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The map label for this gene is aroE [H]

Identifier: 158318744

GI number: 158318744

Start: 8554402

End: 8555274

Strand: Reverse

Name: aroE [H]

Synonym: Franean1_7015

Alternate gene names: 158318744

Gene position: 8555274-8554402 (Counterclockwise)

Preceding gene: 158318745

Following gene: 158318741

Centisome position: 95.25

GC content: 68.27

Gene sequence:

>873_bases
GTGTCCGCGTCGTCCGACATCAACCCGTTAAACTTCCTCAGCATCCTCACCGGCTCCTTCGCTACGCCGGCAGGCGAGAA
CCCCACCGCGGCGATGATCGAGTCGGCCTATCGACACCACCGCATCGACGCGTGCTACATCAACTGCGAAGTCGCTCCCG
AGGCTCTGGGGGATGCCGTACGCGGGGCCCGCGCAATGGGGTGGGTCGGCTTCAACTGCTCGATCCCGCACAAGGTCGCG
GTGATCGAGCACCTCGACGGCCTCGGCGAATCCGCCACGATCATCGGCGCCGTCAACTGCGCCGTCCGCCGCGACGACGG
GTGGATCGGTGAGAACACCGACGGGCAGGGCTTCCTGACCTCGCTGCGCGCCCAGGTCGATCCCGCCGGGCAGCATGTCG
TCCTCTTCGGTGCTGGCGGGGCCGCCCGCGCGATCGCGGTCGAGACCGCGCTGGCCGGGGCGGCATCCATCACCGTGGTG
AACCGCGGCACCGGGCGCGGCCGTGAGCTGTCCCGGCTCATCGCGGCGAAGACACCCACGGCGGCCGAGTTCGTCCGGTG
GGACGGGCCGTATCAGGTACCCGAGTGGGCGAGCATCGTGGTGAACGCGACGTCGATCGGGTTGTTCCCAGACGCCGATG
CCCGGCTGAACCTCGACCTGGACAGCCTGCGGCCGCACATGCTGGTGGCCGATGTCATTCCCAACCCCCCGCGCACTCGG
CTGCAACGGGATGCGGCCGAGCGCGGCTGCGTTACCCTCGACGGACTGGGGATGCTGGTCAACCAGGGAGTCATCAGCAT
CCGGCACTGGCTCGGTGTGGACGTCGACCCAGCCGTGATGCGCGAGAGACTGGCAGAAATACTCGGATCTTGA

Upstream 100 bases:

>100_bases
CGGGAGAACAATCGGATCGAGTCCGATCACAGTCGGCTGAAAGCAAGGGGCCTGGCACGCTCCGCCTTCCCGCAACGCAA
CACCCCCACCTGGAGGATCG

Downstream 100 bases:

>100_bases
CGCATCAGCGTGTGGGACTCTGTTGCCCAATTCGACTACGCAGCGACTGCCGGAAGTGCTGTGCCGAGCGGCTCGCTCTC
CGAGGTGCCAGCCGCGTCCC

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSASSDINPLNFLSILTGSFATPAGENPTAAMIESAYRHHRIDACYINCEVAPEALGDAVRGARAMGWVGFNCSIPHKVA
VIEHLDGLGESATIIGAVNCAVRRDDGWIGENTDGQGFLTSLRAQVDPAGQHVVLFGAGGAARAIAVETALAGAASITVV
NRGTGRGRELSRLIAAKTPTAAEFVRWDGPYQVPEWASIVVNATSIGLFPDADARLNLDLDSLRPHMLVADVIPNPPRTR
LQRDAAERGCVTLDGLGMLVNQGVISIRHWLGVDVDPAVMRERLAEILGS

Sequences:

>Translated_290_residues
MSASSDINPLNFLSILTGSFATPAGENPTAAMIESAYRHHRIDACYINCEVAPEALGDAVRGARAMGWVGFNCSIPHKVA
VIEHLDGLGESATIIGAVNCAVRRDDGWIGENTDGQGFLTSLRAQVDPAGQHVVLFGAGGAARAIAVETALAGAASITVV
NRGTGRGRELSRLIAAKTPTAAEFVRWDGPYQVPEWASIVVNATSIGLFPDADARLNLDLDSLRPHMLVADVIPNPPRTR
LQRDAAERGCVTLDGLGMLVNQGVISIRHWLGVDVDPAVMRERLAEILGS
>Mature_289_residues
SASSDINPLNFLSILTGSFATPAGENPTAAMIESAYRHHRIDACYINCEVAPEALGDAVRGARAMGWVGFNCSIPHKVAV
IEHLDGLGESATIIGAVNCAVRRDDGWIGENTDGQGFLTSLRAQVDPAGQHVVLFGAGGAARAIAVETALAGAASITVVN
RGTGRGRELSRLIAAKTPTAAEFVRWDGPYQVPEWASIVVNATSIGLFPDADARLNLDLDSLRPHMLVADVIPNPPRTRL
QRDAAERGCVTLDGLGMLVNQGVISIRHWLGVDVDPAVMRERLAEILGS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=30.2583025830258, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789675, Length=227, Percent_Identity=31.7180616740088, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30662; Mature: 30531

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSDINPLNFLSILTGSFATPAGENPTAAMIESAYRHHRIDACYINCEVAPEALGDAV
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHH
RGARAMGWVGFNCSIPHKVAVIEHLDGLGESATIIGAVNCAVRRDDGWIGENTDGQGFLT
HCCHHHEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHH
SLRAQVDPAGQHVVLFGAGGAARAIAVETALAGAASITVVNRGTGRGRELSRLIAAKTPT
HHHHHCCCCCCEEEEEECCCCCHHEEHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCC
AAEFVRWDGPYQVPEWASIVVNATSIGLFPDADARLNLDLDSLRPHMLVADVIPNPPRTR
HHHHEECCCCCCCCCHHEEEEEEEEECCCCCCCCEEECCHHHCCCCEEEEECCCCCCHHH
LQRDAAERGCVTLDGLGMLVNQGVISIRHWLGVDVDPAVMRERLAEILGS
HHHHHHHCCCEEECCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASSDINPLNFLSILTGSFATPAGENPTAAMIESAYRHHRIDACYINCEVAPEALGDAV
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHH
RGARAMGWVGFNCSIPHKVAVIEHLDGLGESATIIGAVNCAVRRDDGWIGENTDGQGFLT
HCCHHHEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHH
SLRAQVDPAGQHVVLFGAGGAARAIAVETALAGAASITVVNRGTGRGRELSRLIAAKTPT
HHHHHCCCCCCEEEEEECCCCCHHEEHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCC
AAEFVRWDGPYQVPEWASIVVNATSIGLFPDADARLNLDLDSLRPHMLVADVIPNPPRTR
HHHHEECCCCCCCCCHHEEEEEEEEECCCCCCCCEEECCHHHCCCCEEEEECCCCCCHHH
LQRDAAERGCVTLDGLGMLVNQGVISIRHWLGVDVDPAVMRERLAEILGS
HHHHHHHCCCEEECCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA