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The map label for this gene is recQ [H]

Identifier: 158317692

GI number: 158317692

Start: 7254946

End: 7257195

Strand: Reverse

Name: recQ [H]

Synonym: Franean1_5950

Alternate gene names: 158317692

Gene position: 7257195-7254946 (Counterclockwise)

Preceding gene: 158317693

Following gene: 158317689

Centisome position: 80.8

GC content: 73.91

Gene sequence:

>2250_bases
ATGGCGGATCAGGCGACGGTCAGCGGGACGCTGCGCGATCGGGCGGAGGAGCTGCTCCGGGCTCTGGCTGGGCCGGGCGC
GGTCCTGCGTGACGACCAGTGGCAGGCGATCGACGCGCTCGTCAGCGGGCGGCGGCGGGTGCTGCTCGTCCAGCGCACGG
GCTGGGGGAAGTCCGCGGTGTACTTCCTCGCCACGGCGCTGCTACGCGGTCTCGGCGACTCGGATCCGGGTGACTCGGAT
CCGGGTGACTCGGAACCAGGTGACTCGGAACCAGGTGACTCGGGTTCAAGCGGTCCGAGGCCGGGCGGCGGTCCGGCCGC
CCAGGTGGGGCCCACGGTGATCGTCTCCCCGCTGCTGGCGCTGATCCGCAACCAGGCGGCCGCGGCGGCACGGGTGGGCA
TCCGGGCCGGGGAGATCCATTCGGGGAACCTCACCGAGTGGGACGAGGTCTACGCCGCGCTGCGGGCGGGGGAGCTGGAC
CTGCTGCTCGTCGGCCCGGAGCGGCTGAACAACCCGACCTTCCGCGATGAGTACCTCCCGGAGCTCGCGGCCACGACGGG
GCTGCTTGTCGTCGACGAGGCGCACTGCATCTCCGACTGGGGCCACGACTTCCGTCCGGACTACCGCCGGCTGCGGTCAC
TGATCGGCGGGCTGCGGCCGGATGTGCCCGTGCTCGCGACGACCGCCACGGCCAACGCGCGGGTGGTCGAGGACGTCAGC
GAGCAGCTCGGGGCCGGCTCCACGAGCGCGGAGACCGTGGTCCTGCGGGGGTCTCTCGACCGGGAGAGCCTCCGGCTGGC
GGTTGTGTCGCTTCCCGCGGCCGAGCAGCGGTTCGGCTGGCTGGCCGACCATCTCGCAGAGCTACCCGGCTCCGGGATCA
TCTACACGCTCACCAAGCCGGGCGCGGAGGAGCTGACCGCGTTCCTTCGCGGCCAGGGCCACGAGGTGACGACCTACCAC
GGCGGCACGGAGCCGGCCGAGCGCATCGCCGCCGAGGAGGACCTGCTCGGCAACCGGGTGAAGGCGCTGGTGGCGACGAG
CGCTCTCGGGATGGGCTTCGACAAGCCCGATCTCGGGTTCGTCGTCCACGTCGGTGCGCCGAACTCGCCGATCGCCTACT
ACCAGCAGATCGGGCGGGCCGGGCGTGCGGTGGAGTCCGCCGAGGTCGTCCTGCTGCCCGCCACCGAGGACCGTGACATC
TGGCGGTACTTCGCCGACACGTCGTTCCCCCCGGAGCCGGTCGCCCGGCAGGTGCTGGACGTCCTGGCCCAGGCCGGGCG
GACGATGTCGACGCAGGCACTGCTCGCCGCCGTCGACCTGGGGCACTCCCGGCTCGAGCAGATGTTGAAGGTGCTCGACG
CGGACGGCGTCGTCCGGCGGGTCAAGGGCGGCTGGGAGGCGACGGGCGAGCCGTGGGTCTACGACGCCGAGCGCTTCCGT
CGCGTCGCCGCCGCGCGGGCCCGCGAGCAGCGGGCGATGCTCGACTACATCGCGACGCCGTCCTGCCGGATGGAGTTCCT
GCGCCACGCGCTCGACGATCCGTACGCGGTGCCGTGCGGCCGGTGTGACCGGTGCACCGGTCGGGTGTGGTCCACCGAGG
TCTCCTCCCGGTCGAGGGACAGCGCCCGCGAGGAGCTGCGCCGGACGGGCGTGCCCGTTGAGCCGCGCCGGATGTGGCCG
ACGGGCATGCGCACGCTGGGGGTCGCCGCGTCCGGCCGGATTCCCGCGTCGGTCACCGCCGAGCCCGGCCGCGTGGTCGC
ACGGCTCAACGACCTGGGCTGGGGCAACCGGCTGCGCCAGCTGTTCGCCCCTCCTCCCGAGGCCCAGGACGGCCCTGTCC
CCGACGACCTGTTCGAGGCGGTGGTGCGGACCCTGACCGAATGGCGGTGGGAGCGGCGCCCGGCGGCCGTGGTGACTGTG
GCGTCCAGGACACGCCCGTGCCTGGTGGCGGACCTCGGTGAACGGATCGCGGGTGTCGGGCGGCTGCCGTTGCTGGGGCA
GCTCCCCCGAGTGGCCGGCGGGCCCGCGGCCGGCCGGGTGCATAACAGCGCCCACCGCCTCGCCGGCCTGTGGTCGGCCT
TCGAGGTGCCACCGCCTATCGCCGGCCCGCTCGCCGAGCTGACCGGGCCGGTGCTGCTCGTCGACGACCTGATCGTCACG
GGCTGGACGATGACCGTCGCGGCCAGGGCGCTGCGCCAGGCCGGCGCGCCGGGCGTGCTGCCGTTCGCCCTCGCCGTCGA
GACCGGCTGA

Upstream 100 bases:

>100_bases
CCTGACGGCTCGCGCCCGCTCCGGTGACCGCGCCCGCGTCGCGGGCGGTTCCGGCGGCCGCGGGCCAGGAGCTGTCGGTG
GGGTCCGGTAGACAGGTGGC

Downstream 100 bases:

>100_bases
GCGGGCGGCACCGTGCCGGGATCACAGTGCCGAGACCAGAGCGCCGGGATTACCACGCCGGGATCACCGCGTCGGCTGGC
GAGCAGCCTCCTTCCGGGTG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 748

Protein sequence:

>749_residues
MADQATVSGTLRDRAEELLRALAGPGAVLRDDQWQAIDALVSGRRRVLLVQRTGWGKSAVYFLATALLRGLGDSDPGDSD
PGDSEPGDSEPGDSGSSGPRPGGGPAAQVGPTVIVSPLLALIRNQAAAAARVGIRAGEIHSGNLTEWDEVYAALRAGELD
LLLVGPERLNNPTFRDEYLPELAATTGLLVVDEAHCISDWGHDFRPDYRRLRSLIGGLRPDVPVLATTATANARVVEDVS
EQLGAGSTSAETVVLRGSLDRESLRLAVVSLPAAEQRFGWLADHLAELPGSGIIYTLTKPGAEELTAFLRGQGHEVTTYH
GGTEPAERIAAEEDLLGNRVKALVATSALGMGFDKPDLGFVVHVGAPNSPIAYYQQIGRAGRAVESAEVVLLPATEDRDI
WRYFADTSFPPEPVARQVLDVLAQAGRTMSTQALLAAVDLGHSRLEQMLKVLDADGVVRRVKGGWEATGEPWVYDAERFR
RVAAARAREQRAMLDYIATPSCRMEFLRHALDDPYAVPCGRCDRCTGRVWSTEVSSRSRDSAREELRRTGVPVEPRRMWP
TGMRTLGVAASGRIPASVTAEPGRVVARLNDLGWGNRLRQLFAPPPEAQDGPVPDDLFEAVVRTLTEWRWERRPAAVVTV
ASRTRPCLVADLGERIAGVGRLPLLGQLPRVAGGPAAGRVHNSAHRLAGLWSAFEVPPPIAGPLAELTGPVLLVDDLIVT
GWTMTVAARALRQAGAPGVLPFALAVETG

Sequences:

>Translated_749_residues
MADQATVSGTLRDRAEELLRALAGPGAVLRDDQWQAIDALVSGRRRVLLVQRTGWGKSAVYFLATALLRGLGDSDPGDSD
PGDSEPGDSEPGDSGSSGPRPGGGPAAQVGPTVIVSPLLALIRNQAAAAARVGIRAGEIHSGNLTEWDEVYAALRAGELD
LLLVGPERLNNPTFRDEYLPELAATTGLLVVDEAHCISDWGHDFRPDYRRLRSLIGGLRPDVPVLATTATANARVVEDVS
EQLGAGSTSAETVVLRGSLDRESLRLAVVSLPAAEQRFGWLADHLAELPGSGIIYTLTKPGAEELTAFLRGQGHEVTTYH
GGTEPAERIAAEEDLLGNRVKALVATSALGMGFDKPDLGFVVHVGAPNSPIAYYQQIGRAGRAVESAEVVLLPATEDRDI
WRYFADTSFPPEPVARQVLDVLAQAGRTMSTQALLAAVDLGHSRLEQMLKVLDADGVVRRVKGGWEATGEPWVYDAERFR
RVAAARAREQRAMLDYIATPSCRMEFLRHALDDPYAVPCGRCDRCTGRVWSTEVSSRSRDSAREELRRTGVPVEPRRMWP
TGMRTLGVAASGRIPASVTAEPGRVVARLNDLGWGNRLRQLFAPPPEAQDGPVPDDLFEAVVRTLTEWRWERRPAAVVTV
ASRTRPCLVADLGERIAGVGRLPLLGQLPRVAGGPAAGRVHNSAHRLAGLWSAFEVPPPIAGPLAELTGPVLLVDDLIVT
GWTMTVAARALRQAGAPGVLPFALAVETG
>Mature_748_residues
ADQATVSGTLRDRAEELLRALAGPGAVLRDDQWQAIDALVSGRRRVLLVQRTGWGKSAVYFLATALLRGLGDSDPGDSDP
GDSEPGDSEPGDSGSSGPRPGGGPAAQVGPTVIVSPLLALIRNQAAAAARVGIRAGEIHSGNLTEWDEVYAALRAGELDL
LLVGPERLNNPTFRDEYLPELAATTGLLVVDEAHCISDWGHDFRPDYRRLRSLIGGLRPDVPVLATTATANARVVEDVSE
QLGAGSTSAETVVLRGSLDRESLRLAVVSLPAAEQRFGWLADHLAELPGSGIIYTLTKPGAEELTAFLRGQGHEVTTYHG
GTEPAERIAAEEDLLGNRVKALVATSALGMGFDKPDLGFVVHVGAPNSPIAYYQQIGRAGRAVESAEVVLLPATEDRDIW
RYFADTSFPPEPVARQVLDVLAQAGRTMSTQALLAAVDLGHSRLEQMLKVLDADGVVRRVKGGWEATGEPWVYDAERFRR
VAAARAREQRAMLDYIATPSCRMEFLRHALDDPYAVPCGRCDRCTGRVWSTEVSSRSRDSAREELRRTGVPVEPRRMWPT
GMRTLGVAASGRIPASVTAEPGRVVARLNDLGWGNRLRQLFAPPPEAQDGPVPDDLFEAVVRTLTEWRWERRPAAVVTVA
SRTRPCLVADLGERIAGVGRLPLLGQLPRVAGGPAAGRVHNSAHRLAGLWSAFEVPPPIAGPLAELTGPVLLVDDLIVTG
WTMTVAARALRQAGAPGVLPFALAVETG

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI148612816, Length=448, Percent_Identity=28.7946428571429, Blast_Score=153, Evalue=7e-37,
Organism=Homo sapiens, GI51242947, Length=448, Percent_Identity=29.2410714285714, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI51242943, Length=448, Percent_Identity=28.7946428571429, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI4557365, Length=303, Percent_Identity=34.6534653465347, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI14591902, Length=292, Percent_Identity=30.4794520547945, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI14591904, Length=292, Percent_Identity=30.4794520547945, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI169218196, Length=425, Percent_Identity=27.5294117647059, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI110735439, Length=425, Percent_Identity=27.5294117647059, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI284005309, Length=326, Percent_Identity=30.3680981595092, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI45446747, Length=407, Percent_Identity=25.0614250614251, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI45446743, Length=407, Percent_Identity=25.0614250614251, Blast_Score=81, Evalue=5e-15,
Organism=Escherichia coli, GI48994977, Length=370, Percent_Identity=32.7027027027027, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI1787016, Length=220, Percent_Identity=26.8181818181818, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564293, Length=412, Percent_Identity=29.6116504854369, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25145561, Length=300, Percent_Identity=34.6666666666667, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71987997, Length=294, Percent_Identity=32.6530612244898, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71987993, Length=294, Percent_Identity=32.6530612244898, Blast_Score=153, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17552866, Length=323, Percent_Identity=30.9597523219814, Blast_Score=128, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323844, Length=377, Percent_Identity=29.973474801061, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646066, Length=297, Percent_Identity=34.006734006734, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI62472181, Length=316, Percent_Identity=34.8101265822785, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24664230, Length=316, Percent_Identity=34.8101265822785, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24664226, Length=304, Percent_Identity=35.1973684210526, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21358123, Length=410, Percent_Identity=26.8292682926829, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI18857967, Length=262, Percent_Identity=29.0076335877863, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80195; Mature: 80064

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00690 DEAH_ATP_HELICASE ; PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQATVSGTLRDRAEELLRALAGPGAVLRDDQWQAIDALVSGRRRVLLVQRTGWGKSAV
CCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHH
YFLATALLRGLGDSDPGDSDPGDSEPGDSEPGDSGSSGPRPGGGPAAQVGPTVIVSPLLA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHH
LIRNQAAAAARVGIRAGEIHSGNLTEWDEVYAALRAGELDLLLVGPERLNNPTFRDEYLP
HHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEECHHHCCCCCCCHHHHH
ELAATTGLLVVDEAHCISDWGHDFRPDYRRLRSLIGGLRPDVPVLATTATANARVVEDVS
HHHHHCCEEEEECHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHH
EQLGAGSTSAETVVLRGSLDRESLRLAVVSLPAAEQRFGWLADHLAELPGSGIIYTLTKP
HHHCCCCCCCCEEEEECCCCHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCC
GAEELTAFLRGQGHEVTTYHGGTEPAERIAAEEDLLGNRVKALVATSALGMGFDKPDLGF
CHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VVHVGAPNSPIAYYQQIGRAGRAVESAEVVLLPATEDRDIWRYFADTSFPPEPVARQVLD
EEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHH
VLAQAGRTMSTQALLAAVDLGHSRLEQMLKVLDADGVVRRVKGGWEATGEPWVYDAERFR
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEECHHHHH
RVAAARAREQRAMLDYIATPSCRMEFLRHALDDPYAVPCGRCDRCTGRVWSTEVSSRSRD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHHCCHH
SAREELRRTGVPVEPRRMWPTGMRTLGVAASGRIPASVTAEPGRVVARLNDLGWGNRLRQ
HHHHHHHHCCCCCCCCCCCCCCHHHHCEEECCCCCCCCCCCCCCEEHHHHHCCHHHHHHH
LFAPPPEAQDGPVPDDLFEAVVRTLTEWRWERRPAAVVTVASRTRPCLVADLGERIAGVG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
RLPLLGQLPRVAGGPAAGRVHNSAHRLAGLWSAFEVPPPIAGPLAELTGPVLLVDDLIVT
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEHHHHHH
GWTMTVAARALRQAGAPGVLPFALAVETG
HHHHHHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure 
ADQATVSGTLRDRAEELLRALAGPGAVLRDDQWQAIDALVSGRRRVLLVQRTGWGKSAV
CCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHH
YFLATALLRGLGDSDPGDSDPGDSEPGDSEPGDSGSSGPRPGGGPAAQVGPTVIVSPLLA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHH
LIRNQAAAAARVGIRAGEIHSGNLTEWDEVYAALRAGELDLLLVGPERLNNPTFRDEYLP
HHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEECHHHCCCCCCCHHHHH
ELAATTGLLVVDEAHCISDWGHDFRPDYRRLRSLIGGLRPDVPVLATTATANARVVEDVS
HHHHHCCEEEEECHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHH
EQLGAGSTSAETVVLRGSLDRESLRLAVVSLPAAEQRFGWLADHLAELPGSGIIYTLTKP
HHHCCCCCCCCEEEEECCCCHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCC
GAEELTAFLRGQGHEVTTYHGGTEPAERIAAEEDLLGNRVKALVATSALGMGFDKPDLGF
CHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VVHVGAPNSPIAYYQQIGRAGRAVESAEVVLLPATEDRDIWRYFADTSFPPEPVARQVLD
EEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHH
VLAQAGRTMSTQALLAAVDLGHSRLEQMLKVLDADGVVRRVKGGWEATGEPWVYDAERFR
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEECHHHHH
RVAAARAREQRAMLDYIATPSCRMEFLRHALDDPYAVPCGRCDRCTGRVWSTEVSSRSRD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHHCCHH
SAREELRRTGVPVEPRRMWPTGMRTLGVAASGRIPASVTAEPGRVVARLNDLGWGNRLRQ
HHHHHHHHCCCCCCCCCCCCCCHHHHCEEECCCCCCCCCCCCCCEEHHHHHCCHHHHHHH
LFAPPPEAQDGPVPDDLFEAVVRTLTEWRWERRPAAVVTVASRTRPCLVADLGERIAGVG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
RLPLLGQLPRVAGGPAAGRVHNSAHRLAGLWSAFEVPPPIAGPLAELTGPVLLVDDLIVT
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEHHHHHH
GWTMTVAARALRQAGAPGVLPFALAVETG
HHHHHHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]