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The map label for this gene is pccB [H]

Identifier: 158317656

GI number: 158317656

Start: 7184281

End: 7185936

Strand: Direct

Name: pccB [H]

Synonym: Franean1_5914

Alternate gene names: 158317656

Gene position: 7184281-7185936 (Clockwise)

Preceding gene: 158317653

Following gene: 158317657

Centisome position: 79.98

GC content: 67.63

Gene sequence:

>1656_bases
GTGAGACGGTCTCCACATCAATCGAGCACGTGGACCACCGACCGCCGTACGCTTCGCGGTATGGCTCTCCCGGCTTCCCC
GCAAGAACCGACGCCCGAACCGCACAGCACAGCCGGCCGCCTCGCCCGGCTGCAAGCGGTGACCGACGAGGCCGTCCATG
CCGGTTCGCAGCGCGCGGTGGACGCGCAGCACGCCAAGGGAAAGATGACGGCCCGGGAGCGGATCGAGGCGTTCCTCGAC
CCCGGCTCGTTCGTGGAGACGGACGCGTTCGCGCGCCACCGCTCGCACGACTTCGCGATGGACCGCAACCGCCCCTACGG
CGACGGCGTCGTCACCGGCTACGGCACGGTGGACGGCCGCCAGGTCTGCGTCTTCAGCCAGGACTTCACCGTCTTCGGCG
GGAGCCTGGGCGAGGTCTTCGGGGAGAAGATCGTCAAGATTATGGATCTCGCGCTCAGGACGGGAGTGCCGGTCGTCGGT
ATCAACGACTCCGGCGGCGCGCGGATCCAGGAGGGCGTCGTCTCGCTCGGCCTGTACGGGGAGATCTTCTACCGCAACGT
CATGGCGTCCGGCGTCGTGCCGCAGCTCTCGCTGATCATGGGCCCGTGTGCGGGCGGCGCGGTGTACTCACCCGCGATCA
CCGACTTCACGCTCATGGTCGACCAGACCAGTCACATGTTCATCACCGGCCCGGACGTGATCAAAGAGGTCACCGGCGAG
GACGTCGGCATGGAGGAGCTGGGTGGCGCCACCACCCACAACTCCCGCAGCGGCGTCGCGCACTTCCAGGCCGCGGACGA
GGCCGACTGCCTGGAGCTGGCCCGCGCCCTGCTGTCCTACCTGCCGTCGAACAACATGGACGAGGTGCCGGCCTACACCG
AGGTCGCCGACGTCGAGGCCGAGGTCGACCCGGAGCTCGACACGTTCATCCCGGATTCGCCGAACACCCCGTACGACATG
CACCATGTGATCGAGCGGATCCTGGACGAGGAGGACTTCCTCGAAGTCCACGCCCAGTTCGCACAGAACATGATCGTCGG
CTTCGGGCGCATCGACGGCCGCTCGGTCGGCGTCGTCGCCAACCAGCCGATGCAGTTCGCCGGCACCCTGGACATCGACG
CCAGCGAGAAGGCCGCGCGCTTCGTGCGCACCTGCGACGCGTTCAACATCCCGGTGCTGACGTTCGTGGACGTTCCCGGC
TTCCTGCCGGGAACGTCGCAGGAATGGAACGGCATCATCCGGCGCGGCGCCAAGCTCATCTACGCCTACGCCGAGGCGAC
CGTTCCCAAGGTGACGGTCATCACACGGAAGGCCTATGGCGGCGCCTATGACGTCATGGGTTCGAAGCATCTGCGCGCCG
ACATCAACCTGGCGTGGCCGACGGCCGAGATCGCCGTGATGGGTGCCCGCGGCGCGGTGAATATCATCTATCGCCGCGAG
CTCGCCGGCTCGGAAGCGCCCGAGCAGCGCCGCAGCGAACTGATCCAGGACTACACCGATCATTTCGCGACGCCGTACAT
CGCCGCGGAGCGCGGATACCTGGACGCCGTCATTCCGCCGTCGGTGACTCGGCGCGAGGTCATCCGGGCGCTGCGCCTGT
TGCGCACCAAGCGCGCGACGCTCCCGCCGAAGAAGCACGGCAACATCCCGCTGTAG

Upstream 100 bases:

>100_bases
CCTGCGACAGGGGGCGAGATGGCCGGCTCGACAGGGGCCGTTCGCCGCCCGGGGGATTCGGCGGGATGCACTGGCACGGG
ACCACCTTCCCAGAGGCATG

Downstream 100 bases:

>100_bases
GCCGCGGCATTCCGCCGGAGCCGGGATCGCGGGACCGAACGACCAAGGACCGAACGACAAAGGACCGAGGAGGAACGGCC
GGTGGCCGACAGACCCGACG

Product: carboxyl transferase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRRSPHQSSTWTTDRRTLRGMALPASPQEPTPEPHSTAGRLARLQAVTDEAVHAGSQRAVDAQHAKGKMTARERIEAFLD
PGSFVETDAFARHRSHDFAMDRNRPYGDGVVTGYGTVDGRQVCVFSQDFTVFGGSLGEVFGEKIVKIMDLALRTGVPVVG
INDSGGARIQEGVVSLGLYGEIFYRNVMASGVVPQLSLIMGPCAGGAVYSPAITDFTLMVDQTSHMFITGPDVIKEVTGE
DVGMEELGGATTHNSRSGVAHFQAADEADCLELARALLSYLPSNNMDEVPAYTEVADVEAEVDPELDTFIPDSPNTPYDM
HHVIERILDEEDFLEVHAQFAQNMIVGFGRIDGRSVGVVANQPMQFAGTLDIDASEKAARFVRTCDAFNIPVLTFVDVPG
FLPGTSQEWNGIIRRGAKLIYAYAEATVPKVTVITRKAYGGAYDVMGSKHLRADINLAWPTAEIAVMGARGAVNIIYRRE
LAGSEAPEQRRSELIQDYTDHFATPYIAAERGYLDAVIPPSVTRREVIRALRLLRTKRATLPPKKHGNIPL

Sequences:

>Translated_551_residues
MRRSPHQSSTWTTDRRTLRGMALPASPQEPTPEPHSTAGRLARLQAVTDEAVHAGSQRAVDAQHAKGKMTARERIEAFLD
PGSFVETDAFARHRSHDFAMDRNRPYGDGVVTGYGTVDGRQVCVFSQDFTVFGGSLGEVFGEKIVKIMDLALRTGVPVVG
INDSGGARIQEGVVSLGLYGEIFYRNVMASGVVPQLSLIMGPCAGGAVYSPAITDFTLMVDQTSHMFITGPDVIKEVTGE
DVGMEELGGATTHNSRSGVAHFQAADEADCLELARALLSYLPSNNMDEVPAYTEVADVEAEVDPELDTFIPDSPNTPYDM
HHVIERILDEEDFLEVHAQFAQNMIVGFGRIDGRSVGVVANQPMQFAGTLDIDASEKAARFVRTCDAFNIPVLTFVDVPG
FLPGTSQEWNGIIRRGAKLIYAYAEATVPKVTVITRKAYGGAYDVMGSKHLRADINLAWPTAEIAVMGARGAVNIIYRRE
LAGSEAPEQRRSELIQDYTDHFATPYIAAERGYLDAVIPPSVTRREVIRALRLLRTKRATLPPKKHGNIPL
>Mature_551_residues
MRRSPHQSSTWTTDRRTLRGMALPASPQEPTPEPHSTAGRLARLQAVTDEAVHAGSQRAVDAQHAKGKMTARERIEAFLD
PGSFVETDAFARHRSHDFAMDRNRPYGDGVVTGYGTVDGRQVCVFSQDFTVFGGSLGEVFGEKIVKIMDLALRTGVPVVG
INDSGGARIQEGVVSLGLYGEIFYRNVMASGVVPQLSLIMGPCAGGAVYSPAITDFTLMVDQTSHMFITGPDVIKEVTGE
DVGMEELGGATTHNSRSGVAHFQAADEADCLELARALLSYLPSNNMDEVPAYTEVADVEAEVDPELDTFIPDSPNTPYDM
HHVIERILDEEDFLEVHAQFAQNMIVGFGRIDGRSVGVVANQPMQFAGTLDIDASEKAARFVRTCDAFNIPVLTFVDVPG
FLPGTSQEWNGIIRRGAKLIYAYAEATVPKVTVITRKAYGGAYDVMGSKHLRADINLAWPTAEIAVMGARGAVNIIYRRE
LAGSEAPEQRRSELIQDYTDHFATPYIAAERGYLDAVIPPSVTRREVIRALRLLRTKRATLPPKKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=511, Percent_Identity=58.3170254403131, Blast_Score=593, Evalue=1e-169,
Organism=Homo sapiens, GI295821216, Length=531, Percent_Identity=56.120527306968, Blast_Score=580, Evalue=1e-165,
Organism=Homo sapiens, GI11545863, Length=483, Percent_Identity=30.8488612836439, Blast_Score=214, Evalue=1e-55,
Organism=Escherichia coli, GI1788655, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25147359, Length=541, Percent_Identity=54.7134935304991, Blast_Score=585, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI25147362, Length=527, Percent_Identity=55.4079696394687, Blast_Score=583, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17552936, Length=517, Percent_Identity=31.7214700193424, Blast_Score=252, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6323863, Length=297, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586065, Length=517, Percent_Identity=31.1411992263056, Blast_Score=245, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 60075; Mature: 60075

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSPHQSSTWTTDRRTLRGMALPASPQEPTPEPHSTAGRLARLQAVTDEAVHAGSQRAV
CCCCCCCCCCCCCHHHHHHCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DAQHAKGKMTARERIEAFLDPGSFVETDAFARHRSHDFAMDRNRPYGDGVVTGYGTVDGR
CHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCC
QVCVFSQDFTVFGGSLGEVFGEKIVKIMDLALRTGVPVVGINDSGGARIQEGVVSLGLYG
EEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHH
EIFYRNVMASGVVPQLSLIMGPCAGGAVYSPAITDFTLMVDQTSHMFITGPDVIKEVTGE
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEECHHHHHHHCCC
DVGMEELGGATTHNSRSGVAHFQAADEADCLELARALLSYLPSNNMDEVPAYTEVADVEA
CCCHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
EVDPELDTFIPDSPNTPYDMHHVIERILDEEDFLEVHAQFAQNMIVGFGRIDGRSVGVVA
CCCCCHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEE
NQPMQFAGTLDIDASEKAARFVRTCDAFNIPVLTFVDVPGFLPGTSQEWNGIIRRGAKLI
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCHHEE
YAYAEATVPKVTVITRKAYGGAYDVMGSKHLRADINLAWPTAEIAVMGARGAVNIIYRRE
EEEHHCCCCEEEEEEECCCCCCHHCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEHH
LAGSEAPEQRRSELIQDYTDHFATPYIAAERGYLDAVIPPSVTRREVIRALRLLRTKRAT
HCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCC
LPPKKHGNIPL
CCCCCCCCCCC
>Mature Secondary Structure
MRRSPHQSSTWTTDRRTLRGMALPASPQEPTPEPHSTAGRLARLQAVTDEAVHAGSQRAV
CCCCCCCCCCCCCHHHHHHCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DAQHAKGKMTARERIEAFLDPGSFVETDAFARHRSHDFAMDRNRPYGDGVVTGYGTVDGR
CHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCC
QVCVFSQDFTVFGGSLGEVFGEKIVKIMDLALRTGVPVVGINDSGGARIQEGVVSLGLYG
EEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHH
EIFYRNVMASGVVPQLSLIMGPCAGGAVYSPAITDFTLMVDQTSHMFITGPDVIKEVTGE
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEECHHHHHHHCCC
DVGMEELGGATTHNSRSGVAHFQAADEADCLELARALLSYLPSNNMDEVPAYTEVADVEA
CCCHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
EVDPELDTFIPDSPNTPYDMHHVIERILDEEDFLEVHAQFAQNMIVGFGRIDGRSVGVVA
CCCCCHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEE
NQPMQFAGTLDIDASEKAARFVRTCDAFNIPVLTFVDVPGFLPGTSQEWNGIIRRGAKLI
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCHHEE
YAYAEATVPKVTVITRKAYGGAYDVMGSKHLRADINLAWPTAEIAVMGARGAVNIIYRRE
EEEHHCCCCEEEEEEECCCCCCHHCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEHH
LAGSEAPEQRRSELIQDYTDHFATPYIAAERGYLDAVIPPSVTRREVIRALRLLRTKRAT
HCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCC
LPPKKHGNIPL
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]