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The map label for this gene is grsT [H]

Identifier: 158317522

GI number: 158317522

Start: 7014695

End: 7015471

Strand: Reverse

Name: grsT [H]

Synonym: Franean1_5776

Alternate gene names: 158317522

Gene position: 7015471-7014695 (Counterclockwise)

Preceding gene: 158317523

Following gene: 158317521

Centisome position: 78.11

GC content: 70.01

Gene sequence:

>777_bases
GTGGCGCGGACGTCCGCGCACGGGCAGTGGTTCCACCCGTCCGACCTGGAACCCGAGGCAGAGATCAGGCTCTTCCTGTT
CCCGCACGCCGGGAGCGGGGCCATCATCTACCGGGACTGGGCCGACCTGCTGCCGGCCGACGTGGGAGCGCAGGCCGTGA
CGCTGCCGGGCCGGCAGGGGCGCCGAGACGAGGTCGCCTTCACCGAGTGGGAGCCGTTGCTCGACGCGTTGTACGAAGCG
GTCCAGAACGAGTGCGACGAACGGCCGTTCGCGTTCTTCGGCCACTGCCTCGGCGCGCAGCTCGCCTACCACCTCGCCGT
CCGGATGCACCGAGCGCAGCAGCGCGTGCCGCTGCTCGTCGGGATGTCGGGATGGGCCCCGGAGGGGTTCTTCAACCCGA
CCAAGGAGCACATCGGGATGCCCCAGGAAGAACTCGTCGTCTGGATCAAGCGGCTCGGGTCGTTCCCGGCGGAGATCTAC
GACAATCCCGAGATGCTGCAGATGGTGGTGCCGGCCTTGCGGGCGGACCTGTCGGTGGCCGCGCAGCGGATCGACGAGGG
CGCGCTGGTGCCCTGCCCGATGGCGTCCTACGGCGGCAAGGCCGACCCGTTGATGGAGGAGACCGACGCCTTCTCGTCCT
GGGTGTCCCGCAGCCCCCAGTACCTTGGCCACACCGAGTACACCGGCGGCCACTTCTTCATCGACCAGCACGCCCTCGCG
GTGACCGCCGACTTCAGCCGGCACCTTCACCGCCTGGCAGCCGCCGCGCGGAGCTGA

Upstream 100 bases:

>100_bases
CGGCGGTACGCGCCGCGGGATGACGGGCGACGACGTGCCCGGCGGGCACGTCCGTCCGACCGGACCACCATCTTCAGGAG
GTACCGTGAGTAGCTCGATC

Downstream 100 bases:

>100_bases
CGGCTCGGGGTTGCGCCGCGCGGGGGGCGGTCGCGCCCAGTCGTTACCCCTGACGTAATCGACGAGAACGGTCGTCGTCT
GCCACGATGCCGACATGAGC

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MARTSAHGQWFHPSDLEPEAEIRLFLFPHAGSGAIIYRDWADLLPADVGAQAVTLPGRQGRRDEVAFTEWEPLLDALYEA
VQNECDERPFAFFGHCLGAQLAYHLAVRMHRAQQRVPLLVGMSGWAPEGFFNPTKEHIGMPQEELVVWIKRLGSFPAEIY
DNPEMLQMVVPALRADLSVAAQRIDEGALVPCPMASYGGKADPLMEETDAFSSWVSRSPQYLGHTEYTGGHFFIDQHALA
VTADFSRHLHRLAAAARS

Sequences:

>Translated_258_residues
MARTSAHGQWFHPSDLEPEAEIRLFLFPHAGSGAIIYRDWADLLPADVGAQAVTLPGRQGRRDEVAFTEWEPLLDALYEA
VQNECDERPFAFFGHCLGAQLAYHLAVRMHRAQQRVPLLVGMSGWAPEGFFNPTKEHIGMPQEELVVWIKRLGSFPAEIY
DNPEMLQMVVPALRADLSVAAQRIDEGALVPCPMASYGGKADPLMEETDAFSSWVSRSPQYLGHTEYTGGHFFIDQHALA
VTADFSRHLHRLAAAARS
>Mature_257_residues
ARTSAHGQWFHPSDLEPEAEIRLFLFPHAGSGAIIYRDWADLLPADVGAQAVTLPGRQGRRDEVAFTEWEPLLDALYEAV
QNECDERPFAFFGHCLGAQLAYHLAVRMHRAQQRVPLLVGMSGWAPEGFFNPTKEHIGMPQEELVVWIKRLGSFPAEIYD
NPEMLQMVVPALRADLSVAAQRIDEGALVPCPMASYGGKADPLMEETDAFSSWVSRSPQYLGHTEYTGGHFFIDQHALAV
TADFSRHLHRLAAAARS

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=223, Percent_Identity=23.7668161434978, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI8922871, Length=189, Percent_Identity=23.2804232804233, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28738; Mature: 28607

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTSAHGQWFHPSDLEPEAEIRLFLFPHAGSGAIIYRDWADLLPADVGAQAVTLPGRQG
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECHHHHCCCCCCCCEEECCCCCC
RRDEVAFTEWEPLLDALYEAVQNECDERPFAFFGHCLGAQLAYHLAVRMHRAQQRVPLLV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
GMSGWAPEGFFNPTKEHIGMPQEELVVWIKRLGSFPAEIYDNPEMLQMVVPALRADLSVA
ECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHH
AQRIDEGALVPCPMASYGGKADPLMEETDAFSSWVSRSPQYLGHTEYTGGHFFIDQHALA
HHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEE
VTADFSRHLHRLAAAARS
EEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARTSAHGQWFHPSDLEPEAEIRLFLFPHAGSGAIIYRDWADLLPADVGAQAVTLPGRQG
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECHHHHCCCCCCCCEEECCCCCC
RRDEVAFTEWEPLLDALYEAVQNECDERPFAFFGHCLGAQLAYHLAVRMHRAQQRVPLLV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
GMSGWAPEGFFNPTKEHIGMPQEELVVWIKRLGSFPAEIYDNPEMLQMVVPALRADLSVA
ECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHH
AQRIDEGALVPCPMASYGGKADPLMEETDAFSSWVSRSPQYLGHTEYTGGHFFIDQHALA
HHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEE
VTADFSRHLHRLAAAARS
EEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]