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The map label for this gene is ywqF [H]

Identifier: 158318281

GI number: 158318281

Start: 7961386

End: 7962858

Strand: Direct

Name: ywqF [H]

Synonym: Franean1_6546

Alternate gene names: 158318281

Gene position: 7961386-7962858 (Clockwise)

Preceding gene: 158318277

Following gene: 158318282

Centisome position: 88.64

GC content: 70.26

Gene sequence:

>1473_bases
ATGGACGAGCAGCGGGTAACTGGCGAGCAGTCGATAACTGTGATTGGTAGCGGATATCTTGGCGCCACGCATGCCGTATG
CATGGCCGAACTCGGTTGCCGGGTGCTGGCCGTCGACGTCGACACAGCGAAGGTGGCCCGGCTCGCGGGCGGTACGGCTC
CTTTCTTCGAGCCGGGTCTGGAACCACTGCTCCGCAAGAACCTTGAAACCGGCCGGCTGCGTTTCACCACGTCGTATGAC
GAGGTGGCCGAGTTCGGGGACGTGCACTTCCTGTGCGTGAACACACCACAGCGCGGCGACGGCTACGCGGCGGACCTGAG
CTACCTGGACGCCGCGGTGGCAGCGTTGGCACCACGGCTGCGGCGGGACTGTCTGGTCGTCGGAAAGTCCACGGTGCCGG
TGGGCACCGCTGCCGCCCTGGCGGGGAGGCTCGCGAGGCTGGCTCCGGTCGGGGAAGGCGCCGAGCTGGCCTGGAACCCG
GAGTTCCTTCGCGAGGGCTTCGGAGTGGAGGATTCTCTGCGGCCGGATCGGCTCGTGTTCGGGGTGACCTCGCTGGCGGC
CGAGACCCGGCTGCGGCGTGTCTTCGCGCCGATCATCGATGCGGGTGCACCGGTCATCGTCACCGACTACGCCACCGCTG
AACTGGTGAAGGTCGCCGCGAACTCCTTCCTGGCCACGAAGATCTCGTTCATCAACGCGATGGCGGAGGTGTGCGAGGCG
ACCGGAGCGGATGTGCTCACCCTGGCGGCGGCGCTTGGTCAGGATCCACGGATCGGCAGCCGGTTCCTGCGCCCGGGAGT
CGGCTTCGGCGGCGGCTGCCTACCGAAGGACATTCGTGCCTTCGTCGCCCGGGCCGACGAGCTCGGCGTCGGCCGGGCGC
TGTCGTTCCTCCGGGAGGTCGACACGATCAACCTGCGACGGCGGACACGGGTCGTGGACCTGGTCCGGGCAGCGGCCGGG
GCGAGCCTCGACGGGTGCCCGATCGCGGTCCTCGGCACCGCGTTCAAGCCGAACTCGGACGACGTACGCGACTCACCCGC
GCTCGACGTGGCGGCGACGTTGCACCGGCTCGGTGCAGCGGTGACGGTGTACGACCCGGCGGCCAACGACAACGCCCGCC
GGGTCCATCCAGAGCTGGGGTACGCGGATTCGGTGCCGGCGGCGGTCGCCGGCGCGGATGCTGTGGTGGTGCTCACCGAG
TGGGCCCAGTTCGCCGAGTTGGGCCCGGTGGAACTGGCGGGCCTCGTTCGCCGCCGGGCCGTCGTCGACGCTCGGCATTG
CCTCGACCGCGACCGCTGGCGCGACGCCGGCTGGGACTATCGCGCGCCGGGACGTCCCGCGGCCCTTCCCTGGGCACCGC
CGGCTGTACCCGCGCAGCGCGCCGCGCAGCCGCACTCGCCGTCCCAGCGACACTCGCAACCAAAGGTGCCCCCGCGGCTG
GCTGCCGGTCTCGCCACCGATCAATCATTCTGA

Upstream 100 bases:

>100_bases
GTGGGATGCTGCCGTGACCGCCTTCCTTTCTGGGCGGCGTGTCAGGAAGTAATGGAACGTCGGCGGTCGCGCCGAACGGG
ACAGCATGAATCGGGGCAGC

Downstream 100 bases:

>100_bases
CCACCGGACGGCTGGACGGCGGGTACCCCCGGGCAGATGCAAGTGGTCAGATGAGGGTGAAGGTCAGGTGAAGATGACGG
TCCGACTCGCCCGCACAGCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MDEQRVTGEQSITVIGSGYLGATHAVCMAELGCRVLAVDVDTAKVARLAGGTAPFFEPGLEPLLRKNLETGRLRFTTSYD
EVAEFGDVHFLCVNTPQRGDGYAADLSYLDAAVAALAPRLRRDCLVVGKSTVPVGTAAALAGRLARLAPVGEGAELAWNP
EFLREGFGVEDSLRPDRLVFGVTSLAAETRLRRVFAPIIDAGAPVIVTDYATAELVKVAANSFLATKISFINAMAEVCEA
TGADVLTLAAALGQDPRIGSRFLRPGVGFGGGCLPKDIRAFVARADELGVGRALSFLREVDTINLRRRTRVVDLVRAAAG
ASLDGCPIAVLGTAFKPNSDDVRDSPALDVAATLHRLGAAVTVYDPAANDNARRVHPELGYADSVPAAVAGADAVVVLTE
WAQFAELGPVELAGLVRRRAVVDARHCLDRDRWRDAGWDYRAPGRPAALPWAPPAVPAQRAAQPHSPSQRHSQPKVPPRL
AAGLATDQSF

Sequences:

>Translated_490_residues
MDEQRVTGEQSITVIGSGYLGATHAVCMAELGCRVLAVDVDTAKVARLAGGTAPFFEPGLEPLLRKNLETGRLRFTTSYD
EVAEFGDVHFLCVNTPQRGDGYAADLSYLDAAVAALAPRLRRDCLVVGKSTVPVGTAAALAGRLARLAPVGEGAELAWNP
EFLREGFGVEDSLRPDRLVFGVTSLAAETRLRRVFAPIIDAGAPVIVTDYATAELVKVAANSFLATKISFINAMAEVCEA
TGADVLTLAAALGQDPRIGSRFLRPGVGFGGGCLPKDIRAFVARADELGVGRALSFLREVDTINLRRRTRVVDLVRAAAG
ASLDGCPIAVLGTAFKPNSDDVRDSPALDVAATLHRLGAAVTVYDPAANDNARRVHPELGYADSVPAAVAGADAVVVLTE
WAQFAELGPVELAGLVRRRAVVDARHCLDRDRWRDAGWDYRAPGRPAALPWAPPAVPAQRAAQPHSPSQRHSQPKVPPRL
AAGLATDQSF
>Mature_490_residues
MDEQRVTGEQSITVIGSGYLGATHAVCMAELGCRVLAVDVDTAKVARLAGGTAPFFEPGLEPLLRKNLETGRLRFTTSYD
EVAEFGDVHFLCVNTPQRGDGYAADLSYLDAAVAALAPRLRRDCLVVGKSTVPVGTAAALAGRLARLAPVGEGAELAWNP
EFLREGFGVEDSLRPDRLVFGVTSLAAETRLRRVFAPIIDAGAPVIVTDYATAELVKVAANSFLATKISFINAMAEVCEA
TGADVLTLAAALGQDPRIGSRFLRPGVGFGGGCLPKDIRAFVARADELGVGRALSFLREVDTINLRRRTRVVDLVRAAAG
ASLDGCPIAVLGTAFKPNSDDVRDSPALDVAATLHRLGAAVTVYDPAANDNARRVHPELGYADSVPAAVAGADAVVVLTE
WAQFAELGPVELAGLVRRRAVVDARHCLDRDRWRDAGWDYRAPGRPAALPWAPPAVPAQRAAQPHSPSQRHSQPKVPPRL
AAGLATDQSF

Specific function: Catalyzes the conversion of UDP-glucose into UDP- glucuronate, one of the precursors of teichuronic acid [H]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=472, Percent_Identity=30.9322033898305, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI296040438, Length=377, Percent_Identity=31.2997347480106, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI296040443, Length=317, Percent_Identity=32.1766561514196, Blast_Score=159, Evalue=7e-39,
Organism=Escherichia coli, GI48994968, Length=434, Percent_Identity=29.7235023041475, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI1788340, Length=376, Percent_Identity=26.5957446808511, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=469, Percent_Identity=34.1151385927505, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI17136908, Length=459, Percent_Identity=31.3725490196078, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51858; Mature: 51858

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQRVTGEQSITVIGSGYLGATHAVCMAELGCRVLAVDVDTAKVARLAGGTAPFFEPGL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCCCH
EPLLRKNLETGRLRFTTSYDEVAEFGDVHFLCVNTPQRGDGYAADLSYLDAAVAALAPRL
HHHHHCCCCCCEEEEEECHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
RRDCLVVGKSTVPVGTAAALAGRLARLAPVGEGAELAWNPEFLREGFGVEDSLRPDRLVF
HHCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEH
GVTSLAAETRLRRVFAPIIDAGAPVIVTDYATAELVKVAANSFLATKISFINAMAEVCEA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGADVLTLAAALGQDPRIGSRFLRPGVGFGGGCLPKDIRAFVARADELGVGRALSFLREV
CCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
DTINLRRRTRVVDLVRAAAGASLDGCPIAVLGTAFKPNSDDVRDSPALDVAATLHRLGAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCE
VTVYDPAANDNARRVHPELGYADSVPAAVAGADAVVVLTEWAQFAELGPVELAGLVRRRA
EEEECCCCCCCCCEECCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHH
VVDARHCLDRDRWRDAGWDYRAPGRPAALPWAPPAVPAQRAAQPHSPSQRHSQPKVPPRL
HHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCHHH
AAGLATDQSF
HHCCCCCCCC
>Mature Secondary Structure
MDEQRVTGEQSITVIGSGYLGATHAVCMAELGCRVLAVDVDTAKVARLAGGTAPFFEPGL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCCCH
EPLLRKNLETGRLRFTTSYDEVAEFGDVHFLCVNTPQRGDGYAADLSYLDAAVAALAPRL
HHHHHCCCCCCEEEEEECHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
RRDCLVVGKSTVPVGTAAALAGRLARLAPVGEGAELAWNPEFLREGFGVEDSLRPDRLVF
HHCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEH
GVTSLAAETRLRRVFAPIIDAGAPVIVTDYATAELVKVAANSFLATKISFINAMAEVCEA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGADVLTLAAALGQDPRIGSRFLRPGVGFGGGCLPKDIRAFVARADELGVGRALSFLREV
CCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
DTINLRRRTRVVDLVRAAAGASLDGCPIAVLGTAFKPNSDDVRDSPALDVAATLHRLGAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCE
VTVYDPAANDNARRVHPELGYADSVPAAVAGADAVVVLTEWAQFAELGPVELAGLVRRRA
EEEECCCCCCCCCEECCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHH
VVDARHCLDRDRWRDAGWDYRAPGRPAALPWAPPAVPAQRAAQPHSPSQRHSQPKVPPRL
HHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCHHH
AAGLATDQSF
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]