Click here to switch to the map view.

The map label for this gene is yegE [H]

Identifier: 158318760

GI number: 158318760

Start: 8575299

End: 8579282

Strand: Reverse

Name: yegE [H]

Synonym: Franean1_7031

Alternate gene names: 158318760

Gene position: 8579282-8575299 (Counterclockwise)

Preceding gene: 158318761

Following gene: 158318755

Centisome position: 95.52

GC content: 68.42

Gene sequence:

>3984_bases
ATGACCATGGCCACTCGGATCTTTCCGGTCCGGCGCGGATCTGAAGATCGCAGGCCAAAGGATCGTAGATTTGGCGATCC
TCCTATATCGGGCGCGCTCGGCGCATCCGACCTGCGTGATCTCACCCGGCGCGGCCGGCTTCGGCGAGCCATGCCGCTGC
TGGTCGGCCTGGCAGCCTTTCTTCTTCTCGTCGCGGTCATCTTCGCCATCAGCAGTGAAAGCCTGGCGACCTCCGAGCGG
GAGCGGCTGAGTAACCGGGCACATCTGACCGAACAGATGGCGGCCTACACGTCGCGTGCCGTCGACCCTCAGCTTCAGCA
GTCCCGCGTCGACGCGGCCGGATTCTCCCTGACGGATCAAGCGCGCAACGCGCACTTGTTGACATCGTTTCGGATCAATC
CTGCAAGTGACCCTAACTTCGTCGTCGCTCTGTTGGACCGCGACGGGCATCCGCTGGTGTCCCGACCGGTGAGTGCCACG
ATTCCAGTGAGCGCCCTCGGTGACGCCTGGCCGACTGCGCTTGCCGGGCAGGCCGCGAGGTCGCCGGTGTTCGTCATCGA
TGGTCTTGTCGGCCGGGCGACAGTGGTGCCGGTCGGCGAAGGACGTCCGTGGGCCGCCCTTGTTACCGTCGCTACGGACG
ATCTGGCTCAACGCTTCGACGAGCAGCTCGGTTCGCTCGAGCTCGGTCCCGGGGGCCTCACCACTGTTGACTCGGCCGGG
GTCGCGGCATCCTCCTGGGATCCGGCGCTGGTCGGCCGGCGCGTCATCGACCCGGAAATGCTGCGCGGGATTCCGCCGCT
GCCGGCGCGGGTGTGGACGTCCGGGCATGGCTCCGACGAGGTGACGAACATCGCCGCCCAGCAGGCGAGCAGCGGATACA
TCAACCTGTTTCAGCAGCGAACCGACGCGTTCTACTCCGACCTGCGTGCACAGCAGTGGTCCCGGAACCTGACCGTGATC
GCCGTGGGAGCGGTGGCGATGCTGGGGCTGGTCGTCTTCGGCCTGCGCCGGGAGGTGAGCGCCCGCCGTGCTGGTAAGCG
GCTCGACGAGCTGTTGCGCAACACCCGGGACCTGATCGCCGTCGTCCGTCTGGACGGTGTGGTGAGCTTCCTGAGCCCGT
CGATCGAAAGGCTGCTCGGCAGCCGTGCCTCGGACTGGCTCGGTCGACCGCTGGCACAGCTCGTCCATCCGGCCGACCGG
GAGCGCCTCGACCGATTGCTGACCGATGGCGGCGCGGTCCTCGACGTCCGACTGTGTGGCGCCGACGGCGCCATCCACTG
GTTCGACCTGGAGGCCGCCGACCTTCCTCCGCGGGCCGGCCTGGCCGGTGTGCTGGTCACCTGCCATGAGATCGGGGAAC
GCAAGAAGCTGCAGGACCGGCTTGGTCATCAGGCACGCCACGACTTGCTGACCGGTCTGGCCAACCGGTCCGGGTTCGGT
GATCGGCTTGCCAGCGCGCTCGCCGTGAGCAGCGAGTCGAGCTGCGCCGTCCTTTATCTGGACCTTGACGGGTTCAAGCC
CATCAACGACTCGCTCGGACACGCGGCCGGAGACCGGGTGCTGGCGATCATCGGCGCGCGGTTGGCGGCGCTGTTGCGTG
AAGGCGACCTTGCCAGCCGGCTCGGCGGTGACGAGTTCGCGATGCTGCTTCGCGACAGCGACCTCGCGACTGCGAGTCTG
GTGGCGGATCGGGTGATCAGAGCCGTCGCCGAAAAGATCATTCTTGAGGGCGAGTGCGTGCAGGTAGGCGCGAGCGTGGG
CATCGCGATGGGCAGACCAGGCCGCAGCCGTGCTGACGAACTGATCCACGCCGCGGACACGGCGATGTACGCCGCCAAGC
GCGATGGCGGGAGTCGGGCCGCCATCGCGCTGCCCACCCCGTCCACAGCCGCCGACGCGGACGATATTCTTGGCCCGCGC
GACCTTGGCAGGCCCTCGGCCACCATTGCCGCCGTCGACGTAACAAACGTCGCGGACGATCACCCGGGTGCGCCGCAGCT
GGCAAACCCAGCAAGCGCGACCTCGGCAAGCCCGGCGAAACTGGTGGAACCGGCGGGATCGGCGGACCTGGAGCCGGGAA
GACCGCTCGGTTCGGCGGTACGAAAACCACCGTCCGCGCGCCCATGGTGGTGGTCCCGTCGCTCCGAGGCCGTCCGCTCC
ACACACCGTGGCGAGGCCGCAGCCCCTCAACGGCGCGCCCCCCAGATATGTTTCGGCCGTATCGTGCCGCTGTTGGTCGC
CGCGCTGACCTTGCTCGGTATCGCGTCGTTTGGTCTGTGGCAGGAGTCCCAGGCGCTACGGGCAGCGGAAGCAAGCGCGA
TGCGCGAACGCCTCGCGCAGACCGCACGCATGGCCGACTACATGTCGGCCATGCAGGACCCGCAGCCATTGGTCTCGGCC
GCGTCCGCCGAGTCATGGTCGCCGACGGATCTGACACACAACCAGACCATCCTGCAACGGTTCGCCCAGTCGCCCGAGGG
CGGACCGGACACCCTGGCCTCGCTGGTCGGCCTCGACGGACGAACGATCGCGGCCGAGCCGGCCGCTGCCCCGCCGATGC
CGATCGCTACGGACAGCCCGCAGTGGCAGGCGGTGCTGGCCGGGCGGGCGACCACCTCCCAGGTGGTCATGGTGGATGGA
GTCGCGCGGCTGTACACCCTGGCGCCGGTACTCGAGGACGGGCGCCCGGTCGCCGTCCTCACCCTCGGCCGCTCGGCGCG
AGACGCCCTGCCCAGCTTCTTCCTCGCCGCGCTCGGCGGTATGGGGCTGCGCGACGGCGGCGGCGCCGTCGTCGACCGCT
CCGGCCGGGCATCCTTCTCCTGGAACCCCGGCCTGGCCGGCCGGCCGCTGGTGAACCCGGCCGACCTGGCGGACCTGCGG
ATGGGGAAGGCCGAGCGGGTAACCCTCGTCGATGACTCGAACGAGATTATGCTCGCCGCGCCGATCTGGTCCCTTGACGG
TGCGTACTTCGTCTTCCAGCAACCCGCCACGGCCCTGTTCGCCGGGCTTCGGGAGGGCCAGGGCCTGCTTGCGGTAAGCC
TGTTCGGCACCATCGGCATCGCTATCCTCGGCATCGCCGTCTCGAATGCCCGCCGGGAGAACGCGCTGCGCCGCGAGGAA
TCCCAGCTGCACGCGCTGCTACACAATGCCCACGACATCGTCATCGTTGCCGATCGTGACTGTCGGATAACTTTTGCCAG
CTCCGACGCGACGGGTCTACTCGGCCAGCCCACGGCGGGCTGGATCGGAAAAATCTTCCCTGACCTCAGCCATCCCGAGG
ACGCCAGCCGCCTCCGGCAGTTCCTCGGTGCCCGCGACCGCGAAGGGCAGGGCGCGATCCGCGAGATCCGGCTACGCGCC
TGCGATGGCTATCGGTGGTTCGATATCCACGCCTCGGAGCCGCACCACACACCGGTCCTGTCCGGCATCGTCCTGACTTG
TCATGAGATCGGGGGACGCCGACAGATGCAGGCCGAACTCGCCTATCGGGCCAGCCACGACCCTCTCACAGGCCTGCCCA
ATCGGGCCGCGTTCGACCGCCATCTGGCGGCTGTGGCCGAACACGAGCAGGCCGGAACGAGCTTCGCCGTGCTTTTCATC
GACCTGGACAACTTCAAGCCCGTCAACGACAGGTTCGGCCACGCTGTCGGCGACGACGTCCTGCGCGTCATTGGCGCCCG
CATCGGGGCCGCATCCCGGAAGACGGACATGGTCAGCCGCCTCGGCGGAGATGAGTTCGCGGTCCTCGTCGACGAGGCCG
ACGACGATCTCGTCTGCGCCATCTCCGCGCGCATCCTCGAAACCAGCAGGCAGCCCATCGCGCTGGCCGGGACCACCATC
GCCCTCGGCGCCACTATCGGGATCGCGCTGTGCCGCGCCGGCATCGACGACCCCGAAACCGCCCTGCGCAATGCCGATAA
TGCTATGTATCGGGCCAAACGGGCGGGTCGTGACCGCTACGCCCTCTTCACCGACCGGCCCTGA

Upstream 100 bases:

>100_bases
CGGAGGGACCTCTGACTGGGAGGATTGTTTGTTTTGTCCGTAATCGCGCAGGACGGTTATTCGACCCGCCCAGCGTCCCG
GATGCGTCAGGCGGGCGGCG

Downstream 100 bases:

>100_bases
ACGTCCTGGTTCCCATGTGACCGCTACCGGCACAGCAGTCCAGCGCCGCCGATACTCGCCGCAGGCGACGACGACCGCCG
AGCCACCCACGACAACCCAC

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 1327; Mature: 1326

Protein sequence:

>1327_residues
MTMATRIFPVRRGSEDRRPKDRRFGDPPISGALGASDLRDLTRRGRLRRAMPLLVGLAAFLLLVAVIFAISSESLATSER
ERLSNRAHLTEQMAAYTSRAVDPQLQQSRVDAAGFSLTDQARNAHLLTSFRINPASDPNFVVALLDRDGHPLVSRPVSAT
IPVSALGDAWPTALAGQAARSPVFVIDGLVGRATVVPVGEGRPWAALVTVATDDLAQRFDEQLGSLELGPGGLTTVDSAG
VAASSWDPALVGRRVIDPEMLRGIPPLPARVWTSGHGSDEVTNIAAQQASSGYINLFQQRTDAFYSDLRAQQWSRNLTVI
AVGAVAMLGLVVFGLRREVSARRAGKRLDELLRNTRDLIAVVRLDGVVSFLSPSIERLLGSRASDWLGRPLAQLVHPADR
ERLDRLLTDGGAVLDVRLCGADGAIHWFDLEAADLPPRAGLAGVLVTCHEIGERKKLQDRLGHQARHDLLTGLANRSGFG
DRLASALAVSSESSCAVLYLDLDGFKPINDSLGHAAGDRVLAIIGARLAALLREGDLASRLGGDEFAMLLRDSDLATASL
VADRVIRAVAEKIILEGECVQVGASVGIAMGRPGRSRADELIHAADTAMYAAKRDGGSRAAIALPTPSTAADADDILGPR
DLGRPSATIAAVDVTNVADDHPGAPQLANPASATSASPAKLVEPAGSADLEPGRPLGSAVRKPPSARPWWWSRRSEAVRS
THRGEAAAPQRRAPQICFGRIVPLLVAALTLLGIASFGLWQESQALRAAEASAMRERLAQTARMADYMSAMQDPQPLVSA
ASAESWSPTDLTHNQTILQRFAQSPEGGPDTLASLVGLDGRTIAAEPAAAPPMPIATDSPQWQAVLAGRATTSQVVMVDG
VARLYTLAPVLEDGRPVAVLTLGRSARDALPSFFLAALGGMGLRDGGGAVVDRSGRASFSWNPGLAGRPLVNPADLADLR
MGKAERVTLVDDSNEIMLAAPIWSLDGAYFVFQQPATALFAGLREGQGLLAVSLFGTIGIAILGIAVSNARRENALRREE
SQLHALLHNAHDIVIVADRDCRITFASSDATGLLGQPTAGWIGKIFPDLSHPEDASRLRQFLGARDREGQGAIREIRLRA
CDGYRWFDIHASEPHHTPVLSGIVLTCHEIGGRRQMQAELAYRASHDPLTGLPNRAAFDRHLAAVAEHEQAGTSFAVLFI
DLDNFKPVNDRFGHAVGDDVLRVIGARIGAASRKTDMVSRLGGDEFAVLVDEADDDLVCAISARILETSRQPIALAGTTI
ALGATIGIALCRAGIDDPETALRNADNAMYRAKRAGRDRYALFTDRP

Sequences:

>Translated_1327_residues
MTMATRIFPVRRGSEDRRPKDRRFGDPPISGALGASDLRDLTRRGRLRRAMPLLVGLAAFLLLVAVIFAISSESLATSER
ERLSNRAHLTEQMAAYTSRAVDPQLQQSRVDAAGFSLTDQARNAHLLTSFRINPASDPNFVVALLDRDGHPLVSRPVSAT
IPVSALGDAWPTALAGQAARSPVFVIDGLVGRATVVPVGEGRPWAALVTVATDDLAQRFDEQLGSLELGPGGLTTVDSAG
VAASSWDPALVGRRVIDPEMLRGIPPLPARVWTSGHGSDEVTNIAAQQASSGYINLFQQRTDAFYSDLRAQQWSRNLTVI
AVGAVAMLGLVVFGLRREVSARRAGKRLDELLRNTRDLIAVVRLDGVVSFLSPSIERLLGSRASDWLGRPLAQLVHPADR
ERLDRLLTDGGAVLDVRLCGADGAIHWFDLEAADLPPRAGLAGVLVTCHEIGERKKLQDRLGHQARHDLLTGLANRSGFG
DRLASALAVSSESSCAVLYLDLDGFKPINDSLGHAAGDRVLAIIGARLAALLREGDLASRLGGDEFAMLLRDSDLATASL
VADRVIRAVAEKIILEGECVQVGASVGIAMGRPGRSRADELIHAADTAMYAAKRDGGSRAAIALPTPSTAADADDILGPR
DLGRPSATIAAVDVTNVADDHPGAPQLANPASATSASPAKLVEPAGSADLEPGRPLGSAVRKPPSARPWWWSRRSEAVRS
THRGEAAAPQRRAPQICFGRIVPLLVAALTLLGIASFGLWQESQALRAAEASAMRERLAQTARMADYMSAMQDPQPLVSA
ASAESWSPTDLTHNQTILQRFAQSPEGGPDTLASLVGLDGRTIAAEPAAAPPMPIATDSPQWQAVLAGRATTSQVVMVDG
VARLYTLAPVLEDGRPVAVLTLGRSARDALPSFFLAALGGMGLRDGGGAVVDRSGRASFSWNPGLAGRPLVNPADLADLR
MGKAERVTLVDDSNEIMLAAPIWSLDGAYFVFQQPATALFAGLREGQGLLAVSLFGTIGIAILGIAVSNARRENALRREE
SQLHALLHNAHDIVIVADRDCRITFASSDATGLLGQPTAGWIGKIFPDLSHPEDASRLRQFLGARDREGQGAIREIRLRA
CDGYRWFDIHASEPHHTPVLSGIVLTCHEIGGRRQMQAELAYRASHDPLTGLPNRAAFDRHLAAVAEHEQAGTSFAVLFI
DLDNFKPVNDRFGHAVGDDVLRVIGARIGAASRKTDMVSRLGGDEFAVLVDEADDDLVCAISARILETSRQPIALAGTTI
ALGATIGIALCRAGIDDPETALRNADNAMYRAKRAGRDRYALFTDRP
>Mature_1326_residues
TMATRIFPVRRGSEDRRPKDRRFGDPPISGALGASDLRDLTRRGRLRRAMPLLVGLAAFLLLVAVIFAISSESLATSERE
RLSNRAHLTEQMAAYTSRAVDPQLQQSRVDAAGFSLTDQARNAHLLTSFRINPASDPNFVVALLDRDGHPLVSRPVSATI
PVSALGDAWPTALAGQAARSPVFVIDGLVGRATVVPVGEGRPWAALVTVATDDLAQRFDEQLGSLELGPGGLTTVDSAGV
AASSWDPALVGRRVIDPEMLRGIPPLPARVWTSGHGSDEVTNIAAQQASSGYINLFQQRTDAFYSDLRAQQWSRNLTVIA
VGAVAMLGLVVFGLRREVSARRAGKRLDELLRNTRDLIAVVRLDGVVSFLSPSIERLLGSRASDWLGRPLAQLVHPADRE
RLDRLLTDGGAVLDVRLCGADGAIHWFDLEAADLPPRAGLAGVLVTCHEIGERKKLQDRLGHQARHDLLTGLANRSGFGD
RLASALAVSSESSCAVLYLDLDGFKPINDSLGHAAGDRVLAIIGARLAALLREGDLASRLGGDEFAMLLRDSDLATASLV
ADRVIRAVAEKIILEGECVQVGASVGIAMGRPGRSRADELIHAADTAMYAAKRDGGSRAAIALPTPSTAADADDILGPRD
LGRPSATIAAVDVTNVADDHPGAPQLANPASATSASPAKLVEPAGSADLEPGRPLGSAVRKPPSARPWWWSRRSEAVRST
HRGEAAAPQRRAPQICFGRIVPLLVAALTLLGIASFGLWQESQALRAAEASAMRERLAQTARMADYMSAMQDPQPLVSAA
SAESWSPTDLTHNQTILQRFAQSPEGGPDTLASLVGLDGRTIAAEPAAAPPMPIATDSPQWQAVLAGRATTSQVVMVDGV
ARLYTLAPVLEDGRPVAVLTLGRSARDALPSFFLAALGGMGLRDGGGAVVDRSGRASFSWNPGLAGRPLVNPADLADLRM
GKAERVTLVDDSNEIMLAAPIWSLDGAYFVFQQPATALFAGLREGQGLLAVSLFGTIGIAILGIAVSNARRENALRREES
QLHALLHNAHDIVIVADRDCRITFASSDATGLLGQPTAGWIGKIFPDLSHPEDASRLRQFLGARDREGQGAIREIRLRAC
DGYRWFDIHASEPHHTPVLSGIVLTCHEIGGRRQMQAELAYRASHDPLTGLPNRAAFDRHLAAVAEHEQAGTSFAVLFID
LDNFKPVNDRFGHAVGDDVLRVIGARIGAASRKTDMVSRLGGDEFAVLVDEADDDLVCAISARILETSRQPIALAGTTIA
LGATIGIALCRAGIDDPETALRNADNAMYRAKRAGRDRYALFTDRP

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=300, Percent_Identity=32, Blast_Score=134, Evalue=4e-32,
Organism=Escherichia coli, GI1787541, Length=280, Percent_Identity=30.3571428571429, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87081881, Length=184, Percent_Identity=38.0434782608696, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787262, Length=187, Percent_Identity=33.1550802139037, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=35.7575757575758, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI87082007, Length=169, Percent_Identity=36.094674556213, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=37.8048780487805, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=32.7380952380952, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=37.037037037037, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=32.9032258064516, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 141282; Mature: 141151

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMATRIFPVRRGSEDRRPKDRRFGDPPISGALGASDLRDLTRRGRLRRAMPLLVGLAAF
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVAVIFAISSESLATSERERLSNRAHLTEQMAAYTSRAVDPQLQQSRVDAAGFSLTDQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHH
ARNAHLLTSFRINPASDPNFVVALLDRDGHPLVSRPVSATIPVSALGDAWPTALAGQAAR
CCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCHHHC
SPVFVIDGLVGRATVVPVGEGRPWAALVTVATDDLAQRFDEQLGSLELGPGGLTTVDSAG
CCEEEEECCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCEEECCCCCCEECCCC
VAASSWDPALVGRRVIDPEMLRGIPPLPARVWTSGHGSDEVTNIAAQQASSGYINLFQQR
CCCCCCCHHHHCCCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
TDAFYSDLRAQQWSRNLTVIAVGAVAMLGLVVFGLRREVSARRAGKRLDELLRNTRDLIA
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRLDGVVSFLSPSIERLLGSRASDWLGRPLAQLVHPADRERLDRLLTDGGAVLDVRLCG
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC
ADGAIHWFDLEAADLPPRAGLAGVLVTCHEIGERKKLQDRLGHQARHDLLTGLANRSGFG
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DRLASALAVSSESSCAVLYLDLDGFKPINDSLGHAAGDRVLAIIGARLAALLREGDLASR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHH
LGGDEFAMLLRDSDLATASLVADRVIRAVAEKIILEGECVQVGASVGIAMGRPGRSRADE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHCEEECCCCCHHHHH
LIHAADTAMYAAKRDGGSRAAIALPTPSTAADADDILGPRDLGRPSATIAAVDVTNVADD
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCHHCCCCCCEEEEEEECCCCCC
HPGAPQLANPASATSASPAKLVEPAGSADLEPGRPLGSAVRKPPSARPWWWSRRSEAVRS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHH
THRGEAAAPQRRAPQICFGRIVPLLVAALTLLGIASFGLWQESQALRAAEASAMRERLAQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TARMADYMSAMQDPQPLVSAASAESWSPTDLTHNQTILQRFAQSPEGGPDTLASLVGLDG
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCC
RTIAAEPAAAPPMPIATDSPQWQAVLAGRATTSQVVMVDGVARLYTLAPVLEDGRPVAVL
CEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEE
TLGRSARDALPSFFLAALGGMGLRDGGGAVVDRSGRASFSWNPGLAGRPLVNPADLADLR
EECCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
MGKAERVTLVDDSNEIMLAAPIWSLDGAYFVFQQPATALFAGLREGQGLLAVSLFGTIGI
CCCCCEEEEEECCCCEEEEECEECCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHH
AILGIAVSNARRENALRREESQLHALLHNAHDIVIVADRDCRITFASSDATGLLGQPTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCC
WIGKIFPDLSHPEDASRLRQFLGARDREGQGAIREIRLRACDGYRWFDIHASEPHHTPVL
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHH
SGIVLTCHEIGGRRQMQAELAYRASHDPLTGLPNRAAFDRHLAAVAEHEQAGTSFAVLFI
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEE
DLDNFKPVNDRFGHAVGDDVLRVIGARIGAASRKTDMVSRLGGDEFAVLVDEADDDLVCA
ECCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEH
ISARILETSRQPIALAGTTIALGATIGIALCRAGIDDPETALRNADNAMYRAKRAGRDRY
HHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCE
ALFTDRP
EEECCCC
>Mature Secondary Structure 
TMATRIFPVRRGSEDRRPKDRRFGDPPISGALGASDLRDLTRRGRLRRAMPLLVGLAAF
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVAVIFAISSESLATSERERLSNRAHLTEQMAAYTSRAVDPQLQQSRVDAAGFSLTDQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHH
ARNAHLLTSFRINPASDPNFVVALLDRDGHPLVSRPVSATIPVSALGDAWPTALAGQAAR
CCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCHHHC
SPVFVIDGLVGRATVVPVGEGRPWAALVTVATDDLAQRFDEQLGSLELGPGGLTTVDSAG
CCEEEEECCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCEEECCCCCCEECCCC
VAASSWDPALVGRRVIDPEMLRGIPPLPARVWTSGHGSDEVTNIAAQQASSGYINLFQQR
CCCCCCCHHHHCCCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
TDAFYSDLRAQQWSRNLTVIAVGAVAMLGLVVFGLRREVSARRAGKRLDELLRNTRDLIA
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRLDGVVSFLSPSIERLLGSRASDWLGRPLAQLVHPADRERLDRLLTDGGAVLDVRLCG
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC
ADGAIHWFDLEAADLPPRAGLAGVLVTCHEIGERKKLQDRLGHQARHDLLTGLANRSGFG
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DRLASALAVSSESSCAVLYLDLDGFKPINDSLGHAAGDRVLAIIGARLAALLREGDLASR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHH
LGGDEFAMLLRDSDLATASLVADRVIRAVAEKIILEGECVQVGASVGIAMGRPGRSRADE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHCEEECCCCCHHHHH
LIHAADTAMYAAKRDGGSRAAIALPTPSTAADADDILGPRDLGRPSATIAAVDVTNVADD
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCHHCCCCCCEEEEEEECCCCCC
HPGAPQLANPASATSASPAKLVEPAGSADLEPGRPLGSAVRKPPSARPWWWSRRSEAVRS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHH
THRGEAAAPQRRAPQICFGRIVPLLVAALTLLGIASFGLWQESQALRAAEASAMRERLAQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TARMADYMSAMQDPQPLVSAASAESWSPTDLTHNQTILQRFAQSPEGGPDTLASLVGLDG
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCC
RTIAAEPAAAPPMPIATDSPQWQAVLAGRATTSQVVMVDGVARLYTLAPVLEDGRPVAVL
CEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEE
TLGRSARDALPSFFLAALGGMGLRDGGGAVVDRSGRASFSWNPGLAGRPLVNPADLADLR
EECCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
MGKAERVTLVDDSNEIMLAAPIWSLDGAYFVFQQPATALFAGLREGQGLLAVSLFGTIGI
CCCCCEEEEEECCCCEEEEECEECCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHH
AILGIAVSNARRENALRREESQLHALLHNAHDIVIVADRDCRITFASSDATGLLGQPTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCC
WIGKIFPDLSHPEDASRLRQFLGARDREGQGAIREIRLRACDGYRWFDIHASEPHHTPVL
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHH
SGIVLTCHEIGGRRQMQAELAYRASHDPLTGLPNRAAFDRHLAAVAEHEQAGTSFAVLFI
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEE
DLDNFKPVNDRFGHAVGDDVLRVIGARIGAASRKTDMVSRLGGDEFAVLVDEADDDLVCA
ECCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEH
ISARILETSRQPIALAGTTIALGATIGIALCRAGIDDPETALRNADNAMYRAKRAGRDRY
HHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCE
ALFTDRP
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]