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The map label for this gene is galE [H]

Identifier: 158317410

GI number: 158317410

Start: 6873295

End: 6874284

Strand: Direct

Name: galE [H]

Synonym: Franean1_5661

Alternate gene names: 158317410

Gene position: 6873295-6874284 (Clockwise)

Preceding gene: 158317409

Following gene: 158317411

Centisome position: 76.52

GC content: 74.75

Gene sequence:

>990_bases
GTGCGCATCCTCGTCACCGGCGCGTCCGGGTTCGTCGGCGGCGTCACCGCCGACCTGCTCTCGGCCGCCGGCCACCAGGT
GACCGCGCTCGTCCGGGACGCGACGGCCCGGACGAGGCTGTCGAGGGTGATCGAGGTGGTCCAGGCCGACCTGCTCGAAC
CACGCCAGCTCGCCGCGGCGGGCGTCAGCCGCGGGTTCGACGGGGTGTGCCACCTCGCCGCTCTGACCAGGGTGCGGGAG
TCCCGCGAGACGCCGCTGCGGTACTTCGCGGCGAACGTCACGGGCACGACCAACCTGCTGGCGGCCCTCGACGCGGGCAC
CCGGGCCACCGGGGTGGCCCCGCGGTTCGTCTTCGGCTCGAGCTGCGCCGTCTACGGGGACACGGGTACCTCCCCTATCC
CGGAGACACGCGCACCCGCGCCGACGAATCCCTACGGCGCCTCGAAACTCGCCGCGGAGCAGGCGGTGGCCTACCAGGCC
GCCACCGGGCGGCTGGGCGCCGTCGTGCTGCGCTCGTTCAACGTCGCGGGGGCGGTCGGCTCGCACGCCGACCGCGACAG
CAGCCGGATCATCCCGGCCGCGCTCGGCGTCGCAACGGGCCGGCGCGACGCCTTCCGGGTGAACGGTGACGGCGCGTCGA
TCCGCGAGTACGTCCACGTCGTCGACATGGCGCGGGCGTACCTGACCGCGCTGCGGGCGACCGTGCCGGGCCGCTGCACC
GTCTACAACGTCGGCAGCGGCCTCGGCGTGAGCGTCACCGACGTGCTGCGGACGGTGGAGAGCGTGACGGGCCGGGACGT
GCCGCGGGTGACCCTGCCCCCGGTGCCCGAACCCAGAGCGCTCATCGCCGACAGCCGCCGCATCCGGGCCGACCTGGGCT
GGACCTCTCCGTCCTCGACCATCGAGAAGATCGTCACGGATGCCTGGCGCTCGACGGCGGTGCCCGAGCCGGTCGCGGCG
CGGCGCGGCGACGTCCCGATCGTCTCGTGA

Upstream 100 bases:

>100_bases
CTCGCTCCCTCCGCCGCCGCCTGCCTGGAGCTCGCCTGGCGCCACCGGGAGACCCTCCTGCCCGGGTTGCGCATGCGGGC
ATCGGTCTGATCAGGCCGCT

Downstream 100 bases:

>100_bases
CGGCGGTGTCCGTCGACCCGTCAGCGATTTCCGGCGGGCTTTCGCCGGTATGCCCGATCGGCTCCGGGCCGGCGTGACAC
GATGACTGCGGCCGAAGCCC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRILVTGASGFVGGVTADLLSAAGHQVTALVRDATARTRLSRVIEVVQADLLEPRQLAAAGVSRGFDGVCHLAALTRVRE
SRETPLRYFAANVTGTTNLLAALDAGTRATGVAPRFVFGSSCAVYGDTGTSPIPETRAPAPTNPYGASKLAAEQAVAYQA
ATGRLGAVVLRSFNVAGAVGSHADRDSSRIIPAALGVATGRRDAFRVNGDGASIREYVHVVDMARAYLTALRATVPGRCT
VYNVGSGLGVSVTDVLRTVESVTGRDVPRVTLPPVPEPRALIADSRRIRADLGWTSPSSTIEKIVTDAWRSTAVPEPVAA
RRGDVPIVS

Sequences:

>Translated_329_residues
MRILVTGASGFVGGVTADLLSAAGHQVTALVRDATARTRLSRVIEVVQADLLEPRQLAAAGVSRGFDGVCHLAALTRVRE
SRETPLRYFAANVTGTTNLLAALDAGTRATGVAPRFVFGSSCAVYGDTGTSPIPETRAPAPTNPYGASKLAAEQAVAYQA
ATGRLGAVVLRSFNVAGAVGSHADRDSSRIIPAALGVATGRRDAFRVNGDGASIREYVHVVDMARAYLTALRATVPGRCT
VYNVGSGLGVSVTDVLRTVESVTGRDVPRVTLPPVPEPRALIADSRRIRADLGWTSPSSTIEKIVTDAWRSTAVPEPVAA
RRGDVPIVS
>Mature_329_residues
MRILVTGASGFVGGVTADLLSAAGHQVTALVRDATARTRLSRVIEVVQADLLEPRQLAAAGVSRGFDGVCHLAALTRVRE
SRETPLRYFAANVTGTTNLLAALDAGTRATGVAPRFVFGSSCAVYGDTGTSPIPETRAPAPTNPYGASKLAAEQAVAYQA
ATGRLGAVVLRSFNVAGAVGSHADRDSSRIIPAALGVATGRRDAFRVNGDGASIREYVHVVDMARAYLTALRATVPGRCT
VYNVGSGLGVSVTDVLRTVESVTGRDVPRVTLPPVPEPRALIADSRRIRADLGWTSPSSTIEKIVTDAWRSTAVPEPVAA
RRGDVPIVS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI7657641, Length=277, Percent_Identity=24.9097472924188, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=24.6753246753247, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=32.3442136498516, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788353, Length=344, Percent_Identity=28.1976744186047, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=354, Percent_Identity=30.225988700565, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71982038, Length=356, Percent_Identity=30.0561797752809, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17568069, Length=321, Percent_Identity=27.1028037383178, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=341, Percent_Identity=30.791788856305, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=30.3834808259587, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34292; Mature: 34292

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGASGFVGGVTADLLSAAGHQVTALVRDATARTRLSRVIEVVQADLLEPRQLAAA
CEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
GVSRGFDGVCHLAALTRVRESRETPLRYFAANVTGTTNLLAALDAGTRATGVAPRFVFGS
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCEEECC
SCAVYGDTGTSPIPETRAPAPTNPYGASKLAAEQAVAYQAATGRLGAVVLRSFNVAGAVG
CEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCC
SHADRDSSRIIPAALGVATGRRDAFRVNGDGASIREYVHVVDMARAYLTALRATVPGRCT
CCCCCCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VYNVGSGLGVSVTDVLRTVESVTGRDVPRVTLPPVPEPRALIADSRRIRADLGWTSPSST
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCHHH
IEKIVTDAWRSTAVPEPVAARRGDVPIVS
HHHHHHHHHHHCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MRILVTGASGFVGGVTADLLSAAGHQVTALVRDATARTRLSRVIEVVQADLLEPRQLAAA
CEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
GVSRGFDGVCHLAALTRVRESRETPLRYFAANVTGTTNLLAALDAGTRATGVAPRFVFGS
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCEEECC
SCAVYGDTGTSPIPETRAPAPTNPYGASKLAAEQAVAYQAATGRLGAVVLRSFNVAGAVG
CEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCC
SHADRDSSRIIPAALGVATGRRDAFRVNGDGASIREYVHVVDMARAYLTALRATVPGRCT
CCCCCCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VYNVGSGLGVSVTDVLRTVESVTGRDVPRVTLPPVPEPRALIADSRRIRADLGWTSPSST
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCHHH
IEKIVTDAWRSTAVPEPVAARRGDVPIVS
HHHHHHHHHHHCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8921853; 12948626 [H]