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The map label for this gene is adh [H]

Identifier: 158317957

GI number: 158317957

Start: 7550546

End: 7551580

Strand: Reverse

Name: adh [H]

Synonym: Franean1_6217

Alternate gene names: 158317957

Gene position: 7551580-7550546 (Counterclockwise)

Preceding gene: 158317959

Following gene: 158317956

Centisome position: 84.07

GC content: 68.7

Gene sequence:

>1035_bases
ATGAGCCGGGCCATCGTTTTCAACGGCGACGAGACCTGGGAGGAACGCGATCTGCCGGTGCCCGATCCCCAGCCGGGCGG
AGCTGTCCTTCGGGTGGAGGCGACCGGCCTCTGCCACAGCGATATCGACCATTTCCGGGGTCATGTGCACACGTCCTGGG
GCGGTGCGTTCCCGTCCATCGCCGGTCACGAGATCGTGGGCCGGGTGGAGAAGATCGACGCCGCGGCGGCCGCCGCGTGG
GGCGTCGGGGAAGGTGACCGGGTCGCCGTCCGCGACATCGTGGTGACCCCCGCCGGTTACCGCATCTACGGGCACGACTT
CTCCGTGGACGAGGGCTCCGGCCTGCATGGCGGATTCGCGGAGCACCTCGAACTGCTGCCCGGTTCCCGGGTGTATCGCC
TGCGTGACGATCTCCCGGCCGAGGAGCTCACGGTCTTCGAGCCACTGAGCTGCGCGGTGACCTGGGTGGCGCCGGTGCGG
CAGGACGATGTCGTGATCATCGAAGGTCCCGGCCACATGGGCATGGCCACCATCGTCGCTGCCCGCGCGGCCGGAGCCGC
CACGGTGATCGTGACCGGGACGGCGAGCGACAGATTCCGCCTCGACTGGGCGCTGCGTGTCGGTGCCGACCACACCGTCG
ACGTCGACAACGAGGACCCGGTCGAACGAGTACACGAGATCACCGACGGCCGGATGGCGGACGTGGTGATCGACGCCGCG
GCGGGAAATCCGGTGACGGTGAACCTTGCCATGGATCTCGTGCACAAGGGTGGGCATGTCGTCGTCGCCGGTATGAAGGA
CGGCCCGCTCAAGGGCTTCCACAGCGACTGGATCCCTACCCGACGGATCACCCTCCACCCCGGCGCGGGCCTCGACACGG
AAGGAGCGGTCGAGCTCATCAACGCCGGCCGGGTACCGACCGCCGACCTGCTCGGCGACACCTTCCCCCTCGAACGTTTC
GAGGAGGCGTTCGCCCTCCTGTCACGAAGGACACCGGGCCACGATTCGATCCGGGTCGCCCTGCGCCTGTGCTGA

Upstream 100 bases:

>100_bases
GGCCATCCAACACCACCTTGACAGAATGCGTGCATTGTTCGCATACTTCATCGACCGAAAGGCGAACGGCGTACGCATCA
GAGGGCGTGGAGGTTCTCCC

Downstream 100 bases:

>100_bases
ACACCGCCGTCCCGGAAACCGCCGATGGGGAGGAACGAATGCCGGAGATCCGATGTTTCTCGCACGTCGGGATGACGGTG
GCAGACCTCGACTGTTCAGT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDAAAAAAW
GVGEGDRVAVRDIVVTPAGYRIYGHDFSVDEGSGLHGGFAEHLELLPGSRVYRLRDDLPAEELTVFEPLSCAVTWVAPVR
QDDVVIIEGPGHMGMATIVAARAAGAATVIVTGTASDRFRLDWALRVGADHTVDVDNEDPVERVHEITDGRMADVVIDAA
AGNPVTVNLAMDLVHKGGHVVVAGMKDGPLKGFHSDWIPTRRITLHPGAGLDTEGAVELINAGRVPTADLLGDTFPLERF
EEAFALLSRRTPGHDSIRVALRLC

Sequences:

>Translated_344_residues
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDAAAAAAW
GVGEGDRVAVRDIVVTPAGYRIYGHDFSVDEGSGLHGGFAEHLELLPGSRVYRLRDDLPAEELTVFEPLSCAVTWVAPVR
QDDVVIIEGPGHMGMATIVAARAAGAATVIVTGTASDRFRLDWALRVGADHTVDVDNEDPVERVHEITDGRMADVVIDAA
AGNPVTVNLAMDLVHKGGHVVVAGMKDGPLKGFHSDWIPTRRITLHPGAGLDTEGAVELINAGRVPTADLLGDTFPLERF
EEAFALLSRRTPGHDSIRVALRLC
>Mature_343_residues
SRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDAAAAAAWG
VGEGDRVAVRDIVVTPAGYRIYGHDFSVDEGSGLHGGFAEHLELLPGSRVYRLRDDLPAEELTVFEPLSCAVTWVAPVRQ
DDVVIIEGPGHMGMATIVAARAAGAATVIVTGTASDRFRLDWALRVGADHTVDVDNEDPVERVHEITDGRMADVVIDAAA
GNPVTVNLAMDLVHKGGHVVVAGMKDGPLKGFHSDWIPTRRITLHPGAGLDTEGAVELINAGRVPTADLLGDTFPLERFE
EAFALLSRRTPGHDSIRVALRLC

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788075, Length=340, Percent_Identity=25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788073, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790045, Length=267, Percent_Identity=23.5955056179775, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787863, Length=327, Percent_Identity=21.7125382262997, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=348, Percent_Identity=25.5747126436782, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36783; Mature: 36652

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSI
CCCEEEECCCCCHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCEEEECCCCCCCCC
AGHEIVGRVEKIDAAAAAAWGVGEGDRVAVRDIVVTPAGYRIYGHDFSVDEGSGLHGGFA
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCEECCCCCCCCCCCHH
EHLELLPGSRVYRLRDDLPAEELTVFEPLSCAVTWVAPVRQDDVVIIEGPGHMGMATIVA
HHHHHCCCCEEEEECCCCCHHHEEEECCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHH
ARAAGAATVIVTGTASDRFRLDWALRVGADHTVDVDNEDPVERVHEITDGRMADVVIDAA
HHCCCCEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHCCCCEEEEEEECC
AGNPVTVNLAMDLVHKGGHVVVAGMKDGPLKGFHSDWIPTRRITLHPGAGLDTEGAVELI
CCCCEEEEEEEEEHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHEE
NAGRVPTADLLGDTFPLERFEEAFALLSRRTPGHDSIRVALRLC
CCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSI
CCEEEECCCCCHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCEEEECCCCCCCCC
AGHEIVGRVEKIDAAAAAAWGVGEGDRVAVRDIVVTPAGYRIYGHDFSVDEGSGLHGGFA
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCEECCCCCCCCCCCHH
EHLELLPGSRVYRLRDDLPAEELTVFEPLSCAVTWVAPVRQDDVVIIEGPGHMGMATIVA
HHHHHCCCCEEEEECCCCCHHHEEEECCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHH
ARAAGAATVIVTGTASDRFRLDWALRVGADHTVDVDNEDPVERVHEITDGRMADVVIDAA
HHCCCCEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHCCCCEEEEEEECC
AGNPVTVNLAMDLVHKGGHVVVAGMKDGPLKGFHSDWIPTRRITLHPGAGLDTEGAVELI
CCCCEEEEEEEEEHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHEE
NAGRVPTADLLGDTFPLERFEEAFALLSRRTPGHDSIRVALRLC
CCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]