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The map label for this gene is ddc [H]

Identifier: 158318270

GI number: 158318270

Start: 7945966

End: 7947390

Strand: Reverse

Name: ddc [H]

Synonym: Franean1_6535

Alternate gene names: 158318270

Gene position: 7947390-7945966 (Counterclockwise)

Preceding gene: 158318272

Following gene: 158318266

Centisome position: 88.48

GC content: 73.75

Gene sequence:

>1425_bases
GTGATCCTTTCGGCAGCGCTCCGGCGGGGACCTAGACTGCGCCGGGTGCACCCATTCGATGTGCCGATCTTCGGCGCGCA
GCGCCCGGAGCTTGTCCAGGCGGTGGTGGATTACGCCCGCACTCGGATGAGTCTGGATCCCGTCCCGCTGGACGGTCCGA
GCCCACCGGCCGAGCTGTCCGCGCGGGCCGGGCGCACGATCACCCCGGAGGGCATCGGTGGTCTCGCCGCGCTGCGGGTG
TTCGACGAGGTGCTGTCGCGTGCCTGTATATCGGCGGACCACCCGCGCAACCTCGCCTTCATCCCGGCGGCGCCGACCCG
GGCGGCGATCCTGTTCGACCTGGTGGTCGGCGCCTCGTCGATCTACGGCGGGAGCTGGCTGGAGGGCGGCGGTGCCGTCC
ACGCGGAGAACGAGGCGCTGCGCTGGCTGTCCGACCTTGTCGGCTTCCCGCCGGGGGCCGGCGGGGTGTTCGTCCAGGGC
GGGACGGTCGGCAACGTCTCGGCGCTCGTCGCCGCGCGGCACGCCGTCCGGGCGCGCCGGGCGGCCCGAGGGCTCCCTCA
GCCGCCGCGCTGGCGGTTCCTGTGCGGCTCCGAGGCGCACTCCTCGCTGCGCCAGGCGGCCGAGGTCATGGACGTCGACC
TGGTGGTCGTCCCGACCGGCGACGACGGGCGGCTGACCGGCGGGGCGGTGGCCACCGCGCTCGACGAGCTCGCCGGCGAC
GGCGGGGTGTTCGCCGTGGTGGCCACGGCCGGCAGCACCCAGTTCGGGATCGTCGACGACATCCGCGGTGTCGTCGACGC
CTGCCGCCGGCACGACGTGTGGGTCCACGTCGACGGGGCCTACGGCCTCGCGGGCGCCGCCGCCGCGTCCGTGCGGCACC
TGTTCGACGGCATCGAGGAGACCGACTCCTTCATCGTCGACCCGCACAAGTGGCTGTTCGCGCCGTTCGACGCCTGCGCG
CTGGTGTACCGCGACCCGGCCGCGGCCCGCGCCGCCCACGCGCAGCAGGCGGGCTATCTGGAGGTGCTCGACACGCCGGG
GGCCTGGAACCCCTCGGACTACGAGGTCGGGCTCTCCCGGCGGGCCCGCGGCCTGCCGTTCTGGTTCTCGCTCGCCACCT
ACGGGACACATGCGTACGGTTCCGCGGTCGAGCGCTGCCTGGCGACGGCGCGGACGGCGGCCGACCACATCCGGGCCCTG
CCGTTCGTGGAGCTCGTGCGCGAGCCGGAGCTCTCGGTCGTCGTGTTCCGCCGGCTGGGCTGGCCGGCCGAGAGCTATCA
CCGGTGGACGGAACGCCTGCTCGCCGAAGGGCTCGCGTTCGTGACCCCGACCGTGCACCGGCAGGAGACGGTGACCCGGT
TCGCGATCGTCAATCCGGCGACCACACCGGAGGACATCGACCTGATTCTCGCCACCATGGCCTGA

Upstream 100 bases:

>100_bases
CAGGGCCCGGTTGTTTTCTGATTTTTTTCCGGCATTCACCCGCCGGGTGTCTCCCGGTATTCGCCGGTGATCGGTGGATT
ACCCCGGTGCGCGCGCCGGT

Downstream 100 bases:

>100_bases
ACGCCTGAACACGCACATGGCCTTTACCGGCGATCGCCCATGGGCTTCACAAGCGATGCGGCCGGGCCTCCGGCCGGCGT
TCCGCCGGAGGCCCGGCTTT

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MILSAALRRGPRLRRVHPFDVPIFGAQRPELVQAVVDYARTRMSLDPVPLDGPSPPAELSARAGRTITPEGIGGLAALRV
FDEVLSRACISADHPRNLAFIPAAPTRAAILFDLVVGASSIYGGSWLEGGGAVHAENEALRWLSDLVGFPPGAGGVFVQG
GTVGNVSALVAARHAVRARRAARGLPQPPRWRFLCGSEAHSSLRQAAEVMDVDLVVVPTGDDGRLTGGAVATALDELAGD
GGVFAVVATAGSTQFGIVDDIRGVVDACRRHDVWVHVDGAYGLAGAAAASVRHLFDGIEETDSFIVDPHKWLFAPFDACA
LVYRDPAAARAAHAQQAGYLEVLDTPGAWNPSDYEVGLSRRARGLPFWFSLATYGTHAYGSAVERCLATARTAADHIRAL
PFVELVREPELSVVVFRRLGWPAESYHRWTERLLAEGLAFVTPTVHRQETVTRFAIVNPATTPEDIDLILATMA

Sequences:

>Translated_474_residues
MILSAALRRGPRLRRVHPFDVPIFGAQRPELVQAVVDYARTRMSLDPVPLDGPSPPAELSARAGRTITPEGIGGLAALRV
FDEVLSRACISADHPRNLAFIPAAPTRAAILFDLVVGASSIYGGSWLEGGGAVHAENEALRWLSDLVGFPPGAGGVFVQG
GTVGNVSALVAARHAVRARRAARGLPQPPRWRFLCGSEAHSSLRQAAEVMDVDLVVVPTGDDGRLTGGAVATALDELAGD
GGVFAVVATAGSTQFGIVDDIRGVVDACRRHDVWVHVDGAYGLAGAAAASVRHLFDGIEETDSFIVDPHKWLFAPFDACA
LVYRDPAAARAAHAQQAGYLEVLDTPGAWNPSDYEVGLSRRARGLPFWFSLATYGTHAYGSAVERCLATARTAADHIRAL
PFVELVREPELSVVVFRRLGWPAESYHRWTERLLAEGLAFVTPTVHRQETVTRFAIVNPATTPEDIDLILATMA
>Mature_474_residues
MILSAALRRGPRLRRVHPFDVPIFGAQRPELVQAVVDYARTRMSLDPVPLDGPSPPAELSARAGRTITPEGIGGLAALRV
FDEVLSRACISADHPRNLAFIPAAPTRAAILFDLVVGASSIYGGSWLEGGGAVHAENEALRWLSDLVGFPPGAGGVFVQG
GTVGNVSALVAARHAVRARRAARGLPQPPRWRFLCGSEAHSSLRQAAEVMDVDLVVVPTGDDGRLTGGAVATALDELAGD
GGVFAVVATAGSTQFGIVDDIRGVVDACRRHDVWVHVDGAYGLAGAAAASVRHLFDGIEETDSFIVDPHKWLFAPFDACA
LVYRDPAAARAAHAQQAGYLEVLDTPGAWNPSDYEVGLSRRARGLPFWFSLATYGTHAYGSAVERCLATARTAADHIRAL
PFVELVREPELSVVVFRRLGWPAESYHRWTERLLAEGLAFVTPTVHRQETVTRFAIVNPATTPEDIDLILATMA

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=357, Percent_Identity=26.6106442577031, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4503281, Length=380, Percent_Identity=27.8947368421053, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI132814448, Length=380, Percent_Identity=27.8947368421053, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI194294551, Length=363, Percent_Identity=28.6501377410468, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI92110055, Length=392, Percent_Identity=25.765306122449, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI58331246, Length=365, Percent_Identity=24.6575342465753, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI197276620, Length=410, Percent_Identity=23.6585365853659, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4503875, Length=410, Percent_Identity=23.6585365853659, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534817, Length=461, Percent_Identity=26.4642082429501, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17534819, Length=461, Percent_Identity=26.4642082429501, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17555682, Length=466, Percent_Identity=23.3905579399142, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71993062, Length=346, Percent_Identity=25.7225433526012, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71993058, Length=385, Percent_Identity=22.5974025974026, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI133931025, Length=398, Percent_Identity=25.6281407035176, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221476190, Length=390, Percent_Identity=27.6923076923077, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24585143, Length=390, Percent_Identity=27.6923076923077, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24652373, Length=387, Percent_Identity=27.6485788113695, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24585139, Length=390, Percent_Identity=27.6923076923077, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573972, Length=466, Percent_Identity=27.4678111587983, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24586044, Length=394, Percent_Identity=27.6649746192893, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136594, Length=290, Percent_Identity=28.2758620689655, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21356415, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24657193, Length=290, Percent_Identity=24.8275862068966, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24657185, Length=290, Percent_Identity=24.8275862068966, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24657188, Length=290, Percent_Identity=24.8275862068966, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI17136190, Length=390, Percent_Identity=24.6153846153846, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585135, Length=390, Percent_Identity=25.1282051282051, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 50629; Mature: 50629

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00392 DDC_GAD_HDC_YDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSAALRRGPRLRRVHPFDVPIFGAQRPELVQAVVDYARTRMSLDPVPLDGPSPPAELS
CCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ARAGRTITPEGIGGLAALRVFDEVLSRACISADHPRNLAFIPAAPTRAAILFDLVVGASS
HCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
IYGGSWLEGGGAVHAENEALRWLSDLVGFPPGAGGVFVQGGTVGNVSALVAARHAVRARR
HCCCCEECCCCCEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AARGLPQPPRWRFLCGSEAHSSLRQAAEVMDVDLVVVPTGDDGRLTGGAVATALDELAGD
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCC
GGVFAVVATAGSTQFGIVDDIRGVVDACRRHDVWVHVDGAYGLAGAAAASVRHLFDGIEE
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCHHH
TDSFIVDPHKWLFAPFDACALVYRDPAAARAAHAQQAGYLEVLDTPGAWNPSDYEVGLSR
CCCEEECCHHHEECCHHHHEEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHH
RARGLPFWFSLATYGTHAYGSAVERCLATARTAADHIRALPFVELVREPELSVVVFRRLG
CCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCC
WPAESYHRWTERLLAEGLAFVTPTVHRQETVTRFAIVNPATTPEDIDLILATMA
CCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHEEEEECCCCCCCCHHEEEEECC
>Mature Secondary Structure
MILSAALRRGPRLRRVHPFDVPIFGAQRPELVQAVVDYARTRMSLDPVPLDGPSPPAELS
CCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ARAGRTITPEGIGGLAALRVFDEVLSRACISADHPRNLAFIPAAPTRAAILFDLVVGASS
HCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
IYGGSWLEGGGAVHAENEALRWLSDLVGFPPGAGGVFVQGGTVGNVSALVAARHAVRARR
HCCCCEECCCCCEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AARGLPQPPRWRFLCGSEAHSSLRQAAEVMDVDLVVVPTGDDGRLTGGAVATALDELAGD
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCC
GGVFAVVATAGSTQFGIVDDIRGVVDACRRHDVWVHVDGAYGLAGAAAASVRHLFDGIEE
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCHHH
TDSFIVDPHKWLFAPFDACALVYRDPAAARAAHAQQAGYLEVLDTPGAWNPSDYEVGLSR
CCCEEECCHHHEECCHHHHEEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHH
RARGLPFWFSLATYGTHAYGSAVERCLATARTAADHIRALPFVELVREPELSVVVFRRLG
CCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCC
WPAESYHRWTERLLAEGLAFVTPTVHRQETVTRFAIVNPATTPEDIDLILATMA
CCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHEEEEECCCCCCCCHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8772175 [H]