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The map label for this gene is asd [H]

Identifier: 158318309

GI number: 158318309

Start: 7998592

End: 7999653

Strand: Direct

Name: asd [H]

Synonym: Franean1_6574

Alternate gene names: 158318309

Gene position: 7998592-7999653 (Clockwise)

Preceding gene: 158318308

Following gene: 158318316

Centisome position: 89.05

GC content: 74.11

Gene sequence:

>1062_bases
ATGGGTGGGACGTCCCAGCGGCCGACGCTGGCCGTGGTCGGCGCGACCGGCGCGGTGGGCACGGTGATGCTCGCGCTGCT
GACCGAGCGCCCCGACGTCTGGGGTGAGATCAGACTGGTGGCCTCCGCCCGCTCGGCCGGGCGCACGCTGCGGGTCCGCG
ACGAGGACGTCACCGTGCGGGCCCTGTCACCGGAGGTGTTCGACGGCGTCGACATCGCGGTCTTCGACGTGCCGGACGAG
GTCTCGGCCCAGTGGGCGCCGGTCGCCGCCGCCCGGGGCGCGATCGCGGTGGACAACTCCGGCGCCTTCCGGATGGACCC
GGATGTTCCCCTGGTCGTGCCCGAGGTGAACGCCGCGGCGGTGGCGGACCGCCCGCGCGGCATCATCGCGAACCCGAACT
GCACCACCCTGTCGATGATCGTCGCGGTCGGGGCGCTGCACCGGGCGTTCGGCCTCGAGTCGCTCTTCGCGACGTCCTAC
CAGGCCGCGAGCGGGGCCGGCCAGGAGGGCATCGACACCCTCTACGCGCAGCTCGCCCTGGTCGGGGGCACCAGCGAGCT
GGGGCAGAACGCCGGCGACGTGCGCAAGGCCGTCGGCGAGGAGGGCCTGGGCCCGTTCCCCGCGCCGCTGGCGCTGAACG
TGGTGCCCTGGGCCGGCTCGCTGAGGGACGGCGGCTGGTCGTCGGAGGAACTCAAGATCCGCAACGAGTCACGGAAGATC
CTCGGCATGCCCGGGCTGCGCGTCTCGGCGACCTGTGTGCGCGTGCCCGTGGTCACGACGCACGCGGTGGCGGTGCACGC
CCGGTTCGTGCGGCCGGTCACGGCCGAGCAGGCGCGGGACGTCCTGGCGTCAGCGCCGGGCGTGGCCGTGCTCGACGATC
CCGCCGCGGGCGAGTTCCCGACGCCGGCGGATGTGGTGGGCACCGACCCGACCTGGGTCGGGCGGATCCGTCAGTCGCCC
GACGATCCGCACGAGGTCGCGTTGTTCGTGTGCGGGGACAACCTGCGCAAGGGCGCGGCGCTCAACACGCTGCAGATCGC
GGAGCTGCTCGCGGCCGACTGA

Upstream 100 bases:

>100_bases
TGGCCGTGCGCGCCGTGCACGCCGCCTTCGAGCTGGGCAACCCGGACGAGTCCGCCGTGGTGTACGCGGGAACCGGCCGA
TGAGCGAGCGGAGTCAGGGC

Downstream 100 bases:

>100_bases
CGCCGAGGGAGATCGATTCGCGACCTGCGTGGACGCGGGTATCGACGCGGGGCGTGAACCTCTCGCAACACGGAGCATCG
CGCGACTCTCGCCGGGGCGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGGTSQRPTLAVVGATGAVGTVMLALLTERPDVWGEIRLVASARSAGRTLRVRDEDVTVRALSPEVFDGVDIAVFDVPDE
VSAQWAPVAAARGAIAVDNSGAFRMDPDVPLVVPEVNAAAVADRPRGIIANPNCTTLSMIVAVGALHRAFGLESLFATSY
QAASGAGQEGIDTLYAQLALVGGTSELGQNAGDVRKAVGEEGLGPFPAPLALNVVPWAGSLRDGGWSSEELKIRNESRKI
LGMPGLRVSATCVRVPVVTTHAVAVHARFVRPVTAEQARDVLASAPGVAVLDDPAAGEFPTPADVVGTDPTWVGRIRQSP
DDPHEVALFVCGDNLRKGAALNTLQIAELLAAD

Sequences:

>Translated_353_residues
MGGTSQRPTLAVVGATGAVGTVMLALLTERPDVWGEIRLVASARSAGRTLRVRDEDVTVRALSPEVFDGVDIAVFDVPDE
VSAQWAPVAAARGAIAVDNSGAFRMDPDVPLVVPEVNAAAVADRPRGIIANPNCTTLSMIVAVGALHRAFGLESLFATSY
QAASGAGQEGIDTLYAQLALVGGTSELGQNAGDVRKAVGEEGLGPFPAPLALNVVPWAGSLRDGGWSSEELKIRNESRKI
LGMPGLRVSATCVRVPVVTTHAVAVHARFVRPVTAEQARDVLASAPGVAVLDDPAAGEFPTPADVVGTDPTWVGRIRQSP
DDPHEVALFVCGDNLRKGAALNTLQIAELLAAD
>Mature_352_residues
GGTSQRPTLAVVGATGAVGTVMLALLTERPDVWGEIRLVASARSAGRTLRVRDEDVTVRALSPEVFDGVDIAVFDVPDEV
SAQWAPVAAARGAIAVDNSGAFRMDPDVPLVVPEVNAAAVADRPRGIIANPNCTTLSMIVAVGALHRAFGLESLFATSYQ
AASGAGQEGIDTLYAQLALVGGTSELGQNAGDVRKAVGEEGLGPFPAPLALNVVPWAGSLRDGGWSSEELKIRNESRKIL
GMPGLRVSATCVRVPVVTTHAVAVHARFVRPVTAEQARDVLASAPGVAVLDDPAAGEFPTPADVVGTDPTWVGRIRQSPD
DPHEVALFVCGDNLRKGAALNTLQIAELLAAD

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=352, Percent_Identity=35.5113636363636, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789841, Length=359, Percent_Identity=27.5766016713092, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=27.8772378516624, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36595; Mature: 36464

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGTSQRPTLAVVGATGAVGTVMLALLTERPDVWGEIRLVASARSAGRTLRVRDEDVTVR
CCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCCEEEEECCCEEEE
ALSPEVFDGVDIAVFDVPDEVSAQWAPVAAARGAIAVDNSGAFRMDPDVPLVVPEVNAAA
EECCHHHCCCEEEEEECCCHHCCCCCCHHHCCCEEEECCCCCEEECCCCCEEEECCCCCE
VADRPRGIIANPNCTTLSMIVAVGALHRAFGLESLFATSYQAASGAGQEGIDTLYAQLAL
ECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHE
VGGTSELGQNAGDVRKAVGEEGLGPFPAPLALNVVPWAGSLRDGGWSSEELKIRNESRKI
ECCCHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEE
LGMPGLRVSATCVRVPVVTTHAVAVHARFVRPVTAEQARDVLASAPGVAVLDDPAAGEFP
ECCCCCEEEEEEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCC
TPADVVGTDPTWVGRIRQSPDDPHEVALFVCGDNLRKGAALNTLQIAELLAAD
CCCCCCCCCCHHHHHHCCCCCCHHHEEEEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GGTSQRPTLAVVGATGAVGTVMLALLTERPDVWGEIRLVASARSAGRTLRVRDEDVTVR
CCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCCEEEEECCCEEEE
ALSPEVFDGVDIAVFDVPDEVSAQWAPVAAARGAIAVDNSGAFRMDPDVPLVVPEVNAAA
EECCHHHCCCEEEEEECCCHHCCCCCCHHHCCCEEEECCCCCEEECCCCCEEEECCCCCE
VADRPRGIIANPNCTTLSMIVAVGALHRAFGLESLFATSYQAASGAGQEGIDTLYAQLAL
ECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHE
VGGTSELGQNAGDVRKAVGEEGLGPFPAPLALNVVPWAGSLRDGGWSSEELKIRNESRKI
ECCCHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEE
LGMPGLRVSATCVRVPVVTTHAVAVHARFVRPVTAEQARDVLASAPGVAVLDDPAAGEFP
ECCCCCEEEEEEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCC
TPADVVGTDPTWVGRIRQSPDDPHEVALFVCGDNLRKGAALNTLQIAELLAAD
CCCCCCCCCCHHHHHHCCCCCCHHHEEEEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8100567 [H]