGHRITQLTTLGDSHTPIGEIIDERAIVNGVVGL
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LASGGSTNHTMHLVAIAAAAGIRLTWDDFGALSAAVPLLARIYPNGPADVNHFHAAGGTA
HHCCCCCCCCEEHEEEHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHH
FLISELLDAGMLHGDVRTVAGDGLDHYRQEPVLVGDELLWRSGATKSLDGDVLRQVSHPF
HHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCEEECCHHHHCCCCCCCCCHHHHHHHCCCC
APDGGLRMLSGSLGRAVVKTSAVRAEHLLTQAPARVFDDQAEFLAAFEAGELSGDLVAVI
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RYQGPRANGMPELHKLIPALGVLQDRGHRVALVTDGRMSGASGKIPAAIHVTPEAAAGGP
EECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
IARVRDGDVIRLDATTGSLEVIGTDLSDREPTEKSLASDTGIGTGRELFAAFRSVVGPAD
EEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCC
SGASVLTVTA
CCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]