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The map label for this gene is polC [H]

Identifier: 158317483

GI number: 158317483

Start: 6969816

End: 6970529

Strand: Direct

Name: polC [H]

Synonym: Franean1_5735

Alternate gene names: 158317483

Gene position: 6969816-6970529 (Clockwise)

Preceding gene: 158317482

Following gene: 158317485

Centisome position: 77.6

GC content: 72.55

Gene sequence:

>714_bases
ATGGCGTGGTGGCAGCGCCCGATGGCCGTGCTCGATTTCGAGACGACCGGAACCGACGTGGAGACCGACCGGGCTGTTCA
GGTCGCGCTCCTGAAGGTCGGCCCGACCGGGGTGCTGAACCAGCTCTGCCAGATCATCGATCCGGGCGTCGACGTCCCGG
AGGCGGCGGCGCGCATACACGGGATCACAACGGAGCGTGCCCGCCGCGAGGGTCGTGATCCCGCCGAGGTGCTCGGCCGG
GTCGGCCAGGCGCTGGAGGGCGTGTGGCGCGACGGCATCCCCGTCGTCATCATGAACAGCTCGTTCGACCTGACGCTCCT
CGACCGCGAGCTGCGCCGCCACCACGGCCGCAGCCTCGCCGAGGCTGACATGCTCGTCCTCGACCCCATGGTGATCGACC
GTGAGCTCGATCCGCGCCGGCCCGGCAAGCGCACGCTGACCGCGCTCGCCACCCACTACCGCGTCCGGCAGGAAGGCGCC
CACGACGCGCTCGCGGACTGCCTGACCACGGCCAGGATCGCCTGGCGTCTCCCGCGGATGCATCCCGACTGGGCCGCGAT
GGGCCTGACCGCGCTCCAGGGCTGGCAGGCCGACGCGCACCGCCGCTGGGCCGAGGACTACCAGTCGTACCTGCGCCGCC
GCGGTGGGCGGCCGGACGCCGTCATCGACACCAGCTGGCCGTGGCGCCCGCTCGACGTCACCGCGGGAGTCTGA

Upstream 100 bases:

>100_bases
CCCCTGCTTCGGGCCCGCGCCGTCCGGTGGAATGACGGTGTTCATCCCCTGGCCCCGGTGTGACGGCGTCCCCGGGCTGT
TCCGAGGAGACGACCGGACG

Downstream 100 bases:

>100_bases
GCGGGCGCTGGCCGCGAAACCGGAAGCTGCCCTGGCCCAGATCCACCTCGGGCGCCGAGAACCCGGCGGCCAGGAGCCGG
TGTCCGCTCTTGGTCCAGGG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MAWWQRPMAVLDFETTGTDVETDRAVQVALLKVGPTGVLNQLCQIIDPGVDVPEAAARIHGITTERARREGRDPAEVLGR
VGQALEGVWRDGIPVVIMNSSFDLTLLDRELRRHHGRSLAEADMLVLDPMVIDRELDPRRPGKRTLTALATHYRVRQEGA
HDALADCLTTARIAWRLPRMHPDWAAMGLTALQGWQADAHRRWAEDYQSYLRRRGGRPDAVIDTSWPWRPLDVTAGV

Sequences:

>Translated_237_residues
MAWWQRPMAVLDFETTGTDVETDRAVQVALLKVGPTGVLNQLCQIIDPGVDVPEAAARIHGITTERARREGRDPAEVLGR
VGQALEGVWRDGIPVVIMNSSFDLTLLDRELRRHHGRSLAEADMLVLDPMVIDRELDPRRPGKRTLTALATHYRVRQEGA
HDALADCLTTARIAWRLPRMHPDWAAMGLTALQGWQADAHRRWAEDYQSYLRRRGGRPDAVIDTSWPWRPLDVTAGV
>Mature_236_residues
AWWQRPMAVLDFETTGTDVETDRAVQVALLKVGPTGVLNQLCQIIDPGVDVPEAAARIHGITTERARREGRDPAEVLGRV
GQALEGVWRDGIPVVIMNSSFDLTLLDRELRRHHGRSLAEADMLVLDPMVIDRELDPRRPGKRTLTALATHYRVRQEGAH
DALADCLTTARIAWRLPRMHPDWAAMGLTALQGWQADAHRRWAEDYQSYLRRRGGRPDAVIDTSWPWRPLDVTAGV

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26673; Mature: 26542

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWWQRPMAVLDFETTGTDVETDRAVQVALLKVGPTGVLNQLCQIIDPGVDVPEAAARIH
CCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHH
GITTERARREGRDPAEVLGRVGQALEGVWRDGIPVVIMNSSFDLTLLDRELRRHHGRSLA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHH
EADMLVLDPMVIDRELDPRRPGKRTLTALATHYRVRQEGAHDALADCLTTARIAWRLPRM
HCCHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
HPDWAAMGLTALQGWQADAHRRWAEDYQSYLRRRGGRPDAVIDTSWPWRPLDVTAGV
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AWWQRPMAVLDFETTGTDVETDRAVQVALLKVGPTGVLNQLCQIIDPGVDVPEAAARIH
CCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHH
GITTERARREGRDPAEVLGRVGQALEGVWRDGIPVVIMNSSFDLTLLDRELRRHHGRSLA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHH
EADMLVLDPMVIDRELDPRRPGKRTLTALATHYRVRQEGAHDALADCLTTARIAWRLPRM
HCCHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
HPDWAAMGLTALQGWQADAHRRWAEDYQSYLRRRGGRPDAVIDTSWPWRPLDVTAGV
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA