Click here to switch to the map view.

The map label for this gene is lysS [H]

Identifier: 158318146

GI number: 158318146

Start: 7782945

End: 7784435

Strand: Reverse

Name: lysS [H]

Synonym: Franean1_6411

Alternate gene names: 158318146

Gene position: 7784435-7782945 (Counterclockwise)

Preceding gene: 158318147

Following gene: 158318144

Centisome position: 86.67

GC content: 69.95

Gene sequence:

>1491_bases
ATGGCGACGGACGAGTCCACGGCGGGTCCCCGCTCCGGGTATCTCACCGACTCGGTGACCTCCGCCGCGGCCGCCGCCGC
GGACGGGACGGCCGTCCGCATCGCCGGCCGGGTGGTGCTCTGGCGACGCATGGGCGGGCTGGTCTTCGGCCACATCCAGG
ACCGCGCCGGCCGGGTCCAGGTGTCGCTGTCCCGGGACGAGCTCGGGGTCGAGACCTTCCAGGAGTGGGCCCGCGCCGTC
AAGATCGGCGACTTCGTCGGCGTCACCGGAACCCTCTACACCACCCGCCGTGGCGAGAGGACCGTCGGCGCCTCCGAGCT
CGTCGTCCTGAACCGCACGGTGCGCGCCCTCCCGGACAAGTGGCAGGGCCTGTCGAACGTCGAGGCCCGGCTGCGCCGGC
GCTACCTCGACCTGCTGGTGAACAACGACTCCCGGGAGCGGTTCCGCACCAGGGCCCGGACGATCTCCCGCATCCGCCGC
TTCCTCGACGACAACGACTTCCTCGAGGTCGAGACGCCGATGCTGCAGGAGGCGGCGTCGGGCGCGGCCGCCCGTCCCTT
CATCACCCACCACAACGCCCTTGGAGAGGACTTCTACCTGCGCATCTCGCCGGAGACGTTCCTCAAGCGGGTCGTCGTCG
GCTCCCTGGACCGTGTCTACGAGCTCGGCCGTAACTTCCGCAACGAGGGCATGGACCCCTCGCACCTGCAGGAGTTCACG
ATGCTCGAGTGGTACGCGGCCTACTGGGACTACCGCGACAACATGCGCTTCGTCCGCGAGATGATCCTGGCCGTCCTCGA
CGACGTCTTCGGTAGCCGGACGGTGACCTACGACGGCGTGAAGCTCGACTTCGGCGCCGACTGGCCCGAACTGGACTACC
GGGCCGAGGTCGCCCGGCGGACGGGCATCGACCTCACGGTCGTCCGTGATCTGCCGACCCTGCGGGCGCGCATCAGCGAG
CTGGGGCTCGAGGTCGACGACGCGGCCTCCTACGCGGGGCTCGTCGACCTGCTCTACAAGAAGGCCGTTCGCCCGCACCT
CGTCCAGCCGTGTTTCCTGGTGCACCATCCGGCGGAGCTCGTCCCGCTGGCCCGGCGCAGCGACGAAGACCCGTCCCGGC
TCGACATGTTCCAGGTTGTCGTGAACGGCTGGGAGCTGGTGAAGGCCTACTCCGAGCTCGTCGACCCGGTCGAGCAGCGC
CGCCGCCTCGAGGAGCAGGCCGAGCTGCGCGCCGCCGGCGACGACGAGACCATGATGCTGGAAGAGGACTTCATCGAGGC
GATGGAGTACGGGATGCCCCCGATGTCCGGGCTCGGCATCGGCATCGACCGCCTCATCGCCCTGCTCACCGATGCCCCGA
CGCTGCGGGAAGTAGTCCTGTTCCCGCTGATGCGAGACTCCCGCCGCGGCCAGACCGACCCAGCCGCCGGCAACGACGCG
AACGCCGCCGATACATCTGACGCGGCTGTCGCGGATCCAAGCGCCGGCTGA

Upstream 100 bases:

>100_bases
GTAGGCTTGACCATGCGGGCCGCGGGAACTGCGACGTGCGCGGCGCCGTCAAGACGCCTGGGATTCTCGGGCGGAAGCCT
CTCGCAAAAGGGTGTTGTGC

Downstream 100 bases:

>100_bases
CACGGGGGCACGTTGACCCGGGCGTCGGCTGACCCGAGTTGTGCTGACCTGAGCTGTGTTGACCCGAGTTGACACGCGGG
TTTGAAGCGTGTCCATACGG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MATDESTAGPRSGYLTDSVTSAAAAAADGTAVRIAGRVVLWRRMGGLVFGHIQDRAGRVQVSLSRDELGVETFQEWARAV
KIGDFVGVTGTLYTTRRGERTVGASELVVLNRTVRALPDKWQGLSNVEARLRRRYLDLLVNNDSRERFRTRARTISRIRR
FLDDNDFLEVETPMLQEAASGAAARPFITHHNALGEDFYLRISPETFLKRVVVGSLDRVYELGRNFRNEGMDPSHLQEFT
MLEWYAAYWDYRDNMRFVREMILAVLDDVFGSRTVTYDGVKLDFGADWPELDYRAEVARRTGIDLTVVRDLPTLRARISE
LGLEVDDAASYAGLVDLLYKKAVRPHLVQPCFLVHHPAELVPLARRSDEDPSRLDMFQVVVNGWELVKAYSELVDPVEQR
RRLEEQAELRAAGDDETMMLEEDFIEAMEYGMPPMSGLGIGIDRLIALLTDAPTLREVVLFPLMRDSRRGQTDPAAGNDA
NAADTSDAAVADPSAG

Sequences:

>Translated_496_residues
MATDESTAGPRSGYLTDSVTSAAAAAADGTAVRIAGRVVLWRRMGGLVFGHIQDRAGRVQVSLSRDELGVETFQEWARAV
KIGDFVGVTGTLYTTRRGERTVGASELVVLNRTVRALPDKWQGLSNVEARLRRRYLDLLVNNDSRERFRTRARTISRIRR
FLDDNDFLEVETPMLQEAASGAAARPFITHHNALGEDFYLRISPETFLKRVVVGSLDRVYELGRNFRNEGMDPSHLQEFT
MLEWYAAYWDYRDNMRFVREMILAVLDDVFGSRTVTYDGVKLDFGADWPELDYRAEVARRTGIDLTVVRDLPTLRARISE
LGLEVDDAASYAGLVDLLYKKAVRPHLVQPCFLVHHPAELVPLARRSDEDPSRLDMFQVVVNGWELVKAYSELVDPVEQR
RRLEEQAELRAAGDDETMMLEEDFIEAMEYGMPPMSGLGIGIDRLIALLTDAPTLREVVLFPLMRDSRRGQTDPAAGNDA
NAADTSDAAVADPSAG
>Mature_495_residues
ATDESTAGPRSGYLTDSVTSAAAAAADGTAVRIAGRVVLWRRMGGLVFGHIQDRAGRVQVSLSRDELGVETFQEWARAVK
IGDFVGVTGTLYTTRRGERTVGASELVVLNRTVRALPDKWQGLSNVEARLRRRYLDLLVNNDSRERFRTRARTISRIRRF
LDDNDFLEVETPMLQEAASGAAARPFITHHNALGEDFYLRISPETFLKRVVVGSLDRVYELGRNFRNEGMDPSHLQEFTM
LEWYAAYWDYRDNMRFVREMILAVLDDVFGSRTVTYDGVKLDFGADWPELDYRAEVARRTGIDLTVVRDLPTLRARISEL
GLEVDDAASYAGLVDLLYKKAVRPHLVQPCFLVHHPAELVPLARRSDEDPSRLDMFQVVVNGWELVKAYSELVDPVEQRR
RLEEQAELRAAGDDETMMLEEDFIEAMEYGMPPMSGLGIGIDRLIALLTDAPTLREVVLFPLMRDSRRGQTDPAAGNDAN
AADTSDAAVADPSAG

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI5031815, Length=450, Percent_Identity=37.5555555555556, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI194272210, Length=450, Percent_Identity=37.5555555555556, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI40789249, Length=323, Percent_Identity=25.077399380805, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1789256, Length=435, Percent_Identity=42.5287356321839, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1790571, Length=438, Percent_Identity=42.0091324200913, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI87082379, Length=324, Percent_Identity=33.641975308642, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788173, Length=302, Percent_Identity=30.794701986755, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17535925, Length=480, Percent_Identity=35.8333333333333, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71994340, Length=480, Percent_Identity=35.8333333333333, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17535927, Length=480, Percent_Identity=35.8333333333333, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17551876, Length=354, Percent_Identity=24.0112994350282, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566633, Length=173, Percent_Identity=28.3236994219653, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320242, Length=455, Percent_Identity=39.1208791208791, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6324256, Length=475, Percent_Identity=26.5263157894737, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323011, Length=464, Percent_Identity=22.6293103448276, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640849, Length=472, Percent_Identity=38.5593220338983, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24640851, Length=472, Percent_Identity=38.5593220338983, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24584738, Length=358, Percent_Identity=26.8156424581006, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136276, Length=464, Percent_Identity=22.198275862069, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 55618; Mature: 55486

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDESTAGPRSGYLTDSVTSAAAAAADGTAVRIAGRVVLWRRMGGLVFGHIQDRAGRVQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCEEE
VSLSRDELGVETFQEWARAVKIGDFVGVTGTLYTTRRGERTVGASELVVLNRTVRALPDK
EEECHHHCCHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCCCCHHEEEHHHHHHHCCHH
WQGLSNVEARLRRRYLDLLVNNDSRERFRTRARTISRIRRFLDDNDFLEVETPMLQEAAS
HCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHC
GAAARPFITHHNALGEDFYLRISPETFLKRVVVGSLDRVYELGRNFRNEGMDPSHLQEFT
CCCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLEWYAAYWDYRDNMRFVREMILAVLDDVFGSRTVTYDGVKLDFGADWPELDYRAEVARR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCCHHHHHHHH
TGIDLTVVRDLPTLRARISELGLEVDDAASYAGLVDLLYKKAVRPHLVQPCFLVHHPAEL
CCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCHHH
VPLARRSDEDPSRLDMFQVVVNGWELVKAYSELVDPVEQRRRLEEQAELRAAGDDETMML
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
EEDFIEAMEYGMPPMSGLGIGIDRLIALLTDAPTLREVVLFPLMRDSRRGQTDPAAGNDA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
NAADTSDAAVADPSAG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATDESTAGPRSGYLTDSVTSAAAAAADGTAVRIAGRVVLWRRMGGLVFGHIQDRAGRVQ
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCEEE
VSLSRDELGVETFQEWARAVKIGDFVGVTGTLYTTRRGERTVGASELVVLNRTVRALPDK
EEECHHHCCHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCCCCHHEEEHHHHHHHCCHH
WQGLSNVEARLRRRYLDLLVNNDSRERFRTRARTISRIRRFLDDNDFLEVETPMLQEAAS
HCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHC
GAAARPFITHHNALGEDFYLRISPETFLKRVVVGSLDRVYELGRNFRNEGMDPSHLQEFT
CCCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLEWYAAYWDYRDNMRFVREMILAVLDDVFGSRTVTYDGVKLDFGADWPELDYRAEVARR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCCHHHHHHHH
TGIDLTVVRDLPTLRARISELGLEVDDAASYAGLVDLLYKKAVRPHLVQPCFLVHHPAEL
CCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCHHH
VPLARRSDEDPSRLDMFQVVVNGWELVKAYSELVDPVEQRRRLEEQAELRAAGDDETMML
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
EEDFIEAMEYGMPPMSGLGIGIDRLIALLTDAPTLREVVLFPLMRDSRRGQTDPAAGNDA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
NAADTSDAAVADPSAG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA