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The map label for this gene is yegE [H]

Identifier: 158318171

GI number: 158318171

Start: 7821424

End: 7825668

Strand: Direct

Name: yegE [H]

Synonym: Franean1_6436

Alternate gene names: 158318171

Gene position: 7821424-7825668 (Clockwise)

Preceding gene: 158318168

Following gene: 158318172

Centisome position: 87.08

GC content: 75.69

Gene sequence:

>4245_bases
ATGACCATGGGCGACCGGCGACACCGGATGACGCCCGGCGACCGCGCTCGGCGGCGGGTCGAGCGGCGGCGGGTCAAGCG
TGAGCGCCGTTGGGCCAGGTGGTCGTTCGGCCGCGGCCGGCTGGCCTGCTGGCCGCTGGTCAGCGGGCTGATCGCGATCC
TCGCGCTGAGCGGGGTGGCGCTGGTCGGCGGCAGCCGCTGGCTGGCTGACATCGAACAGGACCGGCTGGCGAACCGGGTG
AGTCTGATCAGCAACCTGGCCACCTGGGAGTCGACGGTCGACGACCCGGCAGGCCTGCGGGCCGTCGTCGAGCGGACCGC
GTTCGACCCCCACGACCCGGCCCGCAACCACCAGCTCGCCGCCCAGTTCCAGATCACCCCCGGAGGCGACACCACACTGC
TGGTCGCGCTGCTCGACCGCGCCGGGACGCTCCTGTCCGTTCGGCCGGCTCAGGGTGCGGTGAGCGCCGGGGATCTCGGG
CCGGCCTGGTCGACGGCGTGGAGCGGCGGCAGCGCCGTCTCGCCGGTCTTCACGCTCAACGGGCAGGCGGCGCGGGCCAC
CGTCGTCCCGGTCGGCGGCCCGCGGCCCTGGGCGGTCCTGGTCAGCGTGTCCACCGAGGAGTCGAAGCGGCAGCTCGGCA
CCGGCATGGGCACGCTCCTCCGGTTACGCGGGCAGGGCGCCGTCTCCACCATCGACGCGCGTGGCATCGCTGTGGTCTCA
ACCGACCCCTCGCTGCCCGGGACCCGCGTGCTCGACCCCGCCGAGCTCAGCGCGGCCTGGCGCTCGACCAACCGCACCCG
GGTCTGGACGACCGGCGGCGAAGACGGCTACACCCACGTCGCCGCCGCCCAGCCGGCGACCGGGTACACGACCTACCTGG
TCCAGCCGACCGCGCAGCTCTACGCGGAACTACGGGAGCAGCGGTCGCACCGCAACATCACCCTGTTGGTGGTGACGATG
GCCGCGGTGCTCTCGATCGCGGTCGTCGGGCTGCACGAGGAGACCCGCGCCCGGCGCCGGCACGGGAAGCTGAGCTCGCT
GCTGGCCGCCACCCGCGACATCGTCATGACCGTCTCGGCCGCCGGCCGGCTCGAGTACGTCAGCCCCGCCGCGGCGACCC
GGCTCGGCCACGATCCCGCGGCGCTGCGCGGGCGGCCGCTGTCCGAGCTGATGCGCGGTGGCGACGCGGAACGGGTCGCC
GCGCTGCTCGACGAGCCGCTGCCGGCGACCGTGATGAACGTCCGGCTGCTGTCCGCCGCCGGGCACGAGCACTGGTTCGA
CGTGTCGGCCCGGCGCCTCGCCGACGAGACGGGCTCGCCACGGGCGATCCTGACCTTCCACTCGATCGAGCGGCGCAAGT
CCCTGCTCGACCAGCTCGGGTTCCAGGCCGGGCACGACCTGCTCACCGGGCTGGCGAACCGGGCGACCTTCGACGAGCGG
CTCGCCGGCGCCCTCGGCCACCAGCCGGCCGGCGGCGCGCTCGCCCTGCTGTACATCGACCTGGACCACTTCAAACCGAT
CAACGACACCTACGGGCACGCGGCCGGCGACCGGGTGCTGACCGTCGTGGCGAGCCGCCTCACCGGCACGGTCGGCGCCG
GGATCGCGGCCGGGCCCGACGCCGGGGCCGGGGCCGGGGCCGGGAGCACCGTCAGCCGGTTCGGCGGCGACGAGTTCGGC
ATCCTGCTGCCCGGGGCGGACGAGACCGCCGCGGGCGCGATCGCCGCCCGTGTCGTCGCCGCGCTCGGCGAGCCGATCGA
CCTGGACGAGACCCGCGTGACGGTCGCGGCCAGCGTCGGGGTCGCCGTCGCCCGCGGGACGTGCCGTCCCGAACAGCTGC
TGCGGGCCGCCGACCAGGCGATGTACCAGGCGAAGGCGGCCGGCCGGGCCCGGTACTCGATCGGCGTGGTGGCGGAGGCG
GAGCCCGACCCGTCCGAGGCGGCCGCGCCCACTCCCCCGATGACACCGGCGGCGTCCCAGGCGCCCGGGACGCCGGCCAC
GGGGAGCCCGTCCGTCTCGCCCCCGCCCGCCGCGCGCCCGTCCTCGCGGCGTCTGTCAGTCGCGCACCCGTCCGCCCGAC
GCCTGTCGATCCGGCGGCTGTCAGTCCGGCGGCCGTCGCCGCGGCGGCCGTCCGTCCGGCGCCGAGGGGGTACTCGCCCG
CCCGCTCCGCTGCGGCACCGGCTCGCGGCGGCGATCCCGTCCGCGACCGTCGTCGTGGTGCTGCTGGGGACCGTGACCGC
CGGGCTCGCGATGGAGACCACGGCGCGTGACAGGGCTCAGAAGCAGCGGATCGACGCCGGCGTCGAGCTCGTCACCCACG
TCGCCGAGTACGCCCATGCCCTGAGCGACCCCGGGCGCCTCACCGGGGTCATCTCGGAGATGCCCTGGCCGCTCGGGAAC
CCCGCCGCGCTGACCGAGGTGTTGCGGGTCATGGGGACCTCAGCCGTTGCCGGCCCGGGCTCGCTGCTGGCCGTCGTCGC
TCCCGATGGCCGGCCGATGGCGACCGAGCCGCCCGGTACGCCCGTGCCGATACCCGTCGGCGACGATCTCTGGTTCGACG
CCAGCCGCAAAGGGGCGCTCACCCCGATGATCCTCGTCAACGGCCGCTCCCGGATCTGCTCCATCGTGCCGATCCTGCGC
GGCGGGTCCGCGGTGGCGCAGCTACTGCTGTGCCCGACGAACGTGCTGCCCGCCGCCCGGACGCTGCGCTCCATGAACGG
CCTGTCCGGGGATCTCGGCCGGGGCGGCATCTCCGTGCTCGACGTGCACGGCCGGGCGGTGCTGTCCTGGGACGAGGCGC
TGGTCGGCAGGAAGCTGGTCGAACCGGCCGACCTCGAGCAGGTCCGCGACGGCACACCCGGCCTGGTGCGCTCGGCGAAC
CGGCCGGACACGACCGCCGTCGCCACGGCGATCCCGGGCGGCGGATACGTCCTGCTGGACCAGACCGCCGACCTGTTCCA
GCTGAGCCTGCTGGAGTACCGCTCGATCGGCGACGGGCTGCTCTTCGGGATCATCGGCGTCACCGTCATCGGGCTGGCCG
TGGCCAACCGGCGCCGGGAGCGCGCGGTGCGCCAGGACTTCGAGCAGCTCGACATGCTGCTGCACGGCGCGCACGACATC
GTCATCCTCCTCGACCGGAGCGGCCGGCTGGATTTCGTCAGCTCCGCGGCGGAACCGCTGCTCGGCCGGGACAGCCAGGA
GATGCTCGGCCACGACCTGCTGCGATACGTGCACCCGGAGGACCGGGCGGCGGTCCGAGAGTTCCTCGCCGGCCCGGCCG
GCGAGGCGGCGGACGGCCGGGCGCTGCAGGACATCCGGCTCGAGGCGCGTGACGGCAGCCACCGCTGGTTCGACATCGAG
GCGACGGCCTGCGCCCCGCGGCCGCCGGCCGCCCGCGCCCGGGGCCCGGTGCTGACCTGCCGGGAGATCGGGGAACGGCG
CGGCCTCACCGAGCAGCTGCGCCGGCGGGCCCGGCACGACCCGCTCACCGGGCTGCCCAACCGGGCCGCGCTGGCCGAGC
ACCTCGACGCGGTCGCGCGGCGCAGGACAGCGTACGCGGTCCTGCTCGTCGACCTGGACGATTTCAAGCCGGTCAACGAC
AGCTTCGGCCACGAGGTGGGCGATCATGTGCTGCGGGTGACCGCCACGCGCATCCGCCGGGTCCTGACCGGCGGCGACAC
TGACGGCGGGGGCGGCGCCAGCGGCGACAACAGCCCGCGCCAGCCTGATACGGCGCCCGCTCCCGGCGGTGCCGCGGGCG
CCGGGGAGCGGCCCCGTTTCCGCCGCCGCCCGTCGTCCTGGTTCGGCGGCGACCTGGGTGGATCATGGAACCTGCCGGAG
CAGGGTGAGGTCTTCCGCGTGGGCGGCGACGAGTTCGTCGCGGTGCTGGCCGGCCCTGCCACCGCGCTCGCGGGCGGGCT
GGACGTCGAGGCCGTGGCCCGGCAGACCGCCGACCAGATCACCGCGATCGTCCGGGAACCGATTCACGCGGGCGGGCGGC
TGGTGACGGTGGGCGCCACGGTGGGCGTCGCGCTGTCGCGGGGGGCGGCCGCTCCGGAGGCCGTCCTGCGCCTCGCGGAC
GCGGCGATGTATCAGGCGAAGCGGTCCAGGCTTGACGGCCGCCCTCCGGGCGAGCCGCTGCGCACCTCCCCGCCCGCCAG
GCCGCTGCGCGCCCCCGGCACCGAGCCAGCCCCCGGCACCGAGGCCGCAACGCCAGCGGGCACCGAGGCCGAGCACGCGT
TGTGA

Upstream 100 bases:

>100_bases
CCTGCCGGGATTCGACGGATCAAAACCGAATACCGTCACCAAACACGGTCCCGGCGGAGTGCCGCCGCATCGGCAGCGGC
GGGGGAATGGAAACTGGCGG

Downstream 100 bases:

>100_bases
CGAAAACCCGGAACATCGGAAATGCAACTTCTCCGGTTACGCCGTCCGGTGTCAGGGTCGTGCCGTATGGTGGCGCCGTT
CGGGCTGACAGGCGGCGAGA

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 1414; Mature: 1413

Protein sequence:

>1414_residues
MTMGDRRHRMTPGDRARRRVERRRVKRERRWARWSFGRGRLACWPLVSGLIAILALSGVALVGGSRWLADIEQDRLANRV
SLISNLATWESTVDDPAGLRAVVERTAFDPHDPARNHQLAAQFQITPGGDTTLLVALLDRAGTLLSVRPAQGAVSAGDLG
PAWSTAWSGGSAVSPVFTLNGQAARATVVPVGGPRPWAVLVSVSTEESKRQLGTGMGTLLRLRGQGAVSTIDARGIAVVS
TDPSLPGTRVLDPAELSAAWRSTNRTRVWTTGGEDGYTHVAAAQPATGYTTYLVQPTAQLYAELREQRSHRNITLLVVTM
AAVLSIAVVGLHEETRARRRHGKLSSLLAATRDIVMTVSAAGRLEYVSPAAATRLGHDPAALRGRPLSELMRGGDAERVA
ALLDEPLPATVMNVRLLSAAGHEHWFDVSARRLADETGSPRAILTFHSIERRKSLLDQLGFQAGHDLLTGLANRATFDER
LAGALGHQPAGGALALLYIDLDHFKPINDTYGHAAGDRVLTVVASRLTGTVGAGIAAGPDAGAGAGAGSTVSRFGGDEFG
ILLPGADETAAGAIAARVVAALGEPIDLDETRVTVAASVGVAVARGTCRPEQLLRAADQAMYQAKAAGRARYSIGVVAEA
EPDPSEAAAPTPPMTPAASQAPGTPATGSPSVSPPPAARPSSRRLSVAHPSARRLSIRRLSVRRPSPRRPSVRRRGGTRP
PAPLRHRLAAAIPSATVVVVLLGTVTAGLAMETTARDRAQKQRIDAGVELVTHVAEYAHALSDPGRLTGVISEMPWPLGN
PAALTEVLRVMGTSAVAGPGSLLAVVAPDGRPMATEPPGTPVPIPVGDDLWFDASRKGALTPMILVNGRSRICSIVPILR
GGSAVAQLLLCPTNVLPAARTLRSMNGLSGDLGRGGISVLDVHGRAVLSWDEALVGRKLVEPADLEQVRDGTPGLVRSAN
RPDTTAVATAIPGGGYVLLDQTADLFQLSLLEYRSIGDGLLFGIIGVTVIGLAVANRRRERAVRQDFEQLDMLLHGAHDI
VILLDRSGRLDFVSSAAEPLLGRDSQEMLGHDLLRYVHPEDRAAVREFLAGPAGEAADGRALQDIRLEARDGSHRWFDIE
ATACAPRPPAARARGPVLTCREIGERRGLTEQLRRRARHDPLTGLPNRAALAEHLDAVARRRTAYAVLLVDLDDFKPVND
SFGHEVGDHVLRVTATRIRRVLTGGDTDGGGGASGDNSPRQPDTAPAPGGAAGAGERPRFRRRPSSWFGGDLGGSWNLPE
QGEVFRVGGDEFVAVLAGPATALAGGLDVEAVARQTADQITAIVREPIHAGGRLVTVGATVGVALSRGAAAPEAVLRLAD
AAMYQAKRSRLDGRPPGEPLRTSPPARPLRAPGTEPAPGTEAATPAGTEAEHAL

Sequences:

>Translated_1414_residues
MTMGDRRHRMTPGDRARRRVERRRVKRERRWARWSFGRGRLACWPLVSGLIAILALSGVALVGGSRWLADIEQDRLANRV
SLISNLATWESTVDDPAGLRAVVERTAFDPHDPARNHQLAAQFQITPGGDTTLLVALLDRAGTLLSVRPAQGAVSAGDLG
PAWSTAWSGGSAVSPVFTLNGQAARATVVPVGGPRPWAVLVSVSTEESKRQLGTGMGTLLRLRGQGAVSTIDARGIAVVS
TDPSLPGTRVLDPAELSAAWRSTNRTRVWTTGGEDGYTHVAAAQPATGYTTYLVQPTAQLYAELREQRSHRNITLLVVTM
AAVLSIAVVGLHEETRARRRHGKLSSLLAATRDIVMTVSAAGRLEYVSPAAATRLGHDPAALRGRPLSELMRGGDAERVA
ALLDEPLPATVMNVRLLSAAGHEHWFDVSARRLADETGSPRAILTFHSIERRKSLLDQLGFQAGHDLLTGLANRATFDER
LAGALGHQPAGGALALLYIDLDHFKPINDTYGHAAGDRVLTVVASRLTGTVGAGIAAGPDAGAGAGAGSTVSRFGGDEFG
ILLPGADETAAGAIAARVVAALGEPIDLDETRVTVAASVGVAVARGTCRPEQLLRAADQAMYQAKAAGRARYSIGVVAEA
EPDPSEAAAPTPPMTPAASQAPGTPATGSPSVSPPPAARPSSRRLSVAHPSARRLSIRRLSVRRPSPRRPSVRRRGGTRP
PAPLRHRLAAAIPSATVVVVLLGTVTAGLAMETTARDRAQKQRIDAGVELVTHVAEYAHALSDPGRLTGVISEMPWPLGN
PAALTEVLRVMGTSAVAGPGSLLAVVAPDGRPMATEPPGTPVPIPVGDDLWFDASRKGALTPMILVNGRSRICSIVPILR
GGSAVAQLLLCPTNVLPAARTLRSMNGLSGDLGRGGISVLDVHGRAVLSWDEALVGRKLVEPADLEQVRDGTPGLVRSAN
RPDTTAVATAIPGGGYVLLDQTADLFQLSLLEYRSIGDGLLFGIIGVTVIGLAVANRRRERAVRQDFEQLDMLLHGAHDI
VILLDRSGRLDFVSSAAEPLLGRDSQEMLGHDLLRYVHPEDRAAVREFLAGPAGEAADGRALQDIRLEARDGSHRWFDIE
ATACAPRPPAARARGPVLTCREIGERRGLTEQLRRRARHDPLTGLPNRAALAEHLDAVARRRTAYAVLLVDLDDFKPVND
SFGHEVGDHVLRVTATRIRRVLTGGDTDGGGGASGDNSPRQPDTAPAPGGAAGAGERPRFRRRPSSWFGGDLGGSWNLPE
QGEVFRVGGDEFVAVLAGPATALAGGLDVEAVARQTADQITAIVREPIHAGGRLVTVGATVGVALSRGAAAPEAVLRLAD
AAMYQAKRSRLDGRPPGEPLRTSPPARPLRAPGTEPAPGTEAATPAGTEAEHAL
>Mature_1413_residues
TMGDRRHRMTPGDRARRRVERRRVKRERRWARWSFGRGRLACWPLVSGLIAILALSGVALVGGSRWLADIEQDRLANRVS
LISNLATWESTVDDPAGLRAVVERTAFDPHDPARNHQLAAQFQITPGGDTTLLVALLDRAGTLLSVRPAQGAVSAGDLGP
AWSTAWSGGSAVSPVFTLNGQAARATVVPVGGPRPWAVLVSVSTEESKRQLGTGMGTLLRLRGQGAVSTIDARGIAVVST
DPSLPGTRVLDPAELSAAWRSTNRTRVWTTGGEDGYTHVAAAQPATGYTTYLVQPTAQLYAELREQRSHRNITLLVVTMA
AVLSIAVVGLHEETRARRRHGKLSSLLAATRDIVMTVSAAGRLEYVSPAAATRLGHDPAALRGRPLSELMRGGDAERVAA
LLDEPLPATVMNVRLLSAAGHEHWFDVSARRLADETGSPRAILTFHSIERRKSLLDQLGFQAGHDLLTGLANRATFDERL
AGALGHQPAGGALALLYIDLDHFKPINDTYGHAAGDRVLTVVASRLTGTVGAGIAAGPDAGAGAGAGSTVSRFGGDEFGI
LLPGADETAAGAIAARVVAALGEPIDLDETRVTVAASVGVAVARGTCRPEQLLRAADQAMYQAKAAGRARYSIGVVAEAE
PDPSEAAAPTPPMTPAASQAPGTPATGSPSVSPPPAARPSSRRLSVAHPSARRLSIRRLSVRRPSPRRPSVRRRGGTRPP
APLRHRLAAAIPSATVVVVLLGTVTAGLAMETTARDRAQKQRIDAGVELVTHVAEYAHALSDPGRLTGVISEMPWPLGNP
AALTEVLRVMGTSAVAGPGSLLAVVAPDGRPMATEPPGTPVPIPVGDDLWFDASRKGALTPMILVNGRSRICSIVPILRG
GSAVAQLLLCPTNVLPAARTLRSMNGLSGDLGRGGISVLDVHGRAVLSWDEALVGRKLVEPADLEQVRDGTPGLVRSANR
PDTTAVATAIPGGGYVLLDQTADLFQLSLLEYRSIGDGLLFGIIGVTVIGLAVANRRRERAVRQDFEQLDMLLHGAHDIV
ILLDRSGRLDFVSSAAEPLLGRDSQEMLGHDLLRYVHPEDRAAVREFLAGPAGEAADGRALQDIRLEARDGSHRWFDIEA
TACAPRPPAARARGPVLTCREIGERRGLTEQLRRRARHDPLTGLPNRAALAEHLDAVARRRTAYAVLLVDLDDFKPVNDS
FGHEVGDHVLRVTATRIRRVLTGGDTDGGGGASGDNSPRQPDTAPAPGGAAGAGERPRFRRRPSSWFGGDLGGSWNLPEQ
GEVFRVGGDEFVAVLAGPATALAGGLDVEAVARQTADQITAIVREPIHAGGRLVTVGATVGVALSRGAAAPEAVLRLADA
AMYQAKRSRLDGRPPGEPLRTSPPARPLRAPGTEPAPGTEAATPAGTEAEHAL

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=215, Percent_Identity=33.4883720930233, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI87082007, Length=198, Percent_Identity=36.8686868686869, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=186, Percent_Identity=35.4838709677419, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788956, Length=216, Percent_Identity=34.7222222222222, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI1787541, Length=191, Percent_Identity=30.3664921465969, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI145693134, Length=183, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787802, Length=208, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=32.4022346368715, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1787816, Length=218, Percent_Identity=29.3577981651376, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=29.7142857142857, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1787056, Length=168, Percent_Identity=33.9285714285714, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 148792; Mature: 148661

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMGDRRHRMTPGDRARRRVERRRVKRERRWARWSFGRGRLACWPLVSGLIAILALSGVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCHH
LVGGSRWLADIEQDRLANRVSLISNLATWESTVDDPAGLRAVVERTAFDPHDPARNHQLA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
AQFQITPGGDTTLLVALLDRAGTLLSVRPAQGAVSAGDLGPAWSTAWSGGSAVSPVFTLN
EEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEC
GQAARATVVPVGGPRPWAVLVSVSTEESKRQLGTGMGTLLRLRGQGAVSTIDARGIAVVS
CCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCHHHHHEECCCCCEEEECCCCEEEEE
TDPSLPGTRVLDPAELSAAWRSTNRTRVWTTGGEDGYTHVAAAQPATGYTTYLVQPTAQL
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCEEEEECCHHHH
YAELREQRSHRNITLLVVTMAAVLSIAVVGLHEETRARRRHGKLSSLLAATRDIVMTVSA
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEC
AGRLEYVSPAAATRLGHDPAALRGRPLSELMRGGDAERVAALLDEPLPATVMNVRLLSAA
CCCEEECCCHHHHHCCCCCHHHCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHC
GHEHWFDVSARRLADETGSPRAILTFHSIERRKSLLDQLGFQAGHDLLTGLANRATFDER
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCHHHHH
LAGALGHQPAGGALALLYIDLDHFKPINDTYGHAAGDRVLTVVASRLTGTVGAGIAAGPD
HHHHHCCCCCCCEEEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AGAGAGAGSTVSRFGGDEFGILLPGADETAAGAIAARVVAALGEPIDLDETRVTVAASVG
CCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHC
VAVARGTCRPEQLLRAADQAMYQAKAAGRARYSIGVVAEAEPDPSEAAAPTPPMTPAASQ
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
APGTPATGSPSVSPPPAARPSSRRLSVAHPSARRLSIRRLSVRRPSPRRPSVRRRGGTRP
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
PAPLRHRLAAAIPSATVVVVLLGTVTAGLAMETTARDRAQKQRIDAGVELVTHVAEYAHA
CHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSDPGRLTGVISEMPWPLGNPAALTEVLRVMGTSAVAGPGSLLAVVAPDGRPMATEPPGT
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PVPIPVGDDLWFDASRKGALTPMILVNGRSRICSIVPILRGGSAVAQLLLCPTNVLPAAR
CCCCCCCCCCEECCCCCCCCCCEEEECCCHHHEEHHHHHCCCHHHHHHHHCCCCCHHHHH
TLRSMNGLSGDLGRGGISVLDVHGRAVLSWDEALVGRKLVEPADLEQVRDGTPGLVRSAN
HHHHHCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCHHHHHCCCCHHHCCCC
RPDTTAVATAIPGGGYVLLDQTADLFQLSLLEYRSIGDGLLFGIIGVTVIGLAVANRRRE
CCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RAVRQDFEQLDMLLHGAHDIVILLDRSGRLDFVSSAAEPLLGRDSQEMLGHDLLRYVHPE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DRAAVREFLAGPAGEAADGRALQDIRLEARDGSHRWFDIEATACAPRPPAARARGPVLTC
HHHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEHH
REIGERRGLTEQLRRRARHDPLTGLPNRAALAEHLDAVARRRTAYAVLLVDLDDFKPVND
HHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCH
SFGHEVGDHVLRVTATRIRRVLTGGDTDGGGGASGDNSPRQPDTAPAPGGAAGAGERPRF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RRRPSSWFGGDLGGSWNLPEQGEVFRVGGDEFVAVLAGPATALAGGLDVEAVARQTADQI
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCHHHHHCCCCHHHHHHHHHHHH
TAIVREPIHAGGRLVTVGATVGVALSRGAAAPEAVLRLADAAMYQAKRSRLDGRPPGEPL
HHHHHHHHHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RTSPPARPLRAPGTEPAPGTEAATPAGTEAEHAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMGDRRHRMTPGDRARRRVERRRVKRERRWARWSFGRGRLACWPLVSGLIAILALSGVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCHH
LVGGSRWLADIEQDRLANRVSLISNLATWESTVDDPAGLRAVVERTAFDPHDPARNHQLA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
AQFQITPGGDTTLLVALLDRAGTLLSVRPAQGAVSAGDLGPAWSTAWSGGSAVSPVFTLN
EEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEC
GQAARATVVPVGGPRPWAVLVSVSTEESKRQLGTGMGTLLRLRGQGAVSTIDARGIAVVS
CCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCHHHHHEECCCCCEEEECCCCEEEEE
TDPSLPGTRVLDPAELSAAWRSTNRTRVWTTGGEDGYTHVAAAQPATGYTTYLVQPTAQL
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCEEEEECCHHHH
YAELREQRSHRNITLLVVTMAAVLSIAVVGLHEETRARRRHGKLSSLLAATRDIVMTVSA
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEC
AGRLEYVSPAAATRLGHDPAALRGRPLSELMRGGDAERVAALLDEPLPATVMNVRLLSAA
CCCEEECCCHHHHHCCCCCHHHCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHC
GHEHWFDVSARRLADETGSPRAILTFHSIERRKSLLDQLGFQAGHDLLTGLANRATFDER
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCHHHHH
LAGALGHQPAGGALALLYIDLDHFKPINDTYGHAAGDRVLTVVASRLTGTVGAGIAAGPD
HHHHHCCCCCCCEEEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AGAGAGAGSTVSRFGGDEFGILLPGADETAAGAIAARVVAALGEPIDLDETRVTVAASVG
CCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHC
VAVARGTCRPEQLLRAADQAMYQAKAAGRARYSIGVVAEAEPDPSEAAAPTPPMTPAASQ
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
APGTPATGSPSVSPPPAARPSSRRLSVAHPSARRLSIRRLSVRRPSPRRPSVRRRGGTRP
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
PAPLRHRLAAAIPSATVVVVLLGTVTAGLAMETTARDRAQKQRIDAGVELVTHVAEYAHA
CHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSDPGRLTGVISEMPWPLGNPAALTEVLRVMGTSAVAGPGSLLAVVAPDGRPMATEPPGT
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PVPIPVGDDLWFDASRKGALTPMILVNGRSRICSIVPILRGGSAVAQLLLCPTNVLPAAR
CCCCCCCCCCEECCCCCCCCCCEEEECCCHHHEEHHHHHCCCHHHHHHHHCCCCCHHHHH
TLRSMNGLSGDLGRGGISVLDVHGRAVLSWDEALVGRKLVEPADLEQVRDGTPGLVRSAN
HHHHHCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCHHHHHCCCCHHHCCCC
RPDTTAVATAIPGGGYVLLDQTADLFQLSLLEYRSIGDGLLFGIIGVTVIGLAVANRRRE
CCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RAVRQDFEQLDMLLHGAHDIVILLDRSGRLDFVSSAAEPLLGRDSQEMLGHDLLRYVHPE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DRAAVREFLAGPAGEAADGRALQDIRLEARDGSHRWFDIEATACAPRPPAARARGPVLTC
HHHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEHH
REIGERRGLTEQLRRRARHDPLTGLPNRAALAEHLDAVARRRTAYAVLLVDLDDFKPVND
HHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCH
SFGHEVGDHVLRVTATRIRRVLTGGDTDGGGGASGDNSPRQPDTAPAPGGAAGAGERPRF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RRRPSSWFGGDLGGSWNLPEQGEVFRVGGDEFVAVLAGPATALAGGLDVEAVARQTADQI
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCHHHHHCCCCHHHHHHHHHHHH
TAIVREPIHAGGRLVTVGATVGVALSRGAAAPEAVLRLADAAMYQAKRSRLDGRPPGEPL
HHHHHHHHHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RTSPPARPLRAPGTEPAPGTEAATPAGTEAEHAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]