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The map label for this gene is mug [H]

Identifier: 158317797

GI number: 158317797

Start: 7367721

End: 7368614

Strand: Direct

Name: mug [H]

Synonym: Franean1_6055

Alternate gene names: 158317797

Gene position: 7367721-7368614 (Clockwise)

Preceding gene: 158317761

Following gene: 158317806

Centisome position: 82.03

GC content: 72.04

Gene sequence:

>894_bases
ATGGCCAGCACCAGACCGCCCAGCCAGGGCACCGCGCCGGACCAGCCGTCCCCGGCCGACCAGACACCAGAAGACACGCT
GCCGCAGACACTCACCCTGTCGACGGGCCCCACGCTGCCATCAGAAGCTGCGACGCCGGGAATGGAAGCCGCGCCGGCGC
AAGAAGCCGCCCCCGCGCAGGAAGCCACGGACAGGCCCGTAGCCGCCCCGGCACCGGAGGCCGCCGACACGCCTGTAGCC
GGGCCGGCGGCGCTGAGGTCACCGAAGCCGCCGCGGCGGCCCCGACCGGACCGCGCGGAGCTTCTCGCGGCCTACGGGAA
GACCGTTCCGGACCTCGTCGGTCCGGAGACCCGGGTGCTGCTGTGCGGTATCAATCCGTCCCTGGAGTCCGGCGCCACCG
GATTCCATTTCGGGACGCCCAGCAATCGGCTCTGGCCGGTCCTGCACTTCGCCGGGTTCACCGGGCGCCGGCTGCATCCG
TCCGAGACCGAGCACCTACGCGCCCGGGGCATCGGAATCACGAATCTGGTGCACCGCTCGACCGCTCGCGCCGATGAGAT
CGCTGACGACGAAATCAGGGCCGGTGTGCCGGTACTCATCGAGCTTGTCGAACGGATCCGCCCGGAATGGGTCGCCTTTC
TCGGGCTCGCCGCGTACCGCATCGGCTTCGGGCGGCGGACGGCGAAGGTCGGTCGACAGCCGGAGCGCATCGGTCCCGCC
GGGGTGTGGCTGCTACCGAACCCCAGTGGGCTGAACGCGCACTACCAGCTACCCGACCTTGTCCGGGTCTACGGCGAACT
GCGCGAGGCCGCCTTCGGGCCTGTCACGGCCACCACGCCGGCAGCGGGCCCGACCGCGGGTCCCGGACTCAGGTCCGGGC
ACGGCGGCGGCTGA

Upstream 100 bases:

>100_bases
CCGGCGCGGAGCGCCCTGATCTACGGCGGGCTGCCGCCAGCAATGGGATTCGGGTGGGGGTGGATGATTCGCAGGGGCGG
CGACAAACGAGGATGCCAGG

Downstream 100 bases:

>100_bases
CGGCGGCTGACGGCGGTCGGTGGCGCCGGCCGCCGCAAACGCCGAACGGCCCGGTGAACCGCGTACCTGCACGGTTCACC
GGGCCGTCCCGGTCACAGAG

Product: uracil-DNA glycosylase superfamily protein

Products: NA

Alternate protein names: Double-strand-specific uracil glycosylase; Mismatch-specific uracil DNA-glycosylase; MUG [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MASTRPPSQGTAPDQPSPADQTPEDTLPQTLTLSTGPTLPSEAATPGMEAAPAQEAAPAQEATDRPVAAPAPEAADTPVA
GPAALRSPKPPRRPRPDRAELLAAYGKTVPDLVGPETRVLLCGINPSLESGATGFHFGTPSNRLWPVLHFAGFTGRRLHP
SETEHLRARGIGITNLVHRSTARADEIADDEIRAGVPVLIELVERIRPEWVAFLGLAAYRIGFGRRTAKVGRQPERIGPA
GVWLLPNPSGLNAHYQLPDLVRVYGELREAAFGPVTATTPAAGPTAGPGLRSGHGGG

Sequences:

>Translated_297_residues
MASTRPPSQGTAPDQPSPADQTPEDTLPQTLTLSTGPTLPSEAATPGMEAAPAQEAAPAQEATDRPVAAPAPEAADTPVA
GPAALRSPKPPRRPRPDRAELLAAYGKTVPDLVGPETRVLLCGINPSLESGATGFHFGTPSNRLWPVLHFAGFTGRRLHP
SETEHLRARGIGITNLVHRSTARADEIADDEIRAGVPVLIELVERIRPEWVAFLGLAAYRIGFGRRTAKVGRQPERIGPA
GVWLLPNPSGLNAHYQLPDLVRVYGELREAAFGPVTATTPAAGPTAGPGLRSGHGGG
>Mature_296_residues
ASTRPPSQGTAPDQPSPADQTPEDTLPQTLTLSTGPTLPSEAATPGMEAAPAQEAAPAQEATDRPVAAPAPEAADTPVAG
PAALRSPKPPRRPRPDRAELLAAYGKTVPDLVGPETRVLLCGINPSLESGATGFHFGTPSNRLWPVLHFAGFTGRRLHPS
ETEHLRARGIGITNLVHRSTARADEIADDEIRAGVPVLIELVERIRPEWVAFLGLAAYRIGFGRRTAKVGRQPERIGPAG
VWLLPNPSGLNAHYQLPDLVRVYGELREAAFGPVTATTPAAGPTAGPGLRSGHGGG

Specific function: Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone o

COG id: COG3663

COG function: function code L; G:T/U mismatch-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TDG/mug DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI59853162, Length=182, Percent_Identity=28.021978021978, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789449, Length=163, Percent_Identity=46.0122699386503, Blast_Score=146, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356805, Length=192, Percent_Identity=30.7291666666667, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015637
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.28 [H]

Molecular weight: Translated: 31105; Mature: 30974

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTRPPSQGTAPDQPSPADQTPEDTLPQTLTLSTGPTLPSEAATPGMEAAPAQEAAPAQ
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCCCCHHHCCCCCCCCCCHHCCCCH
EATDRPVAAPAPEAADTPVAGPAALRSPKPPRRPRPDRAELLAAYGKTVPDLVGPETRVL
HHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCEEE
LCGINPSLESGATGFHFGTPSNRLWPVLHFAGFTGRRLHPSETEHLRARGIGITNLVHRS
EECCCCCHHCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
TARADEIADDEIRAGVPVLIELVERIRPEWVAFLGLAAYRIGFGRRTAKVGRQPERIGPA
HHHHHHHCCHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
GVWLLPNPSGLNAHYQLPDLVRVYGELREAAFGPVTATTPAAGPTAGPGLRSGHGGG
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASTRPPSQGTAPDQPSPADQTPEDTLPQTLTLSTGPTLPSEAATPGMEAAPAQEAAPAQ
CCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCCCCHHHCCCCCCCCCCHHCCCCH
EATDRPVAAPAPEAADTPVAGPAALRSPKPPRRPRPDRAELLAAYGKTVPDLVGPETRVL
HHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCEEE
LCGINPSLESGATGFHFGTPSNRLWPVLHFAGFTGRRLHPSETEHLRARGIGITNLVHRS
EECCCCCHHCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
TARADEIADDEIRAGVPVLIELVERIRPEWVAFLGLAAYRIGFGRRTAKVGRQPERIGPA
HHHHHHHCCHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
GVWLLPNPSGLNAHYQLPDLVRVYGELREAAFGPVTATTPAAGPTAGPGLRSGHGGG
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA