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The map label for this gene is fabF [H]

Identifier: 158317502

GI number: 158317502

Start: 6992644

End: 6993864

Strand: Reverse

Name: fabF [H]

Synonym: Franean1_5754

Alternate gene names: 158317502

Gene position: 6993864-6992644 (Counterclockwise)

Preceding gene: 158317503

Following gene: 158317501

Centisome position: 77.86

GC content: 74.61

Gene sequence:

>1221_bases
ATGGCCGGGCCGGAAGTCTCGATCAGCGGGGTGGGGCTGGTCACGCCCGGCGGGGTGGGGGTGGCCGCGAGCTGGGCGGC
GGTCTGCGCCGGCCGCCCGACCGCGAGCCTCGACCCGAGCCTGGCGGACGGCCTGGTCCAAATCGCCTGCCGAGTCCCGG
ACTTCGCTCCCGACCTGCTGCTCGGTGGTCAACGCGCGCATCGGCTGGACCCGTTCGTGCAGTTCGCCCTGGTGGCGGCG
GGGGAGGCGATCGCCGACGCCGGGCTGGACCCGGCCAGCTGGGACGGTGCCCGCGTCGGCGTCGTGCTGGGCTGCGCCGA
CGGCGGCCCGGGAACCGTCGAGGCGCAGCACCGGGTGCTGATCGAGCGCGGGCTGGCCCAGCTTTCCCCGCTGCTGCTGC
CGATGCAGTTGCCCAACATGCTCGCGGGGCAGGCCGCGATCGAGTTCGGTGCCACCGGGCCGAACCTGGTCGTCTCGACT
GCCTGCGCGTCCGGGGCGACCGCGATCGGCGTCGCGCGCGACCTGCTGGCGATGGACCGGTGCGACGTCGTCCTGGCGGG
TGGCAGCGAAGCGATGATCACACCGTTGGTGATGGCGGGATTCGCCCGGATGCGGGCGCTGTCCCGGCGGGCGCACGACC
CGGCCAGCGCCTCGCGCCCGTTCGACGTCGACCGCGACGGGTTCGTCGCGGGGGAGGGCGCGGGCGTGCTGGTCCTCGAG
CGGCTCGCCGACGCCCGGGCCCGGGGTGCCCGGGTACGCGCTCGCCTCGTCGGGTATGGCGCCAGCGCCGACGCCCATCA
CATCACCAGCCCGCACCCGTCCGGCCGAGGGATCGAGGCGGCGGTCCTGGCCGCGCTGGCTGACGCCGACGCGGCTCCGG
AGCAGGTGCGGCACGTCAACGCGCACGGCACCGGTACGCCGCTCAACGACCTGGTGGAAGGACAGCTCCTCAGCCGACTG
TTCACCAGCGGACCGTTGGTCACCTCGACCAAGGGGACGACCGGGCACCTGCTGGGGGCGGCTGGCGCGGTGGAGGCCGT
GTTCAGCACCCTCACTGTCGAGCAGGGCCTGGTGCCGCCCACGACCGGCCTGCGGACCCTCGACCCGCGGCTGGACATCG
ACGTGGCGACCGTGGCGACCGCTGCGGCGCCCGACTTCGTCCTGAGCAACTCGCTCGGGTTCGGCGGCCAGAACGCGGTG
CTCGCGATCGCCAAGGCGTGA

Upstream 100 bases:

>100_bases
CCACGGAGTTCGGGCTGGGCATCAGCGACGACGAACTCCTCGAGACCACGACCATCGGCGGCATCGCCGACCTGATGGCG
CAGCGGAGCATGGCGAGCTG

Downstream 100 bases:

>100_bases
GGTCGCGCGCGTGAACCGCGGCGGCGAGCCGCGCGGGCGTCGACGACGCAGGAGGGAGTTCGGCCGTGCACGACGTCCGT
GAGTTGCTGGACCTGAGCAC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAGPEVSISGVGLVTPGGVGVAASWAAVCAGRPTASLDPSLADGLVQIACRVPDFAPDLLLGGQRAHRLDPFVQFALVAA
GEAIADAGLDPASWDGARVGVVLGCADGGPGTVEAQHRVLIERGLAQLSPLLLPMQLPNMLAGQAAIEFGATGPNLVVST
ACASGATAIGVARDLLAMDRCDVVLAGGSEAMITPLVMAGFARMRALSRRAHDPASASRPFDVDRDGFVAGEGAGVLVLE
RLADARARGARVRARLVGYGASADAHHITSPHPSGRGIEAAVLAALADADAAPEQVRHVNAHGTGTPLNDLVEGQLLSRL
FTSGPLVTSTKGTTGHLLGAAGAVEAVFSTLTVEQGLVPPTTGLRTLDPRLDIDVATVATAAAPDFVLSNSLGFGGQNAV
LAIAKA

Sequences:

>Translated_406_residues
MAGPEVSISGVGLVTPGGVGVAASWAAVCAGRPTASLDPSLADGLVQIACRVPDFAPDLLLGGQRAHRLDPFVQFALVAA
GEAIADAGLDPASWDGARVGVVLGCADGGPGTVEAQHRVLIERGLAQLSPLLLPMQLPNMLAGQAAIEFGATGPNLVVST
ACASGATAIGVARDLLAMDRCDVVLAGGSEAMITPLVMAGFARMRALSRRAHDPASASRPFDVDRDGFVAGEGAGVLVLE
RLADARARGARVRARLVGYGASADAHHITSPHPSGRGIEAAVLAALADADAAPEQVRHVNAHGTGTPLNDLVEGQLLSRL
FTSGPLVTSTKGTTGHLLGAAGAVEAVFSTLTVEQGLVPPTTGLRTLDPRLDIDVATVATAAAPDFVLSNSLGFGGQNAV
LAIAKA
>Mature_405_residues
AGPEVSISGVGLVTPGGVGVAASWAAVCAGRPTASLDPSLADGLVQIACRVPDFAPDLLLGGQRAHRLDPFVQFALVAAG
EAIADAGLDPASWDGARVGVVLGCADGGPGTVEAQHRVLIERGLAQLSPLLLPMQLPNMLAGQAAIEFGATGPNLVVSTA
CASGATAIGVARDLLAMDRCDVVLAGGSEAMITPLVMAGFARMRALSRRAHDPASASRPFDVDRDGFVAGEGAGVLVLER
LADARARGARVRARLVGYGASADAHHITSPHPSGRGIEAAVLAALADADAAPEQVRHVNAHGTGTPLNDLVEGQLLSRLF
TSGPLVTSTKGTTGHLLGAAGAVEAVFSTLTVEQGLVPPTTGLRTLDPRLDIDVATVATAAAPDFVLSNSLGFGGQNAVL
AIAKA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=40.5727923627685, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI223972627, Length=157, Percent_Identity=43.9490445859873, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI41872631, Length=346, Percent_Identity=27.4566473988439, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=40.0485436893204, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI1788663, Length=336, Percent_Identity=35.7142857142857, Blast_Score=185, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=33.0120481927711, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=38.671875, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI212642053, Length=358, Percent_Identity=27.3743016759777, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=282, Percent_Identity=24.822695035461, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=439, Percent_Identity=33.9407744874715, Blast_Score=209, Evalue=6e-55,
Organism=Drosophila melanogaster, GI24644341, Length=414, Percent_Identity=42.2705314009662, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24581345, Length=357, Percent_Identity=27.4509803921569, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221330659, Length=349, Percent_Identity=26.647564469914, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920632, Length=349, Percent_Identity=26.647564469914, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 40818; Mature: 40687

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPEVSISGVGLVTPGGVGVAASWAAVCAGRPTASLDPSLADGLVQIACRVPDFAPDLL
CCCCCEEECEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHH
LGGQRAHRLDPFVQFALVAAGEAIADAGLDPASWDGARVGVVLGCADGGPGTVEAQHRVL
CCCCHHHHCCHHHHHHHHHHCHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHH
IERGLAQLSPLLLPMQLPNMLAGQAAIEFGATGPNLVVSTACASGATAIGVARDLLAMDR
HHHHHHHHHHHEECHHCCHHHHHHHHEEECCCCCCEEEEEHHCCCCHHHHHHHHHHHHCC
CDVVLAGGSEAMITPLVMAGFARMRALSRRAHDPASASRPFDVDRDGFVAGEGAGVLVLE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHH
RLADARARGARVRARLVGYGASADAHHITSPHPSGRGIEAAVLAALADADAAPEQVRHVN
HHHHHHHHCHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHEEC
AHGTGTPLNDLVEGQLLSRLFTSGPLVTSTKGTTGHLLGAAGAVEAVFSTLTVEQGLVPP
CCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TTGLRTLDPRLDIDVATVATAAAPDFVLSNSLGFGGQNAVLAIAKA
CCCCEECCCCCCEEHHHHHHHCCCCHHEECCCCCCCCCEEEEEECC
>Mature Secondary Structure 
AGPEVSISGVGLVTPGGVGVAASWAAVCAGRPTASLDPSLADGLVQIACRVPDFAPDLL
CCCCEEECEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHH
LGGQRAHRLDPFVQFALVAAGEAIADAGLDPASWDGARVGVVLGCADGGPGTVEAQHRVL
CCCCHHHHCCHHHHHHHHHHCHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHH
IERGLAQLSPLLLPMQLPNMLAGQAAIEFGATGPNLVVSTACASGATAIGVARDLLAMDR
HHHHHHHHHHHEECHHCCHHHHHHHHEEECCCCCCEEEEEHHCCCCHHHHHHHHHHHHCC
CDVVLAGGSEAMITPLVMAGFARMRALSRRAHDPASASRPFDVDRDGFVAGEGAGVLVLE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHH
RLADARARGARVRARLVGYGASADAHHITSPHPSGRGIEAAVLAALADADAAPEQVRHVN
HHHHHHHHCHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHEEC
AHGTGTPLNDLVEGQLLSRLFTSGPLVTSTKGTTGHLLGAAGAVEAVFSTLTVEQGLVPP
CCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TTGLRTLDPRLDIDVATVATAAAPDFVLSNSLGFGGQNAVLAIAKA
CCCCEECCCCCCEEHHHHHHHCCCCHHEECCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 11152607 [H]