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The map label for this gene is hesA1 [H]

Identifier: 158318601

GI number: 158318601

Start: 8374316

End: 8375245

Strand: Reverse

Name: hesA1 [H]

Synonym: Franean1_6869

Alternate gene names: 158318601

Gene position: 8375245-8374316 (Counterclockwise)

Preceding gene: 158318602

Following gene: 158318600

Centisome position: 93.24

GC content: 75.48

Gene sequence:

>930_bases
ATGATAGTGACCCGGCGTAGCTCTCCGCCGGCGTCCGGCCCGGTCGGTCCGGTCGATGCCCGCGGGGCGTCCGAGGCCGC
GGTGCCAGCAACGGCGCTGGCACCGACGGCGCTGGCCCCGGCACCGACACCGACAGCGCCGGCGCAGCGCAGCGGGGGAG
CGAGCCTGCCCGGTCGGTACGACCGGCAGCTCGACCTGCCGGGCTTCGGCCCGGCGGCCCAGGAGCGGCTGCGCGGCGCG
ACCGTGCTCGTGGCGGGCGTGGGCGGCGTCGGCGGGGCGGCCGCTACCTACCTCGCCGCCGCCGGGGTCGGCCGGCTGGT
CCTGGTCCACCCGGGCGCACTGGAGGAGCCCGACCTCAACCGGCAGACCCTGATGCGTCCCGAGTGGATCGGTGGCTCCC
GGGTGGCCTGCGCGGAGCAGACCCTGCGCGCGCACCACCCGGGAGTCGAGATCGTCGCGATCGACCGCGAGCTGTCCCAG
CTCCCCGAGCTGGGCCGCCTCGTCGCCGAGGCGGACGTCGTCGTGGACGCCCGCCACAACTTCCCCGACCGCTACCTGCT
CAACGACACCTGCGTGGCGGCCCGGACCCCGGCGGTCGTCGCCGCGATGAACGCGACCGAGGGCAACATGCTCGTCGTCC
GGCCCGGGTCGCCGTGCCTGCGCTGTGTCTTCACCGAGGGCGACCCGTCCTGGCAGCCGCTGGGTTTCACCGTCCTCGGC
GCCGTGTCCGGGATGGTCGGCTGCCTCGCCGCGACCGAGGCGATAAAGATCATATCCGGGTTCGGTGAGCCCGCGGCCGG
CAGGCTGCTCCAGTTCGACCTCTGGGACCTGGACTTCCAGGTGCTGCGGGCCCGGCGCGACCCGCACTGCCCGACCTGCG
GCGGACCGTCCGGCAGCGGCCAGCGACCCGGCCCCGGGGAGCCACAGTGA

Upstream 100 bases:

>100_bases
TGCCCGAGATCGGCCGCGTCGCCCTCGTCTCCTGACGGCGAACCCCGGCCCACCACACCGACCCCCCGACGGAACACACG
GACCAGTCATGGAGCGCAGC

Downstream 100 bases:

>100_bases
TCTACCTCGACCACAACGCGACCACGCCCGTCGACCCGCGGGTGGTCGAGGTGATGCTCCCGCTGTTCACCGAGCGGTTC
GCCAACCCGGCCAGCAAGCA

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIVTRRSSPPASGPVGPVDARGASEAAVPATALAPTALAPAPTPTAPAQRSGGASLPGRYDRQLDLPGFGPAAQERLRGA
TVLVAGVGGVGGAAATYLAAAGVGRLVLVHPGALEEPDLNRQTLMRPEWIGGSRVACAEQTLRAHHPGVEIVAIDRELSQ
LPELGRLVAEADVVVDARHNFPDRYLLNDTCVAARTPAVVAAMNATEGNMLVVRPGSPCLRCVFTEGDPSWQPLGFTVLG
AVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVLRARRDPHCPTCGGPSGSGQRPGPGEPQ

Sequences:

>Translated_309_residues
MIVTRRSSPPASGPVGPVDARGASEAAVPATALAPTALAPAPTPTAPAQRSGGASLPGRYDRQLDLPGFGPAAQERLRGA
TVLVAGVGGVGGAAATYLAAAGVGRLVLVHPGALEEPDLNRQTLMRPEWIGGSRVACAEQTLRAHHPGVEIVAIDRELSQ
LPELGRLVAEADVVVDARHNFPDRYLLNDTCVAARTPAVVAAMNATEGNMLVVRPGSPCLRCVFTEGDPSWQPLGFTVLG
AVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVLRARRDPHCPTCGGPSGSGQRPGPGEPQ
>Mature_309_residues
MIVTRRSSPPASGPVGPVDARGASEAAVPATALAPTALAPAPTPTAPAQRSGGASLPGRYDRQLDLPGFGPAAQERLRGA
TVLVAGVGGVGGAAATYLAAAGVGRLVLVHPGALEEPDLNRQTLMRPEWIGGSRVACAEQTLRAHHPGVEIVAIDRELSQ
LPELGRLVAEADVVVDARHNFPDRYLLNDTCVAARTPAVVAAMNATEGNMLVVRPGSPCLRCVFTEGDPSWQPLGFTVLG
AVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVLRARRDPHCPTCGGPSGSGQRPGPGEPQ

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=219, Percent_Identity=42.4657534246575, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1787048, Length=241, Percent_Identity=36.9294605809129, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI87082356, Length=244, Percent_Identity=35.655737704918, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540406, Length=243, Percent_Identity=32.0987654320988, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6321903, Length=210, Percent_Identity=30.4761904761905, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582879, Length=244, Percent_Identity=38.9344262295082, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 31841; Mature: 31841

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTRRSSPPASGPVGPVDARGASEAAVPATALAPTALAPAPTPTAPAQRSGGASLPGRY
CEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRQLDLPGFGPAAQERLRGATVLVAGVGGVGGAAATYLAAAGVGRLVLVHPGALEEPDLN
CCEECCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
RQTLMRPEWIGGSRVACAEQTLRAHHPGVEIVAIDRELSQLPELGRLVAEADVVVDARHN
HHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEECCCC
FPDRYLLNDTCVAARTPAVVAAMNATEGNMLVVRPGSPCLRCVFTEGDPSWQPLGFTVLG
CCCCEEECCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHH
AVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVLRARRDPHCPTCGGPSGSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHCCCCCCCCCCCCCCCC
QRPGPGEPQ
CCCCCCCCC
>Mature Secondary Structure
MIVTRRSSPPASGPVGPVDARGASEAAVPATALAPTALAPAPTPTAPAQRSGGASLPGRY
CEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRQLDLPGFGPAAQERLRGATVLVAGVGGVGGAAATYLAAAGVGRLVLVHPGALEEPDLN
CCEECCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
RQTLMRPEWIGGSRVACAEQTLRAHHPGVEIVAIDRELSQLPELGRLVAEADVVVDARHN
HHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEECCCC
FPDRYLLNDTCVAARTPAVVAAMNATEGNMLVVRPGSPCLRCVFTEGDPSWQPLGFTVLG
CCCCEEECCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHH
AVSGMVGCLAATEAIKIISGFGEPAAGRLLQFDLWDLDFQVLRARRDPHCPTCGGPSGSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHCCCCCCCCCCCCCCCC
QRPGPGEPQ
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8709854 [H]