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The map label for this gene is eda [H]

Identifier: 158318794

GI number: 158318794

Start: 8622638

End: 8623294

Strand: Reverse

Name: eda [H]

Synonym: Franean1_7066

Alternate gene names: 158318794

Gene position: 8623294-8622638 (Counterclockwise)

Preceding gene: 158318795

Following gene: 158318793

Centisome position: 96.01

GC content: 62.86

Gene sequence:

>657_bases
ATGACCTCGATCTCACGCCCTTCGTCCCTGCTCAACATCGCGCCAGTGATACCCGTCGTCGTCGTGCATGACATCCGAAC
AGCGGTGCCGCTCGCCCGTGCTCTCGTCGCTGGAGGCCTGCATATCCTGGAGGTGACACTACGCACCGACGCAGCCCTAC
AGGCGATCGAGTTGATCACGGCGGAAGTGCCGGACATTCTCGTTGGCGCTGGAACGATCACCTCAAGCGATCAGGCAAGG
CAGTCCGTGGACGCCGGCGCACACTTCCTGGTCAGCCCCGGATGCACCGACCGGCTGCTAGACGCGATGGACGACAGCGG
CCTGCCTTATCTACCCGGTGTCGCTACCGTCTCGGAGATGCTTAAGGTTCTCGACCGCAGGAAGGTCGAGATGAAGTTCT
TCCCCGCCGGGGCTGCAGGAGGCATCCCCTACCTCCAAGCGGTAGCGGGACCGCTACCACAAATCCGATTCTGCCCGACT
GGCGGCATCACCGCTGCTACGGTTGGGGCCTATCTGGGCGAGCCAAATGTCGGATGCGTCGGCGGATCTTGGGTGACACC
ACCCGATGCCATCTGGGAAGGCGATTGGAAACAGATCACGCAACTTGCCCGCGGCGTGGCATCATGGCCGAACCGAGACG
GCATGGGCCATCGGTGA

Upstream 100 bases:

>100_bases
CCTCGGACACGGGGATAGGGACCGGACGCGAGCTCTTCGCTGCGTTCCGGAGCGTTGTCGGCCCAGCCGACTCCGGGGCC
AGCGTGCTGACGGTAACGGC

Downstream 100 bases:

>100_bases
ACCGCCCCAGCCTAGATGGGACGTGAACTGTCTGCGTCCGCGCGAACCGTCTGCGGCCGCCGCCACGGGGTCTACACTCA
GGCTGACAGACACAGAAAGT

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTSISRPSSLLNIAPVIPVVVVHDIRTAVPLARALVAGGLHILEVTLRTDAALQAIELITAEVPDILVGAGTITSSDQAR
QSVDAGAHFLVSPGCTDRLLDAMDDSGLPYLPGVATVSEMLKVLDRRKVEMKFFPAGAAGGIPYLQAVAGPLPQIRFCPT
GGITAATVGAYLGEPNVGCVGGSWVTPPDAIWEGDWKQITQLARGVASWPNRDGMGHR

Sequences:

>Translated_218_residues
MTSISRPSSLLNIAPVIPVVVVHDIRTAVPLARALVAGGLHILEVTLRTDAALQAIELITAEVPDILVGAGTITSSDQAR
QSVDAGAHFLVSPGCTDRLLDAMDDSGLPYLPGVATVSEMLKVLDRRKVEMKFFPAGAAGGIPYLQAVAGPLPQIRFCPT
GGITAATVGAYLGEPNVGCVGGSWVTPPDAIWEGDWKQITQLARGVASWPNRDGMGHR
>Mature_217_residues
TSISRPSSLLNIAPVIPVVVVHDIRTAVPLARALVAGGLHILEVTLRTDAALQAIELITAEVPDILVGAGTITSSDQARQ
SVDAGAHFLVSPGCTDRLLDAMDDSGLPYLPGVATVSEMLKVLDRRKVEMKFFPAGAAGGIPYLQAVAGPLPQIRFCPTG
GITAATVGAYLGEPNVGCVGGSWVTPPDAIWEGDWKQITQLARGVASWPNRDGMGHR

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=180, Percent_Identity=51.1111111111111, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 22795; Mature: 22663

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSISRPSSLLNIAPVIPVVVVHDIRTAVPLARALVAGGLHILEVTLRTDAALQAIELIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHH
AEVPDILVGAGTITSSDQARQSVDAGAHFLVSPGCTDRLLDAMDDSGLPYLPGVATVSEM
HHCCHHEEECCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LKVLDRRKVEMKFFPAGAAGGIPYLQAVAGPLPQIRFCPTGGITAATVGAYLGEPNVGCV
HHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCEE
GGSWVTPPDAIWEGDWKQITQLARGVASWPNRDGMGHR
CCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSISRPSSLLNIAPVIPVVVVHDIRTAVPLARALVAGGLHILEVTLRTDAALQAIELIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHH
AEVPDILVGAGTITSSDQARQSVDAGAHFLVSPGCTDRLLDAMDDSGLPYLPGVATVSEM
HHCCHHEEECCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHH
LKVLDRRKVEMKFFPAGAAGGIPYLQAVAGPLPQIRFCPTGGITAATVGAYLGEPNVGCV
HHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCEE
GGSWVTPPDAIWEGDWKQITQLARGVASWPNRDGMGHR
CCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8145647 [H]